
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(70 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
Show 10 more subcategories
Found 3477 products of "Cell Cycle/Checkpoint"
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DENV-IN-2
CAS:<p>DENV-IN-2 inhibits dengue virus replication (EC50: 0.016 nM), affects all serotypes (EC50: 0.013-0.029 nM). Derived from WO2018215315A1 6AB.</p>Formula:C29H26ClF3N2O6Color and Shape:SolidMolecular weight:590.98TMX-2138
CAS:<p>TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.</p>Formula:C40H43BrFN9O11SColor and Shape:SolidMolecular weight:956.791Uridine triphosphate 13C9,15N2 sodium
CAS:<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Formula:C9H1415N2NaO15P3Color and Shape:SolidMolecular weight:517.04Activated Protein C (390-404), human TFA
<p>APC's 390-404 peptide region key to anticoagulation, binds antibodies/proteins, inactivates cofactors Va/VIIIa.</p>Formula:C93H131F3N22O25Purity:98%Color and Shape:SolidMolecular weight:2014.165-Caroxy uracil-1-yl acetic acid benzyl ester
<p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Formula:C14H12N2O6Color and Shape:SolidMolecular weight:304.25Etrolizumab
CAS:<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Purity:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:LiquidBesufetamig
CAS:<p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>Color and Shape:Liquid2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Formula:C10H14N5Na2O8PColor and Shape:SolidMolecular weight:409.202DSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Color and Shape:Odour SolidCDK9-IN-25
<p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>Formula:C15H16FN5Purity:98%Color and Shape:SolidMolecular weight:285.32Risuteganib
CAS:<p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>Formula:C22H39N9O11SPurity:98%Color and Shape:SolidMolecular weight:637.66TH1085
CAS:<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Formula:C17H21N3Purity:99.99%Color and Shape:SolidMolecular weight:267.37DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Formula:C24H25FN4O3Purity:99.64%Color and Shape:SolidMolecular weight:436.487-TFA-ap-7-Deaza-ddG
CAS:<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Formula:C16H16F3N5O4Color and Shape:SolidMolecular weight:399.33Cotylenin A
CAS:<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Formula:C33H50O11Color and Shape:SolidMolecular weight:622.744Erythromycin A dihydrate
CAS:<p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>Formula:C37H69NO14Color and Shape:SolidMolecular weight:751.94CDK2-IN-7
CAS:<p>CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).</p>Formula:C24H30N6O4SColor and Shape:SolidMolecular weight:498.6wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Color and Shape:Odour SolidEmicoron
CAS:<p>Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.</p>Formula:C52H58N6O4Purity:98%Color and Shape:SolidMolecular weight:831.055'-DMT-3'-TBDMS-Bz-rA
CAS:<p>5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modification effects.</p>Formula:C44H49N5O7SiColor and Shape:SolidMolecular weight:787.975-O-benzoyl-1,2-O-isopropylidene-α-D-erythro-pent-3-ulofuranose
CAS:<p>5-O-benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is a Carbohydrate; Used for modified nucleoside.</p>Formula:C15H16O6Color and Shape:SolidMolecular weight:292.282',3'-Dideoxy-3'-fluorouridine
CAS:<p>Nucleoside Derivatives - 2’,3’-Dideoxy nucleosides, Fluoro-modified nucleosides, 3’-Modified nucleosides; Drugs and Inhibitors; Anti-HIV agent</p>Formula:C9H11FN2O4Color and Shape:SolidMolecular weight:230.193'-O-(2-Azidoethyl)adenosine
<p>Nucleoside Derivatives - 3’-Modified nucleosides; Azido-nucleosides</p>Color and Shape:Soild3'-O-t-Bulyldimethylsilyl thymidine
CAS:<p>Nucleosides - 2’-deoxynucleoside</p>Formula:C16H28N2O5SiColor and Shape:SolidMolecular weight:356.492'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine
CAS:<p>2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; Fluoro-modified nucleoside; Arabino nucleoside.</p>Formula:C8H10FN3O5Color and Shape:SolidMolecular weight:247.18N6-Acetyl adenosine
CAS:<p>Nucleoside Derivatives –Naturally modified ribo-nucleosides;Other modified nucleosides</p>Formula:C12H15N5O5Color and Shape:SolidMolecular weight:309.28N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine
<p>N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine is a Nucleoside Derivative - 2'-Modified nucleoside, N-Methylated/alkylated nucleoside, Fluoro-modified nucleoside.</p>Color and Shape:Soild2'-O-(2-Methoxyethyl) inosine
