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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 2897 products for "Cell Cycle/Checkpoint".

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  • Rifaximin

    CAS:
    Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.
    Formula:C43H51N3O11
    Purity:99.18% - 99.40%
    Color and Shape:Solid
    Molecular weight:785.8785
  • hSMG-1 inhibitor 11j

    CAS:
    hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.
    Formula:C27H28ClN7O3S
    Purity:99.22% - 99.69%
    Color and Shape:Yellow Solid
    Molecular weight:566.074
  • MF-094

    CAS:
    MF-094 is a selective USP30 inhibitor with IC50 of 0.12 μM. MF-094 can increase protein ubiquitination and accelerate mitophagy.Cost-effective and quality-assured.
    Formula:C30H37N3O4S
    Purity:99.93%
    Color and Shape:White Solid
    Molecular weight:535.697
  • Fuzapladib

    CAS:
    Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.
    Formula:C15H20F3N3O3S
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:379.398
  • CDK2-IN-4

    CAS:
    CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.
    Formula:C23H18N6O2S
    Purity:97.24% - 99.10%
    Color and Shape:Solid
    Molecular weight:442.493
  • BT173

    CAS:
    BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.
    Formula:C18H12BrN3O2
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:382.211
  • SU056

    CAS:
    SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.
    Formula:C20H16FNO5
    Purity:99.89%
    Color and Shape:Yellow Solid
    Molecular weight:369.3431
  • Lerociclib dihydrochloride

    CAS:
    Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/
    Formula:C26H36Cl2N8O
    Purity:97.4%
    Color and Shape:Solid
    Molecular weight:547.523
  • Carmofur

    CAS:
    Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.
    Formula:C11H16FN3O3
    Purity:98.53% - 99.98%
    Color and Shape:Solid
    Molecular weight:257.2614
  • Hu7691 free base

    CAS:
    Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.
    Formula:C22H21F3N4O
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:414.423
  • Hycanthone

    CAS:
    Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.
    Formula:C20H24N2O2S
    Purity:98.78%
    Color and Shape:Yellow-Orange Powder (Ntp 1992)
    Molecular weight:356.482
  • R-10015

    CAS:
    R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.
    Formula:C20H19ClN6O2
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:410.857
  • JH-RE-06

    CAS:
    JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.
    Formula:C20H16Cl3N3O4
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:468.718
  • Rifapentine

    CAS:
    Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.
    Formula:C47H64N4O12
    Purity:95.74% - ≥98%
    Color and Shape:Solid
    Molecular weight:877.03
  • Mps1-IN-3

    CAS:
    Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
    Formula:C26H31N7O4S
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:537.634
  • NMDI14

    CAS:
    NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).
    Formula:C21H25N3O4S
    Purity:97.79% - 99.37%
    Color and Shape:Solid
    Molecular weight:415.506
  • DNA2 inhibitor C5

    CAS:
    DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.
    Formula:C10H6N2O5
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:234.165
  • N-Dodecyl-β-D-maltoside

    CAS:
    N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the
    Formula:C24H46O11
    Purity:99.18% - >99.99%
    Color and Shape:White Powder
    Molecular weight:510.62
  • GSK-1520489A

    CAS:
    GSK-1520489A is an active PKMYT1 inhibitor.
    Formula:C21H23N5O3S
    Purity:99.85%
    Color and Shape:White Solid
    Molecular weight:425.5
  • GSK-3 inhibitor 4

    CAS:
    Orally active GSK-3 inhibitor 4 targets GSK-3α/β, CDK2/5 (IC50: 0.45-0.68 μM) and may aid in Alzheimer's research by lowering Tau protein.
    Formula:C22H15F2N5O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:403.38