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Chromatin/Epigenetics
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
GSK-3484862
CAS:2170136-65-7
GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.
Formula:
C19H19N5OS
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
365.45
Estimated delivery in United States, on Monday 7 Feb 2022
CM-579
CAS:1846570-40-8
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a …
Formula:
C29H40N4O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
492.65
Estimated delivery in United States, on Monday 7 Feb 2022
(+)-JQ-1
CAS:1268524-70-4
(+)-JQ1 is a BET bromodomain inhibitor (IC50: 77 nM/33 nM for BRD4 (1/2)).
Formula:
C23H25ClN4O2S
Purity:
99.97%
Color and Shape:
solid
Molecular weight:
456.99
Estimated delivery in United States, on Monday 7 Feb 2022
Dbet57
CAS:1883863-52-2
dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of …
Formula:
C34H31ClN8O5S
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
699.18
Estimated delivery in United States, on Monday 7 Feb 2022
AES-135
CAS:2361659-61-0
AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 …
Formula:
C33H29F6N3O5S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
693.66
Estimated delivery in United States, on Monday 7 Feb 2022
ZM223
CAS:2031177-48-5
ZM223 is a potent non-covalent inhibitor of NEDD8 activating enzyme (NAE).
Formula:
C23H17F3N4O2S2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
502.53
Estimated delivery in United States, on Monday 7 Feb 2022
Peficitinib
CAS:944118-01-8
Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
Formula:
C18H22N4O2
Purity:
98.0%
Molecular weight:
326.39
Estimated delivery in United States, on Monday 7 Feb 2022
PF-06700841 (P-Tosylate)
CAS:2140301-96-6
PF-06700841 P-Tosylate is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s …
Formula:
C25H29F2N7O4S
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
561.60
Estimated delivery in United States, on Monday 7 Feb 2022
SMYD2-IN-1
CAS:2023788-96-5
SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).
Formula:
C25H25Cl2F2N7O2
Color and Shape:
Solid
Molecular weight:
564.41
Estimated delivery in United States, on Monday 7 Feb 2022
Histone Deacetylase Inhibitor III
CAS:251456-60-7
M344 is a potent HDAC inhibitor with IC50 of 100 nM and able to induce …
Formula:
C16H25N3O3
Purity:
99.95%
Color and Shape:
solid
Molecular weight:
307.39
Estimated delivery in United States, on Monday 7 Feb 2022
MS049 2HCl (1502816-23-0(free base))
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 …
Formula:
C15H26Cl2N2O
Color and Shape:
solid
Molecular weight:
321.28
Estimated delivery in United States, on Monday 7 Feb 2022
I-CBP112
CAS:1640282-31-0
I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.
Formula:
C27H36N2O5
Purity:
99.10%
Color and Shape:
Solid
Molecular weight:
468.59
Estimated delivery in United States, on Monday 7 Feb 2022
GDC-0339
CAS:1428569-85-0
GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable …
Formula:
C20H22F3N7OS
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
465.5
Estimated delivery in United States, on Monday 7 Feb 2022
EML741
CAS:2328074-38-8
EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b. EML741 …
Formula:
C31H49N5O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
523.75
Estimated delivery in United States, on Monday 7 Feb 2022
YHO-13351
CAS:1346753-00-1
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific BCRP inhibitor.
Formula:
C27H37N3O7S2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
579.73
Estimated delivery in United States, on Monday 7 Feb 2022
MS645
CAS:2250091-96-2
MS645 is an inhibitor of bivalent BET bromodomains (BrD) (Ki of 18.4 nM for BRD4-BD1/BD2).
Formula:
C48H54Cl2N10O2S2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
938.04
Estimated delivery in United States, on Monday 7 Feb 2022
Abrocitinib
CAS:1622902-68-4
Abrocitinib (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).
