Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(51 products)
- Calcium Channel(494 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(276 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2280 products of "Membrane Transporter/Ion Channel"
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L 691121
CAS:<p>L 691121 is a class III antiarrhythmic compound. It also blocks potassium currents.</p>Formula:C22H25ClN4O5SPurity:98%Color and Shape:SolidMolecular weight:492.98FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6BMS-986169
CAS:<p>BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, depression.</p>Formula:C23H27FN2O2Purity:97.61%Color and Shape:SolidMolecular weight:382.47AC-4
CAS:<p>AC-4 is a blocker of photoswitchable TRPV1 channel.</p>Formula:C26H25F3N4O2SColor and Shape:SolidMolecular weight:514.56ADX71441
CAS:<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Formula:C19H15ClF2N4O4Color and Shape:SolidMolecular weight:436.8Sudoterb free base
CAS:<p>Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.</p>Formula:C29H28F3N5OPurity:97.26% - 98.85%Color and Shape:SolidMolecular weight:519.56PHP 501 trifluoroacetate
CAS:<p>GABAA antagonist</p>Formula:C20H21N3OPurity:98%Color and Shape:SolidMolecular weight:319.4PZ-II-029
CAS:<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Formula:C18H15N3O3Purity:99.79%Color and Shape:SolidMolecular weight:321.33URAT1 inhibitor 1
CAS:<p>URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.</p>Formula:C19H15Br2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:569.29JYL-273
CAS:<p>JYL-273 is a TRPV1 agonist.</p>Formula:C28H39NO4SColor and Shape:SolidMolecular weight:485.68Licostinel
CAS:<p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>Formula:C8H3Cl2N3O4Purity:98.02%Color and Shape:SolidMolecular weight:276.03CGP36216 hydrochloride
CAS:<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Formula:C5H15ClNO2PColor and Shape:SolidMolecular weight:187.6MK-8153
CAS:<p>MK-8153: Selective, potent ROMK inhibitor, orally active, IC50: ROMK EP 5 μM, hERG EP 34 μM; potential diuretic.</p>Formula:C24H28N2O6Color and Shape:SolidMolecular weight:440.49Etidocaine Hydrochloride
CAS:<p>Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.</p>Formula:C17H29ClN2OPurity:99.86%Color and Shape:SolidMolecular weight:312.88GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42Kv3 modulator 4
CAS:<p>Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator .Cyclobutyl structure.</p>Formula:C20H24N2O4Purity:98%Color and Shape:SolidMolecular weight:356.42Glibornuride
CAS:<p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>Formula:C18H26N2O4SPurity:99.5%Color and Shape:SolidMolecular weight:366.48Kv3 modulator 3
CAS:<p>Kv3 modulator 3 is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels .has analgesic activity for use in the prophylaxis o or treatment of pain.</p>Formula:C19H18N4O3Purity:98%Color and Shape:SolidMolecular weight:350.37RS 5773
CAS:<p>RS 5773 is a benzothiazepine derivative with antianginal effects.</p>Formula:C29H33ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:541.1NaPi2b-IN-2
CAS:<p>NaPi2b-IN-2 (compound 5) serves as a potent inhibitor of the sodium-dependent transport protein 2b (SLC34A2, NaPi2b), exhibiting an IC50 of 38 nM against human</p>Formula:C41H47ClF3N5O5SPurity:98%Color and Shape:SolidMolecular weight:814.36Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Formula:C21H26N4O2Purity:99.54%Color and Shape:SolidMolecular weight:366.46Cavα2δ1&NET-IN-3
CAS:<p>Cavα2δ1&NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET).</p>Formula:C24H30N6O2SColor and Shape:SolidMolecular weight:466.6APS3
CAS:<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Formula:C18H7Cl2F6N5O5S2Color and Shape:SolidMolecular weight:622.31mGAT-IN-1
CAS:<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Formula:C28H34ClN3O2S2Color and Shape:SolidMolecular weight:544.17p-fin4
CAS:p-fin4, a peptide, inhibits STEP-GluA2 interaction, Ki 0.4 μM; may enhance cognition, has anxiolytic and antidepressant effects.Formula:C39H53N8O18PColor and Shape:SolidMolecular weight:952.85AMPA-IN-1
