Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(118 products)
- EGFR(582 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2382 products of "Angiogenesis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purity:97.63% - 98.92%Color and Shape:SolidMolecular weight:691.61SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formula:C18H22N4O4Purity:99.74%Color and Shape:SolidMolecular weight:358.39Ref: TM-T6012
1mg34.00€2mg46.00€5mg70.00€10mg105.00€25mg215.00€50mg304.00€100mg427.00€200mg587.00€1mL*10mM (DMSO)79.00€UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formula:C19H25ClN8Purity:99.52%Color and Shape:SolidMolecular weight:400.91Ref: TM-T2056L
1mg84.00€5mg168.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)185.00€Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.03Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purity:98.7% - 99.90%Color and Shape:SolidMolecular weight:554.64Ref: TM-T4485
1mg46.00€2mg59.00€5mg96.00€10mg130.00€25mg215.00€50mg309.00€100mg444.00€200mg655.00€1mL*10mM (DMSO)104.00€ZINC13466751
CAS:ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).Formula:C20H21N5O2Purity:99.8%Color and Shape:SolidMolecular weight:363.41PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22Ref: TM-T6932
1mg37.00€2mg50.00€5mg63.00€10mg94.00€25mg146.00€50mg210.00€100mg294.00€1mL*10mM (DMSO)52.00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Ref: TM-T1792L
5mg34.00€10mg46.00€25mg65.00€50mg94.00€100mg133.00€200mg197.00€500mg329.00€1mL*10mM (DMSO)55.00€Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purity:96.17% - 99.85%Color and Shape:SolidMolecular weight:557.04RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63Vactosertib
CAS:Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formula:C22H18FN7Purity:98.85% - 99.81%Color and Shape:SolidMolecular weight:399.42JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ibuprofen Lysine
CAS:Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formula:C19H32N2O4Purity:99.26%Color and Shape:CoaMolecular weight:352.47BIIB068
CAS:BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formula:C23H29N7O2Purity:97.98%Color and Shape:SolidMolecular weight:435.52Ref: TM-T9192
1mg46.00€5mg90.00€10mg152.00€25mg264.00€50mg398.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)100.00€(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurity:99.24%Color and Shape:SolidMolecular weight:386.45Ref: TM-T10626
1mg44.00€2mg57.00€5mg93.00€10mg120.00€25mg215.00€50mg313.00€100mg439.00€200mg628.00€1mL*10mM (DMSO)92.00€2,4-DPD
CAS:2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)Formula:C11H13NO4Purity:99.74%Color and Shape:Yellow Solid CrystallineMolecular weight:223.23Silymarin
CAS:Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.Formula:C25H22O10Purity:98%Color and Shape:Yellow And Brown PowderMolecular weight:482.441PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formula:C16H14BrN3O2Purity:98.47% - 99.29%Color and Shape:SolidMolecular weight:360.21Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:SolidMolecular weight:450.34Ref: TM-T1661
2mgTo inquire5mg33.00€10mg49.00€25mg55.00€50mg64.00€100mg88.00€500mg147.00€1mL*10mM (DMSO)50.00€Tucatinib
CAS:Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Formula:C26H24N8O2Purity:99.05% - 99.96%Color and Shape:SolidMolecular weight:480.52Ref: TM-T2364
1g1,071.00€2mg34.00€5mg50.00€10mg74.00€25mg117.00€50mg177.00€100mg333.00€500mg782.00€1mL*10mM (DMSO)82.00€Poziotinib
CAS:Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formula:C23H21Cl2FN4O3Purity:98.69% - 99.78%Color and Shape:SolidMolecular weight:491.34SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormula:C32H40ClF2N6O13PPurity:98.07%Color and Shape:SolidMolecular weight:821.12Ref: TM-T5349
1mg35.00€2mg50.00€5mg74.00€10mg113.00€25mg200.00€50mg333.00€100mg495.00€1mL*10mM (DMSO)102.00€NCGC00262650
CAS:NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
Formula:C18H20N4OPurity:98%Color and Shape:SolidMolecular weight:308.38PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:98% - 98.21%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg44.00€5mg65.00€10mg110.00€25mg178.00€50mg304.00€100mg482.00€200mg687.00€1mL*10mM (DMSO)71.00€CEP-28122 mesylate salt
CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.Formula:C29H39ClN6O6SColor and Shape:SolidMolecular weight:635.17BMS-536924
CAS:BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormula:C25H26ClN5O3Purity:99.02%Color and Shape:SolidMolecular weight:479.96Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Ref: TM-T2487
1mg42.00€2mg52.00€5mg74.00€10mg101.00€25mg175.00€50mg268.00€100mg409.00€200mg573.00€500mg888.00€1mL*10mM (DMSO)81.00€BMS817378
CAS:BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).Formula:C24H18ClF2N4O7PPurity:>99.99%Color and Shape:SolidMolecular weight:578.85Theliatinib tartrate
CAS:Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.Formula:C29H32N6O8Color and Shape:SolidMolecular weight:592.6MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formula:C20H20N2OPurity:98.17% - 99.754%Color and Shape:SolidMolecular weight:304.39Ref: TM-T6886
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg245.00€50mg358.00€100mg537.00€1mL*10mM (DMSO)90.00€(Rac)-JBJ-04-125-02
CAS:(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.Formula:C29H26FN5O3SPurity:97.57%Color and Shape:SolidMolecular weight:543.61Ref: TM-T8872
1mg100.00€5mg205.00€10mg334.00€25mg567.00€50mg807.00€100mg1,099.00€1mL*10mM (DMSO)249.00€Onatasertib
CAS:Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formula:C21H27N5O3Purity:99.14% - 99.93%Color and Shape:SolidMolecular weight:397.47TAS0728
CAS:TAS0728 is a HER2 inhibitor, with antitumor activityFormula:C26H32N8O3Purity:97.78%Color and Shape:SolidMolecular weight:504.58Ref: TM-T7819
1mg48.00€5mg105.00€10mg166.00€25mg304.00€50mg485.00€100mg658.00€200mg888.00€1mL*10mM (DMSO)111.00€WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purity:99.21%Color and Shape:SolidMolecular weight:297.31Blu-782
CAS:Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formula:C31H42N6O4Purity:99.51%Color and Shape:SolidMolecular weight:562.7FGFR2-IN-3 hydrochloride
CAS:FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.Formula:C28H25ClFN7O2Color and Shape:SolidMolecular weight:546.0AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purity:99.62%Color and Shape:SolidMolecular weight:496.36Ref: TM-T4249
2mg34.00€5mg46.00€10mg62.00€25mg94.00€50mg167.00€100mg265.00€200mg385.00€1mL*10mM (DMSO)49.00€Tranilast
CAS:Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormula:C18H17NO5Purity:99.67% - >99.99%Color and Shape:White With Light Yellow Crystalline PowderMolecular weight:327.33Ref: TM-T2690
5mg43.00€10mg55.00€25mg66.00€50mg93.00€100mg119.00€200mg175.00€500mg298.00€1mL*10mM (DMSO)55.00€PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formula:C18H24N6OPurity:99.98%Color and Shape:SolidMolecular weight:340.42Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formula:C24H27ClN4O3Color and Shape:SolidMolecular weight:454.95SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35JCN037
CAS:JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Formula:C16H11BrFN3O2Purity:99.5%Color and Shape:SolidMolecular weight:376.18Tolimidone
CAS:Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
Formula:C11H10N2O2Purity:99.85% - 99.85%Color and Shape:SolidMolecular weight:202.21TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formula:C32H36N8O3Purity:97.16% - 98.12%Color and Shape:SolidMolecular weight:580.68R-268712
CAS:R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formula:C20H18FN5OPurity:99.61%Color and Shape:SolidMolecular weight:363.39Ref: TM-T16708
1mg44.00€5mg93.00€10mg130.00€25mg250.00€50mg378.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)92.00€Vadimezan
CAS:Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity.Formula:C17H14O4Purity:97.38% - 99.8%Color and Shape:SolidMolecular weight:282.29Ref: TM-T6273
2mg39.00€5mg58.00€10mg93.00€25mg172.00€50mg268.00€100mg401.00€200mg580.00€1mL*10mM (DMSO)89.00€Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formula:C24H23ClFN5O2Purity:98.37% - 99.84%Color and Shape:Off-White SolidMolecular weight:467.92PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48
