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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3034 products of "Immunology and Inflammation"

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  • Leteprinim
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    Leteprinim

    CAS:
    <p>Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from</p>
    Formula:C15H13N5O4
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:327.29

    Ref: TM-T32658L

  • Nrf2-IN-3
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    Nrf2-IN-3

    CAS:
    <p>Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.</p>
    Formula:C22H26N4O4S
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:442.53

    Ref: TM-T78841

  • LTβR-IN-1
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    LTβR-IN-1

    CAS:
    <p>LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.</p>
    Formula:C18H16N4O2
    Purity:98.93%
    Color and Shape:Solid
    Molecular weight:320.35

    Ref: TM-T11886

  • ERDRP-0519
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    ERDRP-0519

    CAS:
    <p>ERDRP-0519 is an oral measles polymerase inhibitor, preventing disease in monkeys, with potent nanomolar efficacy against morbilliviruses.</p>
    Formula:C23H30F3N5O4S
    Purity:98.64% - 98.71%
    Color and Shape:Solid
    Molecular weight:529.58

    Ref: TM-T24040

  • (±)-CPSI-1306
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    (±)-CPSI-1306

    CAS:
    <p>(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can</p>
    Formula:C15H16F2N2O3
    Purity:97.46%
    Color and Shape:Solid
    Molecular weight:310.3

    Ref: TM-T17315

  • AVP-13358
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    AVP-13358

    CAS:
    <p>AVP-13358: a CD23/IgE inhibitor for treating immune, infection, and ENT disorders.</p>
    Formula:C30H29N5O2
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:491.58

    Ref: TM-T30231

  • CU-CPD107
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    CU-CPD107

    CAS:
    <p>CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.</p>
    Formula:C16H21IN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.25

    Ref: TM-T35349

  • GB1107
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    GB1107

    CAS:
    <p>GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.</p>
    Formula:C20H16Cl2F3N3O4S
    Purity:98.33% - 99.87%
    Color and Shape:Solid
    Molecular weight:522.32

    Ref: TM-T15372

  • RIPK1-IN-4
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    RIPK1-IN-4

    CAS:
    <p>RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s</p>
    Formula:C23H23N5O2
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:401.46

    Ref: TM-T12730

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    Netakimab

    CAS:
    <p>Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.</p>
    Purity:95%
    Color and Shape:Liquid
    Molecular weight:145.74 kDa

    Ref: TM-T77098

  • GW274150
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    GW274150

    CAS:
    <p>GW274150: selective oral iNOS inhibitor (Kd=40 nM), low activity on eNOS/nNOS, protective in acute lung injury.</p>
    Formula:C8H17N3O2S
    Purity:96.43%
    Color and Shape:Solid
    Molecular weight:219.3

    Ref: TM-T11518L

  • IL-17 modulator 4
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    IL-17 modulator 4

    CAS:
    <p>IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.Cost-effective and quality-assured.</p>
    Formula:C27H34N6O2
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:474.6

    Ref: TM-T36526

  • Piflufolastat
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    Piflufolastat

    CAS:
    <p>Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA.</p>
    Formula:C18H23FN4O8
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:442.4

    Ref: TM-T31224

  • Antiviral agent 34
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    Antiviral agent 34

    CAS:
    <p>Antiviral Agent 34 is an antiviral compound that inhibits influenza virus and inhibits the proliferation of influenza virus by modulating RNA polymerase.</p>
    Formula:C29H33N3O2S
    Purity:99.51%
    Color and Shape:Soild
    Molecular weight:487.66

    Ref: TM-T77632

  • Iptacopan
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    Iptacopan

    CAS:
    <p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>
    Formula:C25H30N2O4
    Purity:99.07% - >99.99%
    Color and Shape:Solid
    Molecular weight:422.52

    Ref: TM-T11864

  • Supercinnamaldehyde
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    Supercinnamaldehyde

    CAS:
    <p>Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 of 0.8 μM, and induces activation of TRPA1 ion</p>
    Formula:C12H11NO2
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:201.22

    Ref: TM-T78082

  • Sembragiline
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    Sembragiline

    CAS:
    <p>Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).</p>
    Formula:C19H19FN2O3
    Purity:99.49% - 99.49%
    Color and Shape:Solid
    Molecular weight:342.36

    Ref: TM-T28750

  • ADS032
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    ADS032

    CAS:
    <p>ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.</p>
    Formula:C22H29NO4S
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:403.54

