Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(116 products)
- CDK(547 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(46 products)
- Dynamin(27 products)
- Ferroptosis(233 products)
- HSP(180 products)
- Integrin(276 products)
- Kinesin(87 products)
- LIM Kinase(21 products)
- Microtubule Associated(273 products)
- PKC(128 products)
- PLK(25 products)
- ROCK(61 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(77 products)
Show 10 more subcategories
Found 3934 products of "Cell Cycle/Checkpoint"
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5'-O-DMT-N4-Bz-5-Me-dC
CAS:5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formula:C38H37N3O7Purity:98.88%Color and Shape:SolidMolecular weight:647.72PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:SolidMolecular weight:453.9Ref: TM-T84770
1mg84.00€5mg170.00€1mL*10mM (DMSO)195.00€10mg281.00€25mg542.00€50mg757.00€100mg1,044.00€USP1-IN-2
CAS:USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Formula:C26H22F4N6OPurity:99.69% - 99.88%Color and Shape:SolidMolecular weight:510.486Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Formula:C14H9ClN2O3SPurity:98.56% - 99.42%Color and Shape:SolidMolecular weight:320.75Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formula:C15H27N7O8Purity:98.29%Color and Shape:SolidMolecular weight:433.422'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formula:C13H19N5O5Purity:99.35%Color and Shape:SolidMolecular weight:325.32LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Formula:C25H28F2N8Purity:99.14%Color and Shape:SolidMolecular weight:478.54DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purity:99.13%Color and Shape:SolidMolecular weight:349.34Ref: TM-T37655
1mg73.00€5mg160.00€1mL*10mM (DMSO)170.00€10mg236.00€25mg409.00€50mg595.00€100mg858.00€Braco-19
CAS:Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.Formula:C35H43N7O2Purity:97.01%Color and Shape:SolidMolecular weight:593.765-Bromo-2',3',5'-tri-O-acetyluridine
CAS:5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formula:C15H17BrN2O9Purity:99%Color and Shape:SolidMolecular weight:449.212'-O-Methyl-2-thiouridine
CAS:2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Formula:C10H14N2O5SPurity:99.89%Color and Shape:SolidMolecular weight:274.295-Hydroxyuridine
CAS:5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.Formula:C9H12N2O7Purity:98.76%Color and Shape:SolidMolecular weight:260.2N6-Methyl-2'-O-methyladenosine
CAS:N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFormula:C12H17N5O4Purity:99.97%Color and Shape:SolidMolecular weight:295.299-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormula:C10H13N5O4Purity:99.97%Color and Shape:SolidMolecular weight:267.24Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurity:98.28%Color and Shape:SolidMolecular weight:415.46Ref: TM-T37113
1mg35.00€5mg75.00€1mL*10mM (DMSO)87.00€10mg105.00€25mg173.00€50mg255.00€100mg371.00€200mg530.00€2'-Deoxy-N4-methylcytidine
CAS:2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Formula:C10H15N3O4Purity:99.61%Color and Shape:SolidMolecular weight:241.24Rabacfosadine
CAS:Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Formula:C21H35N8O6PPurity:99.06% - 99.37%Color and Shape:SolidMolecular weight:526.53CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formula:C18H15F5N8OPurity:99.37%Color and Shape:SolidMolecular weight:454.36Ref: TM-T40290
1mg157.00€5mg378.00€1mL*10mM (DMSO)416.00€10mg612.00€25mg1,251.00€50mg1,972.00€100mg2,673.00€RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formula:C24H19Cl3N2O4Purity:98.26%Color and Shape:SolidMolecular weight:505.782'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Formula:C10H12IN5O3Purity:99.37%Color and Shape:SolidMolecular weight:377.142'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Formula:C11H15N5O4Purity:99.79%Color and Shape:SolidMolecular weight:281.27O6-Methyldeoxy guanosine
CAS:O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Formula:C11H15N5O4Purity:99.57%Color and Shape:SolidMolecular weight:281.27N6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormula:C18H21N5O5Purity:99.79%Color and Shape:SolidMolecular weight:387.39Ref: TM-TNU0430
1mg141.00€2mg203.00€5mg344.00€10mg505.00€25mg797.00€50mg1,044.00€100mg1,431.00€200mg1,953.00€Levomefolate sodium
CAS:Levomefolate sodium (L-5-MTHF sodium) is a dietary supplement that can be used to study megaloblastic anemia and neurological disorders.Formula:C20H23N7Na2O6Purity:98.7%Color and Shape:SolidMolecular weight:503.42PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formula:C23H25F3N6O2Purity:98%Color and Shape:SolidMolecular weight:474.48SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurity:98.29%Color and Shape:SolidMolecular weight:463Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formula:C26H36N6O3Purity:96.24% - 99.75%Color and Shape:SolidMolecular weight:480.6MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurity:99.22%Color and Shape:SolidMolecular weight:461.945-Methyl-5,6-dihydrouridine
