NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 397 products of "NF-κB"
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PTP1B-IN-1
CAS:PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)Formula:C8H8N2O3SPurity:99.27%Color and Shape:SolidMolecular weight:212.23MD2-TLR4-IN-1
CAS:MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.Formula:C22H14Cl2N4OPurity:97.74%Color and Shape:SolidMolecular weight:421.28Ref: TM-T7672
1mg58.00€5mg128.00€10mg200.00€25mg344.00€50mg482.00€100mg637.00€200mg858.00€1mL*10mM (DMSO)141.00€Rubiadin-1-methyl ether
CAS:Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.
Formula:C16H12O4Purity:98.32%Color and Shape:SolidMolecular weight:268.26Rhynchophylline
CAS:Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.Formula:C22H28N2O4Purity:99.44% - 99.98%Color and Shape:Red Brown Or White Fine PowderMolecular weight:384.47ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21GSK583
CAS:GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).Formula:C20H19FN4O2SPurity:98.68% - 99.81%Color and Shape:SolidMolecular weight:398.45Ref: TM-T3537
1mg49.00€2mg69.00€5mg92.00€10mg127.00€25mg216.00€50mg303.00€100mg416.00€200mg605.00€1mL*10mM (DMSO)97.00€Ref: TM-T6S1371
1mg49.00€5mg92.00€10mg133.00€25mg259.00€50mg358.00€100mg530.00€200mg755.00€1mL*10mM (DMSO)100.00€Denosumab
CAS:Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFormula:C6404H9912N1724O2004S50Purity:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Color and Shape:LiquidMolecular weight:144.71 kDaJTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.Formula:C17H13NaO4Purity:99.95%Color and Shape:SolidMolecular weight:304.27Ref: TM-T8951
1mg37.00€2mg50.00€5mg65.00€10mg95.00€25mg210.00€50mg339.00€100mg495.00€500mg1,099.00€1mL*10mM (DMSO)77.00€Diethylmaleate
CAS:Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.Formula:C8H12O4Purity:98%Color and Shape:Colourless LiquidMolecular weight:172.18Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.10Ac2-26 acetate
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).Formula:C141H210N32O44SPurity:98%Color and Shape:SolidMolecular weight:3089.43Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.75%Color and Shape:SolidMolecular weight:566.51AZD3264
CAS:AZD3264 is a new type IKK2 inhibitor.Formula:C21H23N5O4SPurity:98.98% - 99.17%Color and Shape:SolidMolecular weight:441.5Ref: TM-T6771
1mg52.00€2mg70.00€5mg103.00€10mg160.00€25mg311.00€50mg502.00€100mg805.00€500mg1,605.00€1mL*10mM (DMSO)114.00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 99.67%Color and Shape:SolidMolecular weight:505.56Ref: TM-TQ0131
1mg187.00€5mg410.00€10mg710.00€25mg1,381.00€50mg2,352.00€500µg155.00€1mL*10mM (DMSO)449.00€Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。Formula:C13H12Cl2O4Purity:98.61% - 99.85%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Quinoclamine
CAS:Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.Formula:C10H6ClNO2Purity:99.13% - 99.28%Color and Shape:Orange PowderMolecular weight:207.617,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:SolidMolecular weight:254.24Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36Ref: TM-T4463
2mg46.00€5mg70.00€10mg109.00€25mg170.00€50mg222.00€100mg344.00€200mg512.00€500mg823.00€1mL*10mM (DMSO)77.00€Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formula:C20H34OPurity:99.17% - ≥98%Color and Shape:SolidMolecular weight:290.48Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.3614-Deoxy-11,12-didehydroandrographolide
CAS:14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.Formula:C20H28O4Purity:99.13% - 99.93%Color and Shape:SolidMolecular weight:332.43Ref: TM-TQ0185
1mg65.00€5mg152.00€10mg215.00€25mg355.00€50mg530.00€100mg735.00€1mL*10mM (DMSO)138.00€Rucaparib Phosphate
CAS:Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.Formula:C19H18FN3O·H3PO4Purity:99.37%Color and Shape:SolidMolecular weight:421.36Ref: TM-T6127
1mg35.00€2mg50.00€5mg74.00€10mg109.00€25mg178.00€50mg235.00€100mg371.00€200mg553.00€1mL*10mM (DMSO)74.00€Damascenone
CAS:Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.Formula:C13H18OPurity:99.81%Color and Shape:Colorless LiquidMolecular weight:190.2820(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.012,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFormula:C4H6N4OPurity:99.82%Color and Shape:White Solid CrystalsMolecular weight:126.12Andrographolide
CAS:Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potentialFormula:C20H30O5Purity:99.39% - 99.97%Color and Shape:PowderMolecular weight:350.458-Deoxygartanin
CAS:8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFormula:C23H24O5Purity:99.04% - 99.88%Color and Shape:SolidMolecular weight:380.43TAK-243
CAS:TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).Formula:C19H20F3N5O5S2Purity:98.09% - 98.93%Color and Shape:SolidMolecular weight:519.52Ref: TM-T16974
1mg46.00€2mg60.00€5mg90.00€10mg142.00€25mg254.00€50mg434.00€100mg623.00€1mL*10mM (DMSO)102.00€Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Formula:C17H16O4Purity:99.18% - 99.35%Color and Shape:Less Transparent Liquid Colorless Transparent LiquidMolecular weight:284.31Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formula:C30H48O3Purity:98.22% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.70Indacaterol
CAS:Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.Formula:C24H28N2O3Purity:99.96%Color and Shape:SolidMolecular weight:392.49Rucaparib monocamsylate
CAS:Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.
