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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 2896 products for "Cell Cycle/Checkpoint".

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  • GSK-626616

    CAS:
    GSK-626616: strong, oral DYRK3 inhibitor (IC50: 0.7 nM), affects DYRK family, may treat anemia.
    Formula:C18H10Cl2N4OS
    Purity:98.27%
    Color and Shape:Solid
    Molecular weight:401.269
  • BAY-2402234

    CAS:
    BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.
    Formula:C21H18ClF5N4O4
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:520.837
  • Ribociclib succinate

    CAS:
    Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).
    Formula:C27H36N8O5
    Purity:99.90%
    Color and Shape:White Solid
    Molecular weight:552.6253
  • XPW1

    CAS:
    XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.
    Formula:C36H39ClFN7O2
    Purity:99.63%
    Color and Shape:White Solid
    Molecular weight:656.19
  • Gemifloxacin mesylate

    CAS:
    Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually
    Formula:C19H24FN5O7S
    Purity:97.24% - ≥95%
    Color and Shape:Beige Solid
    Molecular weight:485.487
  • Enrofloxacin

    CAS:
    Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
    Formula:C19H22FN3O3
    Purity:99.43% - >99.99%
    Color and Shape:White Solid
    Molecular weight:359.3947
  • NU6140

    CAS:
    NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).
    Formula:C23H30N6O2
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:422.5233
  • TAK-901

    CAS:
    TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others
    Formula:C28H32N4O3S
    Purity:99.02% - 99.59%
    Color and Shape:Yellow Solid
    Molecular weight:504.644
  • HS-243

    CAS:
    HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
    Formula:C17H16N4O3
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:324.3339
  • Cirtuvivint

    CAS:
    Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.
    Formula:C24H25N7O
    Purity:99.95% - 99.96%
    Color and Shape:Yellow Solid
    Molecular weight:427.5016
  • Cinoxacin

    CAS:
    Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.
    Formula:C12H10N2O5
    Purity:99.62% - 99.98%
    Color and Shape:White Solid
    Molecular weight:262.2182
  • Cyclin K degrader 1


    Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.
    Formula:C23H17Cl2N5O2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:466.32
  • hSMG-1 inhibitor 11j

    CAS:
    hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.
    Formula:C27H28ClN7O3S
    Purity:99.22% - 99.69%
    Color and Shape:Yellow Solid
    Molecular weight:566.074
  • MF-094

    CAS:
    MF-094 is a selective USP30 inhibitor with IC50 of 0.12 μM. MF-094 can increase protein ubiquitination and accelerate mitophagy.Cost-effective and quality-assured.
    Formula:C30H37N3O4S
    Purity:99.93%
    Color and Shape:White Solid
    Molecular weight:535.697
  • Fuzapladib

    CAS:
    Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.
    Formula:C15H20F3N3O3S
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:379.398
  • Levofloxacin hydrate

    CAS:
    Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.
    Formula:C18H20FN3O4H2O
    Purity:98.26%
    Color and Shape:White Solid
    Molecular weight:370.38
  • TAO Kinase inhibitor 2

    CAS:
    TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
    Formula:C25H24N2O3
    Purity:98.58%
    Color and Shape:Solid
    Molecular weight:400.4697
  • Metarrestin

    CAS:
    Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
    Formula:C31H30N4O
    Purity:99.45%
    Color and Shape:White Solid
    Molecular weight:474.5961
  • Nedaplatin

    CAS:
    Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.
    Formula:C2H8N2O3Pt
    Purity:99.88% - >99.99%
    Color and Shape:Solid
    Molecular weight:303.181
  • P 218

    CAS:
    P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.
    Formula:C18H25ClN4O4
    Purity:99.93%
    Color and Shape:White Solid
    Molecular weight:396.87