Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Camptothecin
CAS:<p>Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.</p>Formula:C20H16N2O4Purity:99.52% - 99.88%Color and Shape:Solid PowderMolecular weight:348.35NPB
CAS:<p>NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)</p>Formula:C29H31Cl2N3O2Purity:99.93%Color and Shape:SolidMolecular weight:524.48SAR405838
CAS:<p>MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.</p>Formula:C29H34Cl2FN3O3Purity:98.63%Color and Shape:SolidMolecular weight:562.5Dibenz[a,h]anthracene
CAS:<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Formula:C22H14Purity:99.97%Color and Shape:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Molecular weight:278.35NSC114792
CAS:<p>NSC114792 is a selective JAK3 inhibitor.</p>Formula:C26H32N4O2SPurity:98%Color and Shape:SolidMolecular weight:464.62BPTQ
CAS:<p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>Formula:C17H16N4SPurity:98%Color and Shape:SolidMolecular weight:308.4Tubulin/HDAC-IN-1
CAS:<p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>Formula:C21H18N4O3Color and Shape:SolidMolecular weight:374.39VEGFR-2-IN-19
CAS:<p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>Formula:C21H19N3O2Color and Shape:SolidMolecular weight:345.39STAT3-IN-3
CAS:<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Formula:C27H26BrN3O6SPurity:98%Color and Shape:SolidMolecular weight:600.48EGFR-IN-46
CAS:<p>EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.</p>Formula:C27H32F3N3O3Color and Shape:SolidMolecular weight:503.56SAR125844
CAS:<p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>Formula:C25H23FN8O2S2Purity:98.73%Color and Shape:SolidMolecular weight:550.63MG-115
CAS:<p>MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.</p>Formula:C25H39N3O5Purity:97.12%Color and Shape:White PowderMolecular weight:461.59PCAF-IN-2
CAS:<p>PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.</p>Formula:C10H7F3N6Color and Shape:SolidMolecular weight:268.2SKF1
CAS:<p>SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.</p>Formula:C23H37ClN2O2Purity:98%Color and Shape:SolidMolecular weight:409.01ZC0101
CAS:<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Formula:C17H15N3O2Color and Shape:SolidMolecular weight:293.32Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formula:C29H34N2O15Color and Shape:SolidMolecular weight:650.58SB-218078
CAS:<p>SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).</p>Formula:C24H15N3O3Purity:98%Color and Shape:SolidMolecular weight:393.39BCL6-IN-8c
CAS:<p>BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent</p>Formula:C20H20ClN3O5Color and Shape:SolidMolecular weight:417.84eIF4A3-IN-2
CAS:<p>eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.</p>Formula:C25H19Br2ClN4O2Purity:98%Color and Shape:SolidMolecular weight:602.71iMAC2
CAS:<p>iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting</p>Formula:C19H20Br2FN3Color and Shape:SolidMolecular weight:469.19GL-331
CAS:<p>GL-331, a DNA topoisomerase II inhibitor, is used potentially for the treatment of small cell lung cancer and gastric cancer.</p>Formula:C27H24N2O9Color and Shape:SolidMolecular weight:520.49EAPB 02303
CAS:<p>EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.</p>Formula:C17H14N4O2Color and Shape:SolidMolecular weight:306.32Tubulin polymerization-IN-24
CAS:<p>HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.</p>Formula:C22H16O3Color and Shape:SolidMolecular weight:328.36TP-472
CAS:<p>TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).</p>Formula:C20H19N3O2Purity:98%Color and Shape:SolidMolecular weight:333.38Berubicin HCl
CAS:<p>Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.</p>Formula:C34H36ClNO11Color and Shape:SolidMolecular weight:670.1ASK1-IN-3
CAS:<p>ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.</p>Formula:C18H18N8O2Color and Shape:SolidMolecular weight:378.39GW7845
CAS:<p>GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.</p>Formula:C29H28N2O6Purity:98%Color and Shape:SolidMolecular weight:500.54Anticancer agent 77
