Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(143 products)
- CXCR(158 products)
- Cell wall(5 products)
- IL Receptor(110 products)
- IκB/IKK(57 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(2 products)
- NF-κB(386 products)
- NOD(25 products)
- NOS(61 products)
- Nrf2(81 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(60 products)
- TLR(74 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3428 products of "Immunology and Inflammation"
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GNF351
CAS:GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Formula:C24H25N7Purity:98.43%Color and Shape:SolidMolecular weight:411.5Ref: TM-T15410
1mg42.00€5mg89.00€1mL*10mM (DMSO)100.00€10mg137.00€25mg268.00€50mg492.00€100mg662.00€200mg895.00€CU-T12-9
CAS:CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).Formula:C17H13F3N4O2Purity:99.84%Color and Shape:SolidMolecular weight:362.31Ref: TM-T15017
1mg50.00€5mg105.00€1mL*10mM (DMSO)117.00€10mg160.00€25mg268.00€50mg409.00€100mg583.00€Benzoic acid, 4-amino-2-hydroxy-, sodium salt (1:1)
CAS:Formula:C7H6NNaO3Purity:%Molecular weight:175.1172DATPT
CAS:DATPT is a 12WLVSKF17 peptide mimetic molecule with anti-inflammatory and antimicrobial activities.DATPT inhibits the production of reactive oxygen species.Formula:C24H39ClN6O3Purity:99.75%Color and Shape:SolidMolecular weight:495.06Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11b,16b)-
CAS:Formula:C28H37FO7Purity:98%Color and Shape:SolidMolecular weight:504.5876Briakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Purity:>95%Color and Shape:LiquidMolecular weight:143.86 kDaMilatuzumab
CAS:Milatuzumab (MEDI-115) is a humanized monoclonal antibody against CD74.
Purity:100% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:146.66 kDaDiprovocim-X
Diprovocim-X, a potent TLR1/2 agonist, has EC50s of 0.14nM (hTLR) and 0.75nM (mTLR), enhances mice's adaptive immunity.Formula:C66H83N7O10Color and Shape:SolidMolecular weight:1134.41PSMα3
CAS:PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.Formula:C128H192N28O30SColor and Shape:SolidMolecular weight:2635.17P2X7-IN-2 TFA
P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.Formula:C24H22F7N3O4Color and Shape:SolidMolecular weight:549.44Dihydromyristicin
CAS:Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.Formula:C11H14O3Color and Shape:SolidMolecular weight:194.23FITC-labeled ODN 2395 sodium
FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization throughColor and Shape:Odour SolidN-Acetyldopamine dimer-2
CAS:Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.Formula:C20H20N2O6Color and Shape:SolidMolecular weight:384.38FSL-1
CAS:TLR2/6 agonist, may bind TLR10. Activates NF-κB, triggers IL-8, IL-1β, CCL20, TNF-α. Boosts IFNγ-induced CXCL10 in melanoma.Formula:C84H140N14O18SPurity:98%Color and Shape:SolidMolecular weight:1666.16Lemnalol
CAS:Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.Formula:C15H24OPurity:98%Color and Shape:SolidMolecular weight:220.35IKZF-IN-1
IKZF-IN-1 (Compound I) is a molecular glue that degrades the karos zinc finger family proteins (IKZF) IKZF 1/2/3/4 and is used as an immune modulator in cancer and viral infection research.Formula:C26H28FN5O4Color and Shape:SolidMolecular weight:493.53JH-FK-08
JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.