    Ref: TM-T79906

  • Oditrasertib
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    Oditrasertib

    CAS:
    <p>Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.</p>
    Formula:C14H15F2N3O2
    Purity:98.65% - 99.65%
    Color and Shape:Solid
    Molecular weight:295.28

    Ref: TM-T69726

  • Usnoflast
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    Usnoflast

    CAS:
    <p>Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.</p>
    Formula:C21H29N3O3S
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:403.54

    Ref: TM-T79864

  • ABR-238901
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    ABR-238901

    CAS:
    <p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>
    Formula:C11H9BrClN3O4S
    Purity:98.63% - 98.71%
    Color and Shape:Solid
    Molecular weight:394.63

    Ref: TM-T39115

  • Xanthine oxidase-IN-10
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    Xanthine oxidase-IN-10

    CAS:
    <p>Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.</p>
    Formula:C10H8N2OS
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:204.25

    Ref: TM-T78984

  • COX-2/15-LOX-IN-5
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    COX-2/15-LOX-IN-5

    CAS:
    <p>COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-κB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.</p>
    Formula:C25H21N3O3S
    Color and Shape:Solid
    Molecular weight:443.52

    Ref: TM-T86081

  • MG-T-19
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    MG-T-19

    CAS:
    <p>MG-T-19, a TIM-3 inhibitor, inhibit the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs.</p>
    Formula:C18H8Br2ClF3N4O2S
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:596.6

    Ref: TM-T201721

  • CVN293
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    CVN293

    CAS:
    <p>CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia</p>
    Formula:C14H10FN7O
    Purity:99.50%
    Color and Shape:Solid
    Molecular weight:311.27

    Ref: TM-T86109

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    Heme Oxygenase-1-IN-2

    <p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>
    Formula:C19H18ClN3O
    Color and Shape:Solid
    Molecular weight:339.82

    Ref: TM-T61078

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    MMG-11 quarterhydrate

    <p>MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.</p>
    Formula:C15H16O8
    Color and Shape:Solid
    Molecular weight:310.78

    Ref: TM-T60763

  • NLRP3-IN-80
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    NLRP3-IN-80

    CAS:
    <p>NLRP3-IN-80 (Compound 1) is an NLRP3 inhibitor useful for research into inflammatory aging.</p>
    Formula:C24H22F2N4O3
    Color and Shape:Solid
    Molecular weight:452.45

    Ref: TM-T207648

  • Ambuic acid
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    Ambuic acid

    CAS:
    <p>Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.</p>
    Formula:C19H26O6
    Color and Shape:Solid
    Molecular weight:350.41

    Ref: TM-T71860

  • STING agonist-21
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    STING agonist-21

    CAS:
    <p>STING agonist-21 (compound 1), possessing an EC 50 of 592.8 nM, functions as a STING agonist. It is applicable in cancer research [1].</p>
    Formula:C17H11F6N5O2
    Color and Shape:Solid
    Molecular weight:431.29

    Ref: TM-T87445

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    Anti-inflammatory agent 10

    <p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>
    Formula:C17H13BrN4O3S2
    Color and Shape:Solid
    Molecular weight:465.34

    Ref: TM-T62967

  • NLRP3-IN-8
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    NLRP3-IN-8

    CAS:
    <p>NLRP3-IN-8, orally active inflammasome blocker, IC50 of 1.23μM, stable (t1/2 = 138.63min), non-toxic (IC50 &gt;100μM).</p>
    Formula:C23H20N2O6
    Color and Shape:Solid
    Molecular weight:420.41

    Ref: TM-T62221

  • Factor B-IN-4
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    Factor B-IN-4

    CAS:
    <p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C27H32N2O4
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T62688

  • Galectin-3-IN-3
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    Galectin-3-IN-3

    CAS:
    <p>Galectin-3-IN-3 (Compound 4) serves as a selective and orally active inhibitor targeting Gal-3. It exhibits IC50 values of 11 nM for mGal-3 and 84 nM for hGal-3 [1].</p>
    Formula:C25H22ClF2N7O4S
    Color and Shape:Solid
    Molecular weight:590.00

    Ref: TM-T86486

  • (Rel)-Factor B-IN-5
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    (Rel)-Factor B-IN-5

    CAS:
    <p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>
    Formula:C27H32N2O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T62689