CAS:<p>Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.</p>Formula:C25H30BrN7Color and Shape:SolidMolecular weight:508.46MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Formula:C23H21Cl2FN2O3Color and Shape:SolidMolecular weight:463.33YH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Formula:C19H18N2O2Purity:98.06%Color and Shape:SolidMolecular weight:306.36D-Cl-amidine
CAS:<p>D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.</p>Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78HMBPP triammonium
CAS:<p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>Formula:C5H15NO8P2Color and Shape:SolidMolecular weight:279.122ML132
CAS:<p>ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).</p>Formula:C22H28ClN5O5Color and Shape:SolidMolecular weight:477.94Bozepinib
CAS:<p>Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.</p>Formula:C20H14Cl2N6O5SPurity:98%Color and Shape:SolidMolecular weight:521.33PI3Kα-IN-7
CAS:<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Formula:C17H22N8O2SColor and Shape:SolidMolecular weight:402.47B-Raf IN 9
CAS:<p>B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).</p>Formula:C23H20N4OSColor and Shape:SolidMolecular weight:400.5c-Met-IN-9
CAS:<p>c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.</p>Formula:C25H19F2N5O3Color and Shape:SolidMolecular weight:475.45AG-024322
CAS:<p>AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.</p>Formula:C23H20F2N6Purity:98.53%Color and Shape:SolidMolecular weight:418.44ZDLD13
CAS:<p>ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.</p>Formula:C18H14N4OColor and Shape:SolidMolecular weight:302.33Mitoguazone
CAS:<p>Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.</p>Formula:C5H12N8Purity:97.47% - 98%Color and Shape:SolidMolecular weight:184.2DRAK2-IN-1
CAS:<p>Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).</p>Formula:C21H20N4O3Color and Shape:SolidMolecular weight:376.41LSD1-IN-14
CAS:<p>LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.</p>Formula:C21H24FN5Color and Shape:SolidMolecular weight:365.45MIR96-IN-1
CAS:<p>MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.</p>Formula:C33H48N8O2Color and Shape:SolidMolecular weight:588.79TH-Z835
CAS:<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Formula:C30H38N6OPurity:98%Color and Shape:SolidMolecular weight:498.66MR2938
CAS:<p>MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.</p>Formula:C21H24N4O3Color and Shape:SolidMolecular weight:380.44BJE6-106
CAS:<p>BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).</p>Formula:C26H23NO2Color and Shape:SolidMolecular weight:381.472,3-DCPE
CAS:<p>Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).</p>Formula:C11H15Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:264.15(1S,2S)-Bortezomib
CAS:<p>(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.</p>Formula:C19H25BN4O4Purity:99.6%Color and Shape:SolidMolecular weight:384.24CSRM617
CAS:<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Formula:C10H13N3O5Purity:98%Color and Shape:SolidMolecular weight:255.23Ramentaceone
CAS:<p>Ramentaceone is an antineoplastic.</p>Formula:C11H8O3Purity:98%Color and Shape:SolidMolecular weight:188.18Anti-osteoporosis agent-1
CAS:<p>Anti-osteoporosis agent-1 (comp 4aa) is an effective RPA (replication protein A) inhibitor, demonstrating potency with an IC50 value of 18 μM [1].</p>Formula:C20H19ClN2O2Color and Shape:SolidMolecular weight:354.83YLT205
CAS:<p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>Formula:C16H12BrClN4O2S2Purity:98%Color and Shape:SolidMolecular weight:471.78Nafamostat hydrochloride
CAS:<p>Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.</p>Formula:C19H19Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:420.29HSP90-IN-13
CAS:<p>HSP90-IN-13 (5k): potent HSP90 inhibitor, IC50 25.07 nM, targets EGFR/VEGFR-2/Topo-2, blocks MCF-7 G2/M cycle, induces apoptosis.</p>Formula:C26H21N5O3SColor and Shape:SolidMolecular weight:483.54Antitumor agent-45