Formula:C45H73N3O13Color and Shape:SolidMolecular weight:864.073NLRP3-IN-14
CAS:NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.Formula:C27H28N2O4Color and Shape:SolidMolecular weight:444.52Withangulatin A
CAS:Withangulatin A, a COX-2 inhibitor from Physalis angulata, has anti-tumor and anti-inflammatory effects.Formula:C30H38O8Color and Shape:SolidMolecular weight:526.622-Isopropyl-1H-imidazole
CAS:2-Isopropyl-1H-imidazole is a weak inhibitor of NO synthase and can be used in related research in the field of life sciences.Formula:C6H10N2Purity:99.71%Color and Shape:SolidMolecular weight:110.16Romurtide
CAS:Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.Formula:C43H78N6O13Purity:98%Color and Shape:SolidMolecular weight:887.126BQ0413
CAS:BQ0413 exhibits high affinity for PSMA, with a dissociation constant (KD) of 89 pM. It demonstrates effective uptake and internalization, with an internalization rate of 44% in PC3-pip cells. After being labeled with [99mTc], BQ0413 can serve as an imaging agent for tumors.Formula:C69H96N12O24SColor and Shape:SolidMolecular weight:1509.63PSB-12379 disodium
PSB-12379 disodium is a nucleotide analogue acting as a potent inhibitor of Ecto-5'-Nucleotidase (CD73), demonstrating inhibitory constants (Ki) of 9.03 nM inFormula:C18H21N5Na2O9P2Color and Shape:SolidMolecular weight:559.31MUC5AC motif peptide
MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.Formula:C63H104N16O26Purity:98%Color and Shape:SolidMolecular weight:1501.62Anti-inflammatory agent 38
Compound 23d, an Nrf2/HO-1 inhibitor, with IC50 of 0.38 μM for NO, reduces cellular ROS for anti-inflammatory research.Formula:C36H46N2O13SColor and Shape:SolidMolecular weight:746.82SN50
CAS:SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.Formula:C129H230N36O29SPurity:99.91%Color and Shape:SolidMolecular weight:2781.5Pelgifatamab
CAS:Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.Purity:97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.36 kDaTLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75BMX-010
CAS:BMX-010, also known as AEOL-10113, is Porphyrin-Based SOD Mimic.Formula:C48H44Cl5MnN8Color and Shape:SolidMolecular weight:965.12TLR7/8 agonist 4 TFA
CAS:TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.Formula:C20H25F3N6O2Color and Shape:SolidMolecular weight:438.45Pepinh-MYD
CAS:Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.Formula:C151H248N50O35S2Color and Shape:SolidMolecular weight:3388.03IKKγ NBD Inhibitory Peptide
CAS:A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF
Formula:C170H259N49O42S1Purity:98%Color and Shape:SolidMolecular weight:3693.3FITC-labeled Agatolimod sodium
FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake andColor and Shape:Odour SolidNω-allyl-L-arginine
CAS:Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS), efficiently inactivating nNOS in a time-dependentFormula:C9H18N4O2Color and Shape:SolidMolecular weight:214.26Anti-inflammatory agent 7
Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.Formula:C36H40N4O9Color and Shape:SolidMolecular weight:672.72ROS inducer 6
ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.Formula:C32H26N2O3Color and Shape:SolidMolecular weight:486.56NLRP3-IN-76
NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα). It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD).Color and Shape:Odour SolidD-NAME (hydrochloride)
CAS:D-NAME, a less active NO synthase inhibitor enantiomer, has mild cardiovascular effects in rats; inactive in mouse nociception.Formula:C7H16ClN5O4Color and Shape:SolidMolecular weight:269.69Factor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.3559diABZI-V/C-DBCO
Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.Formula:C78H89N19O13Color and Shape:SolidMolecular weight:1500.66NLRP3-IN-45
NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM). It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.Formula:C27H30FNO6Color and Shape:SolidMolecular weight:483.53MyD88-IN-1
CAS:MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.Formula:C23H24N6O7SPurity:99.99%Color and Shape:SoildMolecular weight:528.54Ref: TM-T77353
1mg52.00€5mg156.00€1mL*10mM (DMSO)170.00€10mg225.00€25mg374.00€50mg464.00€100mg660.00€500mg1,359.00€Efineptakin alfa