Formula:
C14H20N5O2S
Purity:
99.91%
Color and Shape:
Solid，White To Beige
Molecular weight:
323.41
Estimated delivery in United States, on Monday 7 Feb 2022
GSK467
CAS:1628332-52-4
GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).
Formula:
C17H13N5O2
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
319.32
Estimated delivery in United States, on Monday 7 Feb 2022
BIX-01294
CAS:935693-62-2
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
Formula:
C28H38N6O2
Purity:
99.31%
Color and Shape:
solid
Molecular weight:
490.64
Estimated delivery in United States, on Monday 7 Feb 2022
A-485
CAS:1889279-16-6
A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM …
Formula:
C25H24F4N4O5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
536.48
Estimated delivery in United States, on Monday 7 Feb 2022
MI-463
CAS:1628317-18-9
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
Formula:
C24H23F3N6S
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
484.54
Estimated delivery in United States, on Monday 7 Feb 2022
A966492
CAS:934162-61-5
A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 …
Formula:
C18H17FN4O
Purity:
98.0%
Molecular weight:
324.35
Estimated delivery in United States, on Monday 7 Feb 2022
Centrinone-B
CAS:1798871-31-4
Centrinone-B (LCR-323) is a potent and highly selective inhibitor of PLK4 (Ki: 0.59 nM).
Formula:
C27H27F2N7O5S2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
631.67
Estimated delivery in United States, on Monday 7 Feb 2022
Tenovin-6 Hydrochloride
CAS:1011301-29-3
Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and …
Formula:
C25H35ClN4O2S
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
491.09
Estimated delivery in United States, on Monday 7 Feb 2022
GSK9311 hydrochloride
CAS:2253733-09-2
GSK9311 hydrochloride, a less active analog of GSK6853, can be used as a negative control. …
Formula:
C24H32ClN5O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
474
Estimated delivery in United States, on Monday 7 Feb 2022
PIM1-IN-1
CAS:1417630-95-5
PIM1-IN-1 is a potent and highly selective inhibitor of PIM1/3(IC50s of 7, 5530 and 70 …
Formula:
C25H30N8O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
474.56
Estimated delivery in United States, on Monday 7 Feb 2022
4'-bromo-Resveratrol
CAS:1224713-90-9
4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)
Formula:
C14H11BrO2
Molecular weight:
291.14
Estimated delivery in United States, on Monday 7 Feb 2022
FLLL32
CAS:1226895-15-3
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
Formula:
C28H32O6
Purity:
96.39%
Color and Shape:
solid
Molecular weight:
464.55
Estimated delivery in United States, on Monday 7 Feb 2022
MI-538
CAS:1857417-10-7
MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
Formula:
C27H25F3N8OS
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
566.6
Estimated delivery in United States, on Monday 7 Feb 2022
UNC0379
CAS:1620401-82-2
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
Formula:
C23H35N5O2
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
413.56
Estimated delivery in United States, on Monday 7 Feb 2022
AZD5153 6-Hydroxy-2-naphthoic acid
CAS:1869912-40-2
AZD5153 (6-Hydroxy-2-naphthoic Acid) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in …
Formula:
C25H33N7O3·C11H8O3
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
667.75
Estimated delivery in United States, on Monday 7 Feb 2022
EPZ011989
CAS:1598383-40-4
EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other …
Formula:
C35H51N5O4
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
605.81
Estimated delivery in United States, on Monday 7 Feb 2022
PROTAC BRD9-binding moiety 1
CAS:2097512-23-5
PROTAC BRD9-binding moiety 1 that binds to BRD9, and used for inhibiting BRD9 activity, based …
Formula:
C23H25N3O7S2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
519.59
Estimated delivery in United States, on Monday 7 Feb 2022
TP0463518
CAS:1558021-37-6
TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 …
Formula:
C20H18ClN3O6
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
431.83
Estimated delivery in United States, on Monday 7 Feb 2022
NEO2734
CAS:2081072-29-7
NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 …
Formula:
C22H24F3N3O3
Purity:
98.56%
Color and Shape:
Solid
Molecular weight:
435.44
Estimated delivery in United States, on Monday 7 Feb 2022
Valemetostat tosylate
CAS:1809336-93-3
Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory …
Formula:
C33H42ClN3O7S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
660.22
Estimated delivery in United States, on Monday 7 Feb 2022
MOZ-IN-2
CAS:2055397-88-9
MOZ-IN-2 is an protein MOZ inhibitor(IC50 of 125 μM).
