PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 170 products of "PPAR"
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GW590735
CAS:GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.Formula:C23H21F3N2O4SPurity:99.53%Color and Shape:SolidMolecular weight:478.48GQ-16
CAS:GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Formula:C19H16BrNO3SPurity:99.84%Color and Shape:SolidMolecular weight:418.3Ref: TM-T21955
10mg39.00€25mg80.00€50mg116.00€100mg187.00€200mg280.00€500mg449.00€1mL*10mM (DMSO)35.00€Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Formula:C20H17N3O4SPurity:99.74%Color and Shape:SolidMolecular weight:395.43CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Formula:C26H33NO5Purity:99.84%Color and Shape:SolidMolecular weight:439.54PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:31.49 kDa (predicted)Ref: TM-TMPY-06837
5µg109.00€10µg174.00€20µg289.00€50µg576.00€100µg1,017.00€200µg1,718.00€500µg4,207.00€PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:31.36 kDa (predicted)Ref: TM-TMPY-06830
5µg110.00€10µg177.00€20µg289.00€50µg576.00€100µg1,007.00€200µg1,700.00€500µg3,631.00€SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formula:C17H12ClN3O4Purity:99.6%Color and Shape:SolidMolecular weight:357.75GW0742
CAS:GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).Formula:C21H17F4NO3S2Purity:99.75% - 99.85%Color and Shape:SolidMolecular weight:471.49CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purity:98.3% - 99.61%Color and Shape:SolidMolecular weight:541.72Ref: TM-TQ0120
1mg34.00€5mg74.00€10mg105.00€25mg200.00€50mg319.00€100mg485.00€500mg1,035.00€1mL*10mM (DMSO)89.00€Angeloylgomisin H
CAS:Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Formula:C28H36O8Purity:99.84% - 99.95%Color and Shape:SolidMolecular weight:500.58Ref: TM-TN1018
1mg52.00€5mg111.00€10mg172.00€25mg290.00€50mg420.00€100mg577.00€1mL*10mM (DMSO)149.00€Cinnamyl alcohol
CAS:Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Formula:C9H10OPurity:99.00%Color and Shape:Colourless LiquidMolecular weight:134.18SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Formula:C16H11ClF3N3O2SPurity:99.74%Color and Shape:SolidMolecular weight:401.79Clofibrate
CAS:Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.Formula:C12H15ClO3Purity:98.77%Color and Shape:Oil LiquidMolecular weight:242.70Raspberry ketone
CAS:1.Formula:C10H12O2Purity:99.84% - 99.89%Color and Shape:White Solid CrystallineMolecular weight:164.2Fisetin
CAS:Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Formula:C15H10O6Purity:94.14% - 99.05%Color and Shape:Yellow To Brown Crystalline PowderMolecular weight:286.24Ginsenoside Rh1
CAS:Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.Formula:C36H62O9Purity:99% - 99.64%Color and Shape:SolidMolecular weight:638.87Alpinetin
CAS:Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.Formula:C16H14O4Purity:98.39%Color and Shape:SolidMolecular weight:270.28Oleuropein
CAS:Oleuropein is an antioxidant polyphenol isolated from olive leaf.Formula:C25H32O13Purity:98% - 99.95%Color and Shape:Brown PowderMolecular weight:540.51EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formula:C21H27ClO5Purity:99% - 99.67%Color and Shape:SolidMolecular weight:394.89Ref: TM-T6829
2mg35.00€5mg50.00€10mg77.00€25mg127.00€50mg202.00€100mg303.00€200mg449.00€1mL*10mM (DMSO)51.00€Glabridin
CAS:Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.Formula:C20H20O4Purity:99.78% - 99.99%Color and Shape:Light Yellow Powder Insoluble In WaterMolecular weight:324.37Convallatoxin
CAS:Convallatoxin is a natural product.Formula:C29H42O10Purity:99.27% - 99.53%Color and Shape:Prisms From Methanol + Ether SolidMolecular weight:550.64Elafibranor
CAS:Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) withFormula:C22H24O4SPurity:98.42% - 98.78%Color and Shape:SolidMolecular weight:384.49Ref: TM-T4408
2mg35.00€5mg52.00€10mg70.00€25mg110.00€50mg177.00€100mg283.00€200mg426.00€1mL*10mM (DMSO)57.00€Methyl oleanonate
CAS:3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.Formula:C31H48O3Purity:98.99%Color and Shape:SolidMolecular weight:468.71Gypenoside XLIX
CAS:Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry conditionFormula:C52H86O21Purity:97.05% - 99.78%Color and Shape:SolidMolecular weight:1047.23NPC 15199
CAS:NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.
