Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 304 products of "Potassium Channel"
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Nigericin sodium salt
CAS:Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.Formula:C40H67NaO11Purity:98.2% - 99.52%Color and Shape:SolidMolecular weight:746.94Atpenin A5
CAS:Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).Formula:C15H21Cl2NO5Purity:97.33% - 99.91%Color and Shape:SolidMolecular weight:366.24LY 303511 hydrochloride
CAS:LY 303511 hydrochloride is a potent mTOR inhibitorFormula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82VU0071063
CAS:VU0071063 is a Kir6.2/SUR1 activator.Formula:C18H22N4O2Purity:99.33%Color and Shape:SolidMolecular weight:326.39Mitiglinide Calcium
CAS:Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-Formula:(C19H24NO3)2·CaPurity:99.83%Color and Shape:White Crystal PosderMolecular weight:668.88Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.5% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Senicapoc
CAS:Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.Formula:C20H15F2NOPurity:95.7% - 99.47%Color and Shape:SolidMolecular weight:323.34E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurity:99.31% - 99.87%Color and Shape:SolidMolecular weight:474.44Allocryptopine
CAS:Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.Formula:C21H23NO5Purity:99.41% - ≥95%Color and Shape:SolidMolecular weight:369.415-Hydroxydecanoate sodium
CAS:5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.Formula:C10H19NaO3Purity:99.24% - 99.89%Color and Shape:SolidMolecular weight:210.25VU0810464
CAS:VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.Formula:C18H21ClFN3OPurity:99.62%Color and Shape:SolidMolecular weight:349.83Ref: TM-T7899
1mg44.00€5mg89.00€10mg142.00€25mg231.00€50mg309.00€100mg411.00€200mg560.00€1mL*10mM (DMSO)99.00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35Mitiglinide calcium hydrate
CAS:Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.Formula:C38H52CaN2O8Purity:98.97% - 99.96%Color and Shape:White SolidMolecular weight:704.91A2793
CAS:A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.Formula:C13H12ClNO3Purity:98.54%Color and Shape:SolidMolecular weight:265.69ML365
CAS:ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).Formula:C22H20N2O3Purity:98.78%Color and Shape:SolidMolecular weight:360.41Azimilide Dihydrochloride
CAS:Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.Formula:C23H30Cl3N5O3Purity:97.59% - ≥95%Color and Shape:SolidMolecular weight:530.88O-Nornuciferine
CAS:O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.Formula:C18H19NO2Purity:99.86%Color and Shape:SolidMolecular weight:281.35ML213
CAS:ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,Formula:C17H23NOPurity:>99.99%Color and Shape:SolidMolecular weight:257.37Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Formula:C16H18N2O3Purity:99.74%Color and Shape:SolidMolecular weight:286.33Ref: TM-TQ0150
1mg50.00€2mg73.00€5mg94.00€10mg142.00€25mg318.00€50mg472.00€100mg683.00€1mL*10mM (DMSO)104.00€Almitrine mesylate
CAS:Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.Formula:C28H37F2N7O6S2Purity:99.96%Color and Shape:CoaMolecular weight:669.76NS6180
CAS:NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Ref: TM-T1752
1mg34.00€2mg47.00€5mg66.00€10mg101.00€25mg212.00€50mg346.00€100mg515.00€1mL*10mM (DMSO)66.00€Kv2-IN-A1
CAS:Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.Formula:C20H17ClN4OSPurity:98.83%Color and Shape:SolidMolecular weight:396.89Quinine hydrochloride dihydrate
CAS:Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.Formula:C20H24N2O2·HCl·2H2OPurity:99.91%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:396.91Yoda 1
CAS:Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.Formula:C13H8Cl2N4S2Purity:98% - 99.98%Color and Shape:SolidMolecular weight:355.27Ref: TM-T7506
1mg44.00€2mg57.00€5mg90.00€10mg109.00€25mg219.00€50mg424.00€100mg620.00€500mg1,314.00€1mL*10mM (DMSO)88.00€A2764 dihydrochloride
CAS:A2764 dihydrochloride is a highly selective inhibitor of TRESK.Formula:C15H21Cl3N2OPurity:99.05%Color and Shape:SolidMolecular weight:351.7Paederosidic acid methyl ester
CAS:Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
Formula:C19H26O12SPurity:99.67% - 99.91%Color and Shape:SolidMolecular weight:478.47(±)-Naringenin
CAS:(±)-Naringenin (Naringenine) is a natural product.Formula:C15H12O5Purity:98.06%Color and Shape:SolidMolecular weight:272.25Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37ICA-105574
CAS:ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Ref: TM-T9009
1mg40.00€5mg87.00€10mg137.00€25mg281.00€50mg444.00€100mg650.00€200mg888.00€1mL*10mM (DMSO)96.00€Nateglinide
CAS:Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.Formula:C19H27NO3Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:317.42Branaplam
CAS:Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
Formula:C22H27N5O2Purity:98.28% - 99.72%Color and Shape:SolidMolecular weight:393.48Rosuvastatin
CAS:Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formula:C22H28FN3O6SPurity:95.24% - 99.95%Color and Shape:SolidMolecular weight:481.54Levosimendan
CAS:Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.
