Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(993 produtos)
- ACK(1 produtos)
- AChR(612 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.004 produtos)
- BACE(36 produtos)
- Beta Amilóide(216 produtos)
- CaMK(71 produtos)
- COX(592 produtos)
- Receptor de Dopamina(433 produtos)
- Receptor GABA(355 produtos)
- Gama-secretase(63 produtos)
- GluR(261 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(381 produtos)
- LRRK2(41 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(15 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(310 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5516 produtos de "Neurociência"
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NO 711
CAS:NO 711（NNC-711 free acid） is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.Fórmula:C21H22N2O3Pureza:99.70%Cor e Forma:SolidPeso molecular:350.41Deramciclane
CAS:Deramciclane has high affinity for 5-HT2A and 5-HT2C receptors.Fórmula:C20H31NOCor e Forma:SolidPeso molecular:301.47JI051
CAS:JI051 has anti-tumor effects and can interact with PHB2 to inhibit the proliferation of HEK293 cells and pancreatic cancer cells.Fórmula:C22H24N2O3Pureza:≥98% - ≥98.0%Cor e Forma:SolidPeso molecular:364.44RO 4938581
CAS:RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).Fórmula:C13H8BrF2N5Pureza:98%Cor e Forma:SolidPeso molecular:352.14Org-25935
CAS:Org-25935, a GlyT-1 inhibitor, is used potentially for the treatment of schizophrenia and alcohol dependence.Fórmula:C21H26ClNO3Cor e Forma:SolidPeso molecular:375.89(R)-(+)-8-Hydroxy-DPAT hydrobromide
CAS:5-HT1A serotonin receptor agonistFórmula:C16H26BrNOPureza:98%Cor e Forma:SolidPeso molecular:328.29BuChE-IN-3
CAS:<p>BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE (IC50: 8.3 nM). buChE-IN-3 is a mild antioxidant, non-toxic, lipophilic and neuroprotective agent.</p>Fórmula:C21H21F2N3O4SCor e Forma:SolidPeso molecular:449.47Ro4491533
CAS:Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).Fórmula:C24H20F3N3OCor e Forma:SolidPeso molecular:423.43MAO-B ligand-1
CAS:MAO-B ligand-1 is a selective MAO-B inhibitor.Fórmula:C19H19N5O4SCor e Forma:SolidPeso molecular:413.45Carburazepam
CAS:Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.Fórmula:C17H16ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:329.78(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:broad spectrum EAA agonist/antagonistFórmula:C9H9NO5Pureza:98%Cor e Forma:SolidPeso molecular:211.17sEH/AChE-IN-1
CAS:<p>Compound 12a is a dual sEH/AChE inhibitor with potential for treating Alzheimer's-related neuroinflammation and memory loss.</p>Fórmula:C29H31ClF3N5O3Cor e Forma:SolidPeso molecular:590.04Phenglutarimid
CAS:Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.Fórmula:C17H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:288.38SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Fórmula:C18H18N4O2Pureza:98%Cor e Forma:SolidPeso molecular:322.36Usmarapride
CAS:Usmarapride (SUVN-D4010) is an oral 5-HT4 receptor agonist, crosses BBB, with an EC50 of 44 nM, for Alzheimer's research.Fórmula:C23H31N5O6Cor e Forma:SolidPeso molecular:473.53A-85380 HCl
CAS:A-85380 is an agonist of nicotinic acetylcholine receptor.Fórmula:C9H14Cl2N2OCor e Forma:SolidPeso molecular:237.13Talsaclidine
CAS:Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.Fórmula:C10H15NOPureza:98%Cor e Forma:SolidPeso molecular:165.23Deramciclane fumarate
CAS:Deramciclane fumarate is a 5-HT(2A/C) antagonist with putative anxiolytic activity.Fórmula:C24H35NO5Cor e Forma:SolidPeso molecular:417.54ATC0065
CAS:ATC0065 is a melanin-concentrating hormone receptor 1 antagonist with oral activity.Fórmula:C25H29BrF3N5OCor e Forma:SolidPeso molecular:552.435-HT7 receptor ligand 1
CAS:Compound 5c: 5-HT7 receptor ligand, K i = 8 nM, not hepatotoxic, moderate CYP3A4/CYP2D6 interaction.Fórmula:C21H23N7Cor e Forma:SolidPeso molecular:373.45PXS-4787
CAS:PXS-4787 selectively inhibits LOX with IC50 values: 2 μM (Bovine), 3.2 μM (LOXL1), 0.6 μM (LOXL2), 1.4 μM (LOXL3), 0.2 μM (LOXL4).Fórmula:C10H12FNO2SCor e Forma:SolidPeso molecular:229.27GABAA receptor modulator-2
CAS:<p>Compound 20: Selective, oral α5-GABAAR inhibitor, Ki: 4.1 nM. High stability, CNS safe.</p>Fórmula:C22H22FN3O5SCor e Forma:SolidPeso molecular:459.49WAY-361789
