Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(644 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,008 products)
- BACE(37 products)
- Beta Amyloid(227 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(60 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(326 products)
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Found 5478 products of "Neuroscience"
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Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.Formula:C23H25F2NO4Color and Shape:SolidMolecular weight:417.45AChE-IN-22
AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.Formula:C21H20N4O5SColor and Shape:SolidMolecular weight:440.47(E)-CHBO4
CAS:(E)-CHBO4 is an MAO-B inhibitor with an IC50 value of 0.023 μM, making it a potential candidate for research into Parkinson's disease treatment.Formula:C15H10BrFOColor and Shape:SolidMolecular weight:305.1425-HT1A antagonist 1
Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.Formula:C23H29ClN6O2Color and Shape:SolidMolecular weight:456.97Pomaglumetad methionil
CAS:Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.Formula:C12H20N2O8S2Purity:98%Color and Shape:SolidMolecular weight:384.43Rodatristat
CAS:Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).Formula:C27H27ClF3N5O3Purity:98%Color and Shape:SolidMolecular weight:561.98CaMKIIα-IN-1
CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.Formula:C14H11ClO4Color and Shape:SolidMolecular weight:278.69β-CCM
CAS:β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and convulsant effects. It enhances emotional reactivity and reduces interference sensitivity in spatial working memory tasks. β-CCM is applicable in research related to anxiety disorders.Formula:C13H10N2O2Color and Shape:SolidMolecular weight:226.231NY0116
CAS:NY0116 is an agonist of the neuromedin U receptor 2 (NMUR2), exhibiting EC50 values of 27.76 μM for hNMUR1 and 13.61 μM for hNMUR2. In NMUR2 stably expressing HEK293 cells, NY0116 reduces cAMP levels while enhancing calcium signaling [1].Formula:C22H23N3OColor and Shape:SolidMolecular weight:345.44BMS-901715
CAS:BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).Formula:C22H28N10OPurity:98%Color and Shape:SolidMolecular weight:448.52AChE-IN-10
AChE-IN-10 (24r) inhibits AChE (IC50=2.4 nM), reducing amyloid buildup, tau phosphorylation, and promotes neuron health.Formula:C23H27F2NO4SColor and Shape:SolidMolecular weight:451.53HW161023
CAS:HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.Formula:C20H24F2N4OColor and Shape:SolidMolecular weight:374.428UB 165
CAS:Subtype-selective nicotinic agonistFormula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.72HDAC6-IN-9
CAS:HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.Formula:C19H16N2O3Purity:98.84%Color and Shape:SolidMolecular weight:320.345-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Formula:C21H26N6SColor and Shape:SolidMolecular weight:394.54K027
K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.Formula:C15H18Br2N4O2Color and Shape:SolidMolecular weight:446.14LRRK2-IN-2
CAS:LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.Formula:C23H23Cl2F3N6O2Color and Shape:SolidMolecular weight:543.37SGE-516
CAS:SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.Formula:C23H35N3O2Purity:98%Color and Shape:SolidMolecular weight:385.54Alixorexton
CAS:Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.Formula:C21H30N2O5SColor and Shape:SolidMolecular weight:422.538Aβ aggregation-IN-1
CAS:Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.Formula:C9H8BF3O2Color and Shape:SolidMolecular weight:215.965PTCA
CAS:PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.Formula:C10H5Cl2NO2SColor and Shape:SolidMolecular weight:274.123LRRK2-IN-14
CAS:LRRK2-IN-14 (Compound 8), an orally active inhibitor of LRRK2, exhibits an IC 50 of 6.3 nM against LRRK2(G2019S) cell activity and demonstrates inhibitory effects on hERG with an IC 50 of 22 μM. Additionally, LRRK2-IN-14 is permeable to the blood-brain barrier [1].Formula:C17H18F3N5O2Color and Shape:SolidMolecular weight:381.35AChE-IN-11
AChE-IN-11 aids Alzheimer's research, has neuroprotection/antioxidant properties (ORAC=2.5), and acts on AChE, MAO-B, BACE1 with IC50 values of 7.9-9.9 μM.Formula:C18H28N2O4Color and Shape:SolidMolecular weight:336.43(+)-Sparteine sulfate pentahydrate
