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Ferroptosis

Ferroptosis

Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.

Found 215 products of "Ferroptosis"

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  • Ferroptosis-IN-16


    <p>Ferroptosis-IN-16 (Compound 13l) acts as a specific inhibitor of ferroptosis, demonstrating EC50 values of 0.7 nM in ES-2 cells and 0.9 nM in LX-2 cells. It effectively alleviates acute liver injury induced by Acetaminophen in mouse models and shows excellent metabolic stability in mouse liver microsomes.</p>
    Formula:C26H23N5O
    Color and Shape:Solid
    Molecular weight:421.49
  • W1131 TFA


    <p>W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.</p>
    Formula:C25H20F3N5O6
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:543.45
  • PRLX-93936 HCL

    CAS:
    <p>PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.</p>
    Formula:C21H26Cl2N4O2
    Purity:98.4% - 99.94%
    Color and Shape:Solid
    Molecular weight:437.37
  • 84-B10

    CAS:
    <p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>
    Formula:C25H22F3NO5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:473.44
  • CuATSM

    CAS:
    <p>Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.</p>
    Formula:C8H14CuN6S2
    Color and Shape:Solid
    Molecular weight:321.92
  • Idebenone

    CAS:
    Formula:C19H30O5
    Purity:>98.0%(T)(HPLC)
    Color and Shape:Light yellow to Brown powder to crystal
    Molecular weight:338.44

    Ref: 3B-I0848

    1g
    66.00€
    5g
    198.00€
    25g
    623.00€
  • CuATSP

    CAS:
    <p>CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.</p>
    Formula:C18H18CuN6S2
    Purity:97.09%
    Color and Shape:Solid
    Molecular weight:446.05
  • Cerivastatin sodium

    CAS:
    <p>Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.</p>
    Formula:C26H33FNNaO5
    Purity:98.50% - 99.67%
    Color and Shape:Solid
    Molecular weight:481.53
  • CCW16

    CAS:
    <p>CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.</p>
    Formula:C22H20ClNO3
    Purity:97%
    Color and Shape:Solid
    Molecular weight:381.85
  • Chrysosplenetin

    CAS:
    <p>Chrysosplenetin is a metabolic inhibitor of artemisinin.</p>
    Formula:C19H18O8
    Purity:97.43% - 98.4%
    Color and Shape:Solid
    Molecular weight:374.34
  • L-Glutamic acid monosodium salt

    CAS:
    <p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>
    Formula:C5H8NO4·Na
    Purity:99.93%
    Color and Shape:White Solid Crystalline
    Molecular weight:169.11
  • Piperlongumine

    CAS:
    <p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>
    Formula:C17H19NO5
    Purity:97.03% - 99.90%
    Color and Shape:Solid
    Molecular weight:317.34
  • NADPH tetracyclohexanamine

    CAS:
    <p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>
    Formula:C45H82N11O17P3
    Purity:98.73% - 99.05%
    Color and Shape:Solid
    Molecular weight:1142.12
  • L-BUTHIONINE-(S,R)-SULFOXIMINE

    CAS:
    <p>L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.</p>
    Formula:C8H18N2O3S
    Purity:97.07% - ≥98%
    Color and Shape:White Fine Powder
    Molecular weight:222.31
  • ML-210

    CAS:
    <p>ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.</p>
    Formula:C22H20Cl2N4O4
    Purity:97% - 99.03%
    Color and Shape:Solid
    Molecular weight:475.32
  • Piperazine Erastin

    CAS:
    <p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>
    Formula:C35H41ClN6O4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:645.19
  • RSL3

    CAS:
    <p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>
    Formula:C23H21ClN2O5
    Purity:98% - 99.96%
    Color and Shape:Solid
    Molecular weight:440.88
  • TBHQ

    CAS:
    <p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>
    Formula:C10H14O2
    Purity:99.17% - 99.53%
    Color and Shape:White Solid Powder
    Molecular weight:166.22
  • Trolox

    CAS:
    <p>Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.</p>
    Formula:C14H18O4
    Purity:98.90% - 99.90%
    Color and Shape:White To Fainly Beige Crystalline Powder
    Molecular weight:250.29
  • Alogliptin

    CAS:
    <p>Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of &lt;10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9</p>
    Formula:C18H21N5O2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:339.39
  • Alogliptin Benzoate

    CAS:
    <p>Alogliptin Benzoate, a potent DPP-4 inhibitor with &gt;10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>
    Formula:C25H27N5O4
    Purity:99.94% - >99.99%
    Color and Shape:White Powder
    Molecular weight:461.51
  • WITHAFERIN A