CAS:<p>AMPA-IN-1: Potent AMPA receptor inhibitor; key in regulating brain excitatory transmission and plasticity.</p>Formula:C23H12F2N4O2Color and Shape:SolidMolecular weight:414.36Dibutyryl-cGMP sodium
CAS:<p>Bt2cGMP sodium is a cGMP analog, activates PKG, inhibits platelet [3H]-arachidonate, and induces analgesia via K+ channels.</p>Formula:C18H24N5NaO9PPurity:98%Color and Shape:SolidMolecular weight:508.38TRPV2-selective blocker 1
CAS:<p>TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM.</p>Formula:C15H18OS2Color and Shape:SolidMolecular weight:278.43Risevistinel
CAS:<p>Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative</p>Formula:C14H23N3O4Purity:98%Color and Shape:SolidMolecular weight:297.35BMS-199264 hydrochloride
CAS:<p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>Formula:C26H32Cl2N4O4SPurity:99.86%Color and Shape:SolidMolecular weight:567.53Dimethylamiloride
CAS:<p>Dimethylamiloride is a specific inhibitor of antiporters [1].</p>Formula:C8H12ClN7OPurity:98%Color and Shape:SolidMolecular weight:257.68(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formula:C21H20ClNO6Purity:98%Color and Shape:SolidMolecular weight:417.84Co 102862
CAS:<p>Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.</p>Formula:C14H12FN3O2Purity:99.82%Color and Shape:SolidMolecular weight:273.26Sodium Channel inhibitor 4
CAS:<p>Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].</p>Formula:C19H18ClN3O4S2Purity:98%Color and Shape:SolidMolecular weight:451.95P2X3 antagonist 34
CAS:<p>Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.</p>Formula:C24H26F2N4O3Purity:98%Color and Shape:SolidMolecular weight:456.48ML-252 hydrochloride
CAS:<p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>Formula:C20H24N2OHClColor and Shape:SolidMolecular weight:344.9PF-05105679
CAS:<p>PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.</p>Formula:C26H21FN2O3Purity:99.84%Color and Shape:SolidMolecular weight:428.45SCS
CAS:<p>SCS is a GABAA receptor antagonist.</p>Formula:C14H12N2O3Purity:99.73%Color and Shape:SolidMolecular weight:256.26P-1075
CAS:<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Formula:C12H17N5Purity:99.85%Color and Shape:SolidMolecular weight:231.3Mesendogen
CAS:<p>Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7</p>Formula:C18H16ClF3N2OSPurity:99.66%Color and Shape:SolidMolecular weight:400.85LOE 908 hydrochloride
CAS:<p>Broad spectrum cation channel blocker</p>Formula:C41H49ClN2O9Purity:98%Color and Shape:SolidMolecular weight:749.293′-Acetate-ATP
CAS:<p>3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.</p>Formula:C12H18N5O14P3Color and Shape:SolidMolecular weight:549.22KCa1.1 channel activator-1
<p>A selective vascular KCa1.1 channel stimulator with CaV1.2 blocking ability and mild myorelaxant effects.</p>Formula:C25H16O10Color and Shape:SolidMolecular weight:476.39NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Formula:C13H13NaO3Purity:98%Color and Shape:SolidMolecular weight:240.23Pumaprazole
CAS:<p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>Formula:C19H22N4O2Purity:99.91%Color and Shape:SolidMolecular weight:338.4CLP257
CAS:<p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>Formula:C14H14FN3O2SPurity:99.5%Color and Shape:SolidMolecular weight:307.34Y-27152
CAS:<p>Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener.</p>Formula:C21H22N2O4Purity:98%Color and Shape:SolidMolecular weight:366.41S-Pantoprazole sodium trihydrate
CAS:<p>S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a</p>Formula:C16H20F2N3NaO7SPurity:98%Color and Shape:SolidMolecular weight:459.4Caroverine
CAS:Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.Formula:C22H27N3O2Color and Shape:SolidMolecular weight:365.47BPO-27 racemate
CAS:<p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>Formula:C26H18BrN3O6Purity:97.67% - 98.86%Color and Shape:SolidMolecular weight:548.34Iganidipine HCl
CAS:NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for the treatment of glaucoma.Formula:C28H40Cl2N4O6Color and Shape:SolidMolecular weight:599.55GSK3395879
