DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(18 products)
- DNA Methyltransferase(459 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,420 products)
- Reverse Transcriptase(42 products)
- Sirtuin(86 products)
- Telomerase(34 products)
- Topoisomerase(129 products)
Show 3 more subcategories
Found 913 products of "DNA Damage/DNA Repair"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Indotecan
CAS:Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).Formula:C26H26N2O7Purity:97% - 98%Color and Shape:SolidMolecular weight:478.49Rubitecan
CAS:Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.Formula:C20H15N3O6Purity:97.54%Color and Shape:Yellow Amorphous PowderMolecular weight:393.35Treosulfan
CAS:Treosulfan (NSC 39069) is a bifunctional alkylating agent used in the treatment of advanced ovarian cancer.Cost-effective and quality-assured.Formula:C6H14O8S2Purity:99.26% - 99.75%Color and Shape:SolidMolecular weight:278.3Ref: TM-T17159
5mg37.00€10mg55.00€25mg100.00€50mg173.00€100mg309.00€200mg432.00€1mL*10mM (DMSO)42.00€Niraparib hydrochloride
CAS:Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purity:98.26% - 99.83%Color and Shape:SolidMolecular weight:473.88Ref: TM-T8842
1mg138.00€5mg295.00€10mg505.00€25mg733.00€50mg888.00€100mg1,251.00€1mL*10mM (DMSO)309.00€Gatifloxacin hydrochloride
CAS:Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.Formula:C19H23ClFN3O4Purity:99.85% - 99.89%Color and Shape:SolidMolecular weight:411.86SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formula:C17H12ClN3O4Purity:99.6%Color and Shape:SolidMolecular weight:357.75Belotecan hydrochloride
CAS:Belotecan hydrochloride (CKD-602) is a synthetic water-soluble camptothecin derivative and topoisomerase I inhibitor with potential antitumor activityFormula:C25H28ClN3O4Purity:99.63% - ≥95%Color and Shape:SolidMolecular weight:469.96Ref: TM-T7551
1mg34.00€5mg66.00€10mg90.00€25mg144.00€50mg200.00€100mg280.00€200mg416.00€1mL*10mM (DMSO)69.00€OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurity:99.49% - 99.65%Color and Shape:SolidMolecular weight:237.26Ref: TM-T2040
1mg37.00€2mg49.00€5mg70.00€10mg97.00€25mg167.00€50mg316.00€100mg570.00€1mL*10mM (DMSO)70.00€Deoxythymidine-5'-triphosphate trisodium
CAS:dTTP trisodium salt, a natural deoxynucleotide for DNA synthesis by DNA polymerase and reverse transcriptase.Formula:C10H14N2Na3O14P3Purity:97.47%Color and Shape:SolidMolecular weight:548.11Lonazolac
CAS:Lonazolac is a nonsteroidal anti-inflammatory drug[1].Formula:C17H13ClN2O2Purity:99.40%Color and Shape:SolidMolecular weight:312.75Ref: TM-T50025
5mg57.00€10mg86.00€25mg131.00€50mg188.00€100mg284.00€200mg426.00€1mL*10mM (DMSO)74.00€PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formula:C19H16N4O3Purity:97.79% - 99.3%Color and Shape:SolidMolecular weight:348.36L755507
CAS:L755507 is an effective, selective agonist of β3-AR（IC50=35 nM）.Formula:C30H40N4O6SPurity:99% - 99.75%Color and Shape:SolidMolecular weight:584.73SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formula:C18H12N4OSPurity:98.72% - 99.85%Color and Shape:SolidMolecular weight:332.38Ref: TM-T1724
1mg39.00€2mg50.00€5mg79.00€10mg120.00€25mg258.00€50mg408.00€100mg588.00€1mL*10mM (DMSO)79.00€GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!Formula:C13H9ClN2O3Purity:98% - 99.98%Color and Shape:Off-White SolidMolecular weight:276.68Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Formula:C13H14Cl2O3Purity:99.63% - >99.99%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:289.15PIK-90
CAS:PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .
Formula:C18H17N5O3Purity:98.25% - ≥95%Color and Shape:SolidMolecular weight:351.36
