Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(51 products)
- Calcium Channel(493 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(276 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2277 products of "Membrane Transporter/Ion Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Riluzole-13C,15N2
CAS:<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formula:CC7H5F3OS15N2Color and Shape:SolidMolecular weight:237.18LY393615
<p>LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9</p>Purity:98%Color and Shape:Odour SolidMambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51XPO1-ligand-1
<p>XPO1-ligand-1 is a target protein ligand for XPO1, and it can be utilized in the synthesis of PROTAC XPO1 degrader-1.</p>Formula:C15H13ClF3N3O4Color and Shape:SolidMolecular weight:391.73P-gp inhibitor 13
<p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>Formula:C32H34O8Color and Shape:SolidMolecular weight:546.61KV1.3-IN-1
<p>KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,</p>Formula:C23H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.56Jingzhaotoxin-X
Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].Formula:C164H242N46O41S6Purity:98%Color and Shape:SolidMolecular weight:3706.35Aglafoline
CAS:<p>Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating</p>Formula:C28H28O8Color and Shape:SolidMolecular weight:492.52Verruculogen
CAS:<p>Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.</p>Formula:C27H33N3O7Purity:98%Color and Shape:White PowderMolecular weight:511.57NMDA receptor antagonist 2
CAS:<p>Potent, oral NR2B-selective NMDA receptor antagonist; IC50 of 1.0 nM, Ki of 0.88 nM; used for neuropathic pain and Parkinson's research.</p>Formula:C20H21N7OColor and Shape:SolidMolecular weight:375.436Bafilomycin B1
CAS:<p>Bafilomycin B1, a Streptomyces-derived macrolide, inhibits E. coli ATPase and fights Gram-positive bacteria and fungi.</p>Formula:C44H65NO13Purity:98%Color and Shape:White PowderMolecular weight:815.998AZD0095
CAS:<p>AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.</p>Formula:C27H32N8O2Purity:98.51%Color and Shape:SoildMolecular weight:500.6Apamin
CAS:<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Idrevloride
CAS:<p>Idrevloride (WO2016133967) inhibits ENaC, used in skin disorder research.</p>Formula:C30H49ClN8O7Color and Shape:SolidMolecular weight:669.223-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Formula:C3H10NO3PPurity:99.84%Color and Shape:Light Yellow LiquidMolecular weight:139.09NSC265473
CAS:<p>NSC265473 is an ABCG2 substrate.</p>Formula:C21H35N3O4SColor and Shape:SolidMolecular weight:425.58Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Formula:C15H14F3N3O4S2Purity:98% - >99.99%Color and Shape:Crystals From Dioxane SolidMolecular weight:421.41Dihydroisopimaric acid
CAS:<p>Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.</p>Formula:C20H32O2Color and Shape:SolidMolecular weight:304.47Camegliptin
CAS:<p>Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formula:C20H28FN3O3Color and Shape:SolidMolecular weight:377.45NSC799462
<p>NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.</p>Formula:C30H32F2N6O3SColor and Shape:SolidMolecular weight:594.68ANO1-IN-4
CAS:<p>ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.</p>Formula:C19H19BrF2N2O2SColor and Shape:SolidMolecular weight:457.33PF-04745637
CAS:<p>PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].</p>Formula:C27H32ClF3N2O2Purity:98.88% - 99.3%Color and Shape:SolidMolecular weight:509ETD001
CAS:<p>ETD001 is a long-acting ENaC inhibitor with an IC50 value of 57.5 nM in HBE cells. It is applicable for research in cystic fibrosis.</p>Formula:C41H57F6N9O16Color and Shape:SolidMolecular weight:1045.93(R)-AMPA
CAS:<p>inactive enantiomer of AMPA</p>Formula:C7H10N2O4Purity:98%Color and Shape:SolidMolecular weight:186.17TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.3618β-Glycyrrhetyl-3-O-sulfate
CAS:<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Formula:C30H46O7SColor and Shape:SolidMolecular weight:550.75Desalkylgidazepam
CAS:<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Formula:C15H11BrN2OColor and Shape:SolidMolecular weight:315.1717(S)-HETE
CAS:<p>Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473CP-628006