Formula:C29H34FN3O5SPurity:99.82%Color and Shape:SolidMolecular weight:555.66Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Sauchinone
CAS:Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.Formula:C20H20O6Purity:99.12% - >99.99%Color and Shape:SolidMolecular weight:356.37Sanggenon C
CAS:Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.Formula:C40H36O12Purity:97.76% - 99.76%Color and Shape:SolidMolecular weight:708.71Ref: TM-T4S1615
1mg93.00€5mg188.00€10mg283.00€25mg494.00€50mg702.00€100mg938.00€200mg1,301.00€1mL*10mM (DMSO)284.00€HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFormula:C22H22O11Purity:97.63% - 99.66%Color and Shape:SolidMolecular weight:462.40SC75741
CAS:SC75741 is a potent P65 inhibitor with IC50 of 200 nMFormula:C29H23N7O2S2Purity:99.44% - 99.54%Color and Shape:SolidMolecular weight:565.67Ref: TM-T6661
1mg40.00€5mg73.00€10mg105.00€25mg177.00€50mg281.00€100mg432.00€200mg618.00€1mL*10mM (DMSO)93.00€Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purity:97.55% - 99.67%Color and Shape:Slightly Yellowish LiquidMolecular weight:175.27Ref: TM-TL0016
1mg34.00€2mg46.00€5mg66.00€10mg92.00€25mg167.00€50mg241.00€100mg359.00€200mg525.00€1mL*10mM (DMSO)65.00€Ginsenoside Rg5
CAS:Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.Formula:C42H70O12Purity:98% - 99.65%Color and Shape:SolidMolecular weight:767.00Ref: TM-T6S1487
1mg107.00€5mg251.00€10mg404.00€25mg665.00€50mg888.00€100mg1,251.00€1mL*10mM (DMSO)341.00€WAY-169916
CAS:WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.Formula:C17H13F3N2O2Purity:98.63% - 98.64%Color and Shape:SolidMolecular weight:334.29Ref: TM-T8981
2mg39.00€5mg60.00€10mg92.00€25mg187.00€50mg313.00€100mg450.00€200mg620.00€1mL*10mM (DMSO)89.00€Astilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Formula:C21H22O11Purity:97% - 99.86%Color and Shape:White PowderMolecular weight:450.39Ref: TM-T2794
5mg49.00€10mg73.00€25mg133.00€50mg212.00€100mg316.00€200mg452.00€500mg737.00€1mL*10mM (DMSO)49.00€Praeruptorin A
CAS:Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulinFormula:C21H22O7Purity:99.63% - 99.65%Color and Shape:SolidMolecular weight:386.4Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Formula:C30H45ClO6Purity:98.9% - 99.53%Color and Shape:SolidMolecular weight:537.13Ref: TM-T3907
2mg34.00€5mg50.00€10mg73.00€25mg105.00€50mg152.00€100mg215.00€200mg318.00€1mL*10mM (DMSO)63.00€Tectochrysin
CAS:Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.Formula:C16H12O4Purity:99.26%Color and Shape:SolidMolecular weight:268.26INH14
CAS:INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).Formula:C15H16N2OPurity:95.41%Color and Shape:SolidMolecular weight:240.3Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formula:C23H28O13Purity:98% - 99.83%Color and Shape:SolidMolecular weight:512.46Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:616.83Handelin
