Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 276 products of "Potassium Channel"
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Rosuvastatin
CAS:<p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>Formula:C22H28FN3O6SPurity:95.24% - 99.8%Color and Shape:SolidMolecular weight:481.54Levosimendan
CAS:<p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>Formula:C14H12N6OPurity:99.37% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28QO-40
CAS:<p>QO-40 is a KCNQ2/3 potassium channels activator.</p>Formula:C18H11ClF3N3OPurity:99.57%Color and Shape:SolidMolecular weight:377.75H3B-120
CAS:<p>H3B-120: selective, competitive CPS1 inhibitor with anti-cancer properties. IC50: 1.5 μM, Ki: 1.4 μM.</p>Formula:C19H24N4O2SPurity:99.03% - 99.2%Color and Shape:SolidMolecular weight:372.48CLP290
CAS:<p>CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatric</p>Formula:C19H21FN4O3SPurity:99.93% - >99.99%Color and Shape:SolidMolecular weight:404.46BMS-191011
CAS:<p>BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models</p>Formula:C16H10ClF3N2O3Purity:97.43%Color and Shape:SolidMolecular weight:370.71Tetrandrine
CAS:<p>Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.</p>Formula:C38H42N2O6Purity:99.61% - 99.94%Color and Shape:White SolidMolecular weight:622.75BL-1249
CAS:<p>BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).</p>Formula:C17H17N5Purity:98% - 98.25%Color and Shape:SolidMolecular weight:291.35VU590
CAS:<p>VU590 is an inhibitor of extrarenal medullary potassium ROMK.VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.</p>Formula:C24H32N4O7Purity:98.06%Color and Shape:SolidMolecular weight:488.53HUP30
CAS:<p>HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.</p>Formula:C14H15N3O3SPurity:99.96%Color and Shape:SolidMolecular weight:305.35Doxapram
CAS:<p>Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels.</p>Formula:C24H30N2O2Purity:99.42%Color and Shape:SolidMolecular weight:378.51Dofetilide D4
CAS:<p>Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication.</p>Formula:C19H27N3O5S2Purity:98%Color and Shape:SolidMolecular weight:445.59Repaglinide D5
CAS:<p>Repaglinide D5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for treatment type-2 diabetes mellitus.</p>Formula:C27H36N2O4Purity:98%Color and Shape:SolidMolecular weight:457.62LY 303511
CAS:<p>LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.</p>Formula:C19H18N2O2Purity:98%Color and Shape:SolidMolecular weight:306.36Meclofenamic acid
CAS:<p>Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.</p>Formula:C14H11Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:296.15AVE-0118
CAS:<p>AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.</p>Formula:C30H29N3O3Purity:97.04% - 98.93%Color and Shape:SolidMolecular weight:479.57ML402
CAS:<p>ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.</p>Formula:C14H14ClNO2SPurity:99.71%Color and Shape:SolidMolecular weight:295.78ICA
CAS:<p>ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).</p>Formula:C13H10N4SPurity:99.68%Color and Shape:SolidMolecular weight:254.31UK 78282 hydrochloride
CAS:<p>UK-78282 hydrochloride, a Kv1.3 blocker.UK-78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.</p>Formula:C29H36ClNO2Purity:99.68%Color and Shape:SolidMolecular weight:466.05TWIK-1/TREK-1-IN-2
CAS:<p>TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values</p>Formula:C20H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:386.45B-TPMF
CAS:<p>B-TPMF is a highly efficient and selective KCa2.1 channel inhibitor with an IC50 of 31 nM, interacting with serine residue at position 293 to inhibit KCa2.1.</p>Formula:C19H24N6O2Purity:99.82%Color and Shape:SolidMolecular weight:368.43SCH-23390 maleate
CAS:<p>SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,</p>Formula:C21H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:403.86Vernakalant
CAS:<p>Vernakalant (RSD-1235) is a mixed ion channel blocker.</p>Formula:C20H31NO4Purity:98%Color and Shape:SolidMolecular weight:349.46CM-TPMF
CAS:<p>CM-TPMF is a highly efficient and potent activator of the K(Ca)2.1 channel, Ser293 in the transmembrane segment 5, neurological disorders.</p>Formula:C16H17ClN6O2Purity:99.94%Color and Shape:SolidMolecular weight:360.8HN37
