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Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

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Foram encontrados 1372 produtos de "Tirosina Quinase/Adaptador"

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  • Calcineurin substrate
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    Calcineurin substrate

    CAS:
    <p>Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase.</p>
    Fórmula:C92H150N28O29
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2112.35

    Ref: TM-TP1485

  • Logotipo do CymitQuimica
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    Necitumumab

    CAS:
    <p>Necitumumab (IMC-11F8) is a human monoclonal antibody against EGFR, an anti-angiogenic agent used in the treatment of advanced non-small cell lung cancer.</p>
    Pureza:97.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 99.1% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:145.5 kDa

    Ref: TM-T77459

  • Motesanib Diphosphate
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    Motesanib Diphosphate

    CAS:
    <p>Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic</p>
    Fórmula:C22H23N5O·2H3PO4
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:569.44

    Ref: TM-T2288L

  • Arginyl-Glutamine
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    Arginyl-Glutamine

    CAS:
    <p>Arginyl-Glutamine (Arg-Gln) is a dipeptide nutritional supplement that protects neonatal mice from hyperoxia-induced lung injury, lowering VEGF levels.</p>
    Fórmula:C11H22N6O4
    Pureza:95.2%
    Cor e Forma:Solid
    Peso molecular:302.33

    Ref: TM-T76574

  • Logotipo do CymitQuimica
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    Mecbotamab vedotin

    CAS:
    <p>Mecbotamab vedotin (BA301) is an inhibitory IgG1 antibody that targets human tyrosine kinase receptor AXL and the humanized murine monoclonal BA301 γ1 chain. It can be utilized in the preparation of immunoconjugates for research into cancers expressing the Axl type.</p>
    Cor e Forma:Liquid

    Ref: TM-T9901A-225

  • Logotipo do CymitQuimica
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    DSPE-PEG2000-GE11

    <p>DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01177

  • Logotipo do CymitQuimica
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    Cetuximab MMAE

    <p>Cetuximab-MMAE, an antibody-drug conjugate (ADC), combines an EGFR-targeting antibody with Monomethyl auristatin E (MMAE) to investigate colorectal and head and neck cancers.</p>
    Cor e Forma:Liquid
    Peso molecular:150 kDa

    Ref: TM-T9901A-219

  • Logotipo do CymitQuimica
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    PROTAC EGFR degrader 2

    <p>Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.</p>
    Fórmula:C58H72ClFN12O8S
    Cor e Forma:Solid
    Peso molecular:1151.78

    Ref: TM-T74333

  • PD-149163 hydrochloride
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    PD-149163 hydrochloride

    PD-149163 hydrochloride is a neurokinin B agonist with antipsychotic activity, used for research on neurological diseases.
    Fórmula:C42H72ClN9O6
    Cor e Forma:Solid
    Peso molecular:834.53

    Ref: TM-T70271L

  • KN1022
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    KN1022

    CAS:
    <p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>
    Fórmula:C21H22N6O5
    Pureza:99.68%
    Cor e Forma:Soild
    Peso molecular:438.44

    Ref: TM-T60110

  • Logotipo do CymitQuimica
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    Antiproliferative agent-57

    <p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T200522

  • MS9449
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    MS9449

    CAS:
    <p>MS9449 is a powerful EGFR PROTAC; Kd: 17 nM (WT), 10 nM (L858R); targets mutant EGFRs via UPS and autophagy; hinders NSCLC cell growth.</p>
    Fórmula:C60H76ClFN10O8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1151.82

    Ref: TM-T74635

  • Logotipo do CymitQuimica
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    EGFR-IN-43

    <p>EGFR-IN-43 (17c) is a potent EGFR inhibitor with ER antagonist action, tamoxifen/endoxifen+gefitinib linkage, and strong anticancer activity.</p>
    Fórmula:C50H55ClFN5O5
    Cor e Forma:Solid
    Peso molecular:860.45

    Ref: TM-T74458

  • KYL peptide
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    KYL peptide

    CAS:
    <p>EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines &amp; LTP; long half-life (8-12h), neuroprotective.</p>
    Fórmula:C74H108N14O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1465.75

    Ref: TM-TP1895

  • EGFR-IN-15
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    EGFR-IN-15

    CAS:
    <p>EGFR-IN-15 (compound I-005) is a potent EGFR inhibitor, exhibiting an IC50 value of 4 nM. This compound holds potential for oncological research applications.</p>
    Fórmula:C24H25BrN6O2
    Cor e Forma:Solid
    Peso molecular:509.408

    Ref: TM-T40209

  • Logotipo do CymitQuimica
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    (Pro3) GIP, human

    CAS:
    <p>(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.</p>
    Fórmula:C226H338N60O64S
    Cor e Forma:Solid
    Peso molecular:4951.53

    Ref: TM-T76313

  • Logotipo do CymitQuimica
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    Istiratumab

    CAS:
    <p>Istiratumab (M-6495) is a bispecific antibody against IGF-1R/ErbB3 for cancer research, promoting receptor degradation.</p>
    Cor e Forma:Liquid

    Ref: TM-T77044

  • PCI-33380
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    PCI-33380

    CAS:
    <p>PCI-33380 is an irreversible inhibitor of Bruton's Tyrosine Kinase.</p>
    Fórmula:C46H52BF2N11O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:855.8

    Ref: TM-T16441

  • Leucettine L41
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    Leucettine L41

    CAS:
    <p>Leucettine L41 (LeucettineL41) is an inhibitor of DYRKs/CLKs, preferentially targeting DYRK1A, and inhibits DYRK2.</p>
    Fórmula:C17H13N3O3
    Pureza:99.08%
    Cor e Forma:Solid
    Peso molecular:307.3

    Ref: TM-T24402

  • Logotipo do CymitQuimica
    Targetmol
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    Acetyl Gastric Inhibitory Peptide (human)

    CAS:
    <p>Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.</p>
    Fórmula:C228H340N60O67S
    Cor e Forma:Solid
    Peso molecular:5025.6

    Ref: TM-T76310