PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 164 products of "PPAR"
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GW590735
CAS:<p>GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.</p>Formula:C23H21F3N2O4SPurity:99.53%Color and Shape:SolidMolecular weight:478.48PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Formula:C23H28FN7O3Color and Shape:SolidMolecular weight:469.51GQ-16
CAS:<p>GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.</p>Formula:C19H16BrNO3SPurity:99.84%Color and Shape:SolidMolecular weight:418.3CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Formula:C26H33NO5Purity:99.84%Color and Shape:SolidMolecular weight:439.54PPAR α/PPARA Protein, Human, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.</p>Color and Shape:Lyophilized PowderMolecular weight:31.36 kDa (predicted)PPAR α/PPARA Protein, Mouse, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.</p>Color and Shape:Lyophilized PowderMolecular weight:31.49 kDa (predicted)Balaglitazone
CAS:<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Formula:C20H17N3O4SPurity:99.74%Color and Shape:SolidMolecular weight:395.43Ciprofibrate
CAS:<p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>Formula:C13H14Cl2O3Purity:99.63% - >99.99%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:289.15Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35MK-886
CAS:<p>MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).</p>Formula:C27H34ClNO2SPurity:99.23% - 99.84%Color and Shape:SolidMolecular weight:472.08LJ570
CAS:<p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>Formula:C27H22O3Purity:99.64%Color and Shape:SolidMolecular weight:394.46Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Formula:C22H28ClNO5Purity:98.82%Color and Shape:SolidMolecular weight:421.91Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Formula:C21H23NO4Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:353.41Seladelpar
CAS:<p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>Formula:C21H23F3O5SPurity:99.18% - 99.41%Color and Shape:SolidMolecular weight:444.46Norathyriol
CAS:<p>Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.</p>Formula:C13H8O6Purity:99.35% - 99.55%Color and Shape:SolidMolecular weight:260.2Pirinixic Acid
CAS:<p>Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.</p>Formula:C14H14ClN3O2SPurity:98.27% - 99.92%Color and Shape:SolidMolecular weight:323.8Bilobetin
CAS:<p>Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.</p>Formula:C31H20O10Purity:97.74% - 99.69%Color and Shape:SolidMolecular weight:552.48GW 501516
CAS:<p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.50OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Formula:C44H70O16Purity:99.46% - ≥95%Color and Shape:SolidMolecular weight:855.02BMS-687453
CAS:<p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>Formula:C22H21ClN2O6Purity:99.4%Color and Shape:SolidMolecular weight:444.86Licarin B
CAS:<p>1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.</p>Formula:C20H20O4Purity:99.82% - ≥95%Color and Shape:SolidMolecular weight:324.37Eupatilin
CAS:<p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>Formula:C18H16O7Purity:98.53% - 99%Color and Shape:SolidMolecular weight:344.32GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formula:C13H9ClN2O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:276.68SR1664
CAS:<p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>Formula:C33H29N3O5Purity:98.02%Color and Shape:SolidMolecular weight:547.6FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Formula:C13H10Cl2N2O4SPurity:98.25% - 99.5%Color and Shape:SolidMolecular weight:361.2Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Formula:C33H40O15Purity:97.82% - 98.3%Color and Shape:SolidMolecular weight:676.66Glabrone
CAS:<p>Glabrone shows antiviral activity against influenza virus.</p>Formula:C20H16O5Purity:99.08% - 99.55%Color and Shape:SolidMolecular weight:336.34GW6471
CAS:<p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>Formula:C35H36F3N3O4Purity:98.23% - 99.55%Color and Shape:SolidMolecular weight:619.67Palmitelaidic Acid
CAS:<p>Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.</p>Formula:C16H30O2Purity:99.76%Color and Shape:SolidMolecular weight:254.41NSC-87877 disodium
CAS:<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42SR 16832
CAS:<p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>Formula:C17H12ClN3O4Purity:99.6%Color and Shape:SolidMolecular weight:357.75GW0742
CAS:<p>GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).</p>Formula:C21H17F4NO3S2Purity:99.75% - 99.85%Color and Shape:SolidMolecular weight:471.49CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Formula:C34H43N3O3Purity:98.3% - 99.61%Color and Shape:SolidMolecular weight:541.72SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Formula:C16H11ClF3N3O2SPurity:99.74%Color and Shape:SolidMolecular weight:401.79Raspberry ketone
CAS:<p>1.</p>Formula:C10H12O2Purity:99.84% - 99.89%Color and Shape:White Solid CrystallineMolecular weight:164.2Fisetin
CAS:<p>Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.</p>Formula:C15H10O6Purity:94.14% - 99.05%Color and Shape:Yellow To Brown Crystalline PowderMolecular weight:286.24Ginsenoside Rh1
CAS:<p>Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.</p>Formula:C36H62O9Purity:99% - 99.77%Color and Shape:SolidMolecular weight:638.87Alpinetin
CAS:<p>Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.</p>Formula:C16H14O4Purity:98.39%Color and Shape:SolidMolecular weight:270.28Glabridin
CAS:<p>Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.</p>Formula:C20H20O4Purity:99.78% - 99.99%Color and Shape:Light Yellow Powder Insoluble In WaterMolecular weight:324.37Convallatoxin
CAS:<p>Convallatoxin is a natural product.</p>Formula:C29H42O10Purity:99.27% - 99.53%Color and Shape:Prisms From Methanol + Ether SolidMolecular weight:550.64Methyl oleanonate
CAS:<p>3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.</p>Formula:C31H48O3Purity:98.99%Color and Shape:SolidMolecular weight:468.71Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Agrimol B
CAS:<p>1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.</p>Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:SolidMolecular weight:682.75(E/Z)-Elafibranor
CAS:<p>GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.</p>Formula:C22H24O4SPurity:98.36%Color and Shape:SolidMolecular weight:384.49Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36GW1929
CAS:<p>GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).</p>Formula:C30H29N3O4Purity:98.1% - 98.21%Color and Shape:SolidMolecular weight:495.57Bocidelpar
CAS:<p>Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.</p>Formula:C25H27F3N2O3Purity:97.77%Color and Shape:SolidMolecular weight:460.49Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Formula:C24H27NO5SPurity:98% - 99.8%Color and Shape:Yellow SolidMolecular weight:441.54Tetradecylthioacetic acid
CAS:<p>Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.</p>Formula:C16H32O2SPurity:99.93%Color and Shape:SolidMolecular weight:288.49