CAS:<p>CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.</p>Formula:C32H35F3N2O2Color and Shape:SolidMolecular weight:536.639Vanzacaftor
CAS:<p>Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.</p>Formula:C32H39N7O4SPurity:99.14%Color and Shape:SolidMolecular weight:617.76Chlorpropylate
CAS:<p>Chlorpropylate is an insecticide.</p>Formula:C17H16Cl2O3Purity:98%Color and Shape:SolidMolecular weight:339.21CFTR activator 2
CAS:<p>CFTR activator 2 (WAY-326769) is an activator of mutant CFTR (cystic fibrosis transmembrane conductance regulator), which increases ion transport activity and can be used for research into cystic fibrosis (CF).</p>Formula:C27H27N3O3Purity:99.70%Color and Shape:SolidMolecular weight:441.52kCAL01
CAS:<p>kCAL01 is a CAL inhibitor with a Ki value of 2.3 μM and holds potential for research in cystic fibrosis (CF).</p>Formula:C36H57N11O9Color and Shape:SolidMolecular weight:787.91L-R4W2
CAS:<p>Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.</p>Formula:C46H71N21O6Purity:98%Color and Shape:SolidMolecular weight:1014.24-Hydroxytolbutamide
CAS:<p>4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.</p>Formula:C12H18N2O4SPurity:98%Color and Shape:White To Off-WhiteMolecular weight:286.35AmmTX3
<p>KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.</p>Formula:C158H262N50O48S6Purity:98%Color and Shape:SolidMolecular weight:3822.47Detajmium bitartrate
CAS:<p>Detajmium bitartrate is used as an antiarrhythmic drug.</p>Formula:C31H47N3O9Color and Shape:SolidMolecular weight:605.72S-WJM992
<p>S-WJM992 (compound 10ahb) serves as an antiparasitic agent, effectively inhibiting ATPase activity in high [Na+] environments. It also significantly counteracts parasites resistant to PfATP4 inhibitors. Additionally, S-WJM992 acts as a potential transmission blocker by impeding gamete development and halting the transmission of parasites to mosquitoes during blood feeding.</p>Formula:C22H18ClFN6O3Color and Shape:SolidMolecular weight:468.87AChE/Aβ-IN-2
<p>AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.</p>Formula:C20H25ClN4Color and Shape:SolidMolecular weight:356.89Antimalarial agent 41
<p>Antimalarial agent 41 (Compound 17) exhibits antimalarial activity by inhibiting the malaria parasite Plasmodium falciparum, with IC50 values of 40 nM for NF54 strain and 76 nM for K1 strain. This compound acts as an inhibitor of P. falciparum phosphatidylinositol-4-kinase β (PfPI4K) and hERG channels, with IC50 values of 53 nM and 3 μM, respectively. Additionally, Antimalarial agent 41 shows cytotoxicity against CHO cells, with an IC50 of 34 μM. It can improve malaria infections and demonstrates favorable pharmacokinetic properties in mouse models.</p>Formula:C19H18F3N5Molecular weight:373.15143ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Formula:C106H178N40O32S7Purity:98%Color and Shape:White Lyophilised SolidMolecular weight:2749NF110
CAS:<p>P2X3 antagonist</p>Formula:C41H32N6NaO17S4Purity:98%Color and Shape:SolidMolecular weight:1031.97TRPV4 antagonist 3
CAS:<p>TRPV4 antagonist 3 is a TRPV4 antagonist (p IC 50 = 8.4).</p>Formula:C20H18F4N4O3SColor and Shape:SolidMolecular weight:470.44Venturicidin A
CAS:<p>Venturicidin A is a macrolide antibiotic.</p>Formula:C41H67NO11Purity:98%Color and Shape:SolidMolecular weight:749.97PF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Formula:C35H35Cl3F3N7O3S2Purity:99.16%Color and Shape:SolidMolecular weight:829.18Hyp9
CAS:<p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>Formula:C18H26O5Color and Shape:SolidMolecular weight:322.40AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34N-hydroxy Riluzole
CAS:<p>N-hydroxy Riluzole, a metabolite of riluzole, is mainly produced by CYP1A2 in human liver.</p>Formula:C8H5F3N2O2SColor and Shape:SolidMolecular weight:250.20Foslevcromakalim
CAS:<p>Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].</p>Formula:C16H19N2O6PColor and Shape:SolidMolecular weight:366.31Brevetoxin B
CAS:<p>Brevetoxin B, a polyketide neurotoxin from Karenia, affects sodium channels causing neurotoxic shellfish poisoning. IC50=15nM.</p>Formula:C50H70O14Color and Shape:SolidMolecular weight:895.09612,14-Dichlorodehydroabietic acid
CAS:<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Formula:C20H26Cl2O2Color and Shape:SolidMolecular weight:369.33URAT1/GLUT9-IN-1
