DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
TIQ-A
CAS:420849-22-5
TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.
Formula:
C11H7NOS
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
201.24
Ref: TM-T50098
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 164.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 543.00 € | ||
| 200mg | 750.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Genz-644282
CAS:529488-28-6
Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.
Formula:
C22H21N3O5
Purity:
97.49%
Color and Shape:
Solid
Molecular weight:
407.42
Ref: TM-T7187
| 1mg | 48.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 206.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 468.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Tretazicar
CAS:21919-05-1
CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and …
Formula:
C9H8N4O5
Purity:
96.76% - 99.7%
Color and Shape:
Solid
Molecular weight:
252.18
Ref: TM-T6798
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 305.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
JW 55
CAS:664993-53-7
JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition …
Formula:
C25H26N2O5
Purity:
99.31% - 99.62%
Color and Shape:
Solid
Molecular weight:
434.48
Ref: TM-T1807
| 10mg | 41.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 114.00 € | ||
| 100mg | 182.00 € | ||
| 200mg | 270.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
PIK-75 hydrochloride
CAS:372196-77-5
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits …
Formula:
C16H14BrN5O4S·HCl
Purity:
97.82%
Color and Shape:
Solid
Molecular weight:
488.74
Ref: TM-T2287
| 5mg | 42.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 171.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
RHPS4
CAS:390362-78-4
RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
Formula:
C22H17F2N2·CH3O4S
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
458.48
Ref: TM-T6967
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 368.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Selisistat
CAS:49843-98-3
Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).
Formula:
C13H13ClN2O
Purity:
99% - 99.79%
Color and Shape:
Solid
Molecular weight:
248.71
Ref: TM-T6111
| 5mg | 55.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 236.00 € | ||
| 200mg | 353.00 € | ||
| 500mg | 570.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Resminostat hydrochloride
CAS:1187075-34-8
Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and …
Formula:
C16H20ClN3O4S
Purity:
97.63% - 99.68%
Color and Shape:
Solid
Molecular weight:
385.86
Ref: TM-T4370
| 1mg | 47.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 774.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Remetinostat
CAS:946150-57-8
Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for …
Formula:
C16H21NO6
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
323.34
Ref: TM-T16729
| 5mg | 50.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 205.00 € | ||
| 100mg | 328.00 € | ||
| 200mg | 456.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BYK204165
CAS:1104546-89-5
BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant …
Formula:
C15H12N2O2
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
252.27
Ref: TM-T7896
| 1mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 297.00 € | ||
| 100mg | 442.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Rucaparib
CAS:283173-50-2
Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity …
Formula:
C19H18FN3O
Purity:
98.37% - 99.89%
Color and Shape:
Solid
Molecular weight:
323.36
Ref: TM-T4463
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 356.00 € | ||
| 200mg | 528.00 € | ||
| 500mg | 850.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
3-TYP
CAS:120241-79-4
3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.
Formula:
C7H6N4
Purity:
100% - 100.00%
Color and Shape:
Solid
Molecular weight:
146.15
Ref: TM-T4108
| 5mg | 56.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 256.00 € | ||
| 100mg | 460.00 € | ||
| 500mg | 1,040.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Elimusertib
CAS:1876467-74-1
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 …
Formula:
C20H21N7O
Purity:
98.95% - 99.75%
Color and Shape:
Solid
Molecular weight:
375.43
Ref: TM-T7318
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 551.00 € | ||
| 500mg | 1,179.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SKLB-23bb
CAS:1815580-06-3
SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.
Formula:
C21H24N4O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
396.44
Ref: TM-T5830
| 1mg | 53.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 319.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 617.00 € | ||
| 200mg | 839.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Niraparib tosylate
CAS:1038915-73-9
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
Formula:
C19H20N4O·C7H8O3S
Purity:
98.69% - 99.87%
Color and Shape:
Solid
Molecular weight:
492.59
Ref: TM-T6892
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 226.00 € | ||
| 500mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
UF010
CAS:537672-41-6
UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 …
Formula:
C11H15BrN2O
Purity:
98.03% - 98.11%
Color and Shape:
Solid
Molecular weight:
271.15
Ref: TM-T3205
| 10mg | 46.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 167.00 € | ||
| 200mg | 252.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Trioxsalen
CAS:3902-71-4
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy …
Formula:
C14H12O3
Purity:
98.96%
Color and Shape:
Crystalline Powder
Molecular weight:
228.24
Ref: TM-T4558
| 10mg | To inquire | ||
| 25mg | 39.00 € | ||
| 50mg | 40.00 € | ||
| 100mg | 52.00 € | ||
| 200mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
OSI-027
CAS:936890-98-1
OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 …
Formula:
C21H22N6O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
406.44
Ref: TM-T6319
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Niraparib hydrochloride
CAS:1038915-64-8
Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage …
Formula:
C19H21ClN4O
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
356.85
Ref: TM-T3353
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 142.00 € | ||
| 100mg | 212.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Tucidinostat
CAS:1616493-44-7
Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.
Formula:
C22H19FN4O2
Purity:
97.01% - 98.76%
Color and Shape:
Solid
Molecular weight:
390.41
Ref: TM-T4481
| 5mg | 63.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 413.00 € | ||
| 200mg | 581.00 € | ||
| 500mg | 859.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
