Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(27 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6063 products of "Apoptosis"
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UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Nodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Formula:C14H13N3O2SPurity:99.97% - >99.99%Color and Shape:SolidMolecular weight:287.34Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Formula:C15H12O6Color and Shape:SolidMolecular weight:288.25Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1030.29Calcimycin
CAS:<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Formula:C29H37N3O6Purity:98%Color and Shape:SolidMolecular weight:523.62Amantadine
CAS:<p>Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.</p>Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4Nitidine chloride
CAS:1.Formula:C21H18ClNO4Purity:96.59% - 99.55%Color and Shape:SolidMolecular weight:383.82GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formula:C25H23ClN2O3Purity:98.34% - 99.85%Color and Shape:SolidMolecular weight:434.91MPI-0479605
CAS:MPI-0479605 is an ATP competitive and selective inhibitor.Formula:C22H29N7OPurity:97.59% - >99.99%Color and Shape:SolidMolecular weight:407.51(-)-Alkannin
CAS:<p>(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects.</p>Formula:C16H16O5Purity:98.18% - 98.8%Color and Shape:White Or Slightly Yellow Crystalline Powder SolidMolecular weight:288.3TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurity:99.89%Color and Shape:SolidMolecular weight:273.23Dihydrorotenone
CAS:Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.Formula:C23H24O6Purity:98.98% - 99.58%Color and Shape:SolidMolecular weight:396.43Methyl protodioscin
CAS:Methyl protodioscin boosts HDL, lowers LDL and triglycerides, has anti-cancer effects, and promotes apoptosis via mitochondrial pathways.Formula:C52H86O22Purity:99.308% - 99.73%Color and Shape:SolidMolecular weight:1063.23Scriptaid
CAS:Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Formula:C18H18N2O4Purity:96.74% - 99.45%Color and Shape:SolidMolecular weight:326.35Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formula:C22H30N6OSBrHPurity:97.83% - 99.92%Color and Shape:SolidMolecular weight:628.86Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Formula:C10H13Cl2NPurity:99.54%Color and Shape:SolidMolecular weight:218.12Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purity:97.58% - 98%Color and Shape:SolidMolecular weight:330.359-Methoxycamptothecin
CAS:9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.Formula:C21H18N2O5Purity:98.49% - 99.56%Color and Shape:SolidMolecular weight:378.38Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Formula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.5NSC 73150
CAS:6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.Formula:C12H12N4O2Purity:99.84%Color and Shape:SolidMolecular weight:244.25TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.44BMS-833923
CAS:BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).Formula:C30H27N5OPurity:99.47% - 99.76%Color and Shape:SolidMolecular weight:473.574E1rcat
CAS:<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Formula:C28H18N2O6Purity:99.47%Color and Shape:SolidMolecular weight:478.45EI1
CAS:EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.Formula:C23H26N4O2Purity:99.93%Color and Shape:SolidMolecular weight:390.484-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurity:97.18%Color and Shape:SolidMolecular weight:313.42pimpinellin
CAS:<p>Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.</p>Formula:C13H10O5Purity:99.85% - ≥95%Color and Shape:SolidMolecular weight:246.22β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Formula:C15H14O3Purity:99.76% - 99.88%Color and Shape:SolidMolecular weight:242.27MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formula:C27H26N2O4SPurity:97.27% - 99.57%Color and Shape:SolidMolecular weight:474.57DAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formula:C23H26F2N2O4Purity:98.06% - 99.81%Color and Shape:White SolidMolecular weight:432.46Isatin
CAS:Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.Formula:C8H5NO2Purity:98.92%Color and Shape:Yellow To Reddish Crystalline SolidMolecular weight:147.13BDA-366
CAS:BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies itsFormula:C24H29N3O4Purity:98.61%Color and Shape:SoildMolecular weight:423.53BDO
CAS:3BDO is a new mTOR activator. 3BDO inhibits autophagy.Formula:C18H17NO5Purity:97.76%Color and Shape:SolidMolecular weight:327.33UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Formula:C32H43N5O2Purity:98% - 99.04%Color and Shape:SolidMolecular weight:529.72H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purity:>99.99%Color and Shape:SolidMolecular weight:614.61Sodium dichloroacetate
CAS:Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Formula:C2HCl2NaO2Purity:99.32% - 99.87%Color and Shape:White PowderMolecular weight:150.92N-Formyl-Met-Leu-Phe
CAS:N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Formula:C21H31N3O5SPurity:98.69% - 98.69%Color and Shape:SolidMolecular weight:437.55Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Formula:C30H48O5Purity:96.91% - 99.97%Color and Shape:SolidMolecular weight:488.70Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Formula:C20H20O4Purity:98% - 99.76%Color and Shape:SolidMolecular weight:324.37Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Formula:C22H24N2O7SPurity:98.13% - 99.95%Color and Shape:SolidMolecular weight:460.50Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formula:C21H22ClNO4Purity:97.9% - 99.47%Color and Shape:SolidMolecular weight:387.86Polyporenic acid C
CAS:Polyporenic acid C shows inhibitory activity against human collagenase.Formula:C31H46O4Purity:96.84% - 99.90%Color and Shape:SolidMolecular weight:482.69Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24IACS-010759
CAS:IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.Formula:C25H25F3N6O4SPurity:99.54% - 99.73%Color and Shape:SolidMolecular weight:562.56TPCA-1
CAS:TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinasesFormula:C12H10FN3O2SPurity:95.03% - 97.86%Color and Shape:SolidMolecular weight:279.29ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurity:98.42% - 99.55%Color and Shape:SolidMolecular weight:477.4MDK83190
CAS:<p>MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .</p>Formula:C15H9Cl2NO2Purity:97.40% - 98%Color and Shape:Orange SolidMolecular weight:306.14Poziotinib
CAS:Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formula:C23H21Cl2FN4O3Purity:98.69% - 99.78%Color and Shape:SolidMolecular weight:491.34BG45
CAS:BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.Formula:C11H10N4OPurity:99.77%Color and Shape:SolidMolecular weight:214.22INCB-057643
CAS:INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Formula:C20H21N3O5SPurity:99.5%Color and Shape:SolidMolecular weight:415.46
