Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3035 products of "Immunology and Inflammation"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Butan-1-amine hydrochloride
CAS:<p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>Formula:C4H12ClNColor and Shape:SolidMolecular weight:109.6Dalutrafusp alfa
CAS:<p>Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].</p>Color and Shape:LiquidMipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Color and Shape:LiquidMurrayafoline A
CAS:<p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>Formula:C14H13NOColor and Shape:SolidMolecular weight:211.264GSK2831781
<p>GSK2831781 is a human IgG1 monoclonal antibody (mAb) designed to target CD223/LAG3. This compound is applicable in research studies focused on ulcerative colitis. For experimental controls, the recommended isotype control is Human IgG1 kappa.</p>Color and Shape:Odour LiquidBMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Color and Shape:Odour LiquidNLRP3-IN-74
<p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>Color and Shape:Odour SolidNLRP3-IN-48
<p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>Color and Shape:Odour SolidRIPK1-IN-25
<p>RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.</p>Color and Shape:Odour SolidEfmarodocokin alfa
CAS:<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Color and Shape:LiquidBI1543673
<p>BI1543673 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It can diminish inflammatory responses in human lung tissue stimulated by TLR4 and TLR7/8. Additionally, BI1543673 reduces inflammatory signaling in a mouse lung inflammation model induced by LPS.</p>Color and Shape:Odour SolidNLRP3-IN-51
<p>NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.</p>Color and Shape:Odour SolidSTING-IN-6
CAS:<p>STING-IN-6 (compound 50), a potent inhibitor of STING, exhibits a pIC50 value of 8.9, indicating its significant inhibitory capacity.</p>Formula:C46H52N12O6Color and Shape:SolidMolecular weight:868.98Bectumomab
CAS:<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Color and Shape:LiquidIFN-α Receptor Recognition Peptide 1
CAS:<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formula:C35H59N13O12SPurity:98%Color and Shape:SolidMolecular weight:885.99STING agonist-29
CAS:<p>CF511: non-nucleotide, small-molecule STING activator; fights SARS-CoV variants.</p>Formula:C38H44N14O6Color and Shape:SolidMolecular weight:792.85Anticancer agent 15
CAS:<p>Anticancer agent 15 raises ROS, causing necroptosis in melanoma cells.</p>Formula:C35H40Cl2N2O5Color and Shape:SolidMolecular weight:639.61PNT2001
CAS:<p>PNT2001 (LY4181530) is an effective prostate-specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. It enhances cellular internalization and, when labeled with 177Lu and 225Ac, is applicable for prostate cancer research.</p>Formula:C85H107N15O32Color and Shape:SolidMolecular weight:1850.84Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Formula:C21H22F2N8O10P2S2Color and Shape:SolidMolecular weight:710.52Sacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Color and Shape:LiquidMolecular weight:150 kDaDamnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Color and Shape:SolidMolecular weight:284.267Englumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Color and Shape:Odour LiquidMifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Formula:C61H110F3N6O21PColor and Shape:SolidMolecular weight:1351.52Vemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.493Dihydromyristicin
CAS:<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Formula:C11H14O3Color and Shape:SolidMolecular weight:194.23Ubletamig
CAS:<p>Ubletamig is a humanized IgG4κ monoclonal antibody that targets MUC16.</p>Color and Shape:LiquidTri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Formula:C78H125N7O42Color and Shape:SolidMolecular weight:1832.85BTH1704
<p>BTH1704 is a human monoclonal antibody targeting MUC1. It facilitates the killing of iC3b-opsonized tumor cells by leukocytes triggered by PGG. BTH1704 is applicable in studies on pancreatic cancer and breast cancer.</p>Color and Shape:Odour LiquidPterisolic acid B
<p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>Formula:C20H26O4Color and Shape:SolidMolecular weight:330.424Pegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Color and Shape:LiquidNLRP3-IN-46
<p>NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.</p>Color and Shape:Odour SolidCD73-IN-16
<p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>Color and Shape:Odour SolidTBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formula:C31H36F2N8O4Color and Shape:SolidMolecular weight:622.678SU1261
<p>SU1261, an IKK inhibitor, exhibits Ki values of 10 nM for IKKα and 680 nM for IKKβ. It effectively inhibits non-canonical NF-κB signaling in U2OS osteosarcoma cells.</p>Color and Shape:Odour SolidDiprovocim-X
<p>Diprovocim-X, a potent TLR1/2 agonist, has EC50s of 0.14nM (hTLR) and 0.75nM (mTLR), enhances mice's adaptive immunity.</p>Formula:C66H83N7O10Color and Shape:SolidMolecular weight:1134.41P2X7-IN-2 TFA
<p>P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.</p>Formula:C24H22F7N3O4Color and Shape:SolidMolecular weight:549.44N-Acetyldopamine dimer-2
CAS:<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Formula:C20H20N2O6Color and Shape:SolidMolecular weight:384.38COX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Color and Shape:Odour SolidSTING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formula:C39H46N14O6Color and Shape:SolidMolecular weight:806.87Avatrombopag hydrochloride
CAS:<p>Avatrombopag (AKR-501) - oral, nonpeptide TPO receptor agonist, EC50 3.3 nM, boosts platelet production, CYP2C9 and CYP3A substrate.</p>Color and Shape:SolidL-156,602
CAS:<p>L-156,602 has a wide range of applications in life science related research.</p>Formula:C38H64N8O13Color and Shape:SolidMolecular weight:840.973Ac-LDEETGEFL-NH2
CAS:<p>Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor</p>Formula:C48H72N10O19Color and Shape:SolidMolecular weight:1093.14Nurulimab
CAS:<p>Nurulimab (BCD-145) is an anti-CTLA-4 antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.</p>Purity:95.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 97.3% (SEC-HPLC)Color and Shape:LiquidExosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Color and Shape:Odour SolidLYT-200
<p>Lyt-200 is a humanized monoclonal antibody targeting galectin-9 (Galectin-9). It effectively inhibits leukemia cells and can also be studied in combination with methotrexate.</p>Color and Shape:Odour LiquidAPF
CAS:<p>APF, a low-fluorescence probe, turns bright (490/515 nm) when oxidized by specific radicals; not affected by NO or H2O2.</p>Formula:C26H17NO5Color and Shape:SolidMolecular weight:423.42Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Color and Shape:Odour LiquidIsuventatug
CAS:<p>Isuventatug is a monoclonal antibody that targets human MICA (MHC I chain-related molecule A) and MICB (MHC I chain-related molecule B). By binding to MICA and MICB, Isuventatug modulates the interaction between immune cells and tumor cells, exhibiting anti-tumor activity. This compound holds potential for research in cancer immunotherapy.</p>Color and Shape:LiquidMyD88-IN-1
CAS:<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formula:C23H24N6O7SPurity:>99.99%Color and Shape:SoildMolecular weight:528.54BR102910
CAS:<p>BR102910: Selective FAP inhibitor, features 4-thiazolecarboxamide with cyano-difluoro-pyrrolidine and dichlorophenyl elements.</p>Formula:C18H14Cl2F2N4O2SPurity:97%Color and Shape:SolidMolecular weight:459.3
