Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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Miltefosine
CAS:<p>Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.</p>Formula:C21H46NO4PPurity:98% - 99.87%Color and Shape:White To Off-White PowderMolecular weight:407.57Hydralazine hydrochloride
CAS:<p>Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.</p>Formula:C8H9ClN4Purity:99.85% - 99.86%Color and Shape:Yellow Crystals White Crystalline SolidMolecular weight:196.64MS417
CAS:<p>MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak</p>Formula:C20H19ClN4O2SPurity:99.87%Color and Shape:SolidMolecular weight:414.91A-485
CAS:<p>A-485 is a p300/CBP histone acetyltransferase (HAT) inhibitor that inhibits p300 and CBP. A-485 has antitumor effects. Cost effective and quality assured.</p>Formula:C25H24F4N4O5Purity:98.01% - 99.44%Color and Shape:SolidMolecular weight:536.48ZL0580
CAS:<p>ZL0580 suppresses HIV by blocking Tat activation, halting transcription, and promoting repressive chromatin at the HIV promoter.</p>Formula:C25H23F3N4O4SPurity:99.70%Color and Shape:SolidMolecular weight:532.53Brepocitinib P-Tosylate
CAS:<p>Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).</p>Formula:C25H29F2N7O4SPurity:99.82% - 99.97%Color and Shape:SolidMolecular weight:561.6Glucosamine hydrochloride
CAS:<p>Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.</p>Formula:C6H13NO5·HClPurity:99.77%Color and Shape:White Solid CrystallineMolecular weight:215.63MAT2A inhibitor 2
CAS:<p>MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).</p>Formula:C18H24ClN3O3Purity:99.52%Color and Shape:SolidMolecular weight:365.85Bufexamac
CAS:<p>Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.</p>Formula:C12H17NO3Purity:99.73%Color and Shape:Acicular CrystalMolecular weight:223.27Diflunisal
CAS:<p>Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.</p>Formula:C13H8F2O3Purity:98.92% - 99.42%Color and Shape:SolidMolecular weight:250.20Nicotinamide riboside
CAS:<p>Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-</p>Formula:C11H15N2O5Purity:98.82% - 99.58%Color and Shape:SolidMolecular weight:255.25WDR5-IN-6
CAS:<p>WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6</p>Formula:C13H8Cl2N2O2SPurity:99.69%Color and Shape:SoildMolecular weight:327.19NU6140
CAS:<p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52Tulmimetostat
CAS:<p>Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced</p>Formula:C28H36ClN3O5SPurity:98.04% - 99.872%Color and Shape:SolidMolecular weight:562.12VTP50469
CAS:<p>VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.</p>Formula:C32H47FN6O4SPurity:98.31% - 99.55%Color and Shape:SolidMolecular weight:630.82GNE-781
CAS:<p>GNE-781: potent CBP inhibitor (IC50: 0.94 nM), also targets BRET/BRD4(1) (IC50: 6.2/5100 nM).</p>Formula:C27H33F2N7O2Purity:99.64% - 99.92%Color and Shape:SolidMolecular weight:525.59SNDX-5613
CAS:<p>Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.</p>Formula:C32H47FN6O4SPurity:99.12% - 99.74%Color and Shape:SolidMolecular weight:630.82Tranylcypromine (2-PCPA) hydrochloride
CAS:<p>Tranylcypromine (2-PCPA) HCl, a MAO inhibitor, treats major, dysthymic, and atypical depression.</p>Formula:C9H11N·HClPurity:99.48% - 99.86%Color and Shape:SolidMolecular weight:169.66N-Desmethyltamoxifen hydrochloride
CAS:<p>N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.</p>Formula:C25H28ClNOPurity:99.15%Color and Shape:SolidMolecular weight:393.95iso-Azalansta
CAS:<p>(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study of cardiovascular disease.</p>Formula:C22H24ClN3O2SPurity:99.53% - 99.89%Color and Shape:SoildMolecular weight:429.96(R)-CR8
CAS:<p>(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.</p>Formula:C24H29N7OPurity:98.41%Color and Shape:SolidMolecular weight:431.53SMARCA-BD ligand 1 for Protac
CAS:<p>SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2</p>Formula:C14H17N5OPurity:99.93%Color and Shape:SolidMolecular weight:271.32L-2-Hydroxyglutaric acid disodium
CAS:<p>L-2-Hydroxyglutaric acid disodium may affect epigenetics and contribute to renal cancer, inhibiting Mi-CK (Km 2.52 mM, Ki 11.13 mM).</p>Formula:C5H6Na2O5Purity:99.92%Color and Shape:SolidMolecular weight:192.08DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Formula:C25H25N3OPurity:98.95%Color and Shape:SolidMolecular weight:383.49ZEN-3694