<p>URAT1/GLUT9-IN-1 (compound 29) effectively inhibits urate transporter 1 (URAT1) with an IC50 value of 2.01 μM and glucose transporter 9 (GLUT9) with an IC50 of 18.21 μM. This compound exhibits favorable pharmacokinetic properties and oral bioavailability, making it useful for research in gout and hyperuricemia.</p>SG-094
CAS:<p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>Formula:C30H29NO3Purity:97.06%Color and Shape:SoildMolecular weight:451.564-oxo-2-Nonenal
CAS:<p>4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.</p>Formula:C9H14O2Color and Shape:SolidMolecular weight:154.209S-Bioallethrin
CAS:<p>S-Bioallethrin is a pure S-form of Bioallethrin.</p>Formula:C19H26O3Purity:98%Molecular weight:302.41Anisatin
<p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>Formula:C15H20O8Color and Shape:SolidMolecular weight:328.317CHET3
CAS:<p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>Formula:C21H21N5O3SPurity:99.64% - >99.99%Color and Shape:SoildMolecular weight:423.49SC 4453
CAS:<p>SC 4453 is a digoxin analog and a cardiac glycoside derivative.</p>Formula:C41H64N2O12Color and Shape:SolidMolecular weight:776.965Transdermal Peptide Disulfide
CAS:<p>TD 1 peptide, an 11-amino acid, binds ATP1B1's C-terminus, enhancing transdermal drug delivery.</p>Formula:C40H64N14O16S2Purity:98%Color and Shape:SolidMolecular weight:1061.15GSK2332255B
CAS:<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Formula:C18H19ClFN3O3SColor and Shape:SolidMolecular weight:411.88Nav1.7-IN-8
CAS:<p>Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.</p>Formula:C21H12ClF2N5O4S2Color and Shape:SolidMolecular weight:535.93Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formula:C9H6Cl6O3SPurity:99.86%Color and Shape:SolidMolecular weight:406.93AZD-3161
CAS:<p>AZD-3161 is a sodium channel regulator for pain.</p>Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.43WAY-326766
CAS:<p>WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).</p>Formula:C21H23N3O5Purity:98.76%Color and Shape:SolidMolecular weight:397.42α-Amylase/α-Glucosidase-IN-10
<p>α-Amylase/α-Glucosidase-IN-10 (compound 5d) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 30.39 μM and 65.1 μM, respectively, indicating potential antidiabetic properties. In ADMET (absorption, distribution, metabolism, excretion, and toxicity) predictions, it shows high gastrointestinal (GI) absorption but functions as a substrate for P-glycoprotein (P-gp) and does not cross the blood-brain barrier (BBB), which may pose a risk of central nervous system side effects.</p>Formula:C33H40ClN5O5Molecular weight:621.2718Anticancer agent 108
<p>Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both</p>Formula:C18H9NO5S2Color and Shape:SolidMolecular weight:383.43-Hydroxy desalkylflurazepam
CAS:<p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>Formula:C15H10ClFN2O2Color and Shape:SolidMolecular weight:304.7Vesnarinone HCl
<p>Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.</p>Formula:C22H26ClN3O4Purity:99.17%Color and Shape:SoildMolecular weight:431.91GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Color and Shape:Odour SolidJYL-79
CAS:<p>JYL-79 is an agonist of the vanilloid receptor.</p>Formula:C26H36N2O4SColor and Shape:SolidMolecular weight:472.64Pe1b
<p>Pe1b (μ-TrTx-Pe1b) is a selective inhibitor of the NaV1.7 channel, exhibiting an inhibitory concentration 50 (IC50) value of 167 nanomolar (nM) [1].</p>Formula:C175H237N47O49S6Purity:98%Color and Shape:SolidMolecular weight:3975.43PDZ1 Domain inhibitor peptide
CAS:<p>Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95</p>Formula:C38H61N9O11Purity:98%Color and Shape:SolidMolecular weight:819.94AZ1422
<p>AZ1422 is a selective MCT4 inhibitor, applicable for cancer research.</p>Formula:C31H40N2O6Molecular weight:536.28864Yaddle1
Yaddle1 is an agonist of the mechanically sensitive ion channel protein Piezo1, with a half-maximal effective concentration (MEC50) of 0.40 μM. It significantly induces Ca2+ influx in T cells, prompting T cell activation responses. Yaddle1 is applicable in vaccine adjuvant research.Formula:C14H8ClF3N4OSMolecular weight:372.00594Caloxin 2A1 acetate