  • ALR-6
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    ALR-6

    CAS:
    <p>ALR-6, an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP, possesses anti-inflammatory properties. It significantly inhibits 5-LOX product formation (&gt;80%) in pro-inflammatory M1-MDM without substantially affecting direct inhibition of 5-LOX [1].</p>
    Formula:C18H14O5
    Color and Shape:Solid
    Molecular weight:310.3

    Ref: TM-T85639

  • AhR agonist 7
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    AhR agonist 7

    CAS:
    <p>Compound 8, an AhR agonist 7, demonstrates potent activation of AhR with an EC50 of 13nM [1].</p>
    Formula:C16H15ClFNO2
    Color and Shape:Solid
    Molecular weight:307.75

    Ref: TM-T85606

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    COX-2/PI3K-IN-2

    <p>COX-2/PI3K-IN-2 (5f): anti-inflammatory &amp; anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).</p>
    Formula:C16H17N5O2
    Color and Shape:Solid
    Molecular weight:311.34

    Ref: TM-T60769

  • meso-Zeaxanthin
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    meso-Zeaxanthin

    CAS:
    <p>meso-Zeaxanthin accumulates in the central retina and, together with lutein and zeaxanthin, forms the macular pigment, which functions as a light filter. meso-Zeaxanthin can quench reactive oxygen species (ROS), thereby exhibiting antioxidant properties.</p>
    Formula:C40H56O2
    Color and Shape:Solid
    Molecular weight:568.871

    Ref: TM-T204572

  • Polvitolimod
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    Polvitolimod

    CAS:
    <p>Polvitolimod is a TLR7 agonist used to treat infectious disease and cancer.</p>
    Formula:C13H14FN5O4
    Color and Shape:Solid
    Molecular weight:323.28

    Ref: TM-T60875

  • BMS-986458
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    BMS-986458

    CAS:
    <p>BMS-986458 is a highly selective, orally active BCL6 PROTAC degrader. It specifically targets cereblon (CRBN) and the BCL6 N-terminal BTB domain to catalyze proximity-induced BCL6 degradation. BMS-986458 is applicable for research in B-cell non-Hodgkin lymphoma.</p>
    Formula:C32H34ClN9O3
    Color and Shape:Solid
    Molecular weight:628.124

    Ref: TM-T206353

  • ODN 2088
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    ODN 2088

    CAS:
    <p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>
    Color and Shape:Solid

    Ref: TM-T64278

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    TLR7/8 antagonist 2

    <p>TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.</p>
    Formula:C22H26FN5
    Color and Shape:Solid
    Molecular weight:379.47

    Ref: TM-T61601

  • YE6144
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    YE6144

    CAS:
    <p>YE6144, IRF5 phosphorylation blocker. Affordable Excellence: Reliable Quality You Can Trust</p>
    Formula:C21H27ClFN7O
    Color and Shape:Solid
    Molecular weight:447.94

    Ref: TM-T62678

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    COX-2-IN-12

    <p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>
    Formula:C17H19NO3
    Color and Shape:Solid
    Molecular weight:285.34

    Ref: TM-T60566

  • Ac5GalNTGc
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    Ac5GalNTGc

    CAS:
    <p>Ac5GalNTGc, an analog of hexosamine, inhibits mucin-type O-linked glycosylation biosynthesis [1].</p>
    Formula:C18H25NO11S
    Color and Shape:Solid
    Molecular weight:463.46

    Ref: TM-T85546

  • Corannulene
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    Corannulene

    CAS:
    <p>Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.</p>
    Formula:C20H10
    Color and Shape:Solid
    Molecular weight:250.293

    Ref: TM-T204413

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    IRAK4-IN-11

    <p>IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].</p>
    Formula:C16H19N7O
    Color and Shape:Solid
    Molecular weight:325.37

    Ref: TM-T60899

  • MAY0132
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    MAY0132

    CAS:
    <p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>
    Formula:C16H15ClF3N
    Color and Shape:Solid
    Molecular weight:313.745

    Ref: TM-T204630

  • 2-Guanidinobezimidazole
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    2-Guanidinobezimidazole

    CAS:
    <p>2-Guanidinobenzimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 μM for His-GFP-NLRP3. It directly binds to the LRR domain of NLRP3, facilitating the assembly and activation of the inflammasome. Additionally, 2-Guanidinobenzimidazole enhances antitumor immunity, inhibits tumor growth, and overcomes resistance to immune checkpoint blockade (ICB).</p>
    Formula:C8H9N5
    Color and Shape:Solid
    Molecular weight:175.191

    Ref: TM-T206771