CAS:<p>Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.</p>Formula:C28H17BrFN5O3Color and Shape:SolidMolecular weight:570.37RIPK3-IN-2
CAS:<p>RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.</p>Formula:C21H16ClN3O2S2Color and Shape:SolidMolecular weight:441.95BLM-IN-1
CAS:<p>BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.</p>Formula:C28H35FN4OColor and Shape:SolidMolecular weight:462.6AMPK activator 11
CAS:<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Formula:C25H20N4O2Purity:98%Color and Shape:SolidMolecular weight:408.45MI-192
CAS:<p>MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.</p>Formula:C24H21N3O2Color and Shape:SolidMolecular weight:383.44UCD38B HCl
CAS:<p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>Formula:C15H17Cl2N7O3Purity:98%Color and Shape:SolidMolecular weight:414.25Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Formula:C28H28N2O2Color and Shape:SolidMolecular weight:424.53DRI-C25441
CAS:<p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>Formula:C31H21N3O6Color and Shape:SolidMolecular weight:531.51DRI-C21041
CAS:<p>DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, demonstrating an inhibitory concentration 50 (IC50) value of 0.31 μM.</p>Formula:C30H21N3O7SColor and Shape:SolidMolecular weight:567.57DX2-201
CAS:<p>DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.</p>Formula:C18H28N2O6S2Color and Shape:SolidMolecular weight:432.55RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Formula:C32H33FN6O4Color and Shape:SolidMolecular weight:584.64IST5-002
CAS:<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Formula:C17H20N5O7PPurity:99.36%Color and Shape:SolidMolecular weight:437.34RO2468
CAS:<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Formula:C30H30Cl2FN5O4Purity:98%Color and Shape:SolidMolecular weight:614.49Tubulin polymerization-IN-13
CAS:<p>Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.</p>Formula:C20H21NO6Color and Shape:SolidMolecular weight:371.38Sanazole
CAS:<p>Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.</p>Formula:C7H11N5O4Color and Shape:SolidMolecular weight:229.19Flunisolide hemihydrate
CAS:<p>Flunisolide hemihydrate, a corticosteroid with anti-inflammatory properties, treats asthma and rhinitis by inducing eosinophil apoptosis.</p>Formula:C48H64F2O13Color and Shape:SolidMolecular weight:887.024GKK1032B
CAS:<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Formula:C32H39NO4Color and Shape:SolidMolecular weight:501.66RET-IN-8
CAS:<p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Formula:C27H30N6O3Color and Shape:SolidMolecular weight:486.57Anticancer agent 66
CAS:<p>Anticancer agent 66, a ciprofloxacin analog, triggers apoptosis in MCF-7 cells.</p>Formula:C26H23Cl2FN6O2S2Color and Shape:SolidMolecular weight:605.53OXPHOS-IN-1
CAS:<p>OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).</p>Formula:C19H29N3O6S2Color and Shape:SolidMolecular weight:459.58EGFR-IN-52
CAS:<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44SPRC
CAS:<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formula:C6H9NO2SPurity:98%Color and Shape:SolidMolecular weight:159.21Autophagy-IN-2
CAS:<p>Autophagy-IN-2 (7h) blocks autophagic flux, triggers cancer cell death, aids in triple-negative breast cancer study.</p>Formula:C17H19N5OColor and Shape:SolidMolecular weight:309.37Nutlin-1
CAS:<p>Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.</p>Formula:C32H34Cl2N4O4Color and Shape:SolidMolecular weight:609.54NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Formula:C17H17ClN2SPurity:99.28%Color and Shape:SolidMolecular weight:316.85CAY10789
CAS:<p>CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.</p>Formula:C17H15NO2Color and Shape:SolidMolecular weight:265.31Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47Anticancer agent 63
CAS:<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Formula:C17H24F3NOSeColor and Shape:SolidMolecular weight:394.33Cyclamidomycin
CAS:<p>Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.</p>Formula:C7H10N2OColor and Shape:SolidMolecular weight:138.17HIOC
