Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formula:C24H29N5O2Purity:97.67% - 98.81%Color and Shape:SolidMolecular weight:419.52Ref: TM-T62209
1mg63.00€5mg137.00€10mg207.00€25mg408.00€50mg655.00€100mg1,009.00€200mg1,359.00€1mL*10mM (DMSO)161.00€DX3-213B
CAS:DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.Formula:C20H28F2N2O5S2Purity:99.85%Color and Shape:SolidMolecular weight:478.57Ref: TM-T63136
1mg81.00€5mg170.00€10mg274.00€25mg588.00€50mg852.00€100mg1,159.00€1mL*10mM (DMSO)180.00€Antifolate C2
CAS:Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.Formula:C19H21N5O6SPurity:99.57%Color and Shape:SolidMolecular weight:447.46MMRi64
CAS:MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3Lanperisone HCl
CAS:Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.Formula:C15H19ClF3NOPurity:98.67% - >99.99%Color and Shape:SolidMolecular weight:321.77EB1
CAS:EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.Formula:C18H14N4Purity:99.82%Color and Shape:SolidMolecular weight:286.33Ref: TM-T73582
1g3,142.00€1mg71.00€5mg152.00€10mg215.00€25mg355.00€50mg533.00€100mg762.00€500mg2,115.00€Alethine
CAS:Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.Formula:C10H22N4O2S2Purity:99.78%Color and Shape:SolidMolecular weight:294.44Prinomastat
CAS:Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.Formula:C18H21N3O5S2Purity:99.23%Color and Shape:SolidMolecular weight:423.51Ref: TM-T12539L
1mg70.00€2mg111.00€5mg226.00€10mg409.00€25mg660.00€50mg888.00€100mg1,224.00€200mg1,648.00€CCT020312
CAS:CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.Formula:C31H30Br2N4O2Purity:98.63%Color and Shape:SolidMolecular weight:650.4Ref: TM-T14902
1mg58.00€5mg133.00€10mg227.00€25mg386.00€50mg572.00€100mg795.00€500mg1,648.00€1mL*10mM (DMSO)178.00€cRIPGBM chloride
CAS:cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.Formula:C26H20ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:446.9SCFSkp2-IN-2
CAS:SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.
Formula:C17H20N4O2Purity:99.86%Color and Shape:SolidMolecular weight:312.37Ciglitazone
CAS:Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.Formula:C18H23NO3SPurity:98.23% - 99.84%Color and Shape:White Cyrstalline SolidMolecular weight:333.45KR-33493
CAS:KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.Formula:C20H18BrN3O3SPurity:99.96%Color and Shape:SolidMolecular weight:460.34Etomoxir
CAS:Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!Formula:C17H23ClO4Purity:98% - 99.39%Color and Shape:SolidMolecular weight:326.82PARP/PI3K-IN-1
CAS:PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Formula:C33H28F4N8O3Purity:99.59%Color and Shape:SolidMolecular weight:660.62XX-650-23
CAS:XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).Formula:C18H12N2O2Purity:97.01%Color and Shape:SolidMolecular weight:288.3Ref: TM-T24212
1mg44.00€5mg96.00€10mg138.00€25mg268.00€50mg447.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)92.00€BC 11 hydrobromide
CAS:The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.Formula:C8H12BBrN2O2SPurity:98.07%Color and Shape:SolidMolecular weight:290.97Anticancer agent 110
CAS:Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cellsFormula:C18H13FN6OSPurity:98%Color and Shape:SolidMolecular weight:380.4GS-9191
CAS:GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , whichFormula:C37H51N8O6PPurity:98.01 - 99.28%Color and Shape:SolidMolecular weight:734.82CDK9-IN-7
CAS:CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.Formula:C29H37N7O2SPurity:98.08%Color and Shape:SolidMolecular weight:547.71Ref: TM-T10745
1mg90.00€5mg208.00€10mg304.00€25mg457.00€50mg630.00€100mg845.00€200mg1,121.00€1mL*10mM (DMSO)229.00€CBS9106
CAS:CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.Formula:C18H21ClF3N3O3Purity:98.98%Color and Shape:SolidMolecular weight:419.83Exisulind
CAS:Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.Formula:C20H17FO4SPurity:97.94%Color and Shape:SolidMolecular weight:372.41Deferitazole
CAS:Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Formula:C18H25NO7SPurity:99.48%Color and Shape:SolidMolecular weight:399.46DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formula:C16H8ClF6N3OPurity:99.63%Color and Shape:SolidMolecular weight:407.7N6-Cyclopentyladenosine
CAS:N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's ofFormula:C15H21N5O4Purity:99.95%Color and Shape:SolidMolecular weight:335.36RS1-PDK1 inhibitor
CAS:RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.Formula:C15H9ClN2O2S3Purity:97.65%Color and Shape:SolidMolecular weight:380.89Sarmustine
CAS:SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.