Formula:
C17H13FN4O3S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
372.37
Estimated delivery in United States, on Monday 7 Feb 2022
Kgp-IN-1
CAS:2097865-36-4
Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.
Formula:
C19H24F4N4O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
432.41
Estimated delivery in United States, on Monday 7 Feb 2022
KDM5A-IN-1
CAS:1905481-36-8
KDM5A-IN-1 is a potent and orally bioavailable inhibitor of pan-histone lysine demethylases 5 (IC50s: 45 …
Formula:
C15H22N4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
290.36
Estimated delivery in United States, on Monday 7 Feb 2022
(R)-(-)-JQ1 Enantiomer
CAS:1268524-71-5
(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on …
Formula:
C23H25ClN4O2S
Purity:
98.03%
Color and Shape:
solid
Molecular weight:
456.99
Estimated delivery in United States, on Monday 7 Feb 2022
Hydrocoumarin
CAS:119-84-6
Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin …
Formula:
C9H8O2
Purity:
99.19%
Color and Shape:
Leaflets Physical Description White To Pale Yellow Clear Oily Liquid With A Sweet Odor Solidifies
Molecular weight:
148.16
Estimated delivery in United States, on Monday 7 Feb 2022
CPI-1205
CAS:1621862-70-1
CPI-1205 is a highly potent and selective inhibitor of EZH2(IC50 : 0.002 μM, EC50 : …
Formula:
C27H33F3N4O3
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
518.58
Estimated delivery in United States, on Monday 7 Feb 2022
MI3
CAS:1271738-59-0
MI-3 (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).
Formula:
C18H25N5S2
Molecular weight:
375.55
Estimated delivery in United States, on Monday 7 Feb 2022
PXD-101
CAS:866323-14-0
Belinostat is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in …
Formula:
C15H14N2O4S
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
318.35
Estimated delivery in United States, on Monday 7 Feb 2022
Fedratinib
CAS:936091-26-8
Fedratinib (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent …
Formula:
C27H36N6O3S
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
524.68
Estimated delivery in United States, on Monday 7 Feb 2022
XY1
CAS:1624117-53-8
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of …
Formula:
C17H19N3O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
297.35
Estimated delivery in United States, on Monday 7 Feb 2022
GSK 690 Hydrochloride
GSK 690 is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) (Kd: 9 nM; biochemical …
Formula:
C24H24ClN3O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
405.92
Estimated delivery in United States, on Monday 7 Feb 2022
Alobresib
CAS:1637771-14-2
Alobresib is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.
Formula:
C26H23N5O2
Purity:
98.87%
Color and Shape:
Solid
Molecular weight:
437.5
Estimated delivery in United States, on Monday 7 Feb 2022
INCB057643
CAS:1820889-23-3
INCB057643 is a potent, selective and orally bioavailable BET inhibitor.
Formula:
C20H21N3O5S
Purity:
98.70%
Color and Shape:
Solid
Molecular weight:
415.46
Estimated delivery in United States, on Monday 7 Feb 2022
1,5-Isoquinolinediol
CAS:5154-02-9
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases …
Formula:
C9H7NO2
Purity:
99.43%
Color and Shape:
Of White To White Powder
Molecular weight:
161.16
Estimated delivery in United States, on Monday 7 Feb 2022
Itacitinib
CAS:1334298-90-6
Itacitinib is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.
