Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5599 products of "Apoptosis"
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SZUH280
CAS:<p>SZUH280 is a potent, selective PROTAC (proteolysis targeting chimera) HDAC8 (histone deacetylase 8) degrader, demonstrating a DC50 of 0.58 μM in A549 cells.</p>Formula:C36H34N8O8Color and Shape:SolidMolecular weight:706.7Asunercept
CAS:<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Color and Shape:LiquidCalcimycin hemimagnesium
CAS:<p>Calcimycin hemimagnesium is an antibiotic, ionophore, and ATPase inhibitor that boosts intracellular Ca2+, causing cell death and apoptosis.</p>Formula:C58H72MgN6O12Color and Shape:SolidMolecular weight:1069.53Thalidomide-NH-PEG4-COOH
CAS:<p>Thalidomide-NH-PEG4-COOH is a E3 ligase ligand-linker for synthesizing the selective degrader dCBP-1 targeting p300/CBP.</p>Formula:C24H31N3O10Color and Shape:SolidMolecular weight:521.523Manelimab
CAS:<p>Manelimab is a monoclonal antibody that inhibits programmed death-ligand 1 ( PD-L1 ) [1] .</p>Color and Shape:LiquidHJC0416 hydrochloride
CAS:<p>HJC0416 hydrochloride: potent oral STAT3 inhibitor, better anticancer effects than Stattic, promising for breast cancer research.</p>Formula:C18H18Cl2N2O4SColor and Shape:SolidMolecular weight:429.31FLT3-IN-21
<p>FLT3-IN-21 (compound LC-3), a potent FLT3 inhibitor with an IC50 value of 8.4 nM, induces apoptosis and arrests the cell cycle in the G1 phase.</p>Formula:C20H22FN5O2Color and Shape:SolidMolecular weight:383.42BM-1197
CAS:<p>BM-1197, a highly potent and specific dual inhibitor of Bcl-2 and Bcl-xL, effectively targets these proteins with IC50 values of 3.5 nM and 5.2 nM for Bcl-2 and</p>Formula:C53H59ClF4N6O7S4Color and Shape:SolidMolecular weight:1131.77ReACp53
<p>ReACp53 inhibits amyloid formation, restores p53 in cancer cells and HGSOC-derived organoids.</p>Formula:C108H206N52O24Purity:98%Color and Shape:SolidMolecular weight:2617.13PROTAC Bcl-xL degrader-1
<p>PROTAC Bcl-xL degrader-1 targets Bcl-xL & IAP E3 ligases, degrades Bcl-xL, toxic to human platelets & MyLa 1929 (IC50: 62 nM, 8.5 μM).</p>Formula:C76H96ClF3N10O11S3Color and Shape:SolidMolecular weight:1514.28VB-85247
<p>VB-85247 is a STING agonist that, by activating the STING pathway, induces the upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as the maturation and activation of dendritic cells. It can lead to the regression of tumors within the bladder and is applicable in bladder cancer research.</p>Color and Shape:Odour SolidNargenicin
CAS:<p>Nargenicin: a macrolide antibiotic effective against S. aureus, MRSA, M. luteus; inhibits bacterial DnaE and reduces inflammation and leukemia cell growth.</p>Formula:C28H37NO8Color and Shape:SolidMolecular weight:515.6Thalidomide-PEG4-NH2 hydrochloride
CAS:<p>Thalidomide-PEG4-NH2 HCl, a cereblon ligand-linker for PROTAC.</p>Formula:C21H28ClN3O8Color and Shape:SolidMolecular weight:485.92Thalidomide-O-C8-NH2 hydrochloride
CAS:<p>Thalidomide-derived cereblon ligand with PROTAC linker as an E3 ligase ligand-linker conjugate, in hydrochloride form.</p>Formula:C21H28ClN3O5Color and Shape:SolidMolecular weight:437.92Relfovetmab
CAS:<p>Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .</p>Color and Shape:LiquidSatratoxin G
CAS:<p>Satratoxin G, from Stachybotrys chartarum, triggers apoptosis in nasal and brain OSNs.</p>Formula:C29H36O10Color and Shape:SolidMolecular weight:544.597Thalidomide-PEG2-C2-NH2
CAS:<p>Thalidomide-O-amido-PEG3-C2-NH2 is a cereblon ligand-linked E3 ligase used in PROTAC with a 2-unit PEG.</p>Formula:C19H24N4O6Purity:98%Color and Shape:SolidMolecular weight:404.42Sudubrilimab
<p>Sudubrilimab (HS636) is an IgG1-κ monoclonal antibody targeting PDL1, fused with TGFBR2-ECD to block PD-1/PDL1 and TGF-β in tumors.</p>Color and Shape:Odour LiquidMitoEbselen-2 chloride
CAS:<p>MitoEbselen-2 mitigates radiation, cuts lipid hydroperoxides, blocks cell death, and boosts survival in irradiated mice.</p>Formula:C35H30ClN2O2PSeColor and Shape:SolidMolecular weight:656.01DS-5272
CAS:<p>DS-5272 is a potent and orally active inhibitor of p53-MDM2 interaction.</p>Formula:C34H38Cl2F2N6O2SColor and Shape:SolidMolecular weight:703.67