Formula:C6H11ClN4O3Purity:98.29% - 99.71%Color and Shape:SolidMolecular weight:222.63NecroX-7
CAS:NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.Formula:C24H29N3O3SPurity:98.22%Color and Shape:SolidMolecular weight:439.57HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Formula:C20H24N2O6Purity:97.35% - 98.58%Color and Shape:SolidMolecular weight:388.41C6 Ceramide
CAS:C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.Formula:C24H47NO3Purity:99.67% - 99.73%Color and Shape:SolidMolecular weight:397.63Mepazine
CAS:Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.Formula:C19H22N2SPurity:99.88% - 99.92%Color and Shape:SolidMolecular weight:310.46Ref: TM-T16040
10mg39.00€25mg60.00€50mg93.00€100mg116.00€200mg177.00€500mgTo inquire1mL*10mM (DMSO)35.00€Tubulin inhibitor 11
CAS:Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.Formula:C22H23N3O3SPurity:99.93%Color and Shape:SoildMolecular weight:409.5Ref: TM-T67935
1mg35.00€5mg80.00€10mg116.00€25mg259.00€50mg383.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)96.00€A09-003
CAS:A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.Formula:C23H26N4OPurity:99.61%Color and Shape:SolidMolecular weight:374.48SPD304 dihydrochloride
CAS:SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
Formula:C32H34Cl2F3N3O2Purity:99.25%Color and Shape:SolidMolecular weight:620.53RO-5963
CAS:RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).Formula:C24H21ClF2N4O5Purity:99.28%Color and Shape:SolidMolecular weight:518.9Ref: TM-T16771
1mg66.00€5mg187.00€10mg269.00€25mg411.00€50mg532.00€100mg740.00€200mg982.00€1mL*10mM (DMSO)212.00€CMLD-2
CAS:CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.Formula:C31H31NO6Purity:99.99%Color and Shape:SolidMolecular weight:513.58Ref: TM-T36493
1mg92.00€5mg222.00€10mg371.00€25mg608.00€50mg848.00€100mg1,144.00€500mg2,277.00€1mL*10mM (DMSO)245.00€EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formula:C29H35N9O2SPurity:99.93%Color and Shape:SolidMolecular weight:573.71Minodronic acid
CAS:Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.Formula:C9H12N2O7P2Purity:99.39%Color and Shape:SolidMolecular weight:322.15AQ4
CAS:AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Formula:C22H28N4O4Purity:96.28% - 97.15%Color and Shape:SolidMolecular weight:412.48iCRT-5
CAS:iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.Formula:C16H17NO5S2Purity:99.68%Color and Shape:SolidMolecular weight:367.44SLMP53-1
CAS:SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migrationFormula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37Ref: TM-T60839
1mg119.00€5mg281.00€10mg462.00€25mg888.00€50mg1,485.00€100mg2,385.00€1mL*10mM (DMSO)34.00€OR-1896
CAS:OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.Formula:C13H15N3O2Purity:99.33%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12315
1mg89.00€5mg187.00€10mg309.00€25mg622.00€50mg982.00€100mg1,333.00€200mg1,783.00€1mL*10mM (DMSO)207.00€Triparanol
CAS:Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1Formula:C27H32ClNO2Purity:99.72%Color and Shape:SolidMolecular weight:438Ref: TM-T26296
1mg284.00€5mg645.00€10mg867.00€25mg1,283.00€50mg1,700.00€100mg2,347.00€1mL*10mM (DMSO)690.00€VAS 3947
CAS:VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.Formula:C14H10N6OSPurity:99.25%Color and Shape:SolidMolecular weight:310.33Ref: TM-T29097
1mg46.00€5mg92.00€10mg166.00€25mg279.00€50mg403.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)100.00€Sabizabulin
