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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6170 products of "Apoptosis"

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  • Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2


    Thalidomide-PEG conjugate for E3 ligase in PROTACs; has cereblon ligand and 3-unit PEG linker.
    Formula:C27H35F3N4O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:648.58

    Ref: TM-T17917

    100mg
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    500mg
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  • TNF-α Antagonist

    CAS:
    TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with
    Formula:C58H71N11O15S2
    Color and Shape:Solid
    Molecular weight:1226.39

    Ref: TM-T36127

    1mg
    792.00€
    5mg
    3,307.00€
    500µg
    408.00€
  • Ac-LEVD-CHO

    CAS:
    Ac-LEVD-CHO, a caspase-4 inhibitor, is a peptide with the sequence Ac-Leu-Glu-Val-Asp-al [1].
    Formula:C22H36N4O9
    Color and Shape:Solid
    Molecular weight:500.54

    Ref: TM-T85585

    25mg
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    50mg
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    100mg
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  • IDH1/2-IN-1


    IDH1/2-IN-1 (Compound 6b) is a dual inhibitor of IDH1(R132H)/IDH2(R140Q) with IC50 values of 0.22 μM and 1.6 μM, respectively. This compound effectively inhibits tumor growth by suppressing tumor cell proliferation and activating antioxidative enzymes to enhance host defense. Additionally, IDH1/2-IN-1 reduces inflammation and promotes apoptosis, demonstrating significant anti-tumor activity. It is also utilized in leukemia research.
    Color and Shape:Odour Solid

    Ref: TM-T88989

    10mg
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    50mg
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  • Vinepidine sulfate

    CAS:
    Vinepidine (LY-119863) sulfate, a derivative of vincristine, exhibits antitumor activity .
    Formula:C46H58N4O13S
    Color and Shape:Solid
    Molecular weight:907.04

    Ref: TM-T88271

    10mg
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    50mg
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  • Antitumor agent-150


    Antitumor agent-150 (V10) is a breast cancer treatment that functions as a PROTAC degrader of MDM2.
    Formula:C70H106N8O14S
    Molecular weight:1314.75492

    Ref: TM-T209608

    10mg
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    50mg
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  • PD-1/PD-L1-IN-39


    PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with an IC50 value of 15.73 nM. It exhibits strong binding affinity to human and mouse PD-L1, with KD values of 14.62 and 392 nM, respectively. PD-1/PD-L1-IN-39 also demonstrates antitumor activity.
    Formula:C23H20ClFN2O3
    Molecular weight:426.11465

    Ref: TM-T209199

    10mg
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    50mg
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  • PROTAC EGFR degrader 9

    CAS:

    PROTACEGFRdegrader 9 (Compound C6) is an orally active, CRBN-based PROTAC EGFR degrader. It has a DC50 of 10.2 nM and a Kd of 240.2 nM against EGFRL858R/T790M/C797S. PROTACEGFRdegrader 9 demonstrates effective degradation activity against various EGFR mutants while not affecting EGFRWT.

    Formula:C45H48F3N9O6S
    Molecular weight:899.98

    Ref: TM-T209870

    10mg
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    50mg
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  • NAE-IN-1


    NAE-IN-1 (compound X-10) is a potent inhibitor of NAE1. It induces apoptosis and causes cell cycle arrest in the G2/M phase. Furthermore, NAE-IN-1 increases ROS levels and inhibits cell migration, demonstrating antiproliferative activity.
    Formula:C29H30N4O2S
    Molecular weight:498.20895

    Ref: TM-T209353

    10mg
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    50mg
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  • Ru-Poma


    Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.
    Formula:C89H75Cl2N11O11Ru·7H2O

    Ref: TM-T209925

    10mg
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    50mg
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  • OPBP-1


    OPBP-1 is a D-peptide developed through phage display screening, molecular docking, and molecular dynamics simulations. It exhibits high stability, strong antitumor activity, and oral bioavailability. OPBP-1 selectively binds to the PD-L1 protein, significantly blocking the interaction between PD-1 and PD-L1, which helps restore and enhance T lymphocyte function while reducing the proportion of myeloid-derived suppressor cells (MDSCs), counteracting tumor-induced immune evasion. OPBP-1 is applicable for research in cancer immunotherapy.
    Formula:C64H92N20O19S
    Molecular weight:1476.65683

    Ref: TM-TP3626

    10mg
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    50mg
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  • RIP1 kinase inhibitor 9


    RIP1 kinase inhibitor 9 (compound SY-1) is a selective inhibitor of RIP kinase. It effectively reduces central inflammatory responses caused by seizures. RIP1 kinase inhibitor 9 also obstructs Z-VAD-FMK-induced necroptosis in HT-29 cells, with an EC50 of 7.04 nM.
    Formula:C25H21N3O3
    Molecular weight:411.15829

    Ref: TM-T209274

    10mg
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    50mg
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  • PROTAC PD-L1 degrader-1


    PROTACPD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with significant PD-L1 protein degradation capacity. It demonstrates strong PD-L1 degradation activity in 4T1 cells, with a DC50 of 0.609 μM. This compound is applicable to breast cancer research.