    CAS:
    <p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>
    Formula:C28H38O6
    Purity:97.41% - 99.99%
    Color and Shape:Solid
    Molecular weight:470.6
  • Bardoxolone Methyl

    CAS:
    <p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>
    Formula:C32H43NO4
    Purity:97.81% - 99.09%
    Color and Shape:Solid
    Molecular weight:505.69
  • Siramesine hydrochloride

    CAS:
    <p>Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit</p>
    Formula:C30H32ClFN2O
    Purity:99.72% - >99.99%
    Color and Shape:Solid
    Molecular weight:491.04
  • Necrostatin-1

    CAS:
    <p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>
    Formula:C13H13N3OS
    Purity:99.25% - >99.99%
    Color and Shape:Solid
    Molecular weight:259.33
  • JKE-1674

    CAS:
    <p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>
    Formula:C20H20Cl2N4O4
    Purity:98.02% - 98.4%
    Color and Shape:Solid
    Molecular weight:451.3
  • Bay 11-7085

    CAS:
    <p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>
    Formula:C13H15NO2S
    Purity:99.76% - 99.94%
    Color and Shape:White Solid
    Molecular weight:249.33
  • DL-Buthionine-(S,R)-sulfoximine

    CAS:
    <p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>
    Formula:C8H18N2O3S
    Purity:98% - 99.64%
    Color and Shape:White Fine Powder
    Molecular weight:222.31
  • Coenzyme Q10

    CAS:
    <p>Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.</p>
    Formula:C59H90O4
    Purity:99.14% - 99.88%
    Color and Shape:Drypowder
    Molecular weight:863.34
  • ML162

    CAS:
    <p>ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C23H22Cl2N2O3S
    Purity:98.42% - 99.55%
    Color and Shape:Solid
    Molecular weight:477.4
  • (E)-Ferulic acid

    CAS:
    <p>(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of</p>
    Formula:C10H10O4
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:194.18
  • D-glutamine

    CAS:
    <p>D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.</p>
    Formula:C5H10N2O3
    Purity:99.99%
    Color and Shape:White Or Off-White Powder
    Molecular weight:146.14
  • BAY 87-2243

    CAS:
    <p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>
    Formula:C26H26F3N7O2
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:525.53
  • L-Buthionine-(S,R)-sulfoximine hydrochloride


    <p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>
    Formula:C8H19ClN2O3S
    Color and Shape:Solid
    Molecular weight:258.77
  • Liproxstatin-1 hydrochloride

    CAS:
    <p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>
    Formula:C19H22Cl2N4
    Color and Shape:Solid
    Molecular weight:377.31
  • Pioglitazone potassium

    CAS:
    <p>Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.</p>
    Formula:C19H19KN2O3S
    Color and Shape:Solid
    Molecular weight:394.53
  • CDDO-Im

    CAS:
    <p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>
    Formula:C34H43N3O3
    Purity:98.3% - 99.61%
    Color and Shape:Solid
    Molecular weight:541.72
  • (-)-Epicatechin

    CAS:
    <p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>
    Formula:C15H14O6
    Purity:98.55% - 98.80%
    Color and Shape:Solid
    Molecular weight:290.27
  • UAMC-3203 hydrochloride

    CAS:
    <p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>
    Formula:C25H38ClN5O2S
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:508.12
  • Baicalein monohydrate

    CAS:
    <p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>
    Formula:C15H12O6
    Color and Shape:Solid
    Molecular weight:288.25
  • Ferrostatin-1

    CAS:
    <p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>
    Formula:C15H22N2O2
    Purity:96.1% - 99.68%
    Color and Shape:Solid
    Molecular weight:262.35
  • CIL56

    CAS:
    <p>CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).</p>
    Formula:C23H27N3O5S2
    Purity:99.46% - 99.91%
    Color and Shape:Solid
    Molecular weight:489.61
  • Hemin

    CAS:
    <p>Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.</p>
    Formula:C34H32ClFeN4O4
    Purity:97.169% - 99.59%
    Color and Shape:Dark Purple Crystalline Powder
    Molecular weight:651.94
  • DihydroarteMisinic acid

    CAS:
    <p>DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal</p>
    Formula:C15H24O2
    Purity:99.06% - 99.17%
    Color and Shape:Solid
    Molecular weight:236.35
  • Arteannuin B

    CAS:
    <p>1. Arteannuin B has potent antimalarial activity.</p>
    Formula:C15H20O3
    Purity:98% - 99.8%
    Color and Shape:Solid
    Molecular weight:248.32
  • Eprenetapopt

    CAS:
    <p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>
    Formula:C10H17NO3
    Purity:98.75% - 99.57%
    Color and Shape:Solid
    Molecular weight:199.25
  • DL-α-Tocopherol