<p>Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.</p>Formula:C66H95N19O24Purity:98.2%Color and Shape:SolidMolecular weight:1538.57Concanamycin B
CAS:<p>Concanamycin B, a macrolide, inhibits V-ATPases (IC50 = 5 nM), blocks vacuole acidification, affects bone resorption, CD8 T cells, and MHC II in B cells.</p>Formula:C45H73NO14Color and Shape:SolidMolecular weight:852.072ORI-TRN-002
<p>ORI-TRN-002 is an AQP4 inhibitor with an IC50 value of 3 μM. It is applicable in the field of brain edema research.</p>Formula:C10H7N5OMolecular weight:213.06506MRS4596
<p>MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.</p>Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42P-gp inhibitor 23
<p>P-gp inhibitor 23 (compound 14F) is an effective inhibitor of both P-gp and CYP3A4, with an EC50 of 28 nM for P-gp and an IC50 of 223 nM for CYP3A4.</p>Formula:C40H37N5O6Molecular weight:683.27438Oleoyl-D-lysine
CAS:<p>Oleoyl-D-lysine: lipid-based GlyT2 inhibitor, eases neuropathic pain in mice, safe, non-sedative, no respiratory depression.</p>Formula:C24H46N2O3Color and Shape:SolidMolecular weight:410.63APETx2 TFA
<p>APETx2 TFA from sea anemone is a selective ASIC3 inhibitor with a 63 nM IC50, reversing acid and inflammatory pain.</p>Formula:C198H281F3N54O62S6Color and Shape:SolidMolecular weight:4675.02Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Color and Shape:Odour Solid(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Formula:C6H11NO2Color and Shape:SolidMolecular weight:129.16Chlorotoxin
CAS:<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formula:C158H249N53O47S11Purity:98%Color and Shape:SolidMolecular weight:3995.71Pyrazolam
CAS:<p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>Formula:C16H12BrN5Color and Shape:SolidMolecular weight:354.2Ampullosporin A
CAS:<p>Ampullosporin A is a peptaibol-type polypeptide isolated from the fungus Sepedonium ampullosporum (HKI-0053), exhibiting neuromodulatory activity. It inhibits hyperactivity induced by the NMDA receptor antagonist MK-801 and ameliorates social behavior abnormalities caused by subchronic ketamine treatment. Ampullosporin A modulates glutamate receptor activity without affecting dopamine D1 and D2 receptors.</p>Formula:C77H127N19O19Color and Shape:SolidMolecular weight:1622.95GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formula:C185H273N49O45S6Purity:98%Color and Shape:SolidMolecular weight:4095.843,4-Dihydroxypyrovalerone HCl
CAS:<p>3,4-Dihydroxypyrovalerone HCl is an analog of Pyrovalerone. Pyrovalerone inhibits the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET).</p>Formula:C15H22ClNO3Color and Shape:SolidMolecular weight:299.79(±)8(9)-EpETE
CAS:<p>(±)8(9)-EpETE ((±)8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by CYP450 epoxygenase.1.2 In rat and rabbit liver microsomes.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45ADWX 1 TFA
<p>ADWX 1 TFA is a novel peptide that potently targets and inhibits the Kv1.3 channel, with an IC50 of 1.89 pM. It specifically suppresses the activity of the Kv1.3 channel, in addition to inhibiting initial calcium signaling and NF-κB activation. This compound has been shown to ameliorate symptoms in rats with experimental autoimmune encephalomyelitis (EAE). ADWX 1 TFA is utilized in research focused on T-cell-mediated autoimmune diseases.</p>Formula:C169H281N57O46S7·xC2HF3O2Color and Shape:SolidMolecular weight:4071.85 (free base)Fipronil sulfone
CAS:<p>Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.</p>Formula:C12H4Cl2F6N4O2SPurity:98%Color and Shape:SolidMolecular weight:453.14Chrodrimanin B
CAS:<p>Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.</p>Formula:C27H32O8Color and Shape:SolidMolecular weight:484.545Sinapine hydroxide
CAS:<p>Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.</p>Formula:C16H25NO6Color and Shape:SolidMolecular weight:327.377Guangxitoxin 1E
CAS:<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formula:C178H248N44O45S7Purity:98%Color and Shape:SolidMolecular weight:3948.61CW2158
<p>CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.</p>Formula:C14H8F4N4O2Molecular weight:340.05834Nav1.7-IN-18
<p>Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, demonstrating analgesic effects in transgenic mice with inherited erythromelalgia (IEM).</p>Formula:C30H33Cl2F2NO4Color and Shape:SolidMolecular weight:580.49Nitrazolam