CAS:Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Formula:C21H19N3O4Purity:98.10% - 99.79%Color and Shape:SolidMolecular weight:377.39Ref: TM-T17228
1mg75.00€2mg99.00€5mg164.00€10mg255.00€25mg487.00€50mg803.00€100mg1,324.00€200mg1,783.00€Miclxin
CAS:Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potentFormula:C26H27N5O2Purity:99.17% - 99.99%Color and Shape:SolidMolecular weight:441.52Ref: TM-T73415
1mg60.00€5mg133.00€10mg182.00€25mg306.00€50mg427.00€100mg587.00€200mg792.00€1mL*10mM (DMSO)147.00€1G244
CAS:1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.Formula:C29H30F2N4O2Purity:99.14%Color and Shape:SolidMolecular weight:504.57T025
CAS:T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Formula:C21H18N8Purity:99.20%Color and Shape:SolidMolecular weight:382.42Ref: TM-T13058
1mg136.00€5mg334.00€10mg500.00€25mg807.00€50mg1,099.00€100mg1,485.00€500mg2,962.00€1mL*10mM (DMSO)358.00€AOH1160
CAS:AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formula:C25H20N2O3Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:396.44SB 699551 dihydrochloride
CAS:SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.Formula:C34H47Cl2N3OPurity:99.83%Color and Shape:SolidMolecular weight:584.66Ref: TM-T23325
1mg50.00€5mg105.00€10mg170.00€25mg295.00€50mg424.00€100mg583.00€1mL*10mM (DMSO)142.00€RET-IN-23
CAS:RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.Formula:C28H28FN11Purity:97.46%Color and Shape:SolidMolecular weight:537.59W146
CAS:W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.Formula:C16H27N2O4PPurity:99.37%Color and Shape:SolidMolecular weight:342.37UC-112
CAS:UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Formula:C22H24N2O2Purity:99.54%Color and Shape:SolidMolecular weight:348.44Ref: TM-T17195
1mg34.00€2mg44.00€5mg70.00€10mg99.00€25mg202.00€50mg311.00€100mg445.00€500mgTo inquire1mL*10mM (DMSO)78.00€K-8012
CAS:K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.Formula:C23H23FN4Purity:99.72%Color and Shape:SolidMolecular weight:374.45Ref: TM-T24240
1mg109.00€5mg241.00€10mg355.00€25mg532.00€50mg745.00€100mg1,018.00€500mg2,043.00€1mL*10mM (DMSO)253.00€Stemazole
CAS:Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.Formula:C9H9N5OS2Purity:98.59%Color and Shape:SolidMolecular weight:267.33Ref: TM-T28866
1mg52.00€5mg101.00€10mg164.00€25mg334.00€50mg532.00€100mg858.00€200mg1,149.00€1mL*10mM (DMSO)95.00€CSN5i-3
CAS:CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.Formula:C28H29F2N5O2Purity:99.56% - >99.99%Color and Shape:SolidMolecular weight:505.56Ref: TM-T10895
1mg340.00€5mg732.00€10mg1,108.00€25mg1,648.00€50mg2,223.00€100mg2,997.00€1mL*10mM (DMSO)797.00€SYM 2081
CAS:SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.Formula:C6H11NO4Purity:99.63%Color and Shape:SolidMolecular weight:161.16TC-DAPK 6
CAS:TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.Formula:C17H12N2O2Purity:98.73%Color and Shape:SolidMolecular weight:276.29RIPK3-IN-1
CAS:RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.Formula:C29H25FN4O4Purity:98.27%Color and Shape:SolidMolecular weight:512.53Benitrobenrazide
CAS:Benitrobenrazide (Hexokinase 2 inhibitor 1) is a novel orally available hexokinase 2 (HK2) inhibitor with anticancer and antitumor activity for cancer research.Formula:C14H11N3O6Purity:96.87%Color and Shape:SolidMolecular weight:317.25UCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Formula:C22H21N3OPurity:98.76%Color and Shape:SolidMolecular weight:343.42P505-15 Acetate
CAS:P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.