Formula:
C26H23F4N9O
Purity:
97.57%
Color and Shape:
solid
Molecular weight:
553.53
Estimated delivery in United States, on Monday 7 Feb 2022
EPZ020411
CAS:1700663-41-7
EPZ020411 is a specific and effective inhibitor of PRMT6 (IC50=10 nM).
Formula:
C25H38N4O3
Color and Shape:
Solid
Molecular weight:
442.6
Estimated delivery in United States, on Monday 7 Feb 2022
UNC0642
CAS:1481677-78-4
UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).
Formula:
C29H44F2N6O2
Purity:
99.50%
Color and Shape:
solid
Molecular weight:
546.69
Estimated delivery in United States, on Monday 7 Feb 2022
Gambogenic acid
CAS:173932-75-7
Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.
Formula:
C38H46O8
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
630.8
Estimated delivery in United States, on Monday 7 Feb 2022
Decitabine
CAS:2353-33-5
Decitabine is a DNA methyltransferase inhibitor that incorporates into DNA resulting in hypomethylation of DNA …
Formula:
C8H12N4O4
Purity:
99.00%
Color and Shape:
Physical Description Fine White Crystalline Powder Used As A Drug
Molecular weight:
228.21
Estimated delivery in United States, on Monday 7 Feb 2022
GNE-781
CAS:1936422-33-1
GNE-781 is a highly potent and selective inhibitor of CBP (IC50: 0.94 nM in TR-FRET …
Formula:
C27H33F2N7O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
525.59
Estimated delivery in United States, on Monday 7 Feb 2022
BMS-986165
CAS:1609392-27-9
BMS-986165 inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable …
Formula:
C20H19D3N8O3
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
425.46
Estimated delivery in United States, on Monday 7 Feb 2022
BYK204165
CAS:1104546-89-5
BYK204165 is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 …
Formula:
C15H12N2O2
Purity:
99.61%
Color and Shape:
solid
Molecular weight:
252
Estimated delivery in United States, on Monday 7 Feb 2022
4SC202
CAS:910462-43-0
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, …
Formula:
C23H21N5O3S
Purity:
99.57%
Color and Shape:
solid
Molecular weight:
447.51
Estimated delivery in United States, on Monday 7 Feb 2022
SGI1027
CAS:1020149-73-8
SGI-1027 is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027 …
Formula:
C27H23N7O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
461.52
Estimated delivery in United States, on Monday 7 Feb 2022
Rocilinostat
CAS:1316214-52-4
Ricolinostat is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic …
Formula:
C24H27N5O3
Purity:
99.21%
Color and Shape:
solid
Molecular weight:
433.5
Estimated delivery in United States, on Monday 7 Feb 2022
KDM5-inhibitor
KDM5 inhibitor
Formula:
C16H14N4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
278.31
Estimated delivery in United States, on Monday 7 Feb 2022
AS8351
CAS:796-42-9
AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A …
Formula:
C17H13N3O2
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
291.3
Estimated delivery in United States, on Monday 7 Feb 2022
CBP/EP300-IN-1
CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.
Formula:
C23H23FN2O5
Color and Shape:
solid
Molecular weight:
426.44
Estimated delivery in United States, on Monday 7 Feb 2022
PJ34 hydrochloride
CAS:344458-15-7
PJ34 hydrochloride is a potent specific inhibitor of PARPl/2.
Formula:
C17H18ClN3O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
331.8
Estimated delivery in United States, on Monday 7 Feb 2022
Remetinostat
CAS:946150-57-8
Remetinostat is a hydroxamic acid-based inhibitor of histone deacetylase enzymes. It is under development for …
Formula:
C16H21NO6
Purity:
98.67%
Color and Shape:
solid
Molecular weight:
323.34
Estimated delivery in United States, on Monday 7 Feb 2022
PRMT5-IN-1
CAS:2366149-83-7
PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for …
Formula:
C19H19ClN4O5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
418.83
Estimated delivery in United States, on Monday 7 Feb 2022
KF 13218
CAS:127654-03-9
KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with …
Formula:
C20H20N2O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
336.38
Estimated delivery in United States, on Monday 7 Feb 2022
SIRT-IN-1
CAS:1431411-60-7
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).