CAS:<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32Digoxigenin Monodigitoxoside
CAS:<p>Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.</p>Formula:C29H44O8Color and Shape:SolidMolecular weight:520.663KNa1.1-IN-2
CAS:<p>KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.</p>Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.4Ebio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4Mepivacaine hydrochloride
CAS:<p>Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.</p>Formula:C15H22N2O·HClPurity:98.76% - 99.94%Color and Shape:White Or Off White Crystalline PowderMolecular weight:282.81GeX-2
CAS:<p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>Formula:C103H169N43O27Color and Shape:SolidMolecular weight:2441.72Linoleic Acid Amide
CAS:<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Formula:C18H33NOPurity:98%Color and Shape:SolidMolecular weight:279.461-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:<p>1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.</p>Formula:C6H8N2OPurity:99.92%Color and Shape:SolidMolecular weight:124.14Fumitremorgin C
CAS:<p>Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.</p>Formula:C22H25N3O3Purity:98%Color and Shape:SolidMolecular weight:379.45Albanin A
<p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>Formula:C20H18O6Color and Shape:SolidMolecular weight:354.358c-Met-IN-23
<p>c-Met-IN-23 (Compound 12g) functions as a c-Met inhibitor with an IC50 of 0.052 μM against c-Met. It also inhibits the MDR1 and MRP1/2 pumps in cancerous HepG2 and BxPC3 cells. As such, c-Met-IN-23 serves as an anticancer agent.</p>Formula:C16H13N7OMolecular weight:319.11816JTS-653
CAS:<p>JTS-653 is a potent TRPV1 antagonist, effective in reducing chronic pain unresponsive to NSAIDs.</p>Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.44CBP-1008
<p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>Color and Shape:Odour SolidNF279
CAS:<p>P2X1 antagonist</p>Formula:C49H36N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1407.17AVLX-125
CAS:<p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>Formula:C62H104N10O29Color and Shape:SolidMolecular weight:1453.54NHE-1-IN-2
NHE-1-IN-2 (compound 7g) is a potent NHE-1 inhibitor with an IC50 of 0.78 μM. It mitigates left ventricular systolic dysfunction in mouse models of heart failure.Formula:C23H20ClN3O3Color and Shape:SolidMolecular weight:421.11932Oleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Formula:C28H44N2O2Purity:99.88%Color and Shape:SolidMolecular weight:440.66Myomodulin
CAS:<p>Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the</p>Formula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12Cinazepam
CAS:<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Formula:C19H14BrClN2O5Color and Shape:SolidMolecular weight:465.68BCRP-IN-2
CAS:<p>BCRP-IN-2 is a compound with BCRP inhibitory activity, exhibiting enhanced inhibition of BCRP upon UV activation. It serves as a valuable probe for studying interactions between quinazoline amine derivatives and BCRP, and it stimulates ATP hydrolysis of the BCRP transporter, leading to increased mitoxantrone accumulation in BCRP-overexpressing H460/MX20 cells.</p>Formula:C19H13N7Color and Shape:SolidMolecular weight:339.35JC-229
CAS:<p>JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).</p>Formula:C20H14Cl4N2O3SPurity:97.14%Color and Shape:SolidMolecular weight:504.21(S)-ABT 102
CAS:<p>N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.</p>Formula:C21H24N4OPurity:99.65% - 99.77%Color and Shape:SoildMolecular weight:348.44GSK2798745
CAS:<p>GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).</p>Formula:C25H28N6O3Color and Shape:SolidMolecular weight:460.53Pinacidil monohydrate
CAS:<p>Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.</p>Formula:C13H21N5OPurity:99.94% - 99.98%Color and Shape:PowderMolecular weight:263.34AQP4 (205-215)
CAS:<p>AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4). This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).</p>Formula:C48H75N13O17SColor and Shape:SolidMolecular weight:1138.25Prilocaine acetate
<p>Prilocaine acetate, an amino amide compound, functions as a Na/K-ATPase inhibitor, exhibiting neurotoxic effects [1] [2].</p>Formula:C15H24N2O3Color and Shape:SolidMolecular weight:280.36AR-C141990 hydrochloride