CAS:<p>TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.</p>Formula:C16H19N3O3Color and Shape:SolidMolecular weight:301.34S65487
CAS:<p>S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.</p>Formula:C41H41ClN6O4Purity:99.034%Color and Shape:SolidMolecular weight:717.26NSC405640
CAS:<p>NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]</p>Formula:C12H10Cl2SnColor and Shape:SolidMolecular weight:343.82VS 8
CAS:<p>VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.</p>Formula:C26H20F3N3O3Color and Shape:SolidMolecular weight:479.45VEGFR-2-IN-28
CAS:<p>VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.</p>Formula:C26H17N7O7Color and Shape:SolidMolecular weight:539.46TNF-α-IN-10
CAS:<p>TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].</p>Formula:C17H14O4Color and Shape:SolidMolecular weight:282.29Lexibulin dihydrochloride
CAS:<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Formula:C24H32Cl2N6O2Purity:98%Color and Shape:SolidMolecular weight:507.46Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Formula:C22H19N3O5Color and Shape:SolidMolecular weight:405.4S116836
CAS:<p>S116836 is a tyrosine kinase inhibitor.</p>Formula:C27H21F3N6OPurity:98%Color and Shape:SolidMolecular weight:502.49PD1-PDL1-IN 1
CAS:<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Formula:C14H23N7O6Purity:98%Color and Shape:SolidMolecular weight:385.38MMP-9-IN-5
CAS:<p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>Formula:C27H20IN3O4Color and Shape:SolidMolecular weight:577.37Ro 31-7837
CAS:<p>Ro 31-7837 is an opener of potassium channel.</p>Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Formula:C9H12F2N3O7PColor and Shape:SolidMolecular weight:343.18HDACs/mTOR Inhibitor 1
CAS:<p>HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,</p>Formula:C28H38N8O5Color and Shape:SolidMolecular weight:566.65HDAC1/2 and CDK2-IN-1
CAS:<p>Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.</p>Formula:C26H22ClN7OColor and Shape:SolidMolecular weight:483.95CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Formula:C27H20N8OColor and Shape:SolidMolecular weight:472.5CAY10747
CAS:<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Formula:C42H48FNO6Color and Shape:SolidMolecular weight:681.83PARP1-IN-31
CAS:<p>PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).</p>Formula:C22H15ClFN3O2Purity:98.99%Color and Shape:SolidMolecular weight:407.83SCAL-266
CAS:<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Formula:C27H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:511.54VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36AZD 1152 (hydrochloride)
CAS:<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Formula:C26H33Cl2FN7O6PColor and Shape:SolidMolecular weight:660.47VEGFR-2/BRAF-IN-2
<p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>Formula:C26H21ClF3N5O3S2Color and Shape:SolidMolecular weight:608.05HDAC6-IN-4
CAS:<p>HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.</p>Formula:C30H38N2O5Color and Shape:SolidMolecular weight:506.63p-DDAP
CAS:<p>p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.</p>Formula:C18H31NOPurity:98%Color and Shape:SolidMolecular weight:277.44Nampt-IN-8
CAS:<p>Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.</p>Formula:C36H35N3O4Color and Shape:SolidMolecular weight:573.68NVX-207
CAS:<p>NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.</p>Formula:C36H59NO6Purity:98%Color and Shape:SolidMolecular weight:601.86SK-7041
CAS:<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formula:C19H21N3O3Purity:98%Color and Shape:SolidMolecular weight:339.39ARN5187
CAS:<p>ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.</p>Formula:C24H32FN3OColor and Shape:SolidMolecular weight:397.53Verticillin A
CAS:<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formula:C30H28N6O6S4Purity:98%Color and Shape:SolidMolecular weight:696.84Tubulin/MMP-IN-2