CAS:Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.Formula:C32H40O8Purity:99.02% - 99.345%Color and Shape:SolidMolecular weight:552.66Sciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Formula:C33H24O10Purity:98.67% - 99.17%Color and Shape:SolidMolecular weight:580.54Ref: TM-T5S2129
1mg49.00€5mg89.00€10mg154.00€25mg288.00€50mg432.00€100mg620.00€500mg1,279.00€1mL*10mM (DMSO)123.00€Okanin
CAS:Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.Formula:C15H12O6Purity:95.19% - 99.4%Color and Shape:SolidMolecular weight:288.25Ref: TM-TN2008
1mg84.00€5mg245.00€10mg295.00€25mg497.00€50mg710.00€100mg964.00€1mL*10mM (DMSO)207.00€Schisantherin A
CAS:Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.Formula:C30H32O9Purity:98% - 99.989Color and Shape:SolidMolecular weight:536.57Esculentoside H
CAS:Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Ginsenoside Re
CAS:Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:99.12% - >99.99%Color and Shape:White PowderMolecular weight:947.15Ref: TM-T2872
2mg35.00€5mg50.00€10mg66.00€25mg97.00€50mg145.00€100mg207.00€200mg306.00€1mL*10mM (DMSO)69.00€Suberosin
CAS:Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.Formula:C15H16O3Purity:97.08% - 99.26%Color and Shape:SolidMolecular weight:244.29Ref: TM-T5795
2mg37.00€5mg54.00€10mg93.00€25mg167.00€50mg241.00€100mg359.00€200mg525.00€1mL*10mM (DMSO)56.00€NDMC101
CAS:NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.Formula:C13H9ClFNO2Purity:99.89%Color and Shape:SolidMolecular weight:265.67BMS-345541 hydrochloride
CAS:BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).Formula:C14H18ClN5Purity:99.13%Color and Shape:SolidMolecular weight:291.78Ref: TM-T8542
1mg38.00€2mg50.00€5mg82.00€10mg119.00€25mg212.00€50mg356.00€100mg533.00€1mL*10mM (DMSO)52.00€NF-κΒ activator 2
CAS:NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.Formula:C16H11FN2O3Purity:98.12%Color and Shape:SolidMolecular weight:298.27Ref: TM-T39924
1mg94.00€2mg136.00€5mg226.00€10mg335.00€25mg538.00€50mg730.00€100mg938.00€1mL*10mM (DMSO)249.00€Eurycomalactone
CAS:Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.Formula:C19H24O6Purity:99.48% - 99.87%Color and Shape:SolidMolecular weight:348.39JSH-23
CAS:JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.Formula:C16H20N2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:240.34Ref: TM-T1930
1mg40.00€2mg54.00€5mg88.00€10mg113.00€25mg177.00€50mg268.00€100mg408.00€1mL*10mM (DMSO)87.00€GS143
CAS:GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.Formula:C28H19FN2O4Purity:97.67%Color and Shape:SolidMolecular weight:466.46Ref: TM-T25465
2mg35.00€5mg55.00€10mg87.00€25mg161.00€50mg245.00€100mg358.00€200mg520.00€1mL*10mM (DMSO)57.00€Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.