Formula:C21H23NO4Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:353.41AMG131
CAS:AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used forFormula:C21H12Cl4N2O3SPurity:99.37%Color and Shape:SolidMolecular weight:514.21MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formula:C27H34ClNO2SPurity:99.23% - 99.84%Color and Shape:SolidMolecular weight:472.08Ref: TM-T6893
1mg35.00€5mg70.00€10mg111.00€25mg216.00€50mg354.00€100mg540.00€200mg772.00€1mL*10mM (DMSO)72.00€BMS-687453
CAS:BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgammaFormula:C22H21ClN2O6Purity:99.4%Color and Shape:SolidMolecular weight:444.86Ref: TM-T5532
1mg44.00€2mg57.00€5mg93.00€10mg137.00€25mg268.00€50mg409.00€100mg620.00€1mL*10mM (DMSO)92.00€Oroxin A
CAS:Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.Formula:C21H20O10Purity:98.05% - 99.74%Color and Shape:SolidMolecular weight:432.38Ref: TM-T5S0788
1mg43.00€5mg87.00€10mg135.00€25mg221.00€50mg349.00€100mg507.00€200mg720.00€1mL*10mM (DMSO)95.00€G3335 Acetate
G3335 Acetate was discovered to be a novel PPARgamma antagonist.Formula:C18H23N3O7Purity:99.75%Color and Shape:SolidMolecular weight:393.39Ref: TM-T21598L
5mg55.00€10mg82.00€25mg126.00€50mg182.00€100mg273.00€200mg409.00€500mg677.00€1mL*10mM (DMSO)79.00€LJ570
CAS:LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Formula:C27H22O3Purity:99.64%Color and Shape:SolidMolecular weight:394.46Ref: TM-T8374
1mg138.00€2mg202.00€5mg311.00€10mg445.00€25mg680.00€50mg888.00€100mg1,234.00€500mg2,475.00€1mL*10mM (DMSO)334.00€Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Formula:C13H14Cl2O3Purity:99.63% - >99.99%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:289.15L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Formula:C22H26O7Purity:97.97%Color and Shape:SolidMolecular weight:402.44GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Formula:C19H18N2O5S2Purity:99.26% - ≥95%Color and Shape:SolidMolecular weight:418.49Ref: TM-T2674
2mg44.00€5mg65.00€10mg99.00€25mg175.00€50mg349.00€100mg520.00€500mg1,134.00€1mL*10mM (DMSO)65.00€OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formula:C44H70O16Purity:99.46% - ≥95%Color and Shape:SolidMolecular weight:855.02XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formula:C24H27N7O2Purity:98.05% - 99.89%Color and Shape:SolidMolecular weight:445.52Ref: TM-T3709
2mg44.00€5mg70.00€10mg98.00€25mg178.00€50mg290.00€100mg480.00€500mg1,161.00€1mL*10mM (DMSO)84.00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.50XMD16-5
CAS:XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Formula:C23H24N6O2Purity:98.89% - 99.98%Color and Shape:SolidMolecular weight:416.48Ref: TM-T3710
1mg42.00€2mg52.00€5mg95.00€10mg137.00€25mg213.00€50mg394.00€100mg583.00€500mg1,243.00€1mL*10mM (DMSO)95.00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:SolidMolecular weight:682.75(E/Z)-Elafibranor
CAS:GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.Formula:C22H24O4SPurity:98.36%Color and Shape:SolidMolecular weight:384.49Ref: TM-T8699
2mg35.00€5mg52.00€10mg66.00€25mg104.00€50mg167.00€100mg259.00€200mg388.00€1mL*10mM (DMSO)54.00€Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg55.00€5mg92.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg832.00€1mL*10mM (DMSO)105.00€Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Formula:C31H20O10Purity:97% - 99.69%Color and Shape:SolidMolecular weight:552.48Ref: TM-T4S2128
1mg44.00€2mg66.00€5mg137.00€10mg236.00€25mg403.00€50mg582.00€100mg800.00€1mL*10mM (DMSO)177.00€Choline Fenofibrate
CAS:Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic
Formula:C22H28ClNO5Purity:98.82%Color and Shape:SolidMolecular weight:421.91Pirinixic Acid
CAS:Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Formula:C14H14ClN3O2SPurity:98.27% - 99.92%Color and Shape:SolidMolecular weight:323.8Ref: TM-T2269
1g350.00€10mg48.00€25mg64.00€50mg79.00€100mg105.00€200mg148.00€500mg236.00€1mL*10mM (DMSO)47.00€Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).
Formula:C30H29N3O4Purity:98.1% - 98.21%Color and Shape:SolidMolecular weight:495.57GSK3787
CAS:GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.Formula:C15H12ClF3N2O3SPurity:98% - 99.56%Color and Shape:SolidMolecular weight:392.78Ref: TM-T1941
5mg55.00€10mg87.00€25mg173.00€50mg309.00€100mg520.00€500mg1,111.00€1mL*10mM (DMSO)55.00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Formula:C25H27F3N2O3Purity:97.77%Color and Shape:SolidMolecular weight:460.49Ref: TM-T39516
1mg114.00€5mg260.00€10mg389.00€25mg703.00€50mg1,054.00€100mg1,468.00€1mL*10mM (DMSO)264.00€