CAS:<p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>Formula:C26H29ClN4O4SColor and Shape:SolidMolecular weight:529.05Dendrotoxin K
CAS:<p>Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.</p>Formula:C294H462N84O75S6Color and Shape:SolidMolecular weight:6559.66UCL 1684 dibromide
CAS:<p>apamin-sensitive Ca2+-activated K+ channel (KCa2.1) blocker</p>Formula:C34H30Br2N4Purity:98%Color and Shape:SolidMolecular weight:654.45Milbemycin A4
CAS:<p>Milbemycin A4, a distinguished member of the macrocyclic lactones family featuring a unique spiroketal group, is derived from the fermentation of the soil bacterium Streptomyces hygroscopicus subsp. aureolacrimosus. It acts by enhancing the opening of glutamate and GABA-gated chloride channels, rendering it effective as both a nematocide and insecticide.</p>Formula:C32H46O7Color and Shape:SolidMolecular weight:542.713Dalazatide HCl
<p>Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,</p>Color and Shape:SolidMolecular weight:4317.53 (Free base)P2X3 antagonist 39
<p>P2X3 antagonist 39 (compound 26a) is a selective P2X3 receptor antagonist with an IC50 of 54.9 nM. It is utilized in the study of neuropathic pain models.</p>Color and Shape:Odour SolidHuwentoxin I
CAS:<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Formula:C161H246N48O44S6Purity:98%Color and Shape:SolidMolecular weight:3750.36TRPV4 antagonist 4
CAS:<p>Potent TRPV4 blocker with 22.65 nM IC50; inhibits current and aids acute lung injury.</p>Formula:C28H32Cl2N6OColor and Shape:SolidMolecular weight:539.50TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Formula:C11H8ClN3Color and Shape:SolidMolecular weight:217.66Dofetilide N-oxide
CAS:<p>Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug.</p>Formula:C19H27N3O6S2Purity:98%Color and Shape:SolidMolecular weight:457.56BuChE-IN-9
<p>BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM.</p>Formula:C28H34N4O2Color and Shape:SolidMolecular weight:458.6Anticonvulsant agent 8
<p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>Formula:C15H11N5OColor and Shape:SolidMolecular weight:277.28CPI1
<p>CPI1 is an effective and highly specific inhibitor of multidrug resistance protein 1 (MRP1). It exhibits inhibitory activity against MRP1 at the nanomolar level (Ki: 100 nM) and has minimal effect on P-glycoprotein (Pgp). CPI1 competes with LTC4 for binding to the same site on MRP1, inhibiting ATP hydrolysis and substrate transport. It is useful in research related to drug delivery and addressing cancer chemotherapy resistance.</p>Formula:C111H131N23O30SColor and Shape:SolidMolecular weight:2299.43Phe-Met-Arg-Phe amide trifluoroacetate
CAS:<p>Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.</p>Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81Lifastuzumab
CAS:<p>Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative and is the primary immunogen for sulfonamide hypersensitivity reactions.</p>Purity:97% (SDS-PAGE); 99.5% (SEC-HPLC) - 97% (SDS-PAGE); 99.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaRusfertide
CAS:<p>Rusfertide, a peptide mimetic of natural hepcidin, targets and degrades ferroportin, thereby reducing serum iron and transferrin saturation, which helps regulate red blood cell production. It ameliorates conditions such as polycythemia vera, β-thalassemia, and hereditary hemochromatosis [1] [2].</p>Formula:C114H181N27O28S2Color and Shape:SolidMolecular weight:2441.95TNP-ATP triethylammonium salt
CAS:<p>P2X receptor antagonist</p>Formula:C40H77N12O19P3Purity:98%Color and Shape:SolidMolecular weight:1123.042GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:SolidMolecular weight:395.71RN-1665
CAS:<p>RN-1665 is a potent and selective TRPV4 receptor antagonist.</p>Formula:C20H24F5N3O3S2Purity:>99.99%Color and Shape:SoildMolecular weight:513.54HG1 Toxin
<p>HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.</p>Formula:C337H503N103O97S6Molecular weight:7736.59176GDC-0334
CAS:<p>GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.</p>Formula:C24H19F8N5O3SColor and Shape:SolidMolecular weight:609.52,4,6-Tri-tert-butylphenol
CAS:<p>2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.</p>Formula:C18H30OPurity:99.55%Color and Shape:SolidMolecular weight:262.43Urease-IN-19
