Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 295 products of "Potassium Channel"
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Clofilium tosylate
CAS:Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.Formula:C28H44ClNO3SPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:510.17VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Formula:C20H32BrClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:447.844-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formula:C5H6N2Purity:91.61%Color and Shape:SolidMolecular weight:94.11VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit
Formula:C20H22ClFN4O2SPurity:98.1%Color and Shape:SoildMolecular weight:436.93Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formula:C16H16ClN3O3SPurity:98.97% - 99.83%Color and Shape:SolidMolecular weight:365.83Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formula:C19H24ClN3O3Purity:99.3%Color and Shape:SolidMolecular weight:377.87Ref: TM-T16110
1mg37.00€5mg79.00€10mg111.00€25mg178.00€50mg288.00€100mg414.00€200mg583.00€1mL*10mM (DMSO)88.00€Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formula:C21H17ClF3N3O3Purity:99.86%Color and Shape:SolidMolecular weight:451.83Ref: TM-T15207
1mg62.00€5mg116.00€10mg170.00€25mg283.00€50mg424.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)128.00€Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formula:C32H41NO2Purity:98.76% - 99.75%Color and Shape:SolidMolecular weight:471.67DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFormula:C22H28Cl2O4Purity:99.79% - 99.87%Color and Shape:SolidMolecular weight:427.36Ref: TM-T10979
2mg39.00€5mg57.00€10mg87.00€25mg177.00€50mg301.00€100mg485.00€200mg690.00€1mL*10mM (DMSO)63.00€NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formula:C17H16ClN7Purity:99.55%Color and Shape:SolidMolecular weight:353.81Brompheniramine maleate
CAS:Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formula:C16H19BrN2·C4H4O4Purity:99.80%Color and Shape:Crystal PowderMolecular weight:435.31Glipizide
CAS:Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.Formula:C21H27N5O4SPurity:99.67% - 99.75%Color and Shape:SolidMolecular weight:445.54IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormula:C31H32N4O2Purity:98.9%Color and Shape:SolidMolecular weight:492.61Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Formula:C17H26N2OPurity:97.75% - >99.99%Color and Shape:SolidMolecular weight:274.40Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:SolidMolecular weight:593.22Ref: TM-T1073
5mg38.00€10mg52.00€25mg87.00€50mg117.00€100mg170.00€200mg250.00€500mg424.00€1mL*10mM (DMSO)55.00€Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.99%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00AZD 7009
CAS:AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.Formula:C23H34N4O5Purity:98.42% - 98.51%Color and Shape:SoildMolecular weight:446.54