Formula:
C19H27N5O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
389.52
Estimated delivery in United States, on Monday 7 Feb 2022
IACS-9571
CAS:1800477-30-8
IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for …
Formula:
C32H42N4O8S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
642.76
Estimated delivery in United States, on Monday 7 Feb 2022
VZ185
CAS:2306193-61-1
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, …
Formula:
C53H67FN8O8S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
995.21
Estimated delivery in United States, on Monday 7 Feb 2022
P300/CBP-IN-3
CAS:2299226-01-8
P300/CBP-IN-3 is an inhibitor of p300/CBP histone acetyltransferase.
Formula:
C24H29N7O
Color and Shape:
Solid
Molecular weight:
431.53
Estimated delivery in United States, on Monday 7 Feb 2022
KHK-IN-2
CAS:2135304-43-5
KHK-IN-2 is a selective and potent ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM.
Formula:
C16H19F3N4O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
372.34
Estimated delivery in United States, on Monday 7 Feb 2022
Tazemetostat trihydrochloride
CAS:1403255-00-4
Tazemetostat trihydrochloride is a selective and orally available inhibitor of EZH2 (IC50: 4 nM for …
Formula:
C34H47Cl3N4O4
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
682.12
Estimated delivery in United States, on Monday 7 Feb 2022
CHDI-390576
CAS:1629729-98-1
CHDI-390576 is a CNS penetrant class IIa HDAC inhibitor (IC50s: 54 nM, 60 nM, 31 …
Formula:
C19H13F4N3O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
391.32
Estimated delivery in United States, on Monday 7 Feb 2022
M89
CAS:2363165-42-6
M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL …
Formula:
C37H47N5O4S
Color and Shape:
Solid
Molecular weight:
657.86
Estimated delivery in United States, on Monday 7 Feb 2022
SW155246
CAS:420092-79-1
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 …
Formula:
C16H11ClN2O5S
Molecular weight:
378.79
Estimated delivery in United States, on Monday 7 Feb 2022
SMARCA-BD ligand 1 for Protac dihydrochloride
CAS:2369053-68-7
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used …
Formula:
C14H19Cl2N5O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
344.24
Estimated delivery in United States, on Monday 7 Feb 2022
NSC 3852
CAS:3565-26-2
NSC 3852 is a potent inhibitor of histone deacetylase.
Formula:
C9H6N2O2
Purity:
98.44%
Color and Shape:
Slightly Yellow To Yellow-Green Powder
Molecular weight:
174.16
Estimated delivery in United States, on Monday 7 Feb 2022
PFI-90
CAS:53995-62-3
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action.PFI-90 has the …
Formula:
C11H10N4O
Molecular weight:
214.22
Estimated delivery in United States, on Monday 7 Feb 2022
FL411
CAS:2118944-88-8
FL-411 is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for …
Formula:
C18H19N3O2S
Purity:
96.23%
Color and Shape:
Solid
Molecular weight:
341.43
Estimated delivery in United States, on Monday 7 Feb 2022
(R)-UT-155
CAS:2031161-54-1
(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.
Formula:
C20H15F4N3O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
405.35
Estimated delivery in United States, on Monday 7 Feb 2022
PARP14 inhibitor H10
CAS:2084811-68-5
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
Formula:
C24H27N7O7S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
557.58
Estimated delivery in United States, on Monday 7 Feb 2022
MS417
CAS:916489-36-6
MS417 is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM …
Formula:
C20H19ClN4O2S
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
414.91
Estimated delivery in United States, on Monday 7 Feb 2022
JDTic dihydrochloride
CAS:785835-79-2
JDTic is a potent antagonist of kappa-opioid receptors (KOR), blocking the -agonist U50, 488-induced antinociception.
