Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3685 products of "Cell Cycle/Checkpoint"

Purity (%)

100

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MYCi975
CAS:
- 2289691-01-4
MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.
Formula:C₂₅H₁₆Cl₂F₆N₂O₂
Purity:99.3% - 99.82%
Color and Shape:Solid
Molecular weight:561.3
Ref: TM-T12133
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Vitamin D2
CAS:
- 50-14-6
Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.
Formula:C₂₈H₄₄O
Purity:98.73% - 99.89%
Color and Shape:Prisms From Acetone 1998)
Molecular weight:396.65
Ref: TM-T1086
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R-10015
CAS:
- 2097938-51-5
R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.
Formula:C₂₀H₁₉ClN₆O₂
Purity:98.68%
Color and Shape:Solid
Molecular weight:410.86
Ref: TM-T12609
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Abciximab
CAS:
- 143653-53-6
Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.
Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%
Color and Shape:Liquid
Molecular weight:95.18 kDa
Ref: TM-T76844
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Efalizumab
CAS:
- 214745-43-4
Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.
Purity:SDS-PAGE:95% SEC-HPLC:98.77%
Color and Shape:Liquid
Molecular weight:146.14 kDa
Ref: TM-T76924
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Cirtuvivint
CAS:
- 2143917-62-6
Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.
Formula:C₂₄H₂₅N₇O
Purity:99.46% - >99.99%
Color and Shape:Solid
Molecular weight:427.5
Ref: TM-T39608
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Centrinone
CAS:
- 1798871-30-3
Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).
Formula:C₂₆H₂₅F₂N₇O₆S₂
Purity:98.76%
Color and Shape:Solid
Molecular weight:633.65
Ref: TM-T14927
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SU056
CAS:
- 2376580-08-2
SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.
Formula:C₂₀H₁₆FNO₅
Purity:99.89%
Color and Shape:Soild
Molecular weight:369.34
Ref: TM-T67741
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DI-87
CAS:
- 2107280-55-5
DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.
Formula:C₂₃H₃₀N₆O₃S₂
Purity:99.76%
Color and Shape:Solid
Molecular weight:502.65
Ref: TM-T39550
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Monalizumab
CAS:
- 1228763-95-8
Monalizumab, a humanized antibody, enhances NK cell function by inhibiting NKG2A; used in HNSCC studies.
Purity:95% - >95.0% (SDS-PAGE); 100% (SEC-HPLC)
Color and Shape:Liquid
Molecular weight:147 kDa (average)
Ref: TM-T76691
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Metarrestin
CAS:
- 1443414-10-5
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
Formula:C₃₁H₃₀N₄O
Purity:99.45%
Color and Shape:Solid
Molecular weight:474.6
Ref: TM-T12006
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6-Mercaptopurine
CAS:
- 50-44-2
6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.
Formula:C₅H₄N₄S
Purity:99.53% - 99.63%
Color and Shape:Yellow Crystalline Powder Solid
Molecular weight:152.18
Ref: TM-T0010
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N-Dodecyl-β-D-maltoside
CAS:
- 69227-93-6
N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the
Formula:C₂₄H₄₆O₁₁
Purity:99.18% - >99.99%
Color and Shape:White Powder
Molecular weight:510.62
Ref: TM-T16223
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MALAT1-IN-1
CAS:
- 827327-28-6
MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.
Formula:C₁₉H₂₁N₃O₂
Purity:99.58%
Color and Shape:Solid
Molecular weight:323.39
Ref: TM-T16007
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CDK2-IN-4
CAS:
- 2079895-42-2
CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.
Formula:C₂₃H₁₈N₆O₂S
Purity:97.24% - 99.10%
Color and Shape:Solid
Molecular weight:442.49
Ref: TM-T14916
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Ribavirin
CAS:
- 36791-04-5
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
Formula:C₈H₁₂N₄O₅
Purity:99.09% - 99.83%
Color and Shape:Less Solid Colourless Solid
Molecular weight:244.20
Ref: TM-T0684
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PTBP1-RNA-binding inhibitor P6 TFA
PTBP1-RNA-binding inhibitor P6 TFA is a stapled peptide inhibitor of PTBP1, used to inhibit RNA alternative splicing events regulated by PTBP1.
Color and Shape:Odour Solid
Ref: TM-T81356
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Ca2+ channel agonist 1
CAS:
- 1402821-24-2
Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.
Formula:C₁₉H₂₆N₆O
Purity:97.71%
Color and Shape:Solid
Molecular weight:354.45
Ref: TM-T10659
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Tinengotinib
CAS:
- 2230490-29-4
Tinengotinib is a multikinase inhibitor that targets a series of kinases , including Aurora kinases A/B, JAK1/2, FGFR1/2/3, VEGFRs, and many other kinases.
Formula:C₂₀H₁₉ClN₆O
Purity:99.05%
Color and Shape:Solid
Molecular weight:394.86
Ref: TM-T39718
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Enoxacin
CAS:
- 74011-58-8
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Formula:C₁₅H₁₇FN₄O₃
Purity:98.68% - 99.89%
Color and Shape:Off-White To Yellow Crystals
Molecular weight:320.32
Ref: TM-T0717L