Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(27 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6059 products of "Apoptosis"
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Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurity:98.89% - >99.99%Color and Shape:SolidMolecular weight:454.63Dacarbazine citrate
CAS:Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.Formula:C12H18N6O8Color and Shape:SolidMolecular weight:374.31FOXO4-DRI acetate
FOXO4-DRI acetate is a bioactive chemical.Formula:C36H64N14O14SPurity:99.10%Color and Shape:SolidMolecular weight:5358.06Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purity:99.66% - 99.74%Color and Shape:SolidMolecular weight:696.82TrxR1-IN-B19
CAS:TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stressFormula:C21H22O5Purity:98.6%Color and Shape:SolidMolecular weight:354.4Thalidomide-O-amido-C3-NH2 TFA
CAS:Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.Formula:C20H21F3N4O8Purity:98.47%Color and Shape:SolidMolecular weight:502.4Thalidomide-O-COOH
CAS:Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.Formula:C15H12N2O7Purity:98% - 98.29%Color and Shape:SolidMolecular weight:332.27Methoxychlor
CAS:<p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>Formula:C16H15Cl3O2Purity:98.82% - ≥95%Color and Shape:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfMolecular weight:345.65Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Color and Shape:SolidMolecular weight:377.31GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Formula:C30H34ClN5O3Purity:97.26% - 98.35%Color and Shape:SolidMolecular weight:548.08Thalidomide-4-OH
CAS:<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Formula:C13H10N2O5Purity:99.59%Color and Shape:SolidMolecular weight:274.23Thalidomide-NH-C4-NH-Boc
CAS:Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.Formula:C22H28N4O6Purity:98.87%Color and Shape:SolidMolecular weight:444.48Difurazon hydrochloride
CAS:Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.Formula:C14H13ClN6O6Purity:98.51%Color and Shape:SolidMolecular weight:396.74Methoxyamine HCl
CAS:Methoxyamine HCl targets DNA repair sites, potentially increasing DNA breaks and enhancing alkylating agents' anti-cancer effects.Formula:CH6ClNOPurity:≥98%Color and Shape:SolidMolecular weight:83.51Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purity:99.94% - >99.99%Color and Shape:White PowderMolecular weight:461.51OICR-9429
CAS:<p>OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.</p>Formula:C29H32F3N5O3Purity:97.07% - 99.93%Color and Shape:SolidMolecular weight:555.59Thalidomide-O-amido-PEG3-C2-NH2 TFA
CAS:Synthetic E3 ligase ligand-linker, Thalidomide-O-amido-PEG3-C2-NH2 TFA, used in PROTAC with cereblon ligand and PEG.Formula:C25H31F3N4O11Purity:99.82%Color and Shape:SolidMolecular weight:620.54Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formula:C17H20O5Purity:99.61% - 99.72%Color and Shape:SolidMolecular weight:304.34KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Formula:C30H37ClN8O4Purity:96.19%Color and Shape:SolidMolecular weight:609.12Perhexiline
CAS:Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.Formula:C19H35NColor and Shape:SolidMolecular weight:277.49Ketorolac hemicalcium
CAS:Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.Formula:C30H24CaN2O6Color and Shape:SolidMolecular weight:548.608Thalidomide-propargyl
CAS:Thalidomide-propargyl, a Cereblon ligand, links proteins in PROTAC formation.Formula:C16H12N2O5Purity:95.14%Color and Shape:SolidMolecular weight:312.28Thalidomide-NH-C6-NH2 hydrochloride
CAS:<p>Pomalidomide-C6-NH2 HCl is a synthetic conjugate for PROTAC, combining CRBN ligand and linker.</p>Formula:C19H25ClN4O4Purity:99.27%Color and Shape:SolidMolecular weight:408.88Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formula:C19H26O7Purity:98% - 99.98%Color and Shape:SolidMolecular weight:366.41Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purity:95.37% - 99.82%Color and Shape:Dark Green To Black SolidMolecular weight:718.79Sulfaphenazole
CAS:<p>Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for</p>Formula:C15H14N4O2SPurity:97.53% - 99.67%Color and Shape:SolidMolecular weight:314.36PK11000
CAS:PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.Formula:C6H5ClN2O4SPurity:99.70%Color and Shape:SolidMolecular weight:236.63Abacavir monosulfate
CAS:Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.Formula:C14H20N6O5SColor and Shape:SolidMolecular weight:384.41Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.03(ZE)-SU9516
CAS:(ZE)-SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.Formula:C13H11N3O2Purity:99.59%Color and Shape:SolidMolecular weight:241.25Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Formula:C14H10Cl2KNO2Purity:99.51%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:334.24Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS:<p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>Formula:C23H27F3N4O10Purity:95.74% - 99%Color and Shape:SolidMolecular weight:576.48IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:351.4Cystamine dihydrochloride
CAS:Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.Formula:C4H14Cl2N2S2Purity:98.91% - 99.81%Color and Shape:White PowderMolecular weight:225.19MS7972
CAS:MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μMFormula:C14H13NO2Purity:99.78%Color and Shape:SolidMolecular weight:227.26KX2-361
CAS:KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormula:C24H24FN3O2Purity:99.64% - 99.68%Color and Shape:SolidMolecular weight:405.46Fipronil
CAS:Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.Formula:C12H4Cl2F6N4OSPurity:97.21%Color and Shape:Solid PowderMolecular weight:437.15Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74Pomolic acid
CAS:Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-Formula:C30H48O4Purity:96.84% - 99.79%Color and Shape:SolidMolecular weight:472.7Crebanine
CAS:Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.Formula:C20H21NO4Purity:99.17% - 99.77%Color and Shape:SolidMolecular weight:339.39DEL-22379
CAS:DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.Formula:C26H28N4O3Purity:99.3% - 99.53%Color and Shape:SolidMolecular weight:444.53Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Formula:C18H20N3NaO3SPurity:98% - 99.912%Color and Shape:White Or Off White Crystalline PowderMolecular weight:381.42Deltamethrin
CAS:Deltamethrin, a pyrethroid insecticide, causes reversible hind limb rigidity in rats and is used for crop protection and disease control.Formula:C22H19Br2NO3Purity:99.25% - 99.85%Color and Shape:White To Off-White Crystals Or PowderMolecular weight:505.20Mitochonic acid 5
CAS:MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.Formula:C18H13F2NO3Purity:98.85%Color and Shape:SolidMolecular weight:329.3Nutlin-3
CAS:Nutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction and activates p53. Nutlin-3 has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purity:98.13% - 99.89%Color and Shape:SolidMolecular weight:581.49Desmorpholinyl Navitoclax-NH-Me
CAS:<p>Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a</p>Formula:C44H51ClF3N5O5S3Purity:99.87%Color and Shape:SolidMolecular weight:918.55Avadomide HCl
CAS:Avadomide (CC-122), an oral drug, targets CRBN, degrades Ikaros/Aiolos, and mimics interferon, showing antitumor effects in DLBCL.Formula:C14H15ClN4O3Color and Shape:SolidMolecular weight:322.75NAE-IN-M22
CAS:NAE-IN-M22: Selective, potent NEDD8 enzyme inhibitor; blocks cancer cell growth; induces apoptosis in A549 cells; effective in vivo.Formula:C20H24Cl2N2Purity:97.65%Color and Shape:SolidMolecular weight:363.32Anagrelide hydrochloride
CAS:<p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>Formula:C10H7Cl2N3O·HClPurity:99.58%Color and Shape:Off-White PowderMolecular weight:292.55