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.Formula:C15H38N2O9SColor and Shape:SolidMolecular weight:422.54nAChR antagonist 1
CAS:Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.Formula:C19H22N4O2Color and Shape:SolidMolecular weight:338.4(S)-YNT-3708
CAS:(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.Formula:C35H36N4O6SColor and Shape:SolidMolecular weight:640.749Terguride
CAS:Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.Formula:C20H28N4OColor and Shape:SolidMolecular weight:340.46AAK1-IN-2 TFA
AAK1-IN-2 TFA (compound (S)-31) is a selective and potent AAK1 inhibitor (IC50: 5.8 nM) that can cross the blood-brain barrier.Formula:C24H22F6N4O4Color and Shape:SolidMolecular weight:544.45(R,R)-LRRK2-IN-7
CAS:(R,R)-LRRK2-IN-7 is an isomer of LRRK2-IN-7, a potent and selective LRRK2 kinase inhibitor with CNS penetrance. It exhibits an IC50 of 0.9 nM and demonstrates over 1000-fold selectivity compared to other kinases, ion channels, and CYP enzymes.Formula:C24H26N6OMolecular weight:414.50BChE-IN-3
BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.Formula:C26H41N3O2Color and Shape:SolidMolecular weight:427.62Zanapezil fumarate
CAS:Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.Formula:C29H36N2O5Color and Shape:SolidMolecular weight:492.61CEase-IN-1
CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.Formula:C13H15F3N2O2Color and Shape:SolidMolecular weight:288.27Geissoschizoline
CAS:Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42Avitriptan
CAS:Avitriptan is a 5-HT1B/1D receptor agonist with pKi values of 7.44 for 5-HT1Brat, 7.68 for 5-HT1Bhuman, and 8.36 for 5-HT1Dhuman. It can induce contraction in isolated coronary arteries and is used for the treatment of migraines.Formula:C22H30N6O3SMolecular weight:458.577SB 243213 dihydrochloride
CAS:SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 forFormula:C22H21Cl2F3N4O2Purity:98%Color and Shape:SolidMolecular weight:501.33MAO-A inhibitor 3
CAS:MAO-A inhibitor3 (Compound 360) is an MAO-A inhibitor with an IC50 greater than 100 μM. It is utilized in the investigation of neurological disorders.Formula:C11H8O5Color and Shape:SolidMolecular weight:220.178ChE/Aβ1-42-IN-1
ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.Formula:C19H24N2O3Color and Shape:SolidMolecular weight:328.41SRI-31255
CAS:SRI-31255 is an orally active LRRK2 inhibitor, with IC50 values of 520 nM for human wild-type (WT) and 427 nM for the G2019S mutant. It inhibits kinase activity by binding to the ATP-binding pocket of LRRK2, providing neuroprotective effects. SRI-31255 serves as a lead compound for developing LRRK2-targeted therapies for Parkinson’s disease research.Formula:C15H14N4Color and Shape:SolidMolecular weight:250.30LRRK2-IN-16
CAS:LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.Formula:C18H19N5OSColor and Shape:SolidMolecular weight:353.441hAChE-IN-10
CAS:hAChE-IN-10 (Compound ET11) is an inhibitor of human acetylcholinesterase (AChE) with an IC50 of 6.34 nM. This compound is capable of scavenging free radicals and exhibits antioxidant activity. Additionally, hAChE-IN-10 demonstrates metal-chelating properties, inhibiting Cu2+-induced Aβ1-42 aggregation, reducing amyloid plaque formation, and offering neuroprotective effects. It also ameliorates cognitive impairment in mice induced by Scopolamine.Formula:C25H24ClFN6O2Color and Shape:SolidMolecular weight:494.948BF-168
CAS:BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).Formula:C18H17FN2O2Color and Shape:SolidMolecular weight:312.345-IAI hydrochloride
CAS:5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.Formula:C9H11ClINColor and Shape:SolidMolecular weight:295.548AChE/BACE1/GSK3β-IN-1
AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.Formula:C26H27FN2O4Color and Shape:SolidMolecular weight:450.5LK-732
CAS:LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.Formula:C25H29N5O3SColor and Shape:SolidMolecular weight:479.59AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formula:C14H21BrN2OColor and Shape:SolidMolecular weight:313.23AAZ-A 154 benzoate
CAS:AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44Aβ42-IN-1
CAS:Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C29H27ClN4O2Purity:98%Color and Shape:SolidMolecular weight:499AAZ-A 154 hydrochloride
CAS:AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formula:C14H21ClN2OColor and Shape:SolidMolecular weight:268.78BPN-15606 besylate
BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).Formula:C29H29FN6O4SColor and Shape:SolidMolecular weight:576.64DSP-1053 benzenesulfonate
CAS:DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.Formula:C32H38BrNO7SColor and Shape:SolidMolecular weight:660.62(R)-(-)-Pirlindole mesylate
CAS:(R)-(–)-Pirlindole acts as a monoamine oxidase A (MAO-A) inhibitor with an IC50 value of 0.43 µM, exhibiting selectivity for MAO-A compared to MAO-B. When administered at 50 mg/kg, it reduces immobility time in the forced swim test in mice and, at 25 mg/kg, inhibits reserpine-induced palpebral ptosis in mice.Formula:C16H22N2O3SColor and Shape:SolidMolecular weight:322.42Anti-Aβ agent 1A
Anti-Aβ agent 1A is a potent anti-amyloid-β agent.Formula:C35H49NO4Color and Shape:SolidMolecular weight:547.77Rocavorexant
CAS:Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.Formula:C18H19F3N8OColor and Shape:SolidMolecular weight:420.392AAZ-A 154
CAS:AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32Lu 26-046
CAS:Lu 26-046 is a muscarinic receptor agonist.Formula:C10H12N2OSColor and Shape:SolidMolecular weight:208.28VU6005806
CAS:VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.Formula:C17H16F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:439.41Glutaminyl Cyclase Inhibitor 3
CAS:Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formula:C24H32N6O2SPurity:98%Color and Shape:SolidMolecular weight:468.61BACE1-IN-2
CAS:BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).Formula:C19H15F4N5O2Purity:98%Color and Shape:SolidMolecular weight:421.35D3/5-HT receptor modulator-1
CAS:D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.Formula:C24H29N3O2Color and Shape:SolidMolecular weight:391.506LB-102
CAS:LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.Formula:C18H29N3O4SColor and Shape:SolidMolecular weight:383.5125B-NBOH hydrochloride
CAS:25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.Formula:C17H21BrClNO3Color and Shape:SolidMolecular weight:402.711AChE-IN-84
CAS:AChE-IN-84 (compound 21) is an inhibitor of AChE.Formula:C6H15Br2NColor and Shape:SolidMolecular weight:260.998MAO-B-IN-42
CAS:MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.Formula:C19H12FNO2Color and Shape:SolidMolecular weight:305.302LY2794193
CAS:LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.Formula:C16H18N2O6Purity:98.15%Color and Shape:SolidMolecular weight:334.32DAPM
CAS:DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.Formula:C20H20F2N2O4Purity:99.76%Color and Shape:SolidMolecular weight:390.38LY367385 hydrochloride
CAS:LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.Formula:C10H12ClNO4Color and Shape:SolidMolecular weight:245.66(-)-5-HT2C agonist-3
CAS:Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.Formula:C19H23ClFNO2Color and Shape:SolidMolecular weight:351.84BChE-IN-5
BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.Formula:C30H42N4OColor and Shape:SolidMolecular weight:474.6825C-NBF hydrochloride
CAS:25C-NBF hydrochloride is an agonist of 5-HT receptors, specifically activating 5-HT2A and 5-HT2C receptors, with an EC50 of approximately 0.3 μM.Formula:C17H20Cl2FNO2Molecular weight:360.251RO-1-5237
CAS:RO-1-5237, a cholinergic compound and a metabolic product of Pyridostigmine Bromide, is utilized in research for myasthenia gravis.Formula:C6H8BrNOColor and Shape:SolidMolecular weight:190.04SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purity:98.99% - 99.96%Color and Shape:SolidMolecular weight:557.08LY2979165
CAS:LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.Formula:C13H22N6O6SPurity:98.41%Color and Shape:SolidMolecular weight:390.42Umibecestat
CAS:Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.Formula:C19H15ClF7N5O2Purity:99.88%Color and Shape:SolidMolecular weight:513.8Ref: TM-T13253
1mg163.00€5mg334.00€10mg485.00€25mg807.00€50mg1,099.00€100mg1,485.00€1mL*10mM (DMSO)376.00€NB-360
CAS:NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.Formula:C21H19F4N5O2Purity:99.72%Color and Shape:SolidMolecular weight:449.4Ref: TM-T12188
1mg104.00€5mg215.00€10mg318.00€25mg510.00€50mg692.00€100mg888.00€500mg1,783.00€1mL*10mM (DMSO)235.00€BMS 299897
CAS:BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.Formula:C24H21ClF3NO4SPurity:99.82%Color and Shape:SolidMolecular weight:511.94AChE/BChE-IN-10
CAS:AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.