CAS:5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.Formula:C10H16N2O6Purity:98%Color and Shape:SolidMolecular weight:260.24Pavurutamab
CAS:Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.Color and Shape:LiquidN6-Etheno 2'-deoxyadenosine
CAS:N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.Formula:C12H13N5O3Purity:98%Color and Shape:SolidMolecular weight:275.26Acapatamab
CAS:Acapatamab (AMG-160) is a Half-Life Extended (HLE) Bispecific T-cell Engager (BiTE) with domains that bind to PSMA and CD3. It exhibits Kd values of 14.8 nM for hPSMA and 22.4 nM for hCD3. This compound is utilized in cancer research.Color and Shape:LiquidOS-2966
OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaIluzanebart
CAS:Iluzanebart, a hTREM2 agonist antibody, enhances microglial survival and function, modeling CSF1R-ALSP and microglial dysfunction in neurodegenerative studies.Purity:95% - 97.7% (SDS-PAGE); 98.3% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.90 kDaAnti-Mouse CD32/CD16 Antibody (2.4G2)
Anti-Mouse CD32/CD16 Antibody is a rat-derived IgG2b inhibitor targeting the mouse CD32/CD16 antigens.Color and Shape:Odour LiquidMolecular weight:150 kDaGresonitamab
CAS:Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.Color and Shape:LiquidVibecotamab
CAS:Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.Color and Shape:LiquidGSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Formula:C31H30F4N4O5SPurity:99.141%Color and Shape:SoildMolecular weight:646.65Caplacizumab
CAS:Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additionalColor and Shape:LiquidAlnuctamab
CAS:Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].Color and Shape:LiquidPOSH-IN-1
CAS:POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.Formula:C14H8FNO3SPurity:99.29%Color and Shape:SolidMolecular weight:289.28Locked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Formula:C32H32N2O8Purity:98%Color and Shape:SolidMolecular weight:572.61Viltolarsen
CAS:Viltolarsen targets exon 53 in the dystrophin gene for Duchenne muscular dystrophy research.Color and Shape:SolidMetribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Formula:C8H14N4OSPurity:99.07%Color and Shape:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Molecular weight:214.29Enlimomab
CAS:Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.Color and Shape:LiquidDHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Formula:C18H16N2O3S2Color and Shape:SolidMolecular weight:372.46Rovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Purity:95% - 95%Color and Shape:LiquidRinatabart
CAS:Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.Purity:95% - 95.7% (SDS-PAGE); 96.0% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.18 kDaAnti-Mouse TCR γ/δ Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.Color and Shape:Odour LiquidObrindatamab
CAS:Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.Color and Shape:LiquidVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Color and Shape:LiquidPacanalotamab
CAS:Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.Color and Shape:LiquidVatelizumab
CAS:Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaLinvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Color and Shape:LiquidPasotuxizumab
CAS:Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.Color and Shape:LiquidVepsitamab
CAS:Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.Color and Shape:LiquidVVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formula:C20H21F2N3O4SPurity:99.24% - 99.93%Color and Shape:SoildMolecular weight:437.46Ref: TM-T85309
1mg69.00€5mg147.00€1mL*10mM (DMSO)164.00€10mg224.00€25mg358.00€50mg512.00€100mg707.00€Vixtimotamab
Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively engages human CD33 and CD3 antigens.Color and Shape:Odour LiquidFlotetuzumab
CAS:Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.Color and Shape:LiquidTepoditamab
CAS:Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.Color and Shape:LiquidUbamatamab
CAS:Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].Purity:95%Color and Shape:LiquidAnti-Mouse CD3ε Antibody (145-2C11)
Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activationPurity:99%Color and Shape:Odour LiquidMolecular weight:150 kDaVoxalatamab
CAS:Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].Color and Shape:LiquidTilatamig samrotecan
Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.Color and Shape:Odour SolidhDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Formula:C19H16N2O2Purity:98%Color and Shape:SolidMolecular weight:304.349L-Threonolactone
CAS:L-Threonolactone is a Carbohydrate Derivative.Formula:C4H6O4Color and Shape:SolidMolecular weight:118.09Adenosine 2'-PEG-Biotin