CAS:<p>ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can</p>Formula:C19H19N5OPurity:98.88% - 99.48%Color and Shape:SolidMolecular weight:333.39BMS-986158
CAS:<p>BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.</p>Formula:C30H33N5O2Purity:98.78%Color and Shape:SolidMolecular weight:495.62LIN28 inhibitor LI71
CAS:<p>LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.</p>Formula:C21H21NO3Purity:95.88%Color and Shape:SolidMolecular weight:335.4ODM-207
CAS:<p>ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.</p>Formula:C22H21N3O3Purity:99.75%Color and Shape:SolidMolecular weight:375.42EHP-101
CAS:<p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>Formula:C28H35NO3Purity:98.36%Color and Shape:SolidMolecular weight:433.58TAK-901
CAS:<p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>Formula:C28H32N4O3SPurity:99.02% - 99.59%Color and Shape:SolidMolecular weight:504.64MAK683
CAS:<p>MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).</p>Formula:C20H17FN6OPurity:98.25% - 99.92%Color and Shape:SolidMolecular weight:376.39Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Formula:C8H14N2O2Purity:99.67% - 99.86%Color and Shape:White Crystalline PowderMolecular weight:170.21Oltipraz
CAS:<p>Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.</p>Formula:C8H6N2S3Purity:98.79% - 99.77%Color and Shape:SolidMolecular weight:226.34Golidocitinib
CAS:<p>Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).</p>Formula:C25H31N9O2Purity:98.87% - 99.88%Color and Shape:SolidMolecular weight:489.57MS402
CAS:<p>MS402 is a novel BD1-selective BET BrD inhibitor.</p>Formula:C20H19ClN2O3Purity:99.72%Color and Shape:SolidMolecular weight:370.83Minocycline hydrochloride
CAS:<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Formula:C23H28ClN3O7Purity:99.28% - >99.99%Color and Shape:Bright Yellow-Orange Amorphous Solid Crystalline YellowMolecular weight:493.94A-395
CAS:<p>A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.</p>Formula:C26H35FN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:486.65Pulrodemstat benzenesulfonate
CAS:<p>Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally inhibitor of lysine specific demethylase-1 (LSD1) with anticancer effect.</p>Formula:C30H29F2N5O5SPurity:97.67%Color and Shape:SolidMolecular weight:609.64PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Purity:95.42%Color and Shape:SoildIlginatinib hydrochloride
CAS:<p>Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.</p>Formula:C21H21ClFN7Purity:99.55%Color and Shape:SolidMolecular weight:425.89Fenbendazole
CAS:<p>Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.</p>Formula:C15H13N3O2SPurity:99.74%Color and Shape:White To Yellowish PowderMolecular weight:299.35FIDAS-5
CAS:<p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>Formula:C15H13ClFNPurity:97.66% - 98.3%Color and Shape:SolidMolecular weight:261.72TRIM24/BRPF1-IN-2
CAS:<p>TRIM24/BRPF1-IN-2 is a TRIM24/BRPF1 dual inhibitor with anticancer activity that inhibits the proliferation of prostate cancer cells.</p>Formula:C20H22N2O4SPurity:98.69% - 99.13%Color and Shape:SoildMolecular weight:386.47PT2399
CAS:<p>PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.</p>Formula:C17H10F5NO4SPurity:98.8% - 99.45%Color and Shape:SolidMolecular weight:419.32Lin28-let-7a antagonist 1
CAS:<p>Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.</p>Formula:C31H29N5O7Purity:99.44%Color and Shape:SolidMolecular weight:583.59JAK2 Inhibitor V
CAS:<p>JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.</p>Formula:C23H24N2OPurity:98.36% - 99.15%Color and Shape:SolidMolecular weight:344.45Chitosan oligosaccharide
CAS:<p>Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine.</p>Formula:C12H24N2O9Purity:98%Color and Shape:SolidMolecular weight:340.327Amifostine
CAS:<p>Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.</p>Formula:C5H15N2O3PSPurity:99.88%Color and Shape:White SolidMolecular weight:214.22Uzansertib phosphate
CAS:<p>Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.</p>Formula:C26H29F3N5O7PPurity:99.75% - 99.79%Color and Shape:SolidMolecular weight:611.51N6-Cyclohexyladenosine
CAS:<p>N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm.</p>Formula:C16H23N5O4Purity:99.84% - 99.98%Color and Shape:SolidMolecular weight:349.38