Formula:C26H30N2O2Purity:99.55% - 99.88%Color and Shape:SoildMolecular weight:402.53Iclepertin
CAS:Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.Formula:C20H18F6N2O5SPurity:98.89% - 98.93%Color and Shape:SolidMolecular weight:512.42Ref: TM-T37089
1mg90.00€2mg114.00€5mg160.00€10mg212.00€25mg349.00€50mg522.00€100mg783.00€200mg1,054.00€1mL*10mM (DMSO)173.00€AChE-IN-26
CAS:AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).
Formula:C21H21BrN2O3Purity:99.24% - 99.85%Color and Shape:SoildMolecular weight:429.314-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS:Formula:C5H5N5OPurity:>93.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystallineMolecular weight:151.13YM-298198 hydrochloride
CAS:mGlu1 receptor antagonistFormula:C18H23ClN4OSPurity:98%Color and Shape:SolidMolecular weight:378.919Xanthocillin X permethyl ether
CAS:Xanthocillin X permethyl ether, a natural product extracted from fungal sources, exhibits Aβ-42 lowering activity.Formula:C20H16N2O2Purity:98%Color and Shape:SolidMolecular weight:316.35BF 227
CAS:BF 227 is a candidate for an amyloid imaging probe for PET [Ki: 4.3 nM for Aβ1-42 fibrils].Formula:C16H16FN3O2SColor and Shape:SolidMolecular weight:333.38Eglumegad
CAS:Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).Formula:C8H11NO4Color and Shape:SolidMolecular weight:185.18Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formula:C15H21N3O2S3Color and Shape:White SolidMolecular weight:371.54Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:339.84SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formula:C18H22Cl3N3O4SPurity:98%Color and Shape:SolidMolecular weight:482.81(-)-Bicuculline methobromide
CAS:(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .Formula:C21H20BrNO6Color and Shape:WhiteMolecular weight:462.297-Desmethyl-agomelatine
CAS:7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formula:C14H15NO2Color and Shape:SolidMolecular weight:229.27(RS)-APICA
CAS:group II metabotropic glutamate receptor antagonistFormula:C10H12NO5PColor and Shape:SolidMolecular weight:257.182-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-onehydrochloride
CAS:Formula:C13H19Cl2NOPurity:98%Color and Shape:SolidMolecular weight:276.2021Rat NT3(Neurotrophin 3) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NT3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NT3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat NT3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat NT3 in the samples is then determined by comparing the OD of the samples to the standard curve.
3-(3,4-DIHYDROXYPHENYL-2,5,6-D3)-L-ALANINE
CAS:Formula:C9H8D3NO4Purity:98%Color and Shape:SolidMolecular weight:200.2064(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Formula:C24H31FO6Purity:99%Color and Shape:SolidMolecular weight:434.4977Ref: IN-DA0039HQ
Discontinued product3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-
CAS:Formula:C13H14