CAS:Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.Formula:C26H40N8O8SColor and Shape:SolidMolecular weight:624.71MC-1-F2
CAS:MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity and inhibits cancer stem cell (CSC) properties and can be used to study prostate cancer.Formula:C37H46N16O2Purity:97.31% - 98.44%Color and Shape:SolidMolecular weight:746.87(R)-(+)-O-Demethylbuchenavianine
CAS:(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.402'-Azido-2'-deoxyuridine
CAS:2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Formula:C9H11N5O5Purity:98%Color and Shape:SolidMolecular weight:269.21Mirvetuximab soravtansine
CAS:Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancerPurity:6mg/ml - 95.52% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.76 kDaSB273005
CAS:SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Formula:C22H24F3N3O4Purity:99.58%Color and Shape:SolidMolecular weight:451.44E-982
CAS:E-982 is derived from the reference compound.Formula:C25H31NO6SPurity:98%Color and Shape:SolidMolecular weight:473.58RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formula:C19H17N3Color and Shape:SolidMolecular weight:287.363,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:98.49%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.06XL413
CAS:XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Formula:C14H12ClN3O2Purity:98.40% - 99.94%Color and Shape:SolidMolecular weight:289.72BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formula:C27H24F5N5O3Purity:98.14% - 99.42%Color and Shape:SolidMolecular weight:561.5Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formula:C22H36N2O5SPurity:99.83%Color and Shape:SolidMolecular weight:440.6Mps1-IN-1
CAS:Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )Formula:C28H33N5O4SPurity:99.55%Color and Shape:SolidMolecular weight:535.66TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purity:99.73%Color and Shape:SolidMolecular weight:547.96Ref: TM-T6039
1mg38.00€5mg80.00€1mL*10mM (DMSO)96.00€10mg120.00€25mg216.00€50mg354.00€100mg512.00€200mg727.00€GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Formula:C22H18F3N3O4SPurity:99.92%Color and Shape:SolidMolecular weight:477.46Rabacfosadine succinate
CAS:Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.Formula:C25H41N8O10PPurity:98%Color and Shape:SolidMolecular weight:644.623Aloisine B
CAS:Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.Formula:C15H14ClN3Purity:95.15%Color and Shape:SolidMolecular weight:271.74IACS-4759
CAS:IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Formula:C10H17N3O2Color and Shape:SolidMolecular weight:211.26BMH-22
CAS:BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C16H17N3Color and Shape:SolidMolecular weight:251.33DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Formula:C17H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:312.75HBV-IN-14
CAS:HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Formula:C22H21ClN2O5Color and Shape:SolidMolecular weight:428.87CDK2-IN-12
CAS:CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Formula:C20H17N9O2SColor and Shape:SolidMolecular weight:447.47BMS-986463
CAS:BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD). BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC).Formula:C32H33FN4O5Color and Shape:SolidMolecular weight:572.63IRE1α kinase-IN-9
CAS:IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.Formula:C24H24N2O6Purity:98%Color and Shape:SolidMolecular weight:436.46DHODH-IN-13
CAS:DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Formula:C10H6F3N3O3Purity:99.66%Color and Shape:SolidMolecular weight:273.17Type II topoisomerase inhibitor 1
CAS:Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).Formula:C18H15N3O4Color and Shape:SolidMolecular weight:337.33(S)-CR8
CAS:(S)-CR8 is an effective second-generation cyclin-dependent kinase inhibitor.Formula:C24H29N7OColor and Shape:SolidMolecular weight:431.53Ulecaciclib
CAS:Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).Formula:C25H33FN8SColor and Shape:SolidMolecular weight:496.65hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Formula:C18H19BrN4O2Purity:99.871%Color and Shape:SolidMolecular weight:403.27Ref: TM-T11025
500mgTo inquire1mg60.00€2mg88.00€5mg133.00€1mL*10mM (DMSO)142.00€10mg203.00€25mg335.00€50mg474.00€100mg623.00€Sibrafiban
CAS:Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.Formula:C20H28N4O6Color and Shape:SolidMolecular weight:420.46VRX-0466617
CAS:VRX-0466617 is a novel selective Chk2 inhibitor.Formula:C19H20BrN5O2SColor and Shape:SolidMolecular weight:462.36Cdc7-IN-13
CAS:Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].Formula:C18H20N4O2SColor and Shape:SolidMolecular weight:356.44Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Formula:C18H17N7O2SColor and Shape:SolidMolecular weight:395.44OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formula:C13H14N4O3SColor and Shape:SolidMolecular weight:306.34