CAS:<p>GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).</p>Formula:C20H15F4N3O5SPurity:98%Color and Shape:SolidMolecular weight:485.41CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76Aneratrigine
CAS:<p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>Formula:C19H20ClF2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:487.97Biricodar
CAS:<p>Biricodar is a P-glycoprotein and MRP-1 modulator.</p>Formula:C34H41N3O7Purity:98%Color and Shape:SolidMolecular weight:603.71Budiodarone
CAS:<p>Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.</p>Formula:C27H31I2NO5Color and Shape:SolidMolecular weight:703.35(R)-Elexacaftor
CAS:<p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>Formula:C26H34F3N7O4SPurity:98.991%Color and Shape:SolidMolecular weight:597.65Adipiplon
CAS:<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Formula:C18H18FN7Color and Shape:SolidMolecular weight:351.38Piperidine-4-sulfonic acid
CAS:<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Formula:C5H11NO3SPurity:98%Color and Shape:SolidMolecular weight:165.21NPEC-caged-(S)-AMPA
CAS:<p>AMPA receptor agonist</p>Formula:C16H17N3O8Purity:98%Color and Shape:SolidMolecular weight:379.32LG 83-6-05
CAS:<p>LG 83-6-05 is a novel kind of sodium channel blocking agent.</p>Formula:C21H30ClNO3SColor and Shape:SolidMolecular weight:411.99VU0463271
CAS:<p>VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.</p>Formula:C19H18N4OS2Purity:97.84% - 99.55%Color and Shape:SolidMolecular weight:382.5Aneratrigine hydrochloride
CAS:<p>Aneratrigine hydrochloride is a Nav 1.9 blocker that may be used to prevent or treat sodium channel blocker-related disorders.</p>Formula:C19H21Cl2F2N5O2S2Purity:98.37% - 99.16%Color and Shape:SolidMolecular weight:524.43MCT1-IN-3
CAS:<p>MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor.</p>Formula:C22H19N3O4Purity:99.35%Color and Shape:SoildMolecular weight:389.4AMG-0347
CAS:<p>AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.</p>Formula:C24H26F3N3O2Purity:99.93%Color and Shape:SolidMolecular weight:445.48Maralixibat Chloride
CAS:<p>Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.</p>Formula:C40H56ClN3O4SPurity:99.19% - 99.65%Color and Shape:SolidMolecular weight:710.41Bupivacaine hydrochloride monohydrate
CAS:<p>Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.</p>Formula:C18H31ClN2O2Purity:99.91%Color and Shape:SolidMolecular weight:342.9Kv3 modulator 1
CAS:<p>Kv3 modulator 1 is a voltage-gated potassium channel Kv3 modulator that can be used to study neurologic-level diseases.</p>Formula:C20H20N4O4Purity:99.41%Color and Shape:SolidMolecular weight:380.4L-DABA hydrobromide
CAS:<p>L-DABA hydrobromide (L-2,4-Diaminobutyric acid hydrobromide) , GABA transaminase inhibitor with antitumor and anticonvulsant activity.</p>Formula:C4H11BrN2O2Purity:99.11%Color and Shape:SolidMolecular weight:199.05Reldesemtiv
CAS:<p>Reldesemtiv (CK-2127107) boosts exercise capacity, targeting fast muscle troponin, EC50 3.4 μM.</p>Formula:C19H18F2N6OPurity:97.27%Color and Shape:SolidMolecular weight:384.38CE-224535
CAS:<p>CE-224535 (PF-04905428) is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies.</p>Formula:C22H29ClN4O6Purity:99.68%Color and Shape:SolidMolecular weight:480.94C 101248
CAS:<p>C 101248 (KCNK13-IN-1) is a selective and potent tandem pore halogen inhibitor of K+ channel 1 (THIK-1) inhibitor and a human and mouse KCNK13 inhibitor.</p>Formula:C15H12N6OPurity:99.14% - 99.31%Color and Shape:SolidMolecular weight:292.3EMD57033
CAS:<p>EMD57033 activates cardiac troponin C, enhances Ca2+ sensitivity to boost heart contraction.</p>Formula:C22H23N3O4SPurity:99.72% - >99.99%Color and Shape:SolidMolecular weight:425.5Funapide
CAS:<p>Funapide (TV 45070) is a potent Nav1.7 inhibitor, potentially treating inflammation and various pains.</p>Formula:C22H14F3NO5Purity:99.91%Color and Shape:SolidMolecular weight:429.35Soraprazan
CAS:<p>BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.</p>Formula:C21H25N3O3Purity:97.69% - 99.84%Color and Shape:SolidMolecular weight:367.44VGSCs-IN-1