CAS:WAY-361789 is an agonist of alpha7 nicotinic acetylcholine receptor.Fórmula:C22H31N5O3Cor e Forma:SolidPeso molecular:413.51VU0400195
CAS:VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).Fórmula:C21H16ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.82AY1511
CAS:<p>AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].</p>Fórmula:C17H14O6Cor e Forma:SolidPeso molecular:314.29LY 302148
CAS:<p>LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.</p>Fórmula:C19H23FN4Pureza:98%Cor e Forma:SolidPeso molecular:326.41ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Fórmula:C21H20FNO3Pureza:99.83%Cor e Forma:SolidPeso molecular:353.39Piclozotan
CAS:Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO)Fórmula:C23H24ClN3O2Pureza:98.59%Cor e Forma:SolidPeso molecular:409.91BHF-177
CAS:<p>BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.</p>Fórmula:C19H20F3N3Cor e Forma:SolidPeso molecular:347.38Muscarine chloride
CAS:Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Fórmula:C9H20ClNO2Cor e Forma:SolidPeso molecular:209.71Mavoglurant racemate
CAS:Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.Fórmula:C19H23NO3Pureza:98%Cor e Forma:SolidPeso molecular:313.39Muscarine iodide
CAS:Muscarinic acetylcholine receptor agonistFórmula:C9H20INO2Pureza:98%Cor e Forma:SolidPeso molecular:301.17LY-411575 isomer 1
CAS:<p>LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.</p>Fórmula:C26H23F2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:479.48Thiobencarb
CAS:<p>Thiobencarb (Siacarb), a thiocarbamate herbicide, is a cholinesterase inhibitor.</p>Fórmula:C12H16ClNOSPureza:99.63%Cor e Forma:Clear Colorless Liquid Thiobencarb Is A Pale Yellow To Brownish Yellow Liquid Non Corrosive Used As An HerbicidePeso molecular:257.78Melatonin receptor agonist 1
CAS:<p>Melatonin receptor agonist 1 (compound 20c) is a potent agonist of melatonin receptor (MT) with Ki values of 108 nM for MT2 and 1140 nM for MT 1 [1].</p>Fórmula:C15H19N3O2Cor e Forma:SolidPeso molecular:273.33VU0404251
CAS:<p>VU0404251 is a positive allosteric modulator of mGlu5.</p>Fórmula:C19H23FN2O2Cor e Forma:SolidPeso molecular:330.4Tacitin
CAS:<p>Tacitin (Benzoctamine Hydrochloride) shows sedative and anti-anxiety properties. Tacitin blocks the central postsynaptic serotonin receptors.</p>Fórmula:C18H20ClNPureza:98%Cor e Forma:SolidPeso molecular:285.81TC 1698 dihydrochloride
CAS:nicotinic α7 receptor agonistFórmula:C13H18N2Pureza:98%Cor e Forma:SolidPeso molecular:202.3BChE-IN-13
CAS:BChE-IN-13 (17c): Oral, potent, selective BChE inhibitor; IC50: eqBChE 0.22μM, hBChE 0.016μM; aids memory, Alzheimer's research.Fórmula:C24H28N2OCor e Forma:SolidPeso molecular:360.49CGS8216
CAS:CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.Fórmula:C16H11N3OPureza:98.53%Cor e Forma:SolidPeso molecular:261.28SB357134
CAS:SB357134 is a potent, selective and orally active antagonist of 5-HT6 receptor and shows nootropic effects in animal studies.Fórmula:C17H18Br2FN3O3SPureza:98%Cor e Forma:SolidPeso molecular:523.21M1 ligand 1
CAS:<p>Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.</p>Fórmula:C20H21NO2Cor e Forma:SolidPeso molecular:307.39(1S,3R)-ACPD
CAS:(1S,3R)-ACPD is a group I and II mGlu receptor agonist.Fórmula:C7H11NO4Pureza:98%Cor e Forma:SolidPeso molecular:173.17DS2
CAS:Positive allosteric modulator of δ-subunit containing GABAA receptorsFórmula:C18H12ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:353.83L-CCG-l
CAS:group II metabotropic glutamate receptor agonistFórmula:C6H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:159.14MK-0343
CAS:MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.Fórmula:C19H17F2N7OPureza:98%Cor e Forma:SolidPeso molecular:397.38Foliglurax monohydrochloride
CAS:Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.Fórmula:C23H24ClN3O3SCor e Forma:SolidPeso molecular:457.9717-PA
CAS:17-PA is a GABAA receptor antagonist.Fórmula:C25H34OPureza:98%Cor e Forma:SolidPeso molecular:350.54Prenylamine lactate
CAS:Prenylamine lactate, an ex-angina drug, depletes heart catecholamines and blocks calcium channels.Fórmula:C27H33NO3Pureza:98%Cor e Forma:SolidPeso molecular:419.56UCSF678
CAS:<p>UCSF678: selective 42 nM partial agonist at 5-HT5AR, fewer off-target effects, and lower assay risks than SB-699551.</p>Fórmula:C15H18N2O2SCor e Forma:SolidPeso molecular:290.38