CAS:<p>HN37, KCNQ2 activator (EC50=37 nM). Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C20H21FN2O2Purity:99.27%Color and Shape:SolidMolecular weight:340.39Pinacidil
CAS:<p>Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and</p>Formula:C13H19N5Purity:99.9%Color and Shape:SolidMolecular weight:245.32VU0405601
CAS:<p>VU0405601 is a hERG channel activator that protects against drug-induced cardiac arrhythmias.</p>Formula:C17H13BrN2O2Purity:99.16%Color and Shape:SolidMolecular weight:357.2Nifekalant hydrochloride
CAS:<p>Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM.</p>Formula:C19H28ClN5O5Purity:99.91%Color and Shape:SolidMolecular weight:441.91Almokalant
CAS:<p>Almokalant: Class III antiarrhythmic, K+ channel blocker, inhibits Ikr current.</p>Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49Aprikalim
CAS:<p>Aprikalim opens KATP channels, protects the heart, and at high doses, dilates blood vessels.</p>Formula:C12H16N2OS2Purity:99.42% - 99.90%Color and Shape:SolidMolecular weight:268.4TWIK-1/TREK-1-IN-1
CAS:<p>Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and</p>Formula:C21H24F3NO3Purity:98%Color and Shape:SolidMolecular weight:395.42AVE1231
CAS:<p>AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.</p>Formula:C20H27N3O4SPurity:98.03%Color and Shape:SolidMolecular weight:405.51GAL-021 sulfate
CAS:<p>GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.</p>Formula:C11H24N6O5SPurity:99.92%Color and Shape:SolidMolecular weight:352.41TRAM 39
CAS:<p>TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.</p>Formula:C20H14ClNPurity:99.97%Color and Shape:SolidMolecular weight:303.78RY796
CAS:<p>RY796 is a selective voltage-gated potassium (KV2) channel inhibitor that inhibits KV2.1 and KV2.2, used in research on neurological disorders.</p>Formula:C21H27N3O2Purity:98.59%Color and Shape:SolidMolecular weight:353.46Psora 4
CAS:<p>Psora 4 (5-(4-Phenylbutoxy)psoralen) is a Kv1.3 blocker and a caloric restriction mimetic.</p>Formula:C21H18O4Color and Shape:SolidMolecular weight:334.37Vernakalant Hydrochloride
CAS:<p>Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.</p>Formula:C20H32ClNO4Purity:99.89%Color and Shape:SolidMolecular weight:385.93Amsacrine
CAS:<p>Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.</p>Formula:C21H19N3O3SPurity:99.2%Color and Shape:Yellow Crystalline Powder SolidMolecular weight:393.46DMP-543
CAS:<p>DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.</p>Formula:C26H18F2N2OPurity:99.89%Color and Shape:SolidMolecular weight:412.43TASK-1-IN-1
CAS:<p>TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.</p>Formula:C22H20N2O2Purity:99.57%Color and Shape:SoildMolecular weight:344.41MK-0448
CAS:<p>MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.</p>Formula:C24H21FN4O2SPurity:99.25% - 99.79%Color and Shape:SolidMolecular weight:448.51CyPPA
CAS:<p>CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.</p>Formula:C16H23N5Purity:99.88%Color and Shape:SolidMolecular weight:285.39Sipatrigine
CAS:<p>Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.</p>Formula:C15H16Cl3N5Purity:98.64% - 99.77%Color and Shape:SolidMolecular weight:372.68RL648_81
CAS:<p>RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.</p>Formula:C17H17F4N3O2Purity:99.82%Color and Shape:SolidMolecular weight:371.33SKA-111
CAS:<p>SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.</p>Formula:C12H10N2SPurity:99.9%Color and Shape:SolidMolecular weight:214.29ZTZ240
CAS:<p>ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.</p>Formula:C12H8ClFN2OPurity:99.89%Color and Shape:SolidMolecular weight:250.66ZM 226600
CAS:<p>ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.</p>Formula:C16H14F3NO4SPurity:99.87%Color and Shape:SolidMolecular weight:373.35PD-118057
CAS:<p>PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.</p>Formula:C21H17Cl2NO2Purity:99.16% - 99.97%Color and Shape:SolidMolecular weight:386.27UK 66914
CAS:<p>UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.</p>Formula:C18H24N4O3SPurity:99.75%Color and Shape:SolidMolecular weight:376.47(+)-KCC2 blocker 1
CAS:<p>(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).</p>Formula:C22H25NO5SPurity:99.88%Color and Shape:SolidMolecular weight:415.5
