Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(545 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(248 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(273 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3857 products of "Cell Cycle/Checkpoint"
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Isoindigotin
CAS:Isoindigotin is used in the therapy of Y.
Formula:C16H10N2O2Purity:98.14% - ≥95%Color and Shape:SolidMolecular weight:262.26Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Formula:C31H35Cl3N8O5Purity:99.69%Color and Shape:SolidMolecular weight:706.026-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Formula:C10H12N4O4SPurity:97.74%Color and Shape:SolidMolecular weight:284.29CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formula:C23H21ClN2O3Purity:98.82% - 99.50%Color and Shape:SolidMolecular weight:408.88RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formula:C14H11Cl3N2O3Purity:99.3% - 99.62%Color and Shape:SolidMolecular weight:361.61TMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Formula:C72H66N8O12S4Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:1363.6Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormula:C31H32N8O5Purity:98%Color and Shape:SolidMolecular weight:596.64Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formula:C27H32N8O2Purity:98.65% - 99.86%Color and Shape:SolidMolecular weight:500.6Ref: TM-T2077
5mg46.00€10mg66.00€25mg81.00€50mg96.00€100mg110.00€200mg161.00€500mg260.00€1mL*10mM (DMSO)49.00€CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formula:C14H12N6O2SPurity:99.54%Color and Shape:SolidMolecular weight:328.35Ref: TM-T9615
1mg52.00€5mg120.00€10mg187.00€25mg376.00€50mg588.00€100mg905.00€200mg1,216.00€1mL*10mM (DMSO)133.00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purity:98.68% - 99.77%Color and Shape:SolidMolecular weight:385.85Ref: TM-T4321
1mg34.00€2mg43.00€5mg63.00€10mg88.00€25mg130.00€50mg198.00€100mg298.00€1mL*10mM (DMSO)69.00€Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurity:98.68% - 99.64%Color and Shape:SolidMolecular weight:401.46Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formula:C27H35F2N7O3Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:543.61HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purity:98.26% - 99.83%Color and Shape:SolidMolecular weight:473.88Ref: TM-T8842
1mg138.00€5mg295.00€10mg505.00€25mg733.00€50mg888.00€100mg1,251.00€1mL*10mM (DMSO)309.00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:>99.99%Color and Shape:SolidMolecular weight:405.24Ref: TM-T8378
1mg124.00€2mg170.00€5mg260.00€10mg409.00€25mg677.00€50mg954.00€100mg1,288.00€1mL*10mM (DMSO)286.00€BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Formula:C16H14N2Purity:97.81%Color and Shape:SolidMolecular weight:234.3RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Formula:C23H20N6O3Purity:99.04% - 99.72%Color and Shape:SolidMolecular weight:428.44T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53Ref: TM-T5416
1mg48.00€5mg96.00€10mg144.00€25mg254.00€50mg424.00€100mg627.00€200mg998.00€1mL*10mM (DMSO)107.00€Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34
