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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

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  • Berbamine

    CAS:
    <p>Berbamine is a natural product extracted from Phellodendron amurense.</p>
    Formula:C37H40N2O6
    Purity:98.92% - 99.67%
    Color and Shape:White Crystal Powder
    Molecular weight:608.72
  • Dauricine

    CAS:
    <p>1.</p>
    Formula:C38H44N2O6
    Purity:99.24% - 99.75%
    Color and Shape:White Powder
    Molecular weight:624.77
  • Dendrophenol

    CAS:
    <p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>
    Formula:C17H20O5
    Purity:98.2% - 99.36%
    Color and Shape:Solid
    Molecular weight:304.34
  • SC-514

    CAS:
    <p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>
    Formula:C9H8N2OS2
    Purity:99.88% - >99.99%
    Color and Shape:Solid
    Molecular weight:224.3
  • yangonin

    CAS:
    <p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>
    Formula:C15H14O4
    Purity:98.82% - 99.55%
    Color and Shape:Pale Yellow Powder
    Molecular weight:258.27
  • Iron sucrose

    CAS:
    <p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>
    Formula:C18H24Fe2O24
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:736.1
  • Neochlorogenic acid

    CAS:
    <p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>
    Formula:C16H18O9
    Purity:99.12% - 99.54%
    Color and Shape:White Powder
    Molecular weight:354.31
  • Triacetylresveratrol

    CAS:
    <p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>
    Formula:C20H18O6
    Purity:99.81%
    Color and Shape:Off White Powder
    Molecular weight:354.35
  • Micheliolide

    CAS:
    <p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>
    Formula:C15H20O3
    Purity:98% - 99.37%
    Color and Shape:Solid
    Molecular weight:248.32
  • Licochalcone D

    CAS:
    <p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>
    Formula:C21H22O5
    Purity:99.03% - 99.9%
    Color and Shape:Solid
    Molecular weight:354.4
  • Nitidine chloride

    CAS:
    <p>1.</p>
    Formula:C21H18ClNO4
    Purity:96.59% - 98.91%
    Color and Shape:Solid
    Molecular weight:383.82
  • Rhoifolin

    CAS:
    <p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>
    Formula:C27H30O14
    Purity:98.11% - 98.58%
    Color and Shape:Solid
    Molecular weight:578.52
  • Ginsenoside Rb1

    CAS:
    <p>Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C54H92O23
    Purity:99.12% - 99.76%
    Color and Shape:Solid
    Molecular weight:1109.29
  • GSK481

    CAS:
    <p>GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.</p>
    Formula:C21H19N3O4
    Purity:98.97%
    Color and Shape:Solid
    Molecular weight:377.39
  • Convallatoxin

    CAS:
    <p>Convallatoxin is a natural product.</p>
    Formula:C29H42O10
    Purity:99.27% - 99.53%
    Color and Shape:Prisms From Methanol + Ether Solid
    Molecular weight:550.64
  • Cornuside

    CAS:
    <p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>
    Formula:C24H30O14
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:542.49
  • Bortezomib

    CAS:
    <p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>
    Formula:C19H25BN4O4
    Purity:97.79% - >99.99%
    Color and Shape:Yellow Solid
    Molecular weight:384.24
  • Benzoyloxypaeoniflorin

    CAS:
    <p>Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.</p>
    Formula:C30H32O13
    Purity:98.52% - 99.96%
    Color and Shape:Solid
    Molecular weight:600.57
  • Pyrrolidinedithiocarbamate ammonium

    CAS:
    <p>Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide</p>
    Formula:C5H12N2S2
    Purity:98% - >99.99%
    Color and Shape:Off-White To Pale Yellow Crystals
    Molecular weight:164.29
  • Sodium Aescinate

    CAS:
    <p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>
    Formula:C54H83NaO23
    Purity:95.17%
    Color and Shape:Solid
    Molecular weight:1123.21
  • Specnuezhenide

    CAS:
    <p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>
    Formula:C31H42O17
    Purity:98% - 99.93%
    Color and Shape:Solid
    Molecular weight:686.66
  • γ-Tocotrienol

    CAS:
    <p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>
    Formula:C28H42O2
    Purity:97.27% - 98.13%
    Color and Shape:Solid
    Molecular weight:410.63
  • Ginsenoside Rk3

    CAS:
    <p>Ginsenosides Rk3 &amp; Rh4 may treat inflammation and ischemic heart disease.</p>
    Formula:C36H60O8
    Purity:99.33% - 99.88%
    Color and Shape:Solid
    Molecular weight:620.86
  • MLN120B

    CAS:
    <p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>
    Formula:C19H15ClN4O2
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:366.8
  • PTP1B-IN-1

