HIF/HIF Prolyl-Hydroxylase
Hypoxia-Inducible Factor (HIF) is a transcription factor that plays a critical role in cellular responses to low oxygen levels (hypoxia). HIF activity is tightly regulated by HIF prolyl-hydroxylases, which target HIF for degradation under normoxic conditions. Inhibitors of HIF prolyl-hydroxylase can stabilize HIF, promoting the expression of genes involved in angiogenesis, erythropoiesis, and metabolism. These inhibitors are of great interest in treating conditions such as anemia, ischemic diseases, and cancer. At CymitQuimica, we offer HIF/HIF prolyl-hydroxylase inhibitors to support your research in hypoxia biology, cancer therapy, and metabolic regulation.
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Molidustat
CAS:1154028-82-6
Molidustat (BAY 85-3934)(BAY-85-3934), an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH), stimulates erythropoietin (EPO) …
Formula:
C13H14N8O2
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
314.3
Ref: TM-T2652
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 313.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Fenbendazole
CAS:43210-67-9
Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.
Formula:
C15H13N3O2S
Purity:
100%
Color and Shape:
White To Yellowish Powder
Molecular weight:
299.35
Ref: TM-T1141
| 50mg | 39.00 € | ||
| 100mg | 50.00 € | ||
| 200mg | 62.00 € | ||
| 500mg | 88.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Chloramphenicol
CAS:56-75-7
Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and …
Formula:
C11H12Cl2N2O5
Purity:
99.6% - 99.89%
Color and Shape:
Needles Or Elongated Plates From Water Or Ethylene Dichloride Solid
Molecular weight:
323.13
Ref: TM-T1205
| 1g | 57.00 € | ||
| 5g | 67.00 € | ||
| 10g | 88.00 € | ||
| 500mg | 46.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Tilorone dihydrochloride
CAS:27591-69-1
Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
Formula:
C25H36Cl2N2O3
Purity:
98% - 99.86%
Color and Shape:
Orange Yellow Crystal Powder
Molecular weight:
483.47
Ref: TM-T0244
| 100mg | 63.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
SYP-5
CAS:1384268-04-5
SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.
Formula:
C18H16O3S
Purity:
98.31%
Color and Shape:
Solid
Molecular weight:
312.38
Ref: TM-T13050
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Albendazole
CAS:54965-21-8
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of …
Formula:
C12H15N3O2S
Purity:
98.76%
Color and Shape:
Colorless Crystals Solid
Molecular weight:
265.33
Ref: TM-T1152
| 50mg | 52.00 € | ||
| 100mg | 57.00 € | ||
| 200mg | 69.00 € | ||
| 500mg | 92.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Deferoxamine Mesylate
CAS:138-14-7
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.
Formula:
C26H52N6O11S
Purity:
94.68% - 99.80%
Color and Shape:
Solid
Molecular weight:
656.79
Ref: TM-T1637
| 1g | 140.00 € | ||
| 50mg | 37.00 € | ||
| 100mg | 53.00 € | ||
| 500mg | 85.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Oltipraz
CAS:64224-21-1
Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.
Formula:
C8H6N2S3
Purity:
100% - 99.56%
Color and Shape:
Solid
Molecular weight:
226.34
Ref: TM-T0153
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 122.00 € | ||
| 200mg | 155.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
(-)-Hydroxycitric acid lactone
CAS:27750-13-6
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor …
Formula:
C6H6O7
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
190.11
Ref: TM-T12045
| 1mg | 74.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 154.00 € | ||
| 10mg | 235.00 € | ||
| 25mg | 394.00 € | ||
| 50mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Hydralazine hydrochloride
CAS:304-20-1
Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.
Formula:
C8H9ClN4
Purity:
99.1% - 99.86%
Color and Shape:
Yellow Crystals White Crystalline Solid
Molecular weight:
196.64
Ref: TM-T1613
| 1g | 102.00 € | ||
| 200mg | 42.00 € | ||
| 500mg | 79.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Daprodustat
CAS:960539-70-2
Daprodustat (GSK1278863) is a HIF-prolyl hydroxylase inhibitor.
Formula:
C19H27N3O6
Purity:
97% - 99.82%
Color and Shape:
Solid
Molecular weight:
393.43
Ref: TM-T3197
| 2mg | 54.00 € | ||
| 5mg | 76.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 295.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
EHP-101
CAS:1818428-24-8
EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related …
Formula:
C28H35NO3
Purity:
99.22%
Color and Shape:
Solid
Molecular weight:
433.58
Ref: TM-T13289
| 1mg | 105.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 610.00 € | ||
| 50mg | 848.00 € | ||
| 100mg | 1,142.00 € | ||
| 1mL*10mM (DMSO) | 249.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
PT2399
CAS:1672662-14-4
PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.
Formula:
C17H10F5NO4S
Purity:
98.8% - 99.07%
Color and Shape:
Solid
Molecular weight:
419.32
Ref: TM-T12675L
| 1mg | 96.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 346.00 € | ||
| 25mg | 625.00 € | ||
| 50mg | 922.00 € | ||
| 100mg | 1,290.00 € | ||
| 1mL*10mM (DMSO) | 253.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Hydroxycitric acid tripotassium hydrate
CAS:6100-05-6
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits HIF, has antioxidation, anti-inflammation, and anti-tumor …
Formula:
C6H7K3O8
Purity:
95%
Color and Shape:
White Solid Crystalline
Molecular weight:
324.41
Ref: TM-T11589
| 1g | 62.00 € | ||
| 5g | 93.00 € | ||
| 10g | 123.00 € | ||
| 500mg | 48.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Glucosamine hydrochloride
CAS:66-84-2
Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance …
Formula:
C6H13NO5·HCl
Purity:
99.07%
Color and Shape:
White Solid Crystalline
Molecular weight:
215.63
Ref: TM-T2941
| 500mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Roxadustat
CAS:808118-40-3
Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic …
Formula:
C19H16N2O5
Purity:
99% - 99.94%
Color and Shape:
Solid
Molecular weight:
352.34
Ref: TM-T2515
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 111.00 € | ||
| 500mg | 261.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Glucosamine
CAS:3416-24-8
Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of …
Formula:
C6H13NO5
Purity:
99.80% - 99.80%
Color and Shape:
Coa
Molecular weight:
179.17
Ref: TM-T0429
| 50mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Vadadustat
CAS:1000025-07-9
Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for …
Formula:
C14H11ClN2O4
Purity:
99.09% - 99.4%
Color and Shape:
Solid
Molecular weight:
306.7
Ref: TM-T4651
| 1mg | 49.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 366.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
HIF-2α-IN-2
CAS:1672666-82-8
HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).
Formula:
C17H13F2NO4S
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
365.35
Ref: TM-T11561
| 1mg | 69.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 431.00 € | ||
| 100mg | 598.00 € | ||
| 200mg | 805.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Minocycline hydrochloride
CAS:13614-98-7
Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.
Formula:
C23H28ClN3O7
Purity:
100% - 99.89%
Color and Shape:
Bright Yellow-Orange Amorphous Solid Crystalline Yellow
Molecular weight:
493.94
Ref: TM-T1101
| 25mg | 45.00 € | ||
| 50mg | 54.00 € | ||
| 100mg | 67.00 € | ||
| 200mg | 89.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