Formula:
C28H41Cl2N3O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
538.55
Estimated delivery in United States, on Monday 7 Feb 2022
S 2101
CAS:1239262-36-2
S 2101 is an inhibitor of lysine-specific demethylase 1 (LSD1)(IC50 of 0.99 μM, Ki of …
Formula:
C16H16ClF2NO
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
311.75
Estimated delivery in United States, on Monday 7 Feb 2022
Momelotinib Mesylate
CAS:1056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity …
Formula:
C24H26N6O5S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
510.57
Estimated delivery in United States, on Monday 7 Feb 2022
BD750
CAS:892686-59-8
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 …
Formula:
C14H13N3OS
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
271.34
Estimated delivery in United States, on Monday 7 Feb 2022
Decernotinib
CAS:944842-54-0
Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of …
Formula:
C18H19F3N6O
Purity:
99.45%
Color and Shape:
solid
Molecular weight:
392.38
Estimated delivery in United States, on Monday 7 Feb 2022
PRMT5-IN-2
CAS:1989620-04-3
PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.
Formula:
C17H16ClFN4O4
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
394.78
Estimated delivery in United States, on Monday 7 Feb 2022
Quisinostat 2HCl
CAS:875320-31-3
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with …
Formula:
C21H28Cl2N6O2
Purity:
98.50%
Color and Shape:
Solid
Molecular weight:
467.39
Estimated delivery in United States, on Monday 7 Feb 2022
BET bromodomain inhibitor
CAS:1505453-59-7
BET bromodomain inhibitor is a potent BET inhibitor.
Formula:
C24H20ClN5O2
Color and Shape:
solid
Molecular weight:
445.91
Estimated delivery in United States, on Monday 7 Feb 2022
JAK1-IN-7
CAS:2241039-81-4
JAK1-IN-7 is a Janus-associated kinase 1 (JAK1) inhibitor, has an anti-inflammatory effect.
Formula:
C28H31F2N7O4S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
599.65
Estimated delivery in United States, on Monday 7 Feb 2022
ORY-1001(trans)
CAS:1431303-72-8
ORY-1001, a Potent and Selective Covalent KDM1A/LSD1 Inhibitor, for the Treatment of Acute Leukemia.
Formula:
C15H24Cl2N2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
303.27
Estimated delivery in United States, on Monday 7 Feb 2022
Nicotinamide riboside chloride
CAS:23111-00-4
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin …
Formula:
C11H15ClN2O5
Color and Shape:
solid
Molecular weight:
290.7
Estimated delivery in United States, on Monday 7 Feb 2022
SMYD3-IN-1
CAS:2095160-79-3
SMYD3-IN-1 is an irreversible and selective SMYD3 (SET and MYND domain containing 3) inhibitor(IC50 of …
Formula:
C28H31ClN4O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
507.02
Estimated delivery in United States, on Monday 7 Feb 2022
Rucaparib Camsylate
CAS:1859053-21-6
Rucaparib Camsylate is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding …
Formula:
C29H34FN3O5S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
555.66
Estimated delivery in United States, on Monday 7 Feb 2022
GSK-J4 Hydrochloride
CAS:1797983-09-5
GSK-J4 is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester …
Formula:
C24H28ClN5O2
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
453.97
Estimated delivery in United States, on Monday 7 Feb 2022
RGFP 966
CAS:1357389-11-7
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at …
Formula:
C21H19FN4O
Color and Shape:
solid
Molecular weight:
362.4
Estimated delivery in United States, on Monday 7 Feb 2022
LSD1-IN-6
CAS:2035912-43-5
LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-6 …
Formula:
C15H13BrN2O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
349.18
Estimated delivery in United States, on Monday 7 Feb 2022
