Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(642 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.005 produtos)
- BACE(37 produtos)
- Beta Amilóide(220 produtos)
- CaMK(73 produtos)
- COX(598 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(371 produtos)
- Gama-secretase(60 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(326 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5476 produtos de "Neurociência"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Pep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Fórmula:C51H87N17O13Cor e Forma:SolidPeso molecular:1146.34AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFórmula:C10H13N3OPureza:99.97%Cor e Forma:SolidPeso molecular:191.23(Iso)-Landipirdine
CAS:(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Fórmula:C18H19FN2O3SPureza:98.94%Cor e Forma:SoildPeso molecular:362.42Polyglutamine binding peptide 1
CAS:Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.Fórmula:C72H90N16O16Cor e Forma:SolidPeso molecular:1435.58AChE/BuChE-IN-4
CAS:AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.Fórmula:C17H23N5Pureza:99.98%Cor e Forma:SoildPeso molecular:297.4LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Fórmula:C28H39ClN2O2Cor e Forma:SolidPeso molecular:471.07Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Fórmula:C20H30O2Cor e Forma:SolidPeso molecular:302.45I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Fórmula:C21H23ClFN2O4PCor e Forma:SolidPeso molecular:452.845-HT5AR/5-HT6R ligand-1
5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6Iloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Fórmula:C23H25FN2O5Cor e Forma:SolidPeso molecular:428.465-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Fórmula:C24H26N4O2SCor e Forma:SolidPeso molecular:434.55Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Fórmula:C11H15BrClO3PSPureza:97.04% - 97.24%Cor e Forma:SolidPeso molecular:373.63Trivalent GalNAc-DBCO
CAS:Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne–azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.Fórmula:C91H144N12O34Pureza:96.33%Peso molecular:1950.182,6-DMA hydrochloride
CAS:2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Fórmula:C11H18ClNO2Cor e Forma:SolidPeso molecular:231.72Mosapride citrate dihydrate
CAS:Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.Fórmula:C27H35ClFN3O11Pureza:98%Cor e Forma:SolidPeso molecular:632.04C2-8
CAS:C2-8 inhibits polyQ aggregation, IC50=25 μM (HDQ51), 0.05 μM (PC12 cells), reduces neurodegeneration in Huntington's models.Fórmula:C19H14Br2N2O3SCor e Forma:SolidPeso molecular:510.2Pyrazolam
CAS:Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.Fórmula:C16H12BrN5Cor e Forma:SolidPeso molecular:354.2TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Fórmula:C12H17N3Pureza:99.81%Cor e Forma:SolidPeso molecular:203.28Imidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.368TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Fórmula:C15H16N2O3SCor e Forma:SolidPeso molecular:304.36
