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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3749 products of "Cell Cycle/Checkpoint"

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  • Erythromycin thiocyanate

    CAS:
    Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.
    Formula:C38H68N2O13S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:793.02
  • CBP501 Affinity Peptide

    CAS:
    CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].
    Formula:C68H119N21O25S
    Color and Shape:Solid
    Molecular weight:1662.86
  • UnyLinker 12 TEA


    UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655
  • CD532 hydrochloride


    CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.
    Color and Shape:Solid
  • CDK12/13-IN-2


    CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12 and CDK13, exhibiting IC50 values of 15.5 nM and 12.2 nM, respectively. It effectively inhibits the proliferation of breast cancer cells and can be utilized in the research of triple-negative breast cancer.
    Formula:C24H22FN7O2
    Color and Shape:Solid
    Molecular weight:459.48
  • FF-10502

    CAS:
    FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.
    Formula:C9H12FN3O3S
    Color and Shape:Solid
    Molecular weight:261.27
  • Fibronectin CS1 Peptide

    CAS:
    Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.
    Formula:C38H64N8O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:872.96
  • Fuzapladib

    CAS:
    <p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>
    Formula:C15H20F3N3O3S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:379.4
  • Carboxy pyridostatin trifluoroacetate salt


    Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.
    Formula:C37H35F3N10O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:820.73
  • L82-G17

    CAS:
    <p>L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.</p>
    Formula:C11H9ClN4O2
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:264.67
  • CCT241533 dihydrochloride

    CAS:
    Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.
    Formula:C23H29Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:515.41
  • Censavudine

    CAS:
    <p>Censavudine (OBP-601) is an HIV-1/2 treatment and prevention drug, a reverse transcriptase inhibitor with EC50 of 30-890 nM.</p>
    Formula:C12H12N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.23
  • DHFR-IN-11


    DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.
    Color and Shape:Odour Solid
  • Apcin A HCL

    CAS:
    <p>Apcin A HCL is an Apcin-derived APC inhibitor that binds Cdc20 and hinders ubiquitination, useful for synthesizing PROTAC CP5V.</p>
    Formula:C10H15Cl4N5O2
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:379.07
  • dCeMM3 

    CAS:
    <p>dCeMM3 is a glue degrader that induces ubiquitination and degradation of cyclin K by promoting CDK12-cyclin K interaction with CRL4B ligase.</p>
    Formula:C14H11ClN4OS
    Purity:98.48% - 99.41%
    Color and Shape:Solid
    Molecular weight:318.78
  • Filanesib TFA

    CAS:
    <p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>
    Formula:C22H23F5N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.5
  • RA-V


    RA-V is a natural product that can be used as a reference standard.
    Formula:C160H202N24O41
    Color and Shape:Solid
    Molecular weight:3117.5
  • EC0488

    CAS:
    <p>EC0488 was used to synthesize EC0531, which has folic acid receptor specificity and anti-tumor activity.</p>
    Formula:C65H98N16O34S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1679.63
  • GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Formula:C22H37N9O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.58
  • Bz-rC Phosphoramidite

    CAS:
    <p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C52H66N5O9PSi
    Color and Shape:Solid
    Molecular weight:964.185