    CAS:
    <p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>
    Formula:C29H50O2
    Purity:99.61% - 99.90%
    Color and Shape:Light Yellow Liquid Viscous
    Molecular weight:430.71
  • SRS11-92

    CAS:
    <p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>
    Formula:C22H28N2O2
    Purity:98.58%
    Color and Shape:Solid
    Molecular weight:352.47
  • Deferitrin

    CAS:
    <p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>
    Formula:C11H11NO4S
    Purity:98.71%
    Color and Shape:Solid
    Molecular weight:253.27
  • 1R,3S-RSL 3

    CAS:
    <p>1R,3S-RSL 3 is a harmala alkaloid.</p>
    Formula:C23H21ClN2O5
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:440.88
  • Setanaxib

    CAS:
    <p>Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.</p>
    Formula:C21H19ClN4O2
    Purity:93.468% - 99.31%
    Color and Shape:Solid
    Molecular weight:394.85
  • Dp44mT

    CAS:
    <p>Dp44mT, a effective iron chelator, has selective antitumor activity.</p>
    Formula:C14H15N5S
    Purity:99% - 99.02%
    Color and Shape:Solid
    Molecular weight:285.37
  • Nordihydroguaiaretic acid

    CAS:
    <p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>
    Formula:C18H22O4
    Purity:97.82% - 99.91%
    Color and Shape:Solid
    Molecular weight:302.36
  • NADPH tetrasodium salt

    CAS:
    <p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>
    Formula:C21H26N7Na4O17P3
    Purity:97.15% - >99.99%
    Color and Shape:Solid
    Molecular weight:833.35
  • Troglitazone

    CAS:
    <p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>
    Formula:C24H27NO5S
    Purity:98% - 99.8%
    Color and Shape:Yellow Solid
    Molecular weight:441.54
  • SRS16-86

    CAS:
    <p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>
    Formula:C26H32N4O2
    Purity:97.73%
    Color and Shape:Solid
    Molecular weight:432.56
  • Pseudolaric Acid B

    CAS:
    <p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>
    Formula:C23H28O8
    Purity:98.91% - 99.84%
    Color and Shape:Solid
    Molecular weight:432.46
  • Levobupivacaine

    CAS:
    <p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>
    Formula:C18H28N2O
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:288.43
  • Liproxstatin-1

    CAS:
    <p>Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).</p>
    Formula:C19H21ClN4
    Purity:97.11% - 99.44%
    Color and Shape:Solid
    Molecular weight:340.85
  • Rosiglitazone hydrochloride

    CAS:
    <p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>
    Formula:C18H19N3O3S·HCl
    Purity:99.63% - 99.79%
    Color and Shape:Solid
    Molecular weight:393.89
  • SP600125

    CAS:
    <p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>
    Formula:C14H8N2O
    Purity:97.63% - 99.82%
    Color and Shape:Solid
    Molecular weight:220.23
  • L-Cystine

    CAS:
    <p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>
    Formula:C6H12N2O4S2
    Purity:99.59% - 99.85%
    Color and Shape:White Solid Powder
    Molecular weight:240.30
  • Rosiglitazone

    CAS:
    <p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>
    Formula:C18H19N3O3S
    Purity:98.61% - 99.87%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:357.43
  • L-Glutamic acid

    CAS:
    <p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>
    Formula:C5H9NO4
    Purity:99.14% - 99.55%
    Color and Shape:White Solid Crystalline
    Molecular weight:147.13
  • ML385

    CAS:
    <p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>
    Formula:C29H25N3O4S
    Purity:98.08% - >99.99%
    Color and Shape:Solid
    Molecular weight:511.59
  • Trigonelline

    CAS:
    <p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>
    Formula:C7H7NO2
    Purity:97.585% - 99.49%
    Color and Shape:Prisms Aqueous From Alcohol + Water Solid
    Molecular weight:137.14
  • PRIMA-1

    CAS:
    <p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>
    Formula:C9H15NO3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:185.22
  • Atorvastatin hemicalcium salt

    CAS:
    <p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>
    Formula:C33H34FN2O5Ca
    Purity:99.27% - >99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:577.67
  • Erastin

    CAS:
    <p>Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!</p>
    Formula:C30H31ClN4O4
    Purity:98% - 99.75%
    Color and Shape:Solid
    Molecular weight:547.04
  • FIN56

    CAS:
    <p>FIN56 is a specific inducer of ferroptosis.</p>
    Formula:C25H31N3O5S2
    Purity:99.72% - 99.78%
    Color and Shape:Solid
    Molecular weight:517.66
  • PD146176