CAS:<p>VGSCs-IN-1, a VGSC inhibitor and Riluzole analog, exhibits good blocking activity on Nav1.4 and can be used to study cellular excitability disorders.</p>Formula:C12H12F3N3OSPurity:99.88%Color and Shape:SolidMolecular weight:303.3CFTR corrector 4
CAS:<p>Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.</p>Formula:C29H27F2NO7Purity:99.32%Color and Shape:SolidMolecular weight:539.52LE135
CAS:<p>LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).</p>Formula:C29H30N2O2Purity:97.94%Color and Shape:SolidMolecular weight:438.56AMG2850
CAS:<p>AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).</p>Formula:C19H17F6N3OPurity:99.84%Color and Shape:SolidMolecular weight:417.35GABAA receptor agonist 1
<p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45AP-6
CAS:AP-6, a selective TMEM175 inhibitor, enhances lysosomal macromolecular catabolism by acutely inhibiting TMEM175, thus speeding up macrophage and other digestive activities. This compound holds potential for use in Parkinson's disease research due to its role in modulating lysosomal function.Formula:C16H14N4Color and Shape:SolidMolecular weight:262.31BMS-986163
CAS:<p>BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).</p>Formula:C23H28FN2O5PPurity:98%Color and Shape:SolidMolecular weight:462.45IAB15
CAS:<p>IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].</p>Formula:C15H14F3NO2Color and Shape:SolidMolecular weight:297.27T-Type calcium channel inhibitor 2
<p>Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).</p>Formula:C36H39FN4OSColor and Shape:SolidMolecular weight:594.78CAD204520
CAS:<p>CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).</p>Formula:C23H32F3N3O2Color and Shape:SolidMolecular weight:439.51PF-06462894
CAS:PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Formula:C18H23N3O3Purity:98%Color and Shape:SolidMolecular weight:329.39Caged MK801
CAS:<p>Caged MK801 (cMK801) is a selective, noncompetitive, and irreversible blocker of the NMDA receptor open channel. The NVOC cage is compatible in neuropharmacology and does not alter the intrinsic activity of the molecule.</p>Formula:C26H24N2O6Color and Shape:SolidMolecular weight:460.48P-gp modulator 2
<p>P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.</p>Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32ZK 93426 hydrochloride
CAS:<p>benzodiazepine receptor antagonist,competitive</p>Formula:C18H21ClN2O3Purity:98%Color and Shape:SolidMolecular weight:348.82LY3130481
CAS:<p>LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.</p>Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44Crinecerfont tosylate
CAS:<p>Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).</p>Formula:C34H36ClFN2O4S2Color and Shape:SolidMolecular weight:655.242Kv7.2/Kv7.3 agonist 1
CAS:<p>Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.</p>Formula:C14H14FN3O2Color and Shape:SolidMolecular weight:275.28O4I4
CAS:<p>O4I4 is an OCT4-inducing compound capable of activating endogenous OCT4 and its associated signaling pathways, shown anti-aging effects.</p>Formula:C15H20N2SPurity:99.74%Color and Shape:SolidMolecular weight:260.43-Methoxy PCE hydrochloride
CAS:<p>3-Methoxy PCE (3-MEO PCE) hydrochloride is an arylcyclohexylamine compound that functions as an NMDA receptor antagonist with a pKi value of 7.22.</p>Formula:C15H24ClNOColor and Shape:SolidMolecular weight:269.81WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Formula:C33H25N7OSColor and Shape:SolidMolecular weight:567.66LY 235959
CAS:<p>LY 235959 is a NMDA receptor antagonist.</p>Formula:C11H20NO5PPurity:98%Color and Shape:SolidMolecular weight:277.25Vormatrigine
CAS:<p>Vormatrigine effectively inhibits sodium channels (sodium channel).</p>Formula:C16H12F6N4O2Color and Shape:SolidMolecular weight:406.28H052
CAS:<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Formula:C21H15ClFN3O4SColor and Shape:SolidMolecular weight:459.88CFTR corrector 15
CAS:<p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>Formula:C24H22ClN5O2SColor and Shape:SolidMolecular weight:479.988-Prenylchrysin
CAS:<p>8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.</p>Formula:C20H18O4Color and Shape:SolidMolecular weight:322.354