    Ref: TM-T210164

    10mg
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    50mg
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  • Anticancer agent 204


    Anticanceragent 204 (Compound 6) is a fluorinated derivative of cinnamamides with anticancer activity. It can arrest the cell cycle of HepG2 cells in the G1 phase and induces apoptosis by reducing mitochondrial membrane polarization (MMP) levels.
    Formula:C26H18FN5O3S
    Molecular weight:499.11144

    Ref: TM-T209605

    10mg
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    50mg
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  • Necrosis inhibitor 2 (hydrocholide)


    Necrosis inhibitor 2 hydrochloride (Compound B19) is an agent that inhibits cellular necrosis. It is useful for researching diseases associated with necrotic pathways, including inflammation, cancer, metabolic disorders, and neurodegenerative diseases.
    Formula:C24H26ClN5O5
    Molecular weight:499.16225

    Ref: TM-T208775

    10mg
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    50mg
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  • Anticancer agent 178


    Anticanceragent 178 (compound C2) is a potent anticancer compound. It effectively inhibits the proliferation and metabolic activity of MDA-MB 231 cells, with IC50 values of 1.1 and 4.2 μM, respectively. Additionally, Anticanceragent 178 induces ferroptosis and necroptosis in cells.
    Formula:C32H30ClFeN2O6
    Molecular weight:629.11418

    Ref: TM-T208865

    10mg
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    50mg
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  • RIPK2-IN-4


    RIPK2-IN-4 is a potent and specific inhibitor of RIPK2 with an IC50 value of 5 nM.
    Formula:C16H10N6S2
    Molecular weight:350.04084

    Ref: TM-T208744

    10mg
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    50mg
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  • Cu(I) chelator 1


    Cu(I) chelator 1 (Compound LH2) is a chelating agent specifically targeting the Cu(I) redox state. It inhibits the production of ROS.
    Formula:C16H27NO4S3
    Molecular weight:393.11022

    Ref: TM-T209189

    10mg
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    50mg
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  • P-gp inhibitor 16


    P-gp inhibitor 16 (compound 14) is an inhibitor of p-glycoprotein. It significantly enhances apoptosis induced by doxorubicin and displays anticancer properties.
    Formula:C35H35N5O4
    Molecular weight:589.2689

    Ref: TM-T208251

    10mg
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    50mg
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  • Camrelizumab

    CAS:

    Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up

    Purity:95% - 98.6%
    Color and Shape:Liquid
    Molecular weight:143.7 kDa

    Ref: TM-T37535

    1mg
    160.00€
    5mg
    547.00€
    10mg
    782.00€
    25mg
    1,159.00€
  • Lw13


    Lw13 is a PROTAC targeting Hsp90, exhibiting maximal degradation efficacy at a concentration of 0.05 μM in Siha cells. Lw13 induces apoptosis and demonstrates potent antitumor activity both in vitro and in vivo.
    Formula:C46H55F3N8O8
    Molecular weight:904.4095

    Ref: TM-T210047

    10mg
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    50mg
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  • SB 699551

    CAS:
    SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.
    Formula:C34H45N3O
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:511.74

    Ref: TM-T23325L

    1mg
    190.00€
    5mg
    471.00€
    10mg
    662.00€
    25mg
    1,036.00€
    50mg
    1,429.00€
    100mg
    1,821.00€
    200mg
    2,489.00€
  • 4-Nitro-3-cresol

    CAS:
    4-Nitro-3-cresol exhibits ciliate toxicity against Tetrahymena pyriformis and is widely used in biochemical experiments and drug synthesis research.
    Formula:C7H7NO3
    Purity:99.87%
    Color and Shape:Beige Powder
    Molecular weight:153.14

    Ref: TM-T21283

    1g
    36.00€
  • Pro-GA

    CAS:
    Pro-GA is a cell-permeable γ-glutamylcyclotransferase (γ-GGCT) inhibitor that inhibit proliferation in multiple bladder cancer cell lines. antitumour.
    Formula:C12H19NO7
    Color and Shape:Solid
    Molecular weight:289.28

    Ref: TM-T203386

    10mg
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    50mg
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  • Claturafenib

    CAS:
    Claturafenib is a brain-permeable, selective, all-mutant BRAF inhibitor.PF-07799933 has shown antitumor activity, used in combination with MEK inhibitors.
    Formula:C18H15Cl2F2N5O3S
    Purity:98.68% - 99.85%
    Color and Shape:Solid
    Molecular weight:490.31