<p>Urease-IN-19 (Compound 3c) is a potent inhibitor of urease, demonstrating an IC50 value of 2.7 µM. It shows potential for use in research related to kidney stones and gastric ulcers.</p>Formula:C17H16FN3SColor and Shape:SolidMolecular weight:313.39Ebio2
<p>Ebio2 is an effective activator of KCNQ2.</p>Formula:C17H19F2N3O2Color and Shape:SolidMolecular weight:335.349Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formula:C18H27N5OColor and Shape:SolidMolecular weight:329.448Margatoxin
CAS:<p>KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.</p>Formula:C178H286N52O50S7Purity:98%Color and Shape:SolidMolecular weight:4178.96Lei-Dab7
CAS:Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.Formula:C141H236N46O39S6Purity:98%Color and Shape:SolidMolecular weight:3392.06P2X4 antagonist-4
<p>P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.</p>Formula:C27H22FN3O4SColor and Shape:SolidMolecular weight:503.545BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418D-GsMTx4
<p>TRPC1/6 & Piezo2 inhibitor; mimics GsMTx4; blocks ~70% mechanosensitive currents; aids in mouse heart attack models; protease-resistant.</p>Color and Shape:Soildω-Agatoxin IVA
CAS:<p>Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.</p>Formula:C217H360N68O60S10Purity:98%Color and Shape:SolidMolecular weight:5202.25GX 201
CAS:<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Formula:C25H27ClF4N2O4SPurity:99.81%Color and Shape:SolidMolecular weight:563ABCB1-IN-1
<p>ABCB1-IN-1 (compound 3) is a potent inhibitor of ABCB1 that promotes cell apoptosis.</p>Formula:C36H33F3FeN2O4PSColor and Shape:SolidMolecular weight:733.54α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4Tacrine hydrochloride
CAS:<p>Tacrine: a cholinergic agonist, anticholinesterase; inhibits AChE/BChE with IC50s of 31/25.6 nM.</p>Formula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.73Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formula:C20H25ClN2O5·C6H6O3SH2OColor and Shape:SolidMolecular weight:1224.18Ouabagenin
CAS:<p>Ouabagenin, a naturally occurring LXR ligand with selective agonist activity, functions as an EC 3.6.3.9 (Na(+)/K(+)-transport ATPase) inhibitor [1] [2].</p>Formula:C23H34O8Color and Shape:SolidMolecular weight:438.51GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Formula:C11H16N6OPurity:99.79%Color and Shape:SoildMolecular weight:248.28AQP3-IN-1
CAS:<p>AQP3-IN-1 (compounds 3), an AQP3 inhibitor, exhibits an IC 50 of 8.91 μM and effectively inhibits melanoma cell proliferation [1].</p>Formula:C11H9AuCl2N2Color and Shape:SolidMolecular weight:437.08Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45PptT-IN-4
<p>PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.</p>Formula:C17H23N3Purity:98%Color and Shape:SolidMolecular weight:269.38Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formula:C29H33FN2O6Purity:98.95% - 99.50%Color and Shape:SolidMolecular weight:524.585-Tridecanol
CAS:<p>5-Tridecanol blocks ion flux in sodium channels.</p>Formula:C13H28OPurity:97.87%Color and Shape:SolidMolecular weight:200.3617(R)-Resolvin D1
CAS:<p>Resolvins are anti-inflammatory lipids from EPA and DHA. Resolvin D1, made from DHA, and its aspirin-triggered epimer 17(R)-RvD1, inhibit acute inflammation.</p>Formula:C22H32O5Color and Shape:SolidMolecular weight:376.493P-gp inhibitor 15
<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>Formula:C35H60N2O4Color and Shape:SolidMolecular weight:572.86Crofelemer
CAS:<p>Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.</p>Color and Shape:SolidAnalgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Formula:C22H25ClN2O2Color and Shape:SolidMolecular weight:384.9AQP4 (201-220) TFA
<p>AQP4 (201-220) TFA is an encephalitogenic epitope of AQP-4. This compound can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal abnormalities, and lesions at the grey/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Color and Shape:Odour SolidCalcium Ionophore I
CAS:<p>Calcium Ionophore I has a wide range of applications in life science related research.</p>Formula:C38H72N2O8Color and Shape:SolidMolecular weight:685.0Charybdotoxin
CAS:<p>Specific inhibitor of the big conductance Ca2+-activated K+ channel.</p>Formula:C176H277N57O55S7Purity:98%Color and Shape:SolidMolecular weight:4295.95ATP synthase inhibitor 2 TFA
