Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(110 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(65 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6105 products of "Apoptosis"
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Zotatifin
CAS:Zotatifin (eFT226) is a selective eIF4A inhibitor with antiviral and antitumor properties, inhibiting Sox4 translation and inducing apoptosis.Formula:C28H29N3O5Purity:98.85%Color and Shape:SolidMolecular weight:487.55Gemcitabine elaidate hydrochloride
CAS:CP-4126, a lipophilic pro-drug of Gemcitabine, converts to active form by esterases, allowing oral administration with dose-dependent effects.
Formula:C27H44ClF2N3O5Purity:98.50% - 99.6%Color and Shape:SolidMolecular weight:564.11JAK2-IN-7
CAS:JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 arrest, apoptosis, and has antitumor effects.Formula:C26H33N7OPurity:99.54%Color and Shape:SolidMolecular weight:459.59Ref: TM-T35900
1mg145.00€5mg354.00€10mg630.00€25mg1,301.00€50mg1,738.00€100mg2,357.00€1mL*10mM (DMSO)358.00€FX-11
CAS:FX-11: potent LDHA inhibitor (Ki 8 μM), activates PKM2, reduces ATP, induces oxidative stress/ROS, cell death, shows antitumor effects.
Formula:C22H22O4Purity:98.95%Color and Shape:SolidMolecular weight:350.41β-Zearalanol
CAS:Beta-Zearalenol, a derivative of zearalenone (ZEA) capable of conjugating with glucuronic acid[2], is a mycotoxin produced by Fusarium spp. It induces apoptosis and oxidative stress in mammalian reproductive cells[1].Formula:C18H26O5Color and Shape:SolidMolecular weight:322.4OBAA
CAS:OBAA is a potent inhibitor of phospholipase A2 (PLA2) with an IC 50 of 70 nM. OBAA blocks Melittin-induced Ca 2+ influx in Trypanosoma brucei with an IC 50 of 0.4 μM [1] [2] [3].Formula:C28H44O3Purity:98%Color and Shape:SolidMolecular weight:428.65AP1867-3-(aminoethoxy)
CAS:AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.Formula:C38H50N2O9Color and Shape:SolidMolecular weight:678.81PIM-447 dihydrochloride
CAS:PIM-447 dihydrochloride is an orally available and selective inhibitor of pan-PIM kinase(Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively).Formula:C24H25Cl2F3N4OPurity:98%Color and Shape:SolidMolecular weight:513.38WEHI-539 hydrochloride
CAS:WEHI-539 hydrochloride is a selective Bcl-XL inhibitor with an IC50 of 1.1 nM.Formula:C31H30ClN5O3S2Purity:98%Color and Shape:SolidMolecular weight:620.18(R)-Verapamil hydrochloride
CAS:(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an inhibitor of P-Glycoprotein.Formula:C27H39ClN2O4Color and Shape:SolidMolecular weight:491.065-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Formula:C9H14N4O5Purity:95%Color and Shape:SolidMolecular weight:258.2313PRGL493
CAS:PRGL493 blocks ACSL4, halts PC3/MDA-MB-231 cancer cell spread, and inhibits MA-10 tumor progesterone. Effective in mouse PC3 tumor model at 0.25 mg/kg.Formula:C25H21N7O2Purity:98.80% - 99.11%Color and Shape:SolidMolecular weight:451.48Ref: TM-T35666
Discontinued productPlatinum, diammine[1,1-cyclobutanedi(carboxylato-kO)(2-)]-, (SP-4-2)-
CAS:Formula:C6H10N2O4PtPurity:98%Color and Shape:SolidMolecular weight:369.2326Ac-IETD-CHO TFA
Ac-IETD-CHO TFA is a granzyme B and caspase-8 inhibitor that inhibits caspase8 activity by blocking caspase3 precursor cleavage.Ac-IETD-CHO TFA inhibits Fas-mediated apoptosis.Formula:C23H35F3N4O12Color and Shape:SoildMolecular weight:616.54Thalidomide-5-COOH
CAS:Thalidomide-5-COOH is a useful organic compound for research related to life sciences. The catalog number is T64600 and the CAS number is 1216805-11-6.Formula:C14H10N2O6Color and Shape:SolidMolecular weight:302.242A-192621
CAS:A-192621 is a potent, nonpeptide, orally active, and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. A-192621 promotes apoptosis in PASMCs and elevates both arterial blood pressure and plasma ET-1 levels[1][2][3]. Its selectivity is 636-fold higher for ETB than ETA (IC50 of 4280 nM and Ki of 5600 nM).Formula:C33H38N2O6Purity:98%Color and Shape:SolidMolecular weight:558.66DB818
CAS:DB818 is a synthetic Homeobox A9 (HOXA9) inhibitor and can be used for research on the treatment of acute myeloid leukaemia associated with HOXA9 overexpression.Formula:C19H16N6SPurity:98%Color and Shape:SolidMolecular weight:360.44MI-773
CAS:MI-773 is a potent inhibitor of the MDM2-p53 protein interaction (PPI) with a high affinity for MDM2 and a Kd value of 8.2 nM. MI-773 exhibits antitumour effects.Formula:C29H34Cl2FN3O3Color and Shape:SolidMolecular weight:562.5Thalidomide-O-C5-NH2 hydrochloride
CAS:Thalidomide-O-C5-NH2 hydrochloride is a synthetic compound consisting of a ligand-linker conjugate with E3 ligase activity. It combines a cereblon ligand based on Thalidomide and a linker commonly utilized in PROTAC technology.Formula:C18H22ClN3O5Color and Shape:SolidMolecular weight:395.84Yatein
CAS:Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity.Formula:C22H24O7Purity:98%Color and Shape:SolidMolecular weight:400.42
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