Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3044 products of "Immunology and Inflammation"
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STING-IN-5
CAS:<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Formula:C47H67NO9S2Purity:98%Color and Shape:SolidMolecular weight:854.17Anti-inflammatory agent 46
CAS:<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Formula:C24H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:434.48RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46hnNOS-IN-2
CAS:<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Formula:C18H23F2N3Purity:98%Color and Shape:SolidMolecular weight:319.39IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67ICy-Q
CAS:<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Formula:C48H50I2N2O5Purity:98%Color and Shape:SolidMolecular weight:988.73NLRP3-IN-21
CAS:<p>NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.</p>Formula:C20H13Cl2F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:529.32IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Formula:C37H45N7O4Purity:98%Color and Shape:SolidMolecular weight:651.8IRAK4-IN-28
CAS:<p>IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.</p>Formula:C27H31N9O3Purity:98%Color and Shape:SolidMolecular weight:529.59Galectin-3 antagonist 2
CAS:<p>Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.</p>Formula:C22H23NO10Purity:98%Color and Shape:SolidMolecular weight:461.42RIPK2-IN-3
CAS:<p>RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.</p>Formula:C25H22N4O2Purity:99.57%Color and Shape:SolidMolecular weight:410.47NLRP3-IN-9
CAS:<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Formula:C12H13ClO3Purity:99.64%Color and Shape:SolidMolecular weight:240.68Lobenzarit sodium
CAS:<p>Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.</p>Formula:C14H8ClNNa2O4Purity:99.35%Color and Shape:SolidMolecular weight:335.65Nrf2 activator-7
CAS:<p>Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.</p>Formula:C35H32N2O11S2Color and Shape:SolidMolecular weight:720.77Dexamethasone palmitate
CAS:<p>DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.</p>Formula:C38H59FO6Purity:99.28%Color and Shape:SolidMolecular weight:630.87GW274150 phosphate
CAS:<p>GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.</p>Formula:C8H20N3O6PSPurity:98%Color and Shape:SolidMolecular weight:317.3(-)-Bornyl ferulate
CAS:<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Formula:C20H26O4Purity:98%Color and Shape:SolidMolecular weight:330.42BF738735
CAS:<p>BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).</p>Formula:C21H19FN4O3SPurity:90%Color and Shape:SolidMolecular weight:426.46COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41STING Agonist D61
CAS:<p>STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline</p>Formula:C29H29F3N8O4Color and Shape:SolidMolecular weight:610.60CCG-63802
CAS:<p>CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.</p>Formula:C26H18N4O2SPurity:90%Color and Shape:SolidMolecular weight:450.51ST 2825
CAS:<p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>Formula:C27H28Cl2N4O5SPurity:98%Color and Shape:SolidMolecular weight:591.51EG01377
CAS:<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Formula:C26H30N6O6S2Purity:98%Color and Shape:SolidMolecular weight:586.68Argininosuccinic acid disodium
CAS:<p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>Formula:C10H16N4Na2O6Purity:98%Color and Shape:SolidMolecular weight:334.24TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Formula:C22H23N3SColor and Shape:SolidMolecular weight:361.5STING agonist-11
CAS:<p>STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.</p>Formula:C25H20ClF4N3O2Color and Shape:SolidMolecular weight:505.89BW 755C
CAS:<p>BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.</p>Formula:C10H10F3N3Purity:96.52%Color and Shape:SolidMolecular weight:229.23M-011
CAS:<p>3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.</p>Formula:C18H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:391.49Fendosal
CAS:<p>Fendosal (HP-129), NSAID, 6.9-9.5x stronger than aspirin in chronic inflammation models.</p>Formula:C25H19NO3Purity:99.3%Color and Shape:SolidMolecular weight:381.424-CPPC
CAS:<p>4-CPPC inhibits MIF-2 (IC50=27μM), not MIF-1; blocks MIF-2/CD74 binding and MIF-2-induced ERK1/2 in fibroblasts.</p>Formula:C14H9NO6Purity:97.50% - 98.03%Color and Shape:SolidMolecular weight:287.22TLR9-IN-1
CAS:<p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>Formula:C23H31N7OColor and Shape:SolidMolecular weight:421.54IL-17A antagonist 3
CAS:<p>IL-17A antagonist 3 is an IL-17A antagonist.</p>Formula:C33H33ClN6O4Purity:98%Color and Shape:SolidMolecular weight:613.11MAPK-IN-1
CAS:<p>MAPK-IN-1 inhibits MAPK for Alzheimer's research with anti-inflammatory effects, IC50 of 23.84 μM against AChE.</p>Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Formula:C21H22N4O2SPurity:98%Color and Shape:SolidMolecular weight:394.49(S)-BI 665915
CAS:<p>(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..</p>Formula:C24H26N8O2Purity:98%Color and Shape:SolidMolecular weight:458.52PF 184
CAS:<p>IKKβ inhibitor</p>Formula:C32H32ClFN6O4Purity:98%Color and Shape:SolidMolecular weight:619.09MKA031
CAS:<p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>Formula:C21H17N5O2SColor and Shape:SolidMolecular weight:403.46IRAK4-IN-6
CAS:<p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>Formula:C25H32N10O2Purity:98%Color and Shape:SolidMolecular weight:504.59WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Formula:C22H23N7OPurity:>99.99%Color and Shape:SolidMolecular weight:401.46(Rac)-BAY-985
CAS:<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Formula:C27H30F3N9OPurity:98%Color and Shape:SolidMolecular weight:553.58Cergutuzumab amunaleukin
CAS:<p>Cergutuzumab amunaleukin (CEA-IL2v) is a CEA-targeted IL-2 variant immunocytokine for combination cancer immunotherapy with anti-tumor activity.</p>Purity:98% (SDS-PAGE); 99.7% (SEC-HPLC) - 98% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:162.05 kDaCD73-IN-6
CAS:<p>CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].</p>Formula:C20H15N7O2Color and Shape:SolidMolecular weight:385.38W-54011
CAS:<p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>Formula:C30H37ClN2O2Purity:96.8%Color and Shape:SolidMolecular weight:493.085J-4
CAS:<p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>Formula:C16H12N2O3SPurity:96.12%Color and Shape:SolidMolecular weight:312.34PF-184
<p>PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.</p>Formula:C32H32ClFN6O4Color and Shape:SolidMolecular weight:619.09Glutathione ethyl ester
CAS:<p>Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels.</p>Formula:C12H21N3O6SPurity:98.958%Color and Shape:SoildMolecular weight:335.38Thromboxane B3
CAS:<p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>Formula:C20H32O6Color and Shape:SolidMolecular weight:368.5IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Formula:C21H21N5O4SPurity:98.86%Color and Shape:SolidMolecular weight:439.49AD 0261
CAS:<p>AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.</p>Formula:C27H31F2N3OPurity:98%Color and Shape:SolidMolecular weight:451.55AHR antagonist 4
CAS:<p>AHR antagonist 4, potent with 82.2 nM IC50, inhibits AHR from patent WO2018146010A1 and shows anti-cancer properties.</p>Formula:C20H14F6N4O4Purity:98%Color and Shape:SolidMolecular weight:488.34