    CAS:
    <p>PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)</p>
    Formula:C8H8N2O3S
    Purity:99.27%
    Color and Shape:Solid
    Molecular weight:212.23
  • MD2-TLR4-IN-1

    CAS:
    <p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>
    Formula:C22H14Cl2N4O
    Purity:97.74%
    Color and Shape:Solid
    Molecular weight:421.28
  • Rubiadin-1-methyl ether

    CAS:
    <p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>
    Formula:C16H12O4
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:268.26
  • Rhynchophylline

    CAS:
    <p>Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.</p>
    Formula:C22H28N2O4
    Purity:99.44% - 99.98%
    Color and Shape:Red Brown Or White Fine Powder
    Molecular weight:384.47
  • ETHYL CAFFEATE

    CAS:
    <p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>
    Formula:C11H12O4
    Purity:97.79%
    Color and Shape:Solid
    Molecular weight:208.21
  • GSK583

    CAS:
    <p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>
    Formula:C20H19FN4O2S
    Purity:98.68% - 99.81%
    Color and Shape:Solid
    Molecular weight:398.45
  • Isovitexin

    CAS:
    <p>1.</p>
    Formula:C21H20O10
    Purity:99.79% - 99.97%
    Color and Shape:Solid
    Molecular weight:432.38
  • Denosumab

    CAS:
    <p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>
    Formula:C6404H9912N1724O2004S50
    Purity:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%
    Color and Shape:Liquid
    Molecular weight:144.71 kDa
  • JTP 0819958 - HOIPIN-1


    <p>JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.</p>
    Formula:C17H13NaO4
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:304.27
  • Diethylmaleate

    CAS:
    <p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>
    Formula:C8H12O4
    Purity:98%
    Color and Shape:Colourless Liquid
    Molecular weight:172.18
  • Chelidonic acid

    CAS:
    <p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>
    Formula:C7H4O6
    Purity:99.03%
    Color and Shape:Solid
    Molecular weight:184.1
  • Ac2-26 acetate


    <p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>
    Formula:C141H210N32O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3089.43
  • Sinomenine

    CAS:
    <p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>
    Formula:C19H23NO4
    Purity:99.02% - 99.73%
    Color and Shape:White Powder
    Molecular weight:329.39
  • ISOGINKGETIN

    CAS:
    <p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>
    Formula:C32H22O10
    Purity:98% - 99.72%
    Color and Shape:Solid
    Molecular weight:566.51
  • AZD3264

    CAS:
    <p>AZD3264 is a new type IKK2 inhibitor.</p>
    Formula:C21H23N5O4S
    Purity:98.98% - 99.17%
    Color and Shape:Solid
    Molecular weight:441.5
  • Astaxanthin

    CAS:
    <p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>
    Formula:C40H52O4
    Purity:95.1% - 99.79%
    Color and Shape:Needles From Acetone/Light Petroleum Solid
    Molecular weight:596.84
  • Rocaglamide

    CAS:
    <p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>
    Formula:C29H31NO7
    Purity:95.32% - 99.67%
    Color and Shape:Solid
    Molecular weight:505.56
  • Curculigoside

    CAS:
    <p>1.</p>
    Formula:C22H26O11
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:466.44
  • Ethacrynic acid

    CAS:
    <p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。</p>
    Formula:C13H12Cl2O4
    Purity:98.61% - 99.85%
    Color and Shape:Crystals Physical Description White Solid (Ntp 1992)
    Molecular weight:303.14
  • Quinoclamine

    CAS:
    <p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>
    Formula:C10H6ClNO2
    Purity:99.13% - 99.28%
    Color and Shape:Orange Powder
    Molecular weight:207.61
  • 7,4'-Dihydroxyflavone

    CAS:
    <p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>
    Formula:C15H10O4
    Purity:99.39% - 99.6%
    Color and Shape:Solid
    Molecular weight:254.24
  • Rucaparib

    CAS:
    <p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>
    Formula:C19H18FN3O
    Purity:98.24% - 99.80%
    Color and Shape:Solid
    Molecular weight:323.36
  • Geranylgeraniol

    CAS:
    <p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>
    Formula:C20H34O
    Purity:99.17% - ≥98%
    Color and Shape:Solid
    Molecular weight:290.48
  • Adelmidrol

    CAS:
    <p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>
    Formula:C13H26N2O4
    Purity:99.35% - 99.73%
    Color and Shape:Solid
    Molecular weight:274.36
  • GSK2982772

    CAS:
    <p>GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.</p>
    Formula:C20H19N5O3
    Purity:99.27% - 99.31%
    Color and Shape:Solid
    Molecular weight:377.4
  • IRAK inhibitor 1