Formula:C14H12N6OPurity:99.37% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28QO-40
CAS:QO-40 is a KCNQ2/3 potassium channels activator.Formula:C18H11ClF3N3OPurity:99.57%Color and Shape:SolidMolecular weight:377.75Endoxifen (Z-isomer)
CAS:Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.Formula:C25H27NO2Purity:99.19% - 99.81%Color and Shape:SolidMolecular weight:373.49Ref: TM-T2280
1mg34.00€5mg66.00€10mg88.00€25mg167.00€50mg259.00€100mg389.00€200mg563.00€1mL*10mM (DMSO)75.00€Phe-Met-Arg-Phe, amide acetate
Phe-Met-Arg-Phe amide acetate (ED50=23 nM) triggers K+ current in caudodorsal neurons, co-localizes with neuropeptide Y in brain areas.Formula:C31H46N8O6SPurity:99.4%Color and Shape:SolidMolecular weight:658.82SKA-31
CAS:SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).Formula:C11H8N2SPurity:99.38%Color and Shape:SolidMolecular weight:200.26H3B-120
CAS:H3B-120: selective, competitive CPS1 inhibitor with anti-cancer properties. IC50: 1.5 μM, Ki: 1.4 μM.Formula:C19H24N4O2SPurity:99.03% - 99.2%Color and Shape:SolidMolecular weight:372.48Ref: TM-T11529
1mg38.00€2mg50.00€5mg80.00€10mg118.00€25mg250.00€50mg404.00€100mg647.00€200mg893.00€1mL*10mM (DMSO)88.00€BL-1249
CAS:BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).Formula:C17H17N5Purity:98% - 98.25%Color and Shape:SolidMolecular weight:291.35Ref: TM-T14666
1mg50.00€5mg105.00€10mg167.00€25mg245.00€50mg334.00€100mg587.00€500mg1,215.00€1mL*10mM (DMSO)146.00€Doxapram
CAS:Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels.Formula:C24H30N2O2Purity:99.42%Color and Shape:SolidMolecular weight:378.51VU590
CAS:VU590 is an inhibitor of extrarenal medullary potassium ROMK.VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.Formula:C24H32N4O7Purity:98.06%Color and Shape:SolidMolecular weight:488.53Eleclazine
CAS:Eleclazine (GS-6615) is a novel and selective voltage-gated sodium channel inhibitor with antiarrhythmic properties that reduces peak sodium current (INaP).Formula:C21H16F3N3O3Purity:98.67%Color and Shape:SolidMolecular weight:415.37Repaglinide D5
CAS:Repaglinide D5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for treatment type-2 diabetes mellitus.Formula:C27H36N2O4Purity:98%Color and Shape:SolidMolecular weight:457.62Dofetilide D4
CAS:Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication.Formula:C19H27N3O5S2Purity:98%Color and Shape:SolidMolecular weight:445.59Meclofenamic acid
CAS:Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.Formula:C14H11Cl2NO2Purity:99.98%Color and Shape:SolidMolecular weight:296.15CPK20
CAS:CPK20 is a potent and selective inhibitor of the KCNT1 channel, useful for epilepsy research.Formula:C23H24F6N2O2SColor and Shape:SolidMolecular weight:506.50LY 303511
CAS:LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.Formula:C19H18N2O2Purity:98%Color and Shape:SolidMolecular weight:306.36HN37
CAS:HN37, KCNQ2 activator (EC50=37 nM). Affordable Excellence: Reliable Quality You Can TrustFormula:C20H21FN2O2Purity:99.27%Color and Shape:SolidMolecular weight:340.39UK 78282 hydrochloride
CAS:UK-78282 hydrochloride, a Kv1.3 blocker.UK-78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.Formula:C29H36ClNO2Purity:99.89%Color and Shape:SolidMolecular weight:466.05ML402
CAS:ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.Formula:C14H14ClNO2SPurity:99.71%Color and Shape:SolidMolecular weight:295.78Ref: TM-T16109
5mg48.00€10mg75.00€25mg138.00€50mg215.00€100mg318.00€200mg444.00€1mL*10mM (DMSO)49.00€