<p>ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL.</p>Formula:C23H23F3N2O5SColor and Shape:SolidMolecular weight:496.5JAMI1001A
CAS:<p>JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.</p>Formula:C16H17F3N4O3SColor and Shape:SolidMolecular weight:402.39Phe-Met-Arg-Phe, amide
CAS:<p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76Tariquidar dimesylate
CAS:<p>Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.</p>Formula:C80H94N8O25S4Purity:98%Color and Shape:SolidMolecular weight:1695.9L-Palmitoylcarnitine TFA
<p>L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia & inhibits KATP channels via Kir6.2 interaction.</p>Formula:C25H46F3NO6Color and Shape:SolidMolecular weight:513.63Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Purity:96.97%Color and Shape:SolidRoquefortine C
CAS:<p>Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins</p>Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Formula:C19H13ClN2O2SPurity:99.86%Color and Shape:SolidMolecular weight:368.84P-gp inhibitor 14
CAS:<p>Compound 8a, also known as P-gp inhibitor 14, demonstrates high affinity as a P-gp inhibitor and effectively reverses P-gp-mediated multidrug resistance (EC 50 = 48.74 nM). Additionally, this compound exhibits a weak inhibitory effect on CYP3A4 activity [1].</p>Formula:C37H38N2O8Color and Shape:SolidMolecular weight:638.71MS7710
<p>MS7710 is a brain-penetrant inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. It reduces Ih current by inhibiting HCN channels, thereby decreasing the activity of dopamine neurons in the ventral tegmental area (VTA). MS7710 effectively improves social interaction deficits and reward-related cognitive flexibility in mouse models of chronic social defeat stress (CSDS) and shows promise for depression research.</p>Color and Shape:Odour SolidATP Synthesis-IN-2
<p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>Color and Shape:Odour SolidWay 125971
CAS:<p>Way 125971 is a bioactive chemcial.</p>Formula:C22H28N4O5S2Color and Shape:SolidMolecular weight:492.61Chlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Formula:C160H250F3N53O49S11Color and Shape:SolidMolecular weight:4109.74AQP4 (205-215) TFA
<p>AQP4 (205-215) TFA is a fragment of the water channel protein-4 (AQP4). AQP4 acts as an autoimmune antigen in neuromyelitis optica, upregulating and presenting in B cells upon binding with CD40. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).</p>Color and Shape:Odour SolidHomocarnosine
CAS:<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Formula:C10H16N4O3Color and Shape:SolidMolecular weight:240.26Quinine hemisulfate hydrate
CAS:<p>Quinine hemisulfate hydrate: anti-malaria, derived from cinchona bark, inhibits mouse Slo3 channels with IC50 169 μM.</p>Formula:C20H26N2O3H2O4S·H2OColor and Shape:SolidMolecular weight:391.47S-Sulfo-L-cysteine sodium salt
CAS:<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Formula:C3H6NNaO5S2Purity:99.88%Color and Shape:SolidMolecular weight:223.2LY-466195
CAS:<p>LY-466195 is a competitive antagonist of GLUK5 receptor.</p>Formula:C16H24F2N2O4Color and Shape:SolidMolecular weight:346.37Trans (2,3)-Dihydrotetrabenazine
CAS:<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Formula:C19H29NO3Purity:98%Color and Shape:SolidMolecular weight:319.44MMK 1
CAS:<p>Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.</p>Formula:C75H123N19O18SPurity:98%Color and Shape:SolidMolecular weight:1610.97TP-050
CAS:<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Formula:C16H15ClF2N6OColor and Shape:SolidMolecular weight:380.78RuBi-GABA
CAS:<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.8AHN-683
CAS:<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72NF864
CAS:<p>NF864, a suramin analog, is a P2X1 receptor inhibitor.</p>Formula:C57H28N6Na12O41S12Purity:98%Color and Shape:SolidMolecular weight:2113.5BeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formula:C174H261N51O52S6Purity:98%Color and Shape:SolidMolecular weight:4091.65Spongionellol A
<p>Spongionellol A inhibits MDR1, selectively kills prostate cancer through caspase-induced apoptosis, and aids cancer research.</p>Formula:C27H40O9Color and Shape:SolidMolecular weight:508.6