Formula:C21H27N9O3Purity:99.99%Color and Shape:SolidMolecular weight:453.5ZDLD20
CAS:ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.Formula:C22H22N6OPurity:98.59%Color and Shape:SolidMolecular weight:386.45HS38
CAS:HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.Formula:C14H12ClN5O2SPurity:98.19%Color and Shape:SolidMolecular weight:349.8TT01001
CAS:TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.Formula:C15H19Cl2N3O2SPurity:99.93%Color and Shape:SolidMolecular weight:376.3Erastin2
CAS:Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.
Formula:C36H35ClN4O4Purity:99.63%Color and Shape:SolidMolecular weight:623.14Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Formula:C22H27Cl2N7O2SPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:524.47UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purity:99.80%Color and Shape:SolidMolecular weight:515.69Utreloxastat
CAS:Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis .Formula:C18H28O2Purity:99.95%Color and Shape:SolidMolecular weight:276.41Ref: TM-T60507
1mg96.00€5mg205.00€10mg295.00€25mg505.00€50mg745.00€100mg1,305.00€200mg1,755.00€1mL*10mM (DMSO)224.00€HBDDE
CAS:HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.Formula:C16H18O8Purity:99.99%Color and Shape:SolidMolecular weight:338.31RET-IN-24
CAS:RET-IN-24 (Compound 26) is a selective inhibitor of RET tyrosine kinase, demonstrating antitumor activity [1].Formula:C27H26F2N8OColor and Shape:SolidMolecular weight:516.55PRMT6-IN-3
CAS:PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.Formula:C19H26N4O2SPurity:98.12%Color and Shape:SolidMolecular weight:374.5RIP2 kinase inhibitor 2
CAS:RIP2 kinase inhibitor 2 is a receptor-interacting protein-2 kinase inhibitor.Formula:C21H28N4O4SPurity:98%Color and Shape:SolidMolecular weight:432.54AM-8735
CAS:AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).Formula:C27H31Cl2NO6SPurity:98%Color and Shape:SolidMolecular weight:568.51M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purity:98%Color and Shape:SolidMolecular weight:375.42PD-1/PD-L1-IN-33
CAS:PD-1/PD-L1-IN-33 (Compound N11), a PD-1/PD-L1 inhibitor, effectively impedes the interaction between PD-1 and PD-L1 with an IC50 of 6.3 nM.Formula:C26H27N5OPurity:98%Color and Shape:SolidMolecular weight:425.53GCN2-IN-6
CAS:GCN2-IN-6: Potent, oral GCN2/PERK inhibitor; IC50s - GCN2: 1.8 nM (enzymatic), 9.3 nM (cellular); PERK: 0.26 nM (enzymatic), 230 nM (cellular).Formula:C19H12Cl2F2N4O3SPurity:95.04% - 98%Color and Shape:SolidMolecular weight:485.29SWS1
CAS:SWS1, a d-(+)-biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating antiFormula:C47H53ClN6O5SPurity:98%Color and Shape:SolidMolecular weight:849.48iMAC2 hydrochloride
CAS:iMAC2 hydrochloride, a potent inhibitor of the mitochondrial apoptosis-induced channel (MAC), demonstrates an IC50 of 28 nM and an LD50 of 15000 nM. It exhibits an anti-apoptotic effect by blocking the release of cytochrome c [1].Formula:C19H22Br2Cl2FN3Color and Shape:SolidMolecular weight:542.11c-Met/HDAC-IN-3
CAS:c-Met/HDAC-IN-3: dual inhibitor; IC50: c-Met 12.5 nM, HDAC1 26.97 nM; induces apoptosis, G2/M arrest.Formula:C34H35FN4O7Color and Shape:SolidMolecular weight:630.66TL02-59
CAS:TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Formula:C32H34F3N5O4Purity:98.77%Color and Shape:SolidMolecular weight:609.64Ref: TM-T13186
1mg49.00€2mg62.00€5mg93.00€10mg133.00€25mg260.00€50mg401.00€100mg557.00€200mg790.00€1mL*10mM (DMSO)111.00€Anticancer agent 118
