Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Pantoprazole sodium
CAS:<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35LW6
CAS:<p>LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.</p>Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68ISRIB (trans-isomer)
CAS:<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Formula:C22H24Cl2N2O4Purity:97.86% - 99.27%Color and Shape:SolidMolecular weight:451.34CHS-828
CAS:<p>CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).</p>Formula:C19H22ClN5OPurity:98% - 99.9%Color and Shape:SolidMolecular weight:371.86MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Formula:C16H13F3N6OPurity:99.76%Color and Shape:SolidMolecular weight:362.31MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46GSK 3 Inhibitor IX
CAS:<p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>Formula:C16H10BrN3O2Purity:98% - 99.72%Color and Shape:SolidMolecular weight:356.17VER-50589
CAS:<p>VER-50589 is a potent HSP90 inhibitor.</p>Formula:C19H17ClN2O5Purity:99.96% - >99.99%Color and Shape:SolidMolecular weight:388.8GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39Larotrectinib sulfate
CAS:<p>Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).</p>Formula:C21H22F2N6O2·H2O4SPurity:98.62% - 99.76%Color and Shape:SolidMolecular weight:526.51Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
CAS:<p>Thalidomide-O-amido-PEG-C2-NH2 HCl is a cereblon ligand-linker for PROTAC synthesis.</p>Formula:C19H23ClN4O7Purity:95%Color and Shape:SolidMolecular weight:454.862GSK-J4
CAS:<p>GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.</p>Formula:C24H27N5O2Purity:98.24% - 99.98%Color and Shape:SolidMolecular weight:417.5Mirdametinib
CAS:<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Formula:C16H14F3IN2O4Purity:99.11% - 99.63%Color and Shape:White PowderMolecular weight:482.19Soyasapogenol B
CAS:<p>Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.</p>Formula:C30H50O3Purity:99.51% - 99.81%Color and Shape:SolidMolecular weight:458.72Cynaroside
CAS:<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Formula:C21H20O11Purity:98% - >99.99%Color and Shape:SolidMolecular weight:448.38Darapladib
CAS:<p>Darapladib (SB-480848) is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with an IC50 value of 0.25 nM.Cost-effective and quality-assured.</p>Formula:C36H38F4N4O2SPurity:99.82% - >99.99%Color and Shape:SolidMolecular weight:666.77Capmatinib xHCl
CAS:<p>Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50</p>Formula:C23H18ClFN6OPurity:98.62% - 99.81%Color and Shape:SolidMolecular weight:448.89A-1155463
CAS:<p>A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2, BCL-W and MCL-1.</p>Formula:C35H32FN5O4S2Purity:96.1% - 99%Color and Shape:SolidMolecular weight:669.79Angelicin
CAS:<p>Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.</p>Formula:C11H6O3Purity:99.86% - 99.89%Color and Shape:White SolidMolecular weight:186.16L-Ascorbic acid sodium salt
CAS:<p>L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.</p>Formula:C6H7NaO6Purity:98.73% - 99.75%Color and Shape:Less Solid PowderMolecular weight:198.11PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Formula:C24H21N5O2Purity:99.33%Color and Shape:SolidMolecular weight:411.46Fimasartan
CAS:<p>Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.</p>Formula:C27H31N7OSPurity:98.96%Color and Shape:SolidMolecular weight:501.65Lenalidomide hemihydrate
CAS:<p>Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.</p>Formula:C13H13N3O3H2OPurity:96.22%Color and Shape:SolidMolecular weight:268.28Desoxyrhaponticin
CAS:<p>Deoxyrhaponticin may reduce post-meal blood sugar and inhibit cancer cell growth.</p>Formula:C21H24O8Purity:99.97% - ≥95%Color and Shape:SolidMolecular weight:404.41BTR-1
CAS:<p>5-Benzylidene-3-ethyl rhodanine(BTR-1 (5-Benzylidene-3-ethyl rhodanine)) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.</p>Formula:C12H11NOS2Purity:98%Color and Shape:SolidMolecular weight:249.35Crebanine
CAS:<p>Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.</p>Formula:C20H21NO4Purity:99.17% - 99.77%Color and Shape:SolidMolecular weight:339.39GDC-0623
CAS:<p>GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.</p>Formula:C16H14FIN4O3Purity:98.95% - 99.02%Color and Shape:SolidMolecular weight:456.21Devimistat
CAS:<p>Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase</p>Formula:C22H28O2S2Purity:98.06% - 99.24%Color and Shape:SolidMolecular weight:388.59ASTX660
CAS:<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:SolidMolecular weight:539.68CA-5f
CAS:<p>CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.</p>Formula:C24H24N2O3Purity:99.69%Color and Shape:SolidMolecular weight:388.46Alda-1
CAS:<p>Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.</p>Formula:C15H11Cl2NO3Purity:98.5% - 99.63%Color and Shape:SolidMolecular weight:324.16Z-FA-FMK
CAS:<p>Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.</p>Formula:C21H23FN2O4Purity:98.84% - 99.68%Color and Shape:SolidMolecular weight:386.42PFK-158
CAS:<p>PFK-158 is an effective and specific inhibitor PFKFB3.</p>Formula:C18H11F3N2OPurity:95.49% - 99.16%Color and Shape:SolidMolecular weight:328.29Madecassoside
CAS:<p>Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activities</p>Formula:C48H78O20Purity:99.46% - 99.85%Color and Shape:White PowderMolecular weight:975.12Necroptosis-IN-1
CAS:<p>Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.</p>Formula:C12H10ClN3O2Purity:99.73% - 99.8%Color and Shape:SolidMolecular weight:263.68Mivebresib
CAS:<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47Palomid 529
CAS:<p>Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.</p>Formula:C24H22O6Purity:98.40% - 98.59%Color and Shape:SolidMolecular weight:406.43Karanjin
CAS:<p>Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.</p>Formula:C18H12O4Purity:99.01%Color and Shape:SolidMolecular weight:292.29HYPOCRELLIN B
CAS:<p>HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.</p>Formula:C30H24O9Purity:98% - 98.87%Color and Shape:SolidMolecular weight:528.51Malachite green oxalate
CAS:<p>Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.</p>Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51Anagrelide
CAS:<p>Anagrelide (Xagrid) is a Platelet-reducing Agent.</p>Formula:C10H7Cl2N3OPurity:99.53% - >99.99%Color and Shape:SolidMolecular weight:256.09Tetrahydroxyquinone monohydrate
CAS:<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Formula:C6H6O7Color and Shape:SolidMolecular weight:190.11Diallyl Trisulfide
CAS:<p>Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.</p>Formula:C6H10S3Purity:95% - ≥98%Color and Shape:LiquidMolecular weight:178.34Cabozantinib hydrochloride
CAS:<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Adaphostin
CAS:<p>Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.</p>Formula:C24H27NO4Purity:98.29%Color and Shape:SolidMolecular weight:393.48Liensinine
CAS:<p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>Formula:C37H42N2O6Purity:98.92% - 99.93%Color and Shape:White-Like PowderMolecular weight:610.74BI-6C9
CAS:<p>BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.</p>Formula:C23H25N3O4S2Purity:98.39%Color and Shape:SolidMolecular weight:471.59Nimustine Hydrochloride
CAS:<p>Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.</p>Formula:C9H14Cl2N6O2Purity:98.80%Color and Shape:SolidMolecular weight:309.15
