Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(642 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.004 produtos)
- BACE(37 produtos)
- Beta Amilóide(220 produtos)
- CaMK(73 produtos)
- COX(598 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(371 produtos)
- Gama-secretase(60 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(326 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5476 produtos de "Neurociência"
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[D-Trp7,9,10]-Substance P
CAS:Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Fórmula:C79H105N21O13SPureza:98%Cor e Forma:SolidPeso molecular:1588.89isomer-Cilansetron
CAS:isomer-Cilansetron is an isomer of Cilansetron.Fórmula:C20H21N3OPureza:99.92% - 99.96%Cor e Forma:SoildPeso molecular:319.4(Iso)-Landipirdine
CAS:(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Fórmula:C18H19FN2O3SPureza:98.94%Cor e Forma:SoildPeso molecular:362.42CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Fórmula:C8H13ClN4OPureza:99.7%Cor e Forma:SoildPeso molecular:216.67Polyglutamine binding peptide 1
CAS:Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.Fórmula:C72H90N16O16Cor e Forma:SolidPeso molecular:1435.586,9-Dichloro-1,2,3,4-tetrahydroacridine
CAS:6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also anFórmula:C13H11Cl2NCor e Forma:SolidPeso molecular:252.1395-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Fórmula:C24H26N4O2SCor e Forma:SolidPeso molecular:434.55GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.26LY86057
CAS:LY86057 is a bioactive chemical.Fórmula:C20H26N2O3Cor e Forma:SolidPeso molecular:342.439Trivalent GalNAc-DBCO
CAS:Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne–azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.Fórmula:C91H144N12O34Pureza:96.33%Peso molecular:1950.18SCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Fórmula:C21H21ClF2O6S2Cor e Forma:SolidPeso molecular:506.97Imidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.368Notch 1
CAS:Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.Fórmula:C62H97N15O22S3Cor e Forma:SolidPeso molecular:1500.72AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities.Cor e Forma:Odour SolidRN341
RN341 is a LRRK2-specific type II kinase inhibitor (IC50 of 296 nM). It prevents the phosphorylation of LRRK2 by stabilizing an open conformation, thereby avoiding S935 dephosphorylation. Additionally, RN341 rescues LRRK2-mediated kinesin motility blockage by preventing microtubule binding. This compound effectively inhibits both wild-type and G2019S LRRK2 at the cellular level, offering a novel avenue for Parkinson's disease research.Cor e Forma:Odour SolidHTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Fórmula:C35H43Cl2F2N5O4Cor e Forma:SolidPeso molecular:706.65SAHM1 TFA
SAHM1 TFA inhibits the Notch pathway, stabilizes alpha helices, and blocks Notch complex formation.Fórmula:C96H163N36F3O25SCor e Forma:SolidPeso molecular:2310.6S-8510 free base
CAS:S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Fórmula:C12H10N4O2Cor e Forma:SolidPeso molecular:242.23M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Cor e Forma:Odour SolidLeiokinine A
CAS:Leiokinine A is a novel 4-quinolinone alkaloid.Fórmula:C14H17NO2Cor e Forma:SolidPeso molecular:231.29
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