Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(112 products)
- CDK(528 products)
- Cell Cycle Arrest(5 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(180 products)
- Integrin(262 products)
- Kinesin(87 products)
- LIM Kinase(19 products)
- Microtubule Associated(283 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(66 products)
- Rho(3 products)
- Wee1(14 products)
- c-Myc(77 products)
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Found 3786 products of "Cell Cycle/Checkpoint"
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MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formula:C17H25F2N3O5Purity:98.82%Color and Shape:SolidMolecular weight:389.39Ref: TM-T4061
1mg38.00€5mg84.00€10mg117.00€25mg226.00€50mg338.00€100mg467.00€200mg615.00€1mL*10mM (DMSO)99.00€Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32Ref: TM-T5673
1mg34.00€5mg73.00€10mg94.00€25mg177.00€50mg323.00€100mg460.00€200mg622.00€1mL*10mM (DMSO)71.00€Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formula:C18H18N4O3S2Purity:97.96% - 99.42%Color and Shape:SolidMolecular weight:402.49Y16 acetate(429653-73-6 free base)
Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoAFormula:C51H74N14O13Purity:98%Color and Shape:SolidMolecular weight:1091.24A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4Ref: TM-T2254
2mg44.00€5mg52.00€10mg81.00€25mg160.00€50mg271.00€100mg532.00€500mg1,169.00€1mL*10mM (DMSO)71.00€GW406108X(Z/E)
CAS:GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21Ref: TM-T9207L
1mg131.00€5mg286.00€10mg430.00€25mg647.00€50mg969.00€100mg1,301.00€1mL*10mM (DMSO)283.00€Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5524
1mg70.00€2mg95.00€5mg160.00€10mg250.00€25mg424.00€50mg612.00€100mg842.00€200mg1,159.00€1mL*10mM (DMSO)170.00€TR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33Ref: TM-T5310
1mg52.00€5mg104.00€10mg160.00€25mg259.00€50mg373.00€100mg518.00€200mg740.00€1mL*10mM (DMSO)107.00€LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.022′-Deoxy-2′-fluoroguanosine
CAS:2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).Formula:C10H12FN5O4Purity:99.89%Color and Shape:SolidMolecular weight:285.23BMS-5
CAS:BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formula:C17H14Cl2F2N4OSPurity:98.01% - 99.88%Color and Shape:SolidMolecular weight:431.29Ref: TM-T4598
1mg43.00€2mg55.00€5mg84.00€10mg123.00€25mg198.00€50mg298.00€100mg444.00€1mL*10mM (DMSO)92.00€BMS-1001
CAS:BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formula:C35H34N2O7Purity:98.43%Color and Shape:SolidMolecular weight:594.7Ref: TM-T8470
1mg62.00€5mg131.00€10mg187.00€25mg316.00€50mg447.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)182.00€Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53Atuveciclib
CAS:Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Formula:C18H18FN5O2SPurity:98.8%Color and Shape:SolidMolecular weight:387.43Ref: TM-T10464L
1mg88.00€2mg120.00€5mg202.00€10mg329.00€25mg612.00€50mg817.00€100mg1,121.00€1mL*10mM (DMSO)224.00€Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4Silver sulfadiazine
CAS:Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.Formula:C10H9AgN4O2SPurity:99.04% - 99.58%Color and Shape:SolidMolecular weight:357.14Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34
