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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5398 produtos de "Neurociência"

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  • Logotipo do CymitQuimica
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    5-HT1A antagonist 1

    <p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>
    Fórmula:C23H29ClN6O2
    Cor e Forma:Solid
    Peso molecular:456.97

    Ref: TM-T62843

  • Rodatristat
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    Rodatristat

    CAS:
    <p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>
    Fórmula:C27H27ClF3N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:561.98

    Ref: TM-T16780

  • hAChE/Aβ1-42-IN-1
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    hAChE/Aβ1-42-IN-1

    CAS:
    <p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>
    Fórmula:C20H24N6O
    Cor e Forma:Solid
    Peso molecular:364.44

    Ref: TM-T61388

  • Alixorexton
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    Alixorexton

    CAS:
    <p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>
    Fórmula:C21H30N2O5S
    Cor e Forma:Solid
    Peso molecular:422.538

    Ref: TM-T205053

  • Sulamserod hydrochloride
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    Sulamserod hydrochloride

    CAS:
    <p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>
    Fórmula:C19H29Cl2N3O5S
    Cor e Forma:Solid
    Peso molecular:482.42

    Ref: TM-T201756

  • MAO-B-IN-40
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    MAO-B-IN-40

    CAS:
    <p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>
    Fórmula:C17H15N3O3
    Cor e Forma:Solid
    Peso molecular:309.319

    Ref: TM-T206123

  • 5-HT1A modulator 4
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    5-HT1A modulator 4

    CAS:
    <p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>
    Fórmula:C9H14N4
    Cor e Forma:Solid
    Peso molecular:178.234

    Ref: TM-T205724

  • AChE-IN-83
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    AChE-IN-83

    CAS:
    <p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>
    Fórmula:C10H7ClN2O2S
    Cor e Forma:Solid
    Peso molecular:254.693

    Ref: TM-T205656

  • Logotipo do CymitQuimica
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    BChE-IN-3

    <p>BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.</p>
    Fórmula:C26H41N3O2
    Cor e Forma:Solid
    Peso molecular:427.62

    Ref: TM-T62336

  • LRRK2-IN-16
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    LRRK2-IN-16

    CAS:
    <p>LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.</p>
    Fórmula:C18H19N5OS
    Cor e Forma:Solid
    Peso molecular:353.441

    Ref: TM-T204380

  • Serotonin maleate
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    Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Fórmula:C14H16N2O5
    Cor e Forma:Solid
    Peso molecular:292.287

    Ref: TM-T204388

  • Glutaminyl Cyclase Inhibitor 3
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    Glutaminyl Cyclase Inhibitor 3

    CAS:
    <p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>
    Fórmula:C24H32N6O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:468.61

    Ref: TM-T11422

  • PTCA
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    PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Fórmula:C10H5Cl2NO2S
    Cor e Forma:Solid
    Peso molecular:274.123

    Ref: TM-T204835

  • Logotipo do CymitQuimica
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    SB 258741 hydrochloride

    <p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>
    Fórmula:C19H31ClN2O2S
    Cor e Forma:Solid
    Peso molecular:386.98

    Ref: TM-T61724

  • R-96544 hydrochloride
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    R-96544 hydrochloride

    CAS:
    <p>5-HT2 receptor antagonist</p>
    Fórmula:C22H29NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:355.47

    Ref: TM-T23219

  • HW161023
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    HW161023

    CAS:
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Fórmula:C20H24F2N4O
    Cor e Forma:Solid
    Peso molecular:374.428

    Ref: TM-T206896

  • LY 215840
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    LY 215840

    CAS:
    <p>5-HT2/5-HT7 receptor antagonist</p>
    Fórmula:C24H33N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:395.54

    Ref: TM-T22940

  • Terguride
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    Terguride

    CAS:
    <p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>
    Fórmula:C20H28N4O
    Cor e Forma:Solid
    Peso molecular:340.46

    Ref: TM-T71847

  • Revexepride
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    Revexepride

    CAS:
    <p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>
    Fórmula:C21H32ClN3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:425.95

    Ref: TM-T16737

  • AChE/BuChE-IN-3
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    AChE/BuChE-IN-3

    CAS:
    <p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>
    Fórmula:C30H30F3N3O6
    Cor e Forma:Solid
    Peso molecular:585.57

    Ref: TM-T64137