CAS:<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Formula:C40H48NO11PColor and Shape:SolidMolecular weight:749.78TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Formula:C18H9Cl4N5OColor and Shape:SolidMolecular weight:453.11Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Formula:C28H23NO3Color and Shape:SolidMolecular weight:421.49EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Formula:C24H15N5O4S2Color and Shape:SolidMolecular weight:501.54Clidanac
CAS:<p>Clidanac is a potent anti-inflammatory drug and is found to uncouple the oxidative phosphorylation.</p>Formula:C16H19ClO2Purity:98%Color and Shape:SolidMolecular weight:278.77PDE4-IN-10
CAS:<p>PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.</p>Formula:C18H13NColor and Shape:SolidMolecular weight:243.3SKI-I
CAS:<p>SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.</p>Formula:C25H18N4O2Color and Shape:SolidMolecular weight:406.44MBM-17S
CAS:<p>MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and</p>Formula:C36H40N6O10Purity:98%Color and Shape:SolidMolecular weight:716.74MBM-17
CAS:<p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>Formula:C28H28N6O2Purity:98%Color and Shape:SolidMolecular weight:480.56AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Formula:C22H32O2Color and Shape:SolidMolecular weight:328.49Luxeptinib
CAS:<p>Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.</p>Formula:C25H17F4N5O2Color and Shape:SolidMolecular weight:495.43MRS 2693 trisodium salt
CAS:<p>MRS 2693 trisodium salt is a P2Y6 agonist.</p>Formula:C9H22IN5O12P2Purity:98%Color and Shape:SolidMolecular weight:581.15Quinate
CAS:<p>Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.</p>Formula:C26H36N2O9Color and Shape:SolidMolecular weight:520.579AMC-01
CAS:<p>AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.</p>Formula:C27H27BrN2O6Purity:99.95%Color and Shape:SolidMolecular weight:555.42673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27Anticancer agent 99
CAS:<p>Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.</p>Formula:C19H20F3N3O2Color and Shape:SolidMolecular weight:379.38Thioxodihydroquinazolinone-19
CAS:<p>Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.</p>Formula:C16H14N2OSPurity:98%Color and Shape:SolidMolecular weight:282.36hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43IW-927
CAS:<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Formula:C22H23N3O3S2Color and Shape:SolidMolecular weight:441.57EGFR-IN-88
CAS:<p>EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis</p>Formula:C22H18Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:473.37hGGPPS-IN-1
CAS:<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Formula:C13H13N3O6P2SColor and Shape:SolidMolecular weight:401.27Anticancer agent 59
<p>Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.</p>Formula:C42H59NO6Color and Shape:SolidMolecular weight:673.92EGFR-IN-59
CAS:<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Formula:C27H23N5O4SColor and Shape:SolidMolecular weight:513.57PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Formula:C23H22N6O3Color and Shape:SolidMolecular weight:430.46Anticancer agent 58
<p>Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.</p>Formula:C39H55NO5Color and Shape:SolidMolecular weight:617.86MPT0B392
CAS:<p>MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.</p>Formula:C19H20N2O6SColor and Shape:SolidMolecular weight:404.44Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Formula:C20H18O5Color and Shape:SolidMolecular weight:338.35PI3Kδ/γ-IN-3
CAS:<p>PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).</p>Formula:C23H20ClN9OColor and Shape:SolidMolecular weight:473.92SZM-1209
CAS:<p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>Formula:C31H29F5N4O5S2Purity:98%Color and Shape:SolidMolecular weight:696.71CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Formula:C16H12N2O4S3Purity:98%Color and Shape:SolidMolecular weight:392.472,5-Dihydroxybiphenyl
CAS:<p>2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.</p>Formula:C12H10O2Purity:99.66%Color and Shape:White To Grey-Brownish PowderMolecular weight:186.21DRAK1/2-IN-1
