Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(545 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(249 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3858 products of "Cell Cycle/Checkpoint"
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2'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formula:C10H12FN5O3Purity:99.95%Color and Shape:SolidMolecular weight:269.23ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.32BRD32048
CAS:BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.
Formula:C16H22N6OPurity:99.87%Color and Shape:SolidMolecular weight:314.39Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formula:C20H25ClN6O3Purity:98.95%Color and Shape:SolidMolecular weight:432.9Ref: TM-T7167
1mg34.00€2mg46.00€5mg67.00€10mg90.00€25mg130.00€50mg203.00€100mg305.00€200mg447.00€1mL*10mM (DMSO)75.00€Garenoxacin mesylate hydrate
CAS:Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strainsFormula:C23H20F2N2O4·CH4O3S·H2OPurity:99.56%Color and Shape:SolidMolecular weight:540.53YKL-5-124
CAS:YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displaysFormula:C28H33N7O3Purity:99.36%Color and Shape:SolidMolecular weight:515.61Ref: TM-T22461
1mg96.00€2mg135.00€5mg188.00€10mg341.00€25mg548.00€50mg782.00€100mg1,035.00€1mL*10mM (DMSO)225.00€BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99Ref: TM-T6162
1mg37.00€2mg52.00€5mg79.00€10mg116.00€25mg250.00€50mg416.00€100mg645.00€200mgTo inquire1mL*10mM (DMSO)87.00€Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.341,7-Diaminoheptane
CAS:1,7-Diaminoheptane, an aliphatic amine, is used in peptide synthesis and as a substrate, ligand, or reagent.Formula:C7H18N2Purity:99.97%Color and Shape:White To Light Yellow Crystalline ChunksMolecular weight:130.23Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purity:97.1% - 99.33%Color and Shape:SolidMolecular weight:558.70Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Formula:C26H32ClN7O4SColor and Shape:SolidMolecular weight:574.09PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Formula:C20H27N5O3Purity:99.85%Color and Shape:SolidMolecular weight:385.46Fasudil dihydrochloride
CAS:Fasudil dihydrochloride inhibits ROCK1/2, PKA, PKC, PKG, and acts as a Ca²⁺ channel blocker and vasodilator, supporting vascular, cardiovascular, and signaling research.Formula:C14H19Cl2N3O2SPurity:99.86%Color and Shape:SolidMolecular weight:364.29A-286982
CAS:A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55Ref: TM-T21781
1mg35.00€2mg50.00€5mg74.00€10mg107.00€25mg210.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)81.00€Nemorubicin
CAS:Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.
Formula:C32H37NO13Purity:97.4%Color and Shape:SolidMolecular weight:643.64Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formula:C27H20ClFN4O4Purity:98.31% - >99.99%Color and Shape:SolidMolecular weight:518.92Ref: TM-T2241
5mg52.00€10mg92.00€25mg146.00€50mg215.00€100mg334.00€200mg430.00€500mg705.00€1mL*10mM (DMSO)59.00€Chroman 1 dihydrochloride
Chroman 1 dihydrochloride: potent ROCK2 inhibitor (IC50: 1 pM), also affects ROCK1 (52 pM) and MRCK (150 nM).Formula:C24H30Cl2N4O4Color and Shape:SolidMolecular weight:509.43CWHM-12
CAS:CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).Formula:C26H32BrN5O6Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:590.47Ref: TM-TQ0250
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg221.00€50mg369.00€100mg550.00€1mL*10mM (DMSO)96.00€