CAS:Anticancer Agent 118, an N‑acylated ciprofloxacin derivative, exhibits antibacterial efficacy against Gram-positive strains and antiproliferative effects onFormula:C19H19ClFN3O4Color and Shape:SolidMolecular weight:407.82Deoxynybomycin
CAS:Deoxynybomycin, a selective anti-tumor agent, inhibits topoisomerase I and induces apoptosis.Formula:C16H14N2O3Purity:98%Color and Shape:SolidMolecular weight:282.29Prostaglandin A1
CAS:Prostaglandin A1, a dehydration derivative of Prostaglandin E1, demonstrates inhibitory effects on tumor growth, inflammation, virus replication, platelet aggregation, and excitotoxin-induced neuron apoptosis [1].Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472ASC-69
CAS:ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].Formula:C19H19N7Purity:98%Color and Shape:SolidMolecular weight:345.4RIP1 kinase inhibitor 4
CAS:RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46PD-1/PD-L1-IN-26
CAS:PD-1/PD-L1-IN-26 is a strong inhibitor with IC50 of 0.0380 μM that may boost immune response in cancer by aiding CD4+ T cell entry to tumors.Formula:C43H52N4O8Purity:98%Color and Shape:SolidMolecular weight:752.89RIPK2-IN-3
CAS:RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.Formula:C25H22N4O2Purity:99.57%Color and Shape:SolidMolecular weight:410.471-Stearoyl-2-Adrenoyl-sn-glycero-3-PC
CAS:1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) acts as a cyclin-dependent kinase (CDK) inhibitor, promoting apoptosis and restricting the proliferation of various cancer cell lines [1].Formula:C48H88NO8PColor and Shape:SolidMolecular weight:838.19TM5441 sodium
CAS:TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].Formula:C21H16ClN2NaO6Color and Shape:SolidMolecular weight:450.8GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Formula:C20H25N5O4SColor and Shape:SolidMolecular weight:431.51Nedometinib
CAS:Nedometinib (NFX-179) is a MEK1 inhibitor with anticancer and antitumor activities, which can be used to study malignant tumors.Formula:C17H16FIN4O3Purity:99.18%Color and Shape:SolidMolecular weight:470.24Ref: TM-T78209
1mg66.00€5mg145.00€10mg215.00€25mg353.00€50mg537.00€100mg708.00€1mL*10mM (DMSO)150.00€Bcl-2-IN-13
CAS:Bcl-2-IN-13 is a potent inhibitor of Bcl-2, exhibiting an IC50 of 17 nM, and holds potential for use in cancer research [1].Formula:C42H44ClN7O6S3Color and Shape:SolidMolecular weight:874.49Mcl-1 inhibitor 13
CAS:Mcl-1 Inhibitor 13 (Example 9), with a Ki of 8.2 nM, serves as an MCL-1 inhibitor suitable for cancer research [1].Formula:C47H45ClFN7O6Color and Shape:SolidMolecular weight:858.35MAO-B-IN-26
CAS:MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Formula:C17H12BrNOPurity:98%Color and Shape:SolidMolecular weight:326.19NLRP3 agonist 1
CAS:Vatalanib hydrochloride (PTK787 hydrochloride) is a VEGF inhibitor that reduces the number and area of Aβ plaques in the cortex of 5xFAD mice.Formula:C15H16N6Purity:99.01%Color and Shape:SolidMolecular weight:280.33DX3-235
CAS:DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor on mitochondrial complex I function in galactose-containing media, resulting in reduced ATP.Formula:C26H39N5O6S2Purity:99.97%Color and Shape:SolidMolecular weight:581.75HJC0152 free base
CAS:HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograftFormula:C15H13Cl2N3O4Purity:98%Color and Shape:SolidMolecular weight:370.19RUNX-IN-1
CAS:RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with theirFormula:C71H88Cl2N24O11Purity:98%Color and Shape:SolidMolecular weight:1524.52RET-IN-17
CAS:RET-IN-17 inhibits RET kinase; may help in IBS pain and RET-activated cancers.Formula:C27H28F4N4O4Color and Shape:SolidMolecular weight:548.53