Purity:99.15%Color and Shape:SolidMolecular weight:N/ARef: TM-TP1615L
1mg131.00€2mg173.00€5mg255.00€10mg374.00€25mg625.00€50mg890.00€100mg1,206.00€500mg2,422.00€Vamorolone
CAS:Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.Formula:C22H28O4Purity:99.54%Color and Shape:SolidMolecular weight:356.46Ref: TM-T17217
1mg34.00€2mg49.00€5mg74.00€10mg105.00€25mg178.00€50mg281.00€100mg421.00€200mg605.00€1mL*10mM (DMSO)82.00€Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66Polygalasaponin F
CAS:Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.Formula:C53H86O23Purity:98% - 99.83%Color and Shape:SolidMolecular weight:1091.24Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39Triptolide
CAS:Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Formula:C20H24O6Purity:97.19% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:360.40Ref: TM-T2179
1mg39.00€2mg52.00€5mg95.00€10mg123.00€25mg225.00€50mg315.00€100mg444.00€1mL*10mM (DMSO)75.00€Barlerin
CAS:Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injuryFormula:C19H28O12Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:448.42Ref: TM-T5S1632
1mg40.00€2mg52.00€5mg85.00€10mg115.00€25mg245.00€50mg354.00€100mg533.00€1mL*10mM (DMSO)92.00€TBK1/IKKε-IN-5
CAS:TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).Formula:C28H31N7O3Purity:98.77%Color and Shape:SolidMolecular weight:513.59Ref: TM-T7951
1mg88.00€5mg182.00€10mg269.00€25mg429.00€50mg587.00€100mg837.00€200mg1,125.00€1mL*10mM (DMSO)224.00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31Tyrosol
CAS:Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present mostFormula:C8H10O2Purity:99.24% - 99.86%Color and Shape:SolidMolecular weight:138.16PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69Ref: TM-T22115
5mg44.00€10mg71.00€25mg128.00€50mg178.00€100mg268.00€200mg389.00€1mL*10mM (DMSO)52.00€Zimlovisertib
CAS:Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4).Formula:C18H20FN3O4Purity:98.21%Color and Shape:SolidMolecular weight:361.37Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.
Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.6511-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€1mL*10mM (DMSO)133.00€Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Formula:C30H48O4Purity:98.1% - 99.98%Color and Shape:SolidMolecular weight:472.70Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51Sarsasapogenin
CAS:Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.Formula:C27H44O3Purity:90% - 99.73%Color and Shape:White Or Off-Withe PowderMolecular weight:416.64Obtusifolin
CAS:Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.Formula:C16H12O5Purity:99.78% - 99.99%Color and Shape:SolidMolecular weight:284.26Ref: TM-T4S0969
1mg66.00€5mg177.00€10mg264.00€25mg447.00€50mg623.00€100mg883.00€1mL*10mM (DMSO)177.00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.77Gossypin
CAS:Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.Formula:C21H20O13Purity:97.57% - 98.97%Color and Shape:SolidMolecular weight:480.38Aconine
CAS:1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.Formula:C25H41NO9Purity:99.61% - 99.93%Color and Shape:SolidMolecular weight:499.59Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.70Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formula:C21H28BN3O5Purity:95.52% - 99.46%Color and Shape:SolidMolecular weight:413.28Ref: TM-T6027
1mg46.00€5mg96.00€10mg140.00€25mg274.00€50mg439.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)95.00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Formula:C19H20O6Purity:99.6% - 99.71%Color and Shape:SolidMolecular weight:344.36Aristolochic acid A
CAS:Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.Formula:C17H11NO7Purity:99.85% - 99.97%Color and Shape:Yellow PowderMolecular weight:341.27Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormula:C9H9NOPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:147.173'-Sialyllactose sodium
CAS:3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis and can be used to study inflammation.Formula:C23H38NNaO19Purity:>99.99%Color and Shape:SolidMolecular weight:655.53(S)-(+)-Ibuprofen
CAS:(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Formula:C13H18O2Purity:99.51% - 99.86%Color and Shape:Colourless Crystalline SolidMolecular weight:206.28MnTBAP chloride
CAS:MnTBAP chloride: SOD mimetic, peroxynitrite scavenger, halves SOD-E. coli growth time, anti-inflammatory, may aid CKD research.Formula:C48H25ClMnN4O8Color and Shape:SolidMolecular weight:876.13GSK-872
CAS:GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity and inhibits kinase activity.
Formula:C19H17N3O2S2Purity:99.87% - 99.94%Color and Shape:SolidMolecular weight:383.491,3-Dibenzyl-5-fluorouracil
CAS:1,3-Dibenzyl-5-fluorouracil is a chemical inhibitor that suppresses the formation of osteoclasts, functioning by downregulating the signaling pathways of nuclear factor κB ligand receptor activator (Receptor activator of NF-κB ligand, RANKL) and macrophage colony-stimulating factor (M-CSF). This compound is used in the research of metabolic bone diseases.Formula:C18H15FN2O2Color and Shape:SolidMolecular weight:310.32Gatralimab
CAS:Gatralimab (anti-CD52 mAb) shows successful lymphocyte depletion & repopulation in Phase 1, supporting its study for relapsing MS.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDa
