Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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BMH-9
CAS:BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C19H27N3O2Color and Shape:SolidMolecular weight:329.44L 741742 (free base)
CAS:L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).Formula:C23H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:380.91ALC67
CAS:ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.Formula:C15H15NO3SPurity:98%Color and Shape:SolidMolecular weight:289.35EGFR-IN-57
CAS:EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.Formula:C22H15N3O2SColor and Shape:SolidMolecular weight:385.44Dabuzalgron HCl
CAS:Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.Formula:C12H17Cl2N3O3SPurity:98%Color and Shape:SolidMolecular weight:354.25Topoisomerase II inhibitor 11
CAS:Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).Formula:C27H21BrCl2N2O2SColor and Shape:SolidMolecular weight:588.34Fomesafen
CAS:Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).Formula:C15H10ClF3N2O6SPurity:99.91% - 99.93%Color and Shape:White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicideMolecular weight:438.76Dimethoate
CAS:Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.Formula:C5H12NO3PS2Purity:99.74% - 99.91%Color and Shape:White Crystalline SolidMolecular weight:229.26Antitumor agent-56
CAS:Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.Formula:C28H28N2O10SColor and Shape:SolidMolecular weight:584.59UCB-6876
CAS:UCB-6876 inhibits TNF signaling, stabilizes trimer asymmetry, shows concentration response, and is selective for TNFR1.Formula:C17H18N2OColor and Shape:SolidMolecular weight:266.34BMS-242
CAS:BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.Formula:C28H35NO4Purity:98%Color and Shape:SolidMolecular weight:449.58PD-1/PD-L1-IN 5
CAS:PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).Formula:C22H18N4O3SColor and Shape:SolidMolecular weight:418.47Isodispar B
CAS:Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.Formula:C20H18O5Color and Shape:SolidMolecular weight:338.35ABD56
CAS:ABD56 inhibits osteoclast formation and activity in vitro and in vivo.Formula:C17H18O3Color and Shape:SolidMolecular weight:270.32PI3K-IN-34
CAS:PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.Formula:C23H22N6O3Color and Shape:SolidMolecular weight:430.46EGFR/HER2/TS-IN-1
CAS:EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.Formula:C24H15N5O4S2Color and Shape:SolidMolecular weight:501.54Bcl-2/Mcl-1-IN-1
CAS:Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.Formula:C28H23NO3Color and Shape:SolidMolecular weight:421.49Verticillin A
CAS:Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.Formula:C30H28N6O6S4Purity:98%Color and Shape:SolidMolecular weight:696.84CN128 hydrochloride
CAS:CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.
Formula:C15H18ClNO3Color and Shape:SolidMolecular weight:295.76SK-7041
CAS:SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.Formula:C19H21N3O3Purity:98%Color and Shape:SolidMolecular weight:339.39p-DDAP
CAS:p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.Formula:C18H31NOPurity:98%Color and Shape:SolidMolecular weight:277.44HDAC6-IN-4
CAS:HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.Formula:C30H38N2O5Color and Shape:SolidMolecular weight:506.63VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.Formula:C26H21ClF3N5O3S2Color and Shape:SolidMolecular weight:608.05CDK9-IN-18
CAS:CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.Formula:C27H20N8OColor and Shape:SolidMolecular weight:472.5MMP-9-IN-5
CAS:MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.Formula:C27H20IN3O4Color and Shape:SolidMolecular weight:577.37Tigilanol tiglate
CAS:Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.Formula:C30H42O10Purity:98%Color and Shape:SolidMolecular weight:562.65PSB 0474
CAS:P2Y6 receptor agonistFormula:C17H20N2O13P2Purity:98%Color and Shape:SolidMolecular weight:522.292'-Deoxyadenosine
CAS:2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.Formula:C10H13N5O3Purity:99.71%Color and Shape:SolidMolecular weight:251.24MEK-IN-5
CAS:MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.Formula:C29H27FN4O10S2Color and Shape:SolidMolecular weight:674.67YLT-11
YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.Formula:C24H24N6OColor and Shape:SolidMolecular weight:412.49MM-102
CAS:MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.Formula:C35H49F2N7O4Purity:98.77% - 99.99%Color and Shape:SolidMolecular weight:669.8Ref: TM-T6333
1mg37.00€2mg49.00€5mg100.00€10mg165.00€25mg334.00€50mg515.00€100mg737.00€1mL*10mM (DMSO)147.00€SPRC
CAS:"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."Formula:C6H9NO2SPurity:98%Color and Shape:SolidMolecular weight:159.21EGFR-IN-52
CAS:EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44cRIPGBM
CAS:cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.Formula:C26H20FN2O2Purity:98%Color and Shape:SolidMolecular weight:411.45DPBQ
CAS:DPBQ (ZINC1620467) is a p53 activator.Formula:C24H14N2O2Purity:98.08%Color and Shape:SolidMolecular weight:362.38Ref: TM-T11092
1mg100.00€2mg149.00€5mg245.00€10mg354.00€25mg532.00€50mg735.00€100mg982.00€500mgTo inquireGKK1032B
CAS:GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.Formula:C32H39NO4Color and Shape:SolidMolecular weight:501.66Nec-3a
CAS:Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.Formula:C21H18F4N2O4Color and Shape:SolidMolecular weight:438.37HBV-IN-23
CAS:HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.Formula:C25H27N3O3SColor and Shape:SolidMolecular weight:449.57Anti-melanoma agent 1
CAS:Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.Formula:C28H28N2O2Color and Shape:SolidMolecular weight:424.53UCD38B HCl
CAS:UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.Formula:C15H17Cl2N7O3Purity:98%Color and Shape:SolidMolecular weight:414.25BLM-IN-1
CAS:BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.Formula:C28H35FN4OColor and Shape:SolidMolecular weight:462.62,3-DCPE
CAS:Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).Formula:C11H15Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:264.15ABI-231 HCl
CAS:ABI-231: Oral tubulin inhibitor, IC50=5.2 nM for melanoma/prostate cancer, in clinical trials for prostate cancer, effective in vivo.Formula:C21H20ClN3O4Color and Shape:SolidMolecular weight:413.85RO27-3225 TFA
CAS:RO27-3225, a MC4R agonist (EC50=1nM), may treat obesity and brain damage, also acts on MC1R, and helps in hemorrhagic shock.Formula:C41H53F3N12O8Color and Shape:SolidMolecular weight:898.9462Apoptosis inducer 6
CAS:Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.Formula:C27H26N4O3SColor and Shape:SolidMolecular weight:486.59PERK-IN-3
CAS:PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).Formula:C22H16F2N4O2Purity:98%Color and Shape:SolidMolecular weight:406.38MCL-1/BCL-2-IN-3
CAS:MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.Formula:C27H25BrN2O5SColor and Shape:SolidMolecular weight:569.47MDM2-IN-1
CAS:MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.Formula:C23H21Cl2FN2O3Color and Shape:SolidMolecular weight:463.33ASK1-IN-3
CAS:ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.Formula:C18H18N8O2Color and Shape:SolidMolecular weight:378.39GZD856
CAS:GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:532.56Ki23057
CAS:Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.Formula:C30H35N3O4Color and Shape:SolidMolecular weight:501.62CMLD012612
CAS:CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).Formula:C31H33N3O7Purity:98%Color and Shape:SolidMolecular weight:559.61Darinaparsin
CAS:Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.Formula:C12H22AsN3O6SColor and Shape:SolidMolecular weight:411.31RIP1 kinase inhibitor 5
CAS:RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) inFormula:C13H17F2NO2Purity:98%Color and Shape:SolidMolecular weight:257.28Tubulin polymerization-IN-26
CAS:Tubulin-IN-26 blocks microtubule formation at colchicine site; IC50 4.64μM; may help in lung cancer study.Formula:C25H23N3O2Color and Shape:SolidMolecular weight:397.47CHMFL-ABL/KIT-155
CAS:CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).Formula:C33H38F3N5O3Purity:98%Color and Shape:SolidMolecular weight:609.68NSC10010 hydrochloride
CAS:NSC10010 inhibits gammaherpesvirus B-lymphomas by activating NF-κB and c-Myc pathways.Formula:C31H42Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:573.60IZTZ-1
CAS:IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.Formula:C32H35N7SColor and Shape:SolidMolecular weight:549.73PD-1/PD-L1-IN 6
CAS:Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.Formula:C25H26N2O3Color and Shape:SolidMolecular weight:402.49MDH1-IN-2
CAS:MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.Formula:C25H33NO5Purity:99.21%Color and Shape:SolidMolecular weight:427.53AKCI
CAS:AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.Formula:C19H27N7OPurity:98%Color and Shape:SolidMolecular weight:369.46Setafrastat
CAS:Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor.Formula:C25H33F2N3O4Color and Shape:SolidMolecular weight:477.54XMD15-44
CAS:XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Formula:C29H29F3N4OColor and Shape:SolidMolecular weight:506.56FL3
CAS:FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.Formula:C25H23BrO5Color and Shape:SolidMolecular weight:483.35F5446
CAS:F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Formula:C26H17ClN2O8SPurity:98.56%Color and Shape:SolidMolecular weight:552.94TSI-13-57
CAS:TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization ,inhibits LPS-induced TNF-α (IC50 = 6.73 mM).Formula:C28H29N3O3Purity:99.63%Color and Shape:SolidMolecular weight:455.55Arecaidine propargyl ester (hydrobromide)
CAS:Arecaidine propargyl ester: selective M2 muscarinic receptor agonist, induces guinea pig atrium contraction, lowers cat blood pressure, toxic to flies.Formula:C10H14BrNO2Color and Shape:SolidMolecular weight:260.13HS56
CAS:HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.Formula:C13H8ClN5OSColor and Shape:SolidMolecular weight:317.75Melflufen
CAS:Melflufen, a dipeptide prodrug of Melphalan, is an alkylating agent with strong antitumor activity in MM, causing DNA damage and cytotoxicity.Formula:C24H30Cl2FN3O3Purity:97.056%Molecular weight:498.42BPTQ
CAS:BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.Formula:C17H16N4SPurity:98%Color and Shape:SolidMolecular weight:308.4MG-115
CAS:MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.Formula:C25H39N3O5Purity:97.10%Color and Shape:White PowderMolecular weight:461.59Ivaltinostat
CAS:CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.Formula:C24H33N3O4Purity:98%Color and Shape:SolidMolecular weight:427.54CSRM617
CAS:CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.Formula:C10H13N3O5Purity:98%Color and Shape:SolidMolecular weight:255.23Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.Formula:C27H18F5N3O5SPurity:98%Color and Shape:SolidMolecular weight:591.51NSC745885
CAS:NSC745885, Antitumor agent, downregulates EZH2 via proteasomal degradation, toxic to drug-resistant cancer lines, for bladder and oral cancer.Formula:C14H6N2O2SPurity:98%Color and Shape:SolidMolecular weight:266.27bpV(phen)
CAS:bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).Formula:C12H8KN2O5VPurity:98%Color and Shape:SolidMolecular weight:350.24MI-192
CAS:MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.Formula:C24H21N3O2Color and Shape:SolidMolecular weight:383.44Estramustine phosphate
CAS:Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.Formula:C23H32Cl2NO6PColor and Shape:SolidMolecular weight:520.38Nutlin-1
CAS:Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.Formula:C32H34Cl2N4O4Color and Shape:SolidMolecular weight:609.54PD-1/PD-L1-IN-NP19
CAS:PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.Formula:C33H31ClN2O4Purity:96.70%Color and Shape:SolidMolecular weight:555.06PD-1-IN-22
CAS:PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).Formula:C25H25N5O4Purity:99.51%Color and Shape:SolidMolecular weight:459.5Ref: TM-T12379
1mg109.00€2mg163.00€5mg243.00€10mg355.00€25mg532.00€50mg750.00€100mg1,009.00€500mg2,035.00€1mL*10mM (DMSO)284.00€HDAC1/2 and CDK2-IN-1
CAS:Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.Formula:C26H22ClN7OColor and Shape:SolidMolecular weight:483.95BN201
CAS:BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.Formula:C25H38FN5O4Purity:99.42% - 99.42%Color and Shape:SolidMolecular weight:491.6MPT0B392
CAS:MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.Formula:C19H20N2O6SColor and Shape:SolidMolecular weight:404.44HDACs/mTOR Inhibitor 1
CAS:HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,Formula:C28H38N8O5Color and Shape:SolidMolecular weight:566.65ACA-28
CAS:ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.Formula:C17H16O6Purity:98.73%Color and Shape:SolidMolecular weight:316.31Ref: TM-T60821
1mg101.00€5mg241.00€10mg382.00€25mg754.00€50mg1,238.00€100mg1,839.00€200mg2,489.00€1mL*10mM (DMSO)265.00€HL271
CAS:HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.Formula:C13H17ClF3N5OPurity:98%Color and Shape:SolidMolecular weight:351.76ML132
CAS:ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).Formula:C22H28ClN5O5Color and Shape:SolidMolecular weight:477.94pan-HER-IN-1
CAS:Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.Formula:C19H14BrN5OColor and Shape:SolidMolecular weight:408.25Jolkinolide B
CAS:Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.
Formula:C20H26O4Purity:99.39% - 99.7%Color and Shape:SolidMolecular weight:330.42MYRA-A
CAS:MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.Formula:C19H20N2O4Purity:98%Color and Shape:SolidMolecular weight:340.37BTK-IN-9
CAS:BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.Formula:C25H19N7O4Color and Shape:SolidMolecular weight:481.46Telomerase-IN-4
CAS:Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].Formula:C21H18N4OS2Purity:98%Color and Shape:SolidMolecular weight:406.52Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purity:98%Color and Shape:SolidMolecular weight:578.58Telomerase-IN-5
CAS:Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].Formula:C22H20N4OS2Purity:98%Color and Shape:SolidMolecular weight:420.55Tubulin/HDAC-IN-1
CAS:Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.Formula:C21H18N4O3Color and Shape:SolidMolecular weight:374.39BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Formula:C20H21N5OPurity:99.71%Color and Shape:SolidMolecular weight:347.41Mutant p53 modulator-1
CAS:Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.Formula:C27H32F4N8O2Color and Shape:SolidMolecular weight:576.59
