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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5557 produtos de "Neurociência"

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  • 5-Methyltryptamine hydrochloride
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    5-Methyltryptamine hydrochloride

    CAS:
    5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.
    Fórmula:C11H15ClN2
    Pureza:99.45%
    Cor e Forma:Solid
    Peso molecular:210.703

    Ref: TM-T19813

  • Nicardipine pyridine metabolite II
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    Nicardipine pyridine metabolite II

    CAS:
    Nicardipine pyridine metabolite II is a biaoctive chemical.
    Fórmula:C26H27N3O6
    Cor e Forma:Solid
    Peso molecular:477.51

    Ref: TM-T33659

  • Aftin-5
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    Aftin-5

    CAS:
    Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.
    Fórmula:C19H26N6O
    Cor e Forma:Solid
    Peso molecular:354.45

    Ref: TM-T88257

  • Aβ1-42 aggregation inhibitor 1
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    Aβ1-42 aggregation inhibitor 1

    CAS:
    Aβ1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), demonstrating IC50 values of 2.64 μM and 1.29
    Fórmula:C29H32N4S
    Cor e Forma:Solid
    Peso molecular:468.66

    Ref: TM-T64238

  • VU0477886
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    VU0477886

    CAS:
    VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.
    Fórmula:C20H13ClN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:392.80

    Ref: TM-T29139

  • Penbutolol sulfate
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    Penbutolol sulfate

    CAS:
    Penbutolol sulfate ((-)-Terbuclomine) is able to bind to both β2-adrenergic receptor and β1-adrenergic receptor, thus making it a non-selective β blocker.
    Fórmula:C18H29NO2H2O4S
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:340.47

    Ref: TM-T12402

  • Logotipo do CymitQuimica
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    6-hydroxy Buspirone

    CAS:
    6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4.
    Fórmula:C21H31N5O3
    Peso molecular:401.50

    Ref: TM-T83909

  • 7-Acetoxy-1-methylquinolinium iodide
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    7-Acetoxy-1-methylquinolinium iodide

    CAS:
    7-Acetoxy-1-methylquinolinium iodide (AMQI) is a cholinesterase substrate for inhibitor detection with 320 nm Ex and 410 nm Em.
    Fórmula:C12H12INO2
    Cor e Forma:Solid
    Peso molecular:329.13

    Ref: TM-T40837

  • SB 271046 hydrochloride
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    SB 271046 hydrochloride

    CAS:
    SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist and is > 200-fold selective over 55 other receptors, enzymes and ion channels.
    Fórmula:C20H22ClN3O3S2·HCl
    Pureza:99.77%
    Cor e Forma:Solid
    Peso molecular:488.45

    Ref: TM-T4118

  • Dianicline dihydrochloride
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    Dianicline dihydrochloride

    CAS:
    Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.
    Fórmula:C13H16N2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:216.28

    Ref: TM-T15112

  • Hydroxy ziprasidone
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    Hydroxy ziprasidone

    CAS:
    Hydroxy ziprasidone is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a 5-HT and dopamine receptor antagonist.
    Fórmula:C21H21ClN4O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:428.94

    Ref: TM-T11586

  • Catestatin
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    Catestatin

    CAS:
    Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.
    Fórmula:C107H173N37O26S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2425.84

    Ref: TM-TP2058

  • Aprofene
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    Aprofene

    CAS:
    Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.
    Fórmula:C21H27NO2
    Cor e Forma:Solid
    Peso molecular:325.44

    Ref: TM-T25104

  • 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
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    4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine

    CAS:
    4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).
    Fórmula:C14H11BrN2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:319.22

    Ref: TM-T19142

  • Ketanserinol
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    Ketanserinol

    CAS:
    <p>Ketanserinol is a metabolite of the antihypertensive drug ketanserin, which blocks 5-HT2 receptors to treat protamine-induced pulmonary hypertension.</p>
    Fórmula:C22H24FN3O3
    Cor e Forma:Solid
    Peso molecular:397.44

    Ref: TM-T25568

  • Diclofensine
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    Diclofensine

    CAS:
    Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine.
    Fórmula:C17H17Cl2NO
    Pureza:97.01% - 98.13%
    Cor e Forma:Solid
    Peso molecular:322.23

    Ref: TM-T7341

  • Biperiden lactate
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    Biperiden lactate

    CAS:
    <p>Biperiden lactate is a biochemical.</p>
    Fórmula:C24H35NO4
    Cor e Forma:Solid
    Peso molecular:401.54

    Ref: TM-T30456

  • Pardoprunox
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    Pardoprunox

    CAS:
    Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.
    Fórmula:C12H15N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:233.27

    Ref: TM-T1769

  • VU0029767
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    VU0029767

    CAS:
    <p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>
    Fórmula:C21H21N3O3
    Cor e Forma:Solid
    Peso molecular:363.41

    Ref: TM-T200818

  • 7-Desmethyl-3-hydroxyagomelatine
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    7-Desmethyl-3-hydroxyagomelatine

    CAS:
    7-Desmethyl-3-hydroxyagomelatine, less active than parent drug Agomelatine, is a melatonergic agonist and 5-HT2C antagonist.
    Fórmula:C14H15NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:245.27

    Ref: TM-T10192