    Ref: TM-T201081

    1mg
    66.00€
    5mg
    145.00€
    10mg
    224.00€
    25mg
    354.00€
    50mg
    To inquire
    1mL*10mM (DMSO)
    172.00€
  • FOXJ1 agonist 1


    FOXJ1 agonist 1 (compound 16c), an orally effective small molecule, effectively enhances FOXJ1 expression and acts on multiciliated cells (MCC) in the mammalian airway system to prevent chronic obstructive pulmonary disease (COPD). Foxj1-IN-1 induces motile cilia production in the respiratory system of both zebrafish and mammals and inhibits elastase-induced COPD in mouse models. Additionally, Foxj1-IN-1 demonstrates good liver microsomal stability and favorable in vivo pharmacokinetic (PK) curves and area under the curve (AUC). It exhibits negligible inhibition of CYP and hERG and lacks significant cytotoxicity.
    Formula:C24H27N5O3
    Color and Shape:Solid
    Molecular weight:433.5

    Ref: TM-T200312

    10mg
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    50mg
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  • Antitumor photosensitizer-7


    Antitumor photosensitizer-7 (compound 15), a photosensitizer possessing anti-cancer properties, demonstrates substantial cytotoxic effects on the G361 melanoma cell line when exposed to 414 nm blue light irradiation.
    Formula:C23H20N2O3
    Color and Shape:Solid
    Molecular weight:372.42

    Ref: TM-T200006

    10mg
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    50mg
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  • Linsidomine hydrochloride

    CAS:
    SIN-1 chloride is a moxidomine metabolite with vasodilatory, anti-platelet, and antianginal effects, reducing myocardial ischemia-related damage.
    Formula:C6H11ClN4O2
    Purity:99.27% - 99.67%
    Color and Shape:White Solid Crystalline
    Molecular weight:206.63

    Ref: TM-T23356

    2mg
    34.00€
    5mg
    50.00€
    10mg
    84.00€
    25mg
    145.00€
    50mg
    To inquire
    1mL*10mM (DMSO)
    56.00€
  • Isomahanine


    Isomahanine is a useful organic compound for research related to life sciences and the catalog number is T125848.
    Formula:C23H25NO2
    Color and Shape:Solid
    Molecular weight:347.458

    Ref: TM-T125848

    1mg
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    5mg
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  • Phosphocreatine dipotassium

    CAS:
    Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives.
    Formula:C4H8K2N3O5P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:287.29

    Ref: TM-T19515

    25mg
    1,369.00€
  • Verproside

    CAS:
    Verproside is a useful organic compound for research related to life sciences. The catalog number is T124745 and the CAS number is 50932-20-2.
    Formula:C22H26O13
    Color and Shape:Solid
    Molecular weight:498.437

    Ref: TM-T124745

    1mg
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    5mg
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  • HTR2A antagonist 1


    HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.
    Formula:C35H43Cl2F2N5O4
    Color and Shape:Solid
    Molecular weight:706.65

    Ref: TM-T204966

    10mg
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    50mg
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  • Verdinexor

    CAS:
    Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
    Formula:C18H12F6N6O
    Purity:98% - 99.68%
    Color and Shape:Solid
    Molecular weight:442.32

    Ref: TM-T6123

    1mg
    35.00€
    5mg
    111.00€
    10mg
    187.00€
    25mg
    341.00€
    50mg
    567.00€
    100mg
    905.00€
    200mg
    1,216.00€
    1mL*10mM (DMSO)
    123.00€
  • WKYMVM

    CAS:
    WKYMVM is a N-formyl peptide receptor (FPR1) agonist.
    Formula:C41H61N9O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:856.11

    Ref: TM-T7484

    1mg
    645.00€
  • Spexin TFA


    Spexin TFA: GAL2/GAL3 agonist (EC50: 45.7/112.2 nM), no activity at GAL1, reduces appetite, fatty acid uptake, and LH secretion; anxiolytic.
    Formula:C76H115F3N20O21S
    Color and Shape:Solid
    Molecular weight:1733.9

    Ref: TM-T76002

    5mg
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    50mg
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  • Z-Ala-Ala-Asp-CMK

    CAS:
    Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor that blocks granzyme B protease activity, for inflammatory diseases and tumours.
    Formula:C19H24ClN3O7
    Purity:99.967%
    Color and Shape:Solid
    Molecular weight:441.86

    Ref: TM-T80745

    1mg
    120.00€
    5mg
    283.00€
    10mg
    472.00€
    25mg
    753.00€
  • RMC-9805

    CAS:
    RMC-9805(Zoldonrasib) is a KRAS G12D inhibitor with anti-tumor and anti-proliferative activity for the study of pancreatic cancer.
    Formula:C63H88F3N11O7
    Purity:98.10% - 99.92%
    Color and Shape:Solid
    Molecular weight:1168.44