CAS:<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Formula:C22H24N2O3SColor and Shape:SolidMolecular weight:396.5ISC-4
CAS:<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Formula:C11H13NSeColor and Shape:SolidMolecular weight:238.19Atopaxar Hydrobromide
CAS:<p>Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54UCB-6876
CAS:<p>UCB-6876 inhibits TNF signaling, stabilizes trimer asymmetry, shows concentration response, and is selective for TNFR1.</p>Formula:C17H18N2OColor and Shape:SolidMolecular weight:266.34FW1256
CAS:<p>FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.</p>Formula:C12H10NOPSColor and Shape:SolidMolecular weight:247.257DG
CAS:<p>7DG is a selective inhibitor of protein kinase R (PKR).</p>Formula:C26H30O5Color and Shape:SolidMolecular weight:422.51ENMD-1068 HCl
CAS:<p>ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.</p>Formula:C15H29N3O2Purity:99.91%Color and Shape:SolidMolecular weight:283.41RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Formula:C23H24N4O4SColor and Shape:SolidMolecular weight:452.53SS28
CAS:<p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>Formula:C18H20O3Purity:98%Color and Shape:SolidMolecular weight:284.35Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Formula:C28H26O8Color and Shape:SolidMolecular weight:490.5Caspase-3-IN-1
CAS:<p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>Formula:C26H25N3O6SColor and Shape:SolidMolecular weight:507.56PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Formula:C29H26N6O3Color and Shape:SolidMolecular weight:506.56Aurora A inhibitor 2
CAS:<p>Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).</p>Formula:C24H26N6O3Color and Shape:SolidMolecular weight:446.5Mammea A/BA
CAS:<p>Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.</p>Formula:C25H26O5Color and Shape:SolidMolecular weight:406.47Epinephrine bitartrate
CAS:<p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>Formula:C13H19NO9Purity:98.6% - 99.07%Color and Shape:White SolidMolecular weight:333.3Tubulin polymerization-IN-17
CAS:<p>Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.</p>Formula:C26H23NO5Color and Shape:SolidMolecular weight:429.46Ludartin
CAS:<p>Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.</p>Formula:C15H18O3Color and Shape:SolidMolecular weight:246.3Arylquin 1
CAS:<p>Arylquin 1: a Par-4 secretagogue targeting vimentin; causes non-apoptotic cancer cell death via LMP.</p>Formula:C17H16FN3Color and Shape:SolidMolecular weight:281.33PD-1/PD-L1-IN-28
CAS:<p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>Formula:C24H24N4O2Color and Shape:SolidMolecular weight:400.47ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Formula:C24H32N4O3Color and Shape:SolidMolecular weight:424.54PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Formula:C20H22N6O4Purity:98%Color and Shape:SolidMolecular weight:410.43CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Formula:C14H15NO4Purity:98%Color and Shape:SolidMolecular weight:261.27Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Formula:C31H34Cl2N6O3P2RuColor and Shape:SolidMolecular weight:772.56EGFR-IN-57
CAS:<p>EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.</p>Formula:C22H15N3O2SColor and Shape:SolidMolecular weight:385.44SID 3712249
CAS:<p>SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).</p>Formula:C17H21N7Purity:98%Color and Shape:SolidMolecular weight:323.4Ozarelix
CAS:<p>Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.</p>Formula:C72H96ClN17O14Color and Shape:SolidMolecular weight:1459.09ATAD2-IN-1
CAS:<p>ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].</p>Formula:C22H26N6O5Color and Shape:SolidMolecular weight:454.48VEGFR-2-IN-23
CAS:<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Formula:C22H15N5O2Color and Shape:SolidMolecular weight:381.39Quinidine polygalacturonate
CAS:<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Formula:C26H34N2O9Color and Shape:SolidMolecular weight:518.22643TH1834 dihydrochloride
CAS:<p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>Formula:C33H42Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:641.63RIP1 kinase inhibitor 6
CAS:<p>RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1</p>Formula:C19H18F2N2O3Purity:98%Color and Shape:SolidMolecular weight:360.35QM31
CAS:<p>QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).</p>Formula:C39H38Cl4N4O4Purity:98%Color and Shape:SolidMolecular weight:768.56IDH1 Inhibitor 9
CAS:<p>IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.</p>Formula:C26H30N4O3Color and Shape:SolidMolecular weight:446.54TRK-IN-23
CAS:<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Formula:C20H17FN4O2Purity:98%Color and Shape:SolidMolecular weight:364.37MpsBAY2a
CAS:<p>carcinoma cell proliferation.</p>Formula:C29H28N6OPurity:98%Color and Shape:SolidMolecular weight:476.57FKGK 18
CAS:<p>FKGK 18: GVIA iPLA2 inhibitor, 99.9% at 0.091 fraction, selective, IC50 ~50 nM–3 μM, reduces blood glucose and diabetes in NOD mice.</p>Formula:C16H15F3OColor and Shape:SolidMolecular weight:280.28Mutant p53 modulator-1
CAS:<p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>Formula:C27H32F4N8O2Color and Shape:SolidMolecular weight:576.59PhiKan 083 hydrochloride
CAS:<p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>Formula:C16H19ClN2Purity:98%Color and Shape:SolidMolecular weight:274.79CAY10506
CAS:<p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>Formula:C20H26N2O4S3Color and Shape:SolidMolecular weight:454.63pan-HER-IN-1
CAS:<p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>Formula:C19H14BrN5OColor and Shape:SolidMolecular weight:408.25Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formula:C29H38FN3O5Purity:97.07% - 98.07%Color and Shape:SolidMolecular weight:527.63α-NETA
CAS:<p>α-NETA is a ChA inhibitor and an ALDH1A1 and CMKLR1 antagonist with anticancer activity and inhibits cholinesterase and acetylcholinesterase (AChE).</p>Formula:C16H20INOPurity:99.54%Color and Shape:SolidMolecular weight:369.24Caylin-2
CAS:<p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>Formula:C32H30F6N4O4Color and Shape:SolidMolecular weight:648.6Antitumor agent-83
<p>Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.</p>Formula:C29H30N6O2Color and Shape:SolidMolecular weight:494.59PHA-690509
CAS:<p>PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.</p>Formula:C17H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:331.43PD-1/PD-L1-IN-25
CAS:<p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>Formula:C26H24ClN3O5Color and Shape:SolidMolecular weight:493.94PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formula:C20H23N3O5Color and Shape:SolidMolecular weight:385.41Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formula:C27H39N3OPurity:98%Color and Shape:SolidMolecular weight:421.62Dipin
CAS:<p>Dipin is an Antineoplastic.</p>Formula:C12H24N6O2P2Purity:98%Color and Shape:SolidMolecular weight:346.31Anticancer agent 55
CAS:<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Formula:C28H21Br2FN2O2Color and Shape:SolidMolecular weight:596.294PDE5-IN-3
CAS:<p>PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.</p>Formula:C21H14BrN5O2Color and Shape:SolidMolecular weight:448.27HI5
CAS:<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Formula:C42H43N5O8Color and Shape:SolidMolecular weight:745.82MMP2-IN-1
CAS:<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Formula:C15H13NO5SColor and Shape:SolidMolecular weight:319.33SLMP53-2
CAS:<p>SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with</p>Formula:C26H22N2O2Color and Shape:SolidMolecular weight:394.47Topoisomerase I inhibitor 2
CAS:<p>ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.</p>Formula:C18H15NO3Color and Shape:SolidMolecular weight:293.32Prinomastat hydrochloride
CAS:<p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>Formula:C18H22ClN3O5S2Purity:98%Color and Shape:SolidMolecular weight:459.97PI3Kα-IN-6
CAS:<p>PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.</p>Formula:C16H15IN2OSColor and Shape:SolidMolecular weight:410.27
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