CAS:Efineptakin alfa (NT-17), a recombinant IL-7, boosts CD4+ and CD8+ cell growth and is used in glioblastoma studies.Color and Shape:LiquidNHEJ inhibitor-1
NHEJ inhibitor-1 (C2) is a Pt(II) complex that targets DSB repair to combat Cisplatin-resistant NSCLC by hindering Ku70/Rad51 and inducing ROS.Formula:C30H35N7O8PtSColor and Shape:SolidMolecular weight:848.79BRD5075
BRD5075 is an effective activator of GPR65, stimulating the production of cAMP in a GPR65-dependent manner. Additionally, it reduces the gene expression of IL-1, IL-2, TNF, and chemokines. BRD5075 holds potential for researching multiple sclerosis and inflammatory bowel disease (IBD).Color and Shape:Odour SolidNasunin
CAS:Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.Formula:C42H47ClO23Color and Shape:SolidMolecular weight:955.26Suc-Tyr-Val-Ala-Asp-pNA
CAS:Suc-YVAD-pNA, a chromogenic caspase-1 substrate.Formula:C31H38N6O12Color and Shape:SolidMolecular weight:686.675PROTAC STING degrader-3
PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.Color and Shape:Odour SolidSTING agonist-27
CAS:CF509 is a non-nucleotide STING agonist; it activates STING and combats SARS-CoV strains.Formula:C40H50N14O6Color and Shape:SolidMolecular weight:822.92Siegesbeckialide I
Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.Formula:C20H28O6Color and Shape:SolidMolecular weight:364.43Torudokimab
Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.Purity:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.71 kDaM0324
M0324 is a MUC-1 conditional CD40 agonist composed of an anti-MUC-1 IgG and two identical CD40-targeting camelid VHH domains, selectively activate immune cells.Color and Shape:Odour LiquidCD22 ligand-1
CAS:CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.Formula:C33H34N5NaO10Color and Shape:SolidMolecular weight:683.64Croconazole
CAS:Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils.Formula:C18H15ClN2OPurity:99.71%Color and Shape:SolidMolecular weight:310.78Ref: TM-T9878
1mg54.00€1mL*10mM (DMSO)90.00€5mg92.00€10mg137.00€25mg215.00€50mg316.00€100mg470.00€500mg1,054.00€STING ligand-4
STING ligand-4 (Compound 2) is a nitro-free covalent STING inhibitor with an IC50 of less than 0.2 μM. It can be utilized in the synthesis of PROTACSTINGdegrader-4.Formula:C18H18Cl2N6OColor and Shape:SolidMolecular weight:404.09191SARS-CoV-2 Mpro-IN-41
SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.Formula:C27H23ClN4O3SColor and Shape:SolidMolecular weight:518.11794Keap1-Nrf2-IN-9
CAS:Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.Formula:C31H30N2O11S2Color and Shape:SolidMolecular weight:670.714-Chlorochalcone
CAS:4-Chlorochalcone is achalcone inhibit human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.Formula:C15H11ClOPurity:98.08%Color and Shape:SolidMolecular weight:242.7Camstatin
CAS:An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.Formula:C122H203N39O34Purity:98%Color and Shape:SolidMolecular weight:2760.19VEN-02XX
VEN-02XX is an orally active NLRP3 inhibitor capable of penetrating the brain. It effectively suppresses the release of IL-1β and IL-18, with IC50 values of 0.3 and 0.28 μM, respectively. In the 5XFAD/Rubicon KO mouse model, VEN-02XX aids in restoring memory and cognition, inhibits microgliosis, and alleviates neuroinflammation and tau protein pathology. This compound is valuable for Alzheimer's disease (AD) research.Formula:C18H16ClF3N4OColor and Shape:SolidMolecular weight:396.79COX-2/15-LOX-IN-4
COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX.Formula:C23H20FN3OSPurity:98%Color and Shape:SolidMolecular weight:405.49Anti-MRC2/CD280 Antibody
Anti-MRC2/CD280 Antibody is a humanized anti-MRC2/CD280 antibody that can be used in immunoblotting (WB) and immunohistochemistry experiments.Purity:99.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:Odour LiquidMolecular weight:142.91 kDaPU23
CAS:PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).Formula:C21H19N3O3S2Purity:99.52%Color and Shape:SolidMolecular weight:425.52Ref: TM-T9982
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg80.00€25mg155.00€50mg235.00€100mg349.00€200mg495.00€Crocin-4
CAS:Crocin-4, a saffron carotenoid, is an antioxidant that inhibits Aβ deposits in the brain and may aid Alzheimer's research with anti-tumor effects.
Formula:C27H36O9Color and Shape:SolidMolecular weight:504.5767-epi Maresin 1
CAS:7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.Formula:C22H32O4Color and Shape:SolidMolecular weight:360.494RC529-MDP
RC529-MDP is an immunological adjuvant that couples Toll-like receptors (TLR4a) and NOD-like receptors (NOD2a) to enhance the innate immune response through the TLR4 and NOD2 signaling pathways. In mouse models, RC529-MDP induces high levels of the cytokine interleukin-related factor (IL-6), highlighting its immunostimulatory activity. Additionally, when injected into mice models with ovalbumin (OVA), RC529-MDP elevates OVA-specific antibody responses, T cell responses, and the proportion of memory T cells.Formula:C118H215N10O28PColor and Shape:SolidMolecular weight:2252.99(-)-10,11-Dihydroxyfarnesol
CAS:(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.Formula:C15H28O3Color and Shape:SolidMolecular weight:256.38TAB-004
TAB-004 is a human monoclonal antibody targeting MUC1. It specifically identifies the tMUC1 present in all major subtypes of breast cancer without affecting normal breast epithelial cells. Additionally, TAB-004 is applicable for research on triple-negative breast cancer (TNBC).Color and Shape:Odour LiquidMethyl 3,4-Dihydroxyphenylacetate
CAS:Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor, suppressing EV71 replication in rhabdomyosarcoma (RD) cells, antiviral.Formula:C9H10O4Purity:97.03%Color and Shape:SolidMolecular weight:182.17TMX-201
CAS:TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.Formula:C57H93N6O12PColor and Shape:SolidMolecular weight:1085.36HPK1-IN-57
HPK1-IN-57 (Compound 10c) is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of 0.09 nM. It suppresses the activity of HPK1 kinase, inhibits the phosphorylation of downstream adaptor protein SLP76 (IC50 of 33.74 nM), and effectively induces the secretion of the T cell activation marker IL-2 (EC50 of 84.24 nM). HPK1-IN-57 holds promise for research in tumor immunotherapy.Formula:C30H36F2N8O3Color and Shape:SolidMolecular weight:594.655STING modulator-5
CAS:STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.Formula:C43H45F4N11O5Color and Shape:SolidMolecular weight:871.88Nosantine racemate
CAS:Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).Formula:C14H22N4O2Purity:98%Color and Shape:SolidMolecular weight:278.35Ibuprofen impurity 1
CAS:Ibuprofen impurity 1: anti-inflammatory, inhibits COX-1/COX-2 with IC50s of 13 μM/370 μM.
Formula:C12H16O2Color and Shape:SolidMolecular weight:192.258ROS-ERS inducer 1
Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.Formula:C24H23F2I2N3PtColor and Shape:SolidMolecular weight:840.35(±)-Phrymarolin II
CAS:(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.Formula:C23H22O10Color and Shape:SolidMolecular weight:458.419C3a (70-77)
CAS:C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.Formula:C35H61N13O10Purity:98%Color and Shape:SolidMolecular weight:823.94MLT-231
MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.Color and Shape:SolidGuselkumab
CAS:Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.Purity:SDS-PAGE:95% SEC-HPLC:98.97%Color and Shape:LiquidMolecular weight:144.8 kDaGlu-urea-Lys
CAS:Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.Formula:C12H21N3O7Purity:99.40%Color and Shape:SolidMolecular weight:319.31EG01377 2HCl
CAS:EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377Formula:C26H32Cl2N6O6S2Purity:98.91%Color and Shape:SoildMolecular weight:659.6Ref: TM-T11154L
1mg114.00€5mg281.00€1mL*10mM (DMSO)409.00€10mg432.00€25mg708.00€50mg888.00€100mg1,251.00€200mg1,684.00€PROTAC cGAS degrader-1
PROTAC cGAS degrader-1 (Compound TH35) is a potent and selective cGAS PROTAC degrader, exhibiting DC50 values of 0.9 μM in THP-1 cells and 4.6 μM in RAW 264.7 cells. It effectively inhibits the activation of cGAS signaling induced by dsDNA. PROTAC cGAS degrader-1 also demonstrates anti-inflammatory properties, making it suitable for research into cGAS-related inflammatory diseases. (Pink: cGAS inhibitor; Black: Linker; Blue: E3 ligase ligand)Formula:C36H33Cl2N7O5Color and Shape:SolidMolecular weight:714.6STING agonist-31
CAS:STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,Formula:C43H51N15O6Color and Shape:SolidMolecular weight:873.96c-di-AMP disodium
CAS:c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.Formula:C20H22N10Na2O12P2Color and Shape:SolidMolecular weight:702.38PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purity:98%Color and Shape:SolidMolecular weight:896.09Firefly luciferase-IN-1
CAS:(E)-6-(4-methylbenzylidene) tetrahydronaphthone is a firefly luciferase inhibitor.Formula:C19H16O3Purity:99.90%Color and Shape:SolidMolecular weight:292.33Ref: TM-T9943
1mg109.00€1mL*10mM (DMSO)225.00€5mg235.00€10mg349.00€25mg532.00€50mg745.00€100mg999.00€200mg1,333.00€TLR7 agonist 17
CAS:TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Formula:C25H37N7O3Color and Shape:SolidMolecular weight:483.61IL-1β-IN-1
CAS:IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].Formula:C22H34O2Color and Shape:SolidMolecular weight:330.5G3-C12
CAS:G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.Formula:C74H115N23O23S2Purity:98%Color and Shape:SolidMolecular weight:1758.997-O-Methylaloeasinol
CAS:7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.Formula:C20H26O9Color and Shape:SolidMolecular weight:410.4196-Amyl-2-pyrone
CAS:6-Amyl-2-pyrone exhibits inhibitory activity against tyrosinase, antibacterial and antiviral activity against Penicillium vulpinum and Aspergillus flavus, and antifungal activity against Sclerotinia sp.Formula:C10H14O2Purity:99.00%Color and Shape:SolidMolecular weight:166.22SjDX5-271
CAS:SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.Formula:C137H215N47O49SColor and Shape:SolidMolecular weight:3336.52Eritoran
CAS:Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.Formula:C66H126N2O19P2Color and Shape:SolidMolecular weight:1313.66EB-TCIP
EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.Color and Shape:Odour SolidSTING agonist-8 dihydrochloride
STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.Formula:C41H48Cl2N14O4Color and Shape:SolidMolecular weight:871.82CBT-295
CBT-295, an orally active autotaxin (ATX) inhibitor, effectively decreases inflammatory cytokines including TGF-β, TNF-α, and IL-6, along with the bile duct proliferation marker CK-19, and ameliorates liver fibrosis. The compound's ability to reverse liver fibrosis contributes to lowered ammonia levels in the blood and brain, which in turn reduces ammonia-induced neuroinflammation. CBT-295 shows potential for the study of liver cirrhosis and related encephalopathy.Formula:C18H20ClN3OColor and Shape:SolidMolecular weight:329.82NBD peptide
CAS:NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.Formula:C62H88N14O20Color and Shape:SolidMolecular weight:1349.44Nemolizumab
CAS:Nemolizumab (CIM331) is an anti-IL-31 receptor A monoclonal antibody for atopic dermatitis and pruritus study.Purity:100% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:144.92 kDaIsoxaben
CAS:Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose intoFormula:C18H24N2O4Purity:99.36%Color and Shape:SolidMolecular weight:332.39Antiviral agent 38
CAS:(6R)-6-Tert-butyl-10-(3-methoxypropoxy)-dihydro-2-oxo-indazole carboxylic acid has antiviral and antibacterial properties, useful for Hepatitis B research.Formula:C23H27N3O5Purity:99.99%Color and Shape:SoildMolecular weight:425.48