CAS:<p>2'-O-(2-Methoxyethyl) inosine is a Nucleoside Derivative - 2'-Modified nucleoside.</p>Formula:C13H18N4O6Color and Shape:SolidMolecular weight:326.312'-O-Acetyl-3'-azido-5'-O-(p-Toluoyl))-3'-deoxyuridine
CAS:<p>Nucleoside Derivatives - 3’-Modified nucleoside, Azido-nucleosides</p>Formula:C19H19N5O7Color and Shape:SolidMolecular weight:429.382'-β-C-Methyl inosine
CAS:<p>2'-beta-C-Methyl inosine (2'-C-Methyl inosine) is an HCV RNA polymerase inhibitor with antiviral activity and may be used in studies to treat hcv infections.</p>Formula:C11H14N4O5Color and Shape:SolidMolecular weight:282.252'-Deoxy-5,N4-dimethylcytidine
CAS:<p>2'-Deoxy-5,N4-dimethylcytidine is a Nucleoside Derivative - N-Methylated nucleoside.</p>Formula:C11H17N3O4Color and Shape:SolidMolecular weight:255.275-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
CAS:<p>Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides</p>Formula:C39H39NO5Color and Shape:SolidMolecular weight:601.736-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
CAS:<p>6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a Nucleoside Derivative - Other modified nucleoside.</p>Formula:C10H13N5O3Color and Shape:SolidMolecular weight:251.248-Nitroguanosine
CAS:<p>8-Nitroguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.</p>Formula:C10H12N6O7Color and Shape:SolidMolecular weight:328.243'-deoxy-3'-fluoro-β-D-xylo-inosine
CAS:<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 3’-Modified nucleosides; Xylo-nucleosides</p>Formula:C10H11FN4O4Color and Shape:SolidMolecular weight:270.222'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine
CAS:<p>2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-</p>Formula:C19H18F2N2O7Color and Shape:SolidMolecular weight:424.352'-Deoxy-2'-fluoro-5-hydroxymethyl arabinouridine
CAS:<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 2’-Modified nucleosides; 5-Modified pyrimidine nucleosides; Metabolite of FMAU</p>Formula:C10H13FN2O6Color and Shape:SolidMolecular weight:276.222'-Deoxy-6-azauridine
CAS:<p>2’-Deoxy-6-azauridine is a useful organic compound for research related to life sciences. The catalog number is TNU1081 and the CAS number is 20500-29-2.</p>Formula:C8H11N3O5Color and Shape:SolidMolecular weight:229.192',3',5'-Tri-O-Benzoyl-4'-thiouridine
CAS:<p>2',3',5'-Tri-O-Benzoyl-4'-thiouridine is a Thio-nucleoside.</p>Formula:C30H24N2O8SColor and Shape:SolidMolecular weight:572.593'-O-t-Butyldimethylsilyl adenosine
CAS:<p>3'-O-t-Butyldimethylsilyl adenosine is a Nucleoside; Used for special nucleoside modification.</p>Formula:C16H27N5O4SiColor and Shape:SolidMolecular weight:381.56-Deoxo-8-oxo-3'-deoxy-guanosine
<p>6-Deoxo-8-oxo-3’-deoxy-guanosine is a useful organic compound for research related to life sciences and the catalog number is TNU1451.</p>Color and Shape:Soild(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
CAS:<p>(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a Nucleoside Derivative - C-nucleoside; Fluoro-modified nucleoside.</p>Formula:C11H12F2O4Color and Shape:SolidMolecular weight:246.21DMTr-LNA-G(iBu)-3'-CED-phosphoramidite
CAS:<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phosphoramidites</p>Formula:C45H54N7O9PColor and Shape:SolidMolecular weight:867.935-(Aminomethyl)-2-thiouridine
CAS:<p>Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Amino nucleosides; Naturally modified ribo-nucleosides</p>Formula:C10H15N3O5SColor and Shape:SolidMolecular weight:289.31N6-Methyl-xylo-adenosine
CAS:<p>N6-Methyl-xylo-adenosine is a Nucleoside Derivative - Xylo-nucleoside;6-Substituted purine nucleoside.</p>Formula:C11H15N5O4Color and Shape:SolidMolecular weight:281.272-Deoxy-2'-deoxyuridine
CAS:<p>2-Deoxy-2'-deoxyuridine is a Nucleoside Derivative - 2-Deoxy uridine.</p>Formula:C9H12N2O4Color and Shape:SolidMolecular weight:212.22-Methoxy-2'-deoxyadenosine
CAS:<p>2-Methoxy-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Formula:C11H15N5O4Color and Shape:SolidMolecular weight:281.272'-Deoxy-2'-iodouridine
CAS:<p>2'-Deoxy-2'-iodouridine is a Halo-nucleoside.</p>Formula:C9H11IN2O5Color and Shape:SolidMolecular weight:354.1DHPS-IN-1
CAS:<p>DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.</p>Formula:C17H13BrClN3O2Color and Shape:SolidMolecular weight:406.668-Chloroguanosine
CAS:<p>8-Chloroguanosine is a Nucleoside Derivative - Halo-nucleoside, 8-Modified purine nucleoside.</p>Formula:C10H12ClN5O5Color and Shape:SolidMolecular weight:317.69