    CAS:
    <p>IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50&gt;10 μM).</p>
    Formula:C17H19N5
    Purity:97.5% - 99.89%
    Color and Shape:Solid
    Molecular weight:293.37
  • 14-Deoxy-11,12-didehydroandrographolide

    CAS:
    <p>14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.</p>
    Formula:C20H28O4
    Purity:99.13% - 99.93%
    Color and Shape:Solid
    Molecular weight:332.43
  • Rucaparib Phosphate

    CAS:
    <p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>
    Formula:C19H18FN3O·H3PO4
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:421.36
  • Damascenone

    CAS:
    <p>Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.</p>
    Formula:C13H18O
    Purity:98.03%
    Color and Shape:Colorless Liquid
    Molecular weight:190.28
  • IQ-1S free acid

    CAS:
    <p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>
    Formula:C15H9N3O
    Purity:97.92% - 99.05%
    Color and Shape:Solid
    Molecular weight:247.25
  • 20(S)-Ginsenoside Rg3

    CAS:
    <p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>
    Formula:C42H72O13
    Purity:98.11% - 99.93%
    Color and Shape:Solid
    Molecular weight:785.01
  • 2,4-Diamino-6-hydroxypyrimidine

    CAS:
    <p>2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis</p>
    Formula:C4H6N4O
    Purity:99.82%
    Color and Shape:White Solid Crystals
    Molecular weight:126.12
  • Andrographolide

    CAS:
    <p>Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential</p>
    Formula:C20H30O5
    Purity:99.39% - 99.97%
    Color and Shape:Powder
    Molecular weight:350.45
  • 8-Deoxygartanin

    CAS:
    <p>8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has</p>
    Formula:C23H24O5
    Purity:99.04% - 99.88%
    Color and Shape:Solid
    Molecular weight:380.43
  • TAK-243

    CAS:
    <p>TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).</p>
    Formula:C19H20F3N5O5S2
    Purity:98.09% - 98.93%
    Color and Shape:Solid
    Molecular weight:519.52
  • Caffeic Acid Phenethyl Ester

    CAS:
    <p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>
    Formula:C17H16O4
    Purity:99.18% - 99.35%
    Color and Shape:Less Transparent Liquid Colorless Transparent Liquid
    Molecular weight:284.31
  • Betulinic acid

    CAS:
    <p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>
    Formula:C30H48O3
    Purity:99.12% - 99.7%
    Color and Shape:White Crystalline Powder
    Molecular weight:456.7
  • Indacaterol

    CAS:
    <p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>
    Formula:C24H28N2O3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:392.49
  • Rucaparib monocamsylate

    CAS:
    <p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>
    Formula:C29H34FN3O5S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:555.66
  • Tryptanthrin

    CAS:
    <p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>
    Formula:C15H8N2O2
    Purity:99.64% - 99.94%
    Color and Shape:Solid
    Molecular weight:248.24
  • Sauchinone

    CAS:
    <p>Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.</p>
    Formula:C20H20O6
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:356.37
  • GSK547

    CAS:
    <p>GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.</p>
    Formula:C20H18F2N6O
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:396.39
  • Sanggenon C

    CAS:
    <p>Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.</p>
    Formula:C40H36O12
    Purity:97.76% - 99.76%
    Color and Shape:Solid
    Molecular weight:708.71
  • HOMOPLANTAGININ

    CAS:
    <p>Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows</p>
    Formula:C22H22O11
    Purity:97.63% - 99.66%
    Color and Shape:Solid
    Molecular weight:462.4
  • SC75741

    CAS:
    <p>SC75741 is a potent P65 inhibitor with IC50 of 200 nM</p>
    Formula:C29H23N7O2S2
    Purity:99.44% - 99.54%
    Color and Shape:Solid
    Molecular weight:565.67
  • Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Formula:C6H9NOS2
    Purity:97.55% - 99.19%
    Color and Shape:Slightly Yellowish Liquid
    Molecular weight:175.27
  • Ginsenoside Rg5

    CAS:
    <p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>
    Formula:C42H70O12
    Purity:98% - 99.65%
    Color and Shape:Solid
    Molecular weight:767
  • WAY-169916

    CAS:
    <p>WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.</p>
    Formula:C17H13F3N2O2
    Purity:98.63% - 98.64%
    Color and Shape:Solid
    Molecular weight:334.29
  • Astilbin

    CAS:
    <p>Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.</p>
    Formula:C21H22O11
    Purity:97% - 99.86%
    Color and Shape:White Powder
    Molecular weight:450.39
  • Praeruptorin A