    CAS:
    <p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>
    Formula:C15H11NS
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:237.32
  • Pifithrin-α hydrobromide

    CAS:
    <p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>
    Formula:C16H18N2OS·HBr
    Purity:97.71% - >99.99%
    Color and Shape:Solid
    Molecular weight:367.3
  • Pifithrin-β hydrobromide

    CAS:
    <p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>
    Formula:C16H17BrN2S
    Purity:99.24% - 99.74%
    Color and Shape:Solid
    Molecular weight:349.29
  • Levobupivacaine hydrochloride

    CAS:
    <p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>
    Formula:C18H28N2O·HCl
    Purity:99.74%
    Color and Shape:White Crystalline Powder
    Molecular weight:324.89
  • Ammonium iron(III) citrate

    CAS:
    <p>Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.</p>
    Formula:C24H32Fe3N3O28
    Purity:98%
    Color and Shape:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of Ammonia
    Molecular weight:978.05
  • U-73122

    CAS:
    <p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>
    Formula:C29H40N2O3
    Purity:97.50%
    Color and Shape:Solid Off-White
    Molecular weight:464.64
  • UAMC-3203

    CAS:
    <p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>
    Formula:C25H37N5O2S
    Purity:97.052% - 99.72%
    Color and Shape:Solid
    Molecular weight:471.66
  • FINO2

    CAS:
    <p>FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.</p>
    Formula:C15H28O3
    Purity:97.27%
    Color and Shape:Soild
    Molecular weight:256.38
  • Microtubule inhibitor 8

    CAS:
    <p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>
    Formula:C21H15N3O2S
    Color and Shape:Solid
    Molecular weight:373.43
  • Pioglitazone-d4

    CAS:
    <p>Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .</p>
    Formula:C19H20N2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.46
  • W1131

    CAS:
    <p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>
    Formula:C23H19N5O4
    Color and Shape:Solid
    Molecular weight:429.43
  • YL-939


    <p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>
    Formula:C25H26N6O
    Color and Shape:Solid
    Molecular weight:426.51
  • Ferroptosis inducer-1

    CAS:
    <p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>
    Formula:C25H21ClN2O5
    Color and Shape:Solid
    Molecular weight:464.9
  • CN128 hydrochloride

    CAS:
    <p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>
    Formula:C15H18ClNO3
    Color and Shape:Solid
    Molecular weight:295.76
  • Anticancer agent 147

    CAS:
    <p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>
    Formula:C32H40BrN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:578.58
  • Tubulin inhibitor 30

    CAS:
    <p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>
    Formula:C22H19N3O5
    Color and Shape:Solid
    Molecular weight:405.4
  • IM-93

    CAS:
    <p>IM-93 inhibits ferroptosis and NETosis with an IC&lt; sub&gt;50 of 0.45 μM for cell death inhibition [1].</p>
    Formula:C21H28N4O2
    Color and Shape:Solid
    Molecular weight:368.47
  • CGP 65015

    CAS:
    <p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>
    Formula:C14H15NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:261.27
  • FA16


    <p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>
    Formula:C22H27F3N4O2S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:468.54
  • Deferitazole

    CAS:
    <p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>
    Formula:C18H25NO7S
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:399.46
  • Erastin2

    CAS:
    <p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>
    Formula:C36H35ClN4O4
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:623.14
  • HBED

    CAS:
    <p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>
    Formula:C20H24N2O6
    Purity:97.35% - 98.58%
    Color and Shape:Solid
    Molecular weight:388.41
  • BCP-T.A

    CAS:
    <p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>
    Formula:C23H19Cl2N3OS
    Purity:99.49%
    Color and Shape:Solid
    Molecular weight:456.39
  • Lepadin E

    CAS:
    <p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>
    Formula:C26H47NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.66
  • CP-24879 hydrochloride

    CAS:
    <p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>
    Formula:C11H18ClNO
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:215.72
  • Docebenone

    CAS:
    <p>Docebenone is a selective and orally active inhibitor of 5-LO.</p>
    Formula:C21H26O3
    Color and Shape:Solid
    Molecular weight:326.43
  • Ferroptocide

    CAS:
    <p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>
    Formula:C30H36ClN3O7
    Color and Shape:Solid
    Molecular weight:586.08
  • Ogremorphin

    CAS:
    <p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>
    Formula:C21H17N3OS
    Purity:99.65% - 99.65%
    Color and Shape:Solid
    Molecular weight:359.44
  • Lepadin H

    CAS:
    <p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>
    Formula:C26H45NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.64
  • viFSP1

    CAS:
    <p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>
    Formula:C16H17N3O3S
    Color and Shape:Solid
    Molecular weight:331.39