    Ref: TM-T78212

    1mg
    127.00€
    5mg
    311.00€
    10mg
    485.00€
    25mg
    795.00€
    50mg
    1,159.00€
    100mg
    1,710.00€
    1mL*10mM (DMSO)
    687.00€
  • ChoKα inhibitor-4


    ChoKα Inhibitor-4 is a bioisosteric agent that effectively inhibits human choline kinase α1 (HChoK α1) with an IC50 of 0.66 μM.
    Color and Shape:Odour Solid

    Ref: TM-T82734

    5mg
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    50mg
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  • S-Adenosyl-L-methionine iodide

    CAS:
    S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].
    Formula:C15H23IN6O5S
    Color and Shape:Solid
    Molecular weight:526.35

    Ref: TM-T74497

    5mg
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    50mg
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  • Syringolin A

    CAS:

    Syringolin A is a useful organic compound for research related to life sciences. The catalog number is T125354 and the CAS number is 212115-96-3.

    Formula:C24H39N5O6
    Color and Shape:Solid
    Molecular weight:493.605

    Ref: TM-T125354

    1mg
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    5mg
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  • AVJ16

    CAS:
    AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.
    Formula:C28H27N3O4
    Purity:98.87% - 99.72%
    Color and Shape:Solid
    Molecular weight:469.53

    Ref: TM-T9980

    1mg
    130.00€
    5mg
    313.00€
    10mg
    500.00€
    25mg
    807.00€
    50mg
    1,108.00€
    100mg
    1,485.00€
    200mg
    1,998.00€
    1mL*10mM (DMSO)
    323.00€
  • DC-Y13-27


    Dc-y13-27, a derivative of DC-Y13, is a potent YTHDF2 inhibitor (KD: 37.9 μM).

    Formula:C14H10N2O2S
    Purity:99.75%
    Color and Shape:Soild
    Molecular weight:270.31

    Ref: TM-T77764

    2mg
    35.00€
    5mg
    52.00€
    10mg
    88.00€
    25mg
    160.00€
    50mg
    235.00€
    100mg
    354.00€
    1mL*10mM (DMSO)
    58.00€
  • Chloranil

    CAS:
    Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.
    Formula:C6Cl4O2
    Purity:98.03%
    Color and Shape:Solid
    Molecular weight:245.88

    Ref: TM-T80673

    1g
    33.00€
  • Z-DQMD-FMK

    CAS:

    Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.

    Formula:C29H40FN5O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:685.72

    Ref: TM-TP2037

    1mg
    309.00€
  • ALK/ROS1 inhibitor 2e HCL


    (R)-1-(2-((2-MeO-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(CF3O)benzyl)piperidine-3-carboxamide HCl is anti-apoptotic and anti-cancer.
    Formula:C30H36ClF3N6O3
    Purity:98.66%
    Color and Shape:Soild
    Molecular weight:621.09

    Ref: TM-T67699L

    1mg
    89.00€
    5mg
    173.00€
    10mg
    259.00€
    25mg
    393.00€
    50mg
    562.00€
    100mg
    778.00€
    200mg
    1,035.00€
  • Human membrane-bound PD-L1 polypeptide

    CAS:
    Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].
    Formula:C85H140N26O36S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2134.24

    Ref: TM-T80209

    1mg
    To inquire
    5mg
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  • H-20

    CAS:
    H-20 is a PD-1 agonist that reduces the required dosage of morphine for analgesia. It can be used in studies related to chronic pain.
    Formula:C44H64N10O15
    Color and Shape:Solid
    Molecular weight:973.037

    Ref: TM-TP3114

    10mg
    To inquire
    50mg
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  • TNF-α (46-65), human

    CAS:
    Human TNF alpha (46-65) peptide.
    Formula:C110H172N24O30
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2310.69

    Ref: TM-TP1626

    100mg
    To inquire
    500mg
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  • AZD5153

    CAS:
    AZD5153 is an orally active and selective BET/BRD4 bromodomain inhibitor with an IC50 value of 1.7nM for BRD4.
    Formula:C25H33N7O3
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:479.57

    Ref: TM-T3504L

    1mg
    43.00€
    5mg
    120.00€
    10mg
    200.00€
    25mg
    356.00€
    50mg
    522.00€
    100mg
    745.00€
    200mg
    982.00€
  • NSD-IN-4


    NSD-IN-4 (Compound A8) is a potent and orally active inhibitor of NSD3, inducing apoptosis in a dose-dependent manner. It demonstrates significant antitumor activity against lung squamous cell carcinoma.
    Formula:C17H12ClFN2O2
    Color and Shape:Solid
    Molecular weight:330.741

    Ref: TM-T205139

    10mg
    To inquire
    50mg
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