    CAS:
    <p>Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin</p>
    Formula:C21H22O7
    Purity:99.63% - 99.65%
    Color and Shape:Solid
    Molecular weight:386.4
  • Tenuigenin

    CAS:
    <p>Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.</p>
    Formula:C30H45ClO6
    Purity:98.9% - 99.53%
    Color and Shape:Solid
    Molecular weight:537.13
  • Tectochrysin

    CAS:
    <p>Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.</p>
    Formula:C16H12O4
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:268.26
  • INH14

    CAS:
    <p>INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).</p>
    Formula:C15H16N2O
    Purity:95.41%
    Color and Shape:Solid
    Molecular weight:240.3
  • Picroside II

    CAS:
    <p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>
    Formula:C23H28O13
    Purity:98% - 99.83%
    Color and Shape:Solid
    Molecular weight:512.46
  • Phorbol 12-myristate 13-acetate

    CAS:
    <p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>
    Formula:C36H56O8
    Purity:98.55% - >99.99%
    Color and Shape:White To Off-White Solid
    Molecular weight:616.83
  • Handelin

    CAS:
    <p>Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.</p>
    Formula:C32H40O8
    Purity:99.02% - 99.345%
    Color and Shape:Solid
    Molecular weight:552.66
  • Sciadopitysin

    CAS:
    <p>Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.</p>
    Formula:C33H24O10
    Purity:98.14% - 99.17%
    Color and Shape:Solid
    Molecular weight:580.54
  • HS-1371

    CAS:
    <p>HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.</p>
    Formula:C24H24N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:384.47
  • Okanin

    CAS:
    <p>Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.</p>
    Formula:C15H12O6
    Purity:95.19% - 99.4%
    Color and Shape:Solid
    Molecular weight:288.25
  • Schisantherin A

    CAS:
    <p>Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.</p>
    Formula:C30H32O9
    Purity:98% - 99.989
    Color and Shape:Solid
    Molecular weight:536.57
  • Necrostatin 2 racemate

    CAS:
    <p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>
    Formula:C13H12ClN3O2
    Purity:98% - 99.5%
    Color and Shape:Solid
    Molecular weight:277.71
  • Esculentoside H

    CAS:
    <p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>
    Formula:C48H76O21
    Purity:98.04% - 99.3%
    Color and Shape:Solid
    Molecular weight:989.1
  • Isoliquiritin apioside

    CAS:
    <p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>
    Formula:C26H30O13
    Purity:98.84% - 99.27%
    Color and Shape:Solid
    Molecular weight:550.51
  • Ginsenoside Re

    CAS:
    <p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purity:99.12% - >99.99%
    Color and Shape:White Powder
    Molecular weight:947.15
  • Suberosin

    CAS:
    <p>Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.</p>
    Formula:C15H16O3
    Purity:97.08% - 99.26%
    Color and Shape:Solid
    Molecular weight:244.29
  • NDMC101

    CAS:
    <p>NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.</p>
    Formula:C13H9ClFNO2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:265.67
  • IRAK4-IN-1

    CAS:
    <p>IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.</p>
    Formula:C19H23N5O
    Purity:98.18% - 99.85%
    Color and Shape:Solid
    Molecular weight:337.42
  • BMS-345541 hydrochloride

    CAS:
    <p>BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).</p>
    Formula:C14H18ClN5
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:291.78
  • IKK 16

    CAS:
    <p>IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.</p>
    Formula:C28H29N5OS
    Purity:98.76% - 99.61%
    Color and Shape:Solid
    Molecular weight:483.63
  • GSK2983559 active metabolite

    CAS:
    <p>GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.</p>
    Formula:C21H22N4O4S2
    Purity:97.07% - 99.57%
    Color and Shape:Solid
    Molecular weight:458.55
  • NF-κΒ activator 2

    CAS:
    <p>NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.</p>
    Formula:C16H11FN2O3
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:298.27
  • Eurycomalactone

    CAS:
    <p>Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.</p>
    Formula:C19H24O6
    Purity:99.48% - 99.87%
    Color and Shape:Solid
    Molecular weight:348.39
  • JSH-23

    CAS:
    <p>JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.</p>
    Formula:C16H20N2
    Purity:98.03% - 99.67%
    Color and Shape:Solid
    Molecular weight:240.34
  • GS143

    CAS:
    <p>GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.</p>
    Formula:C28H19FN2O4
    Purity:97.67%
    Color and Shape:Solid
    Molecular weight:466.46
  • Isodeoxyelephantopin

    CAS:
    <p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>
    Formula:C19H20O6
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:344.36
  • IKKγ NBD Inhibitory Peptide acetate


    <p>IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.</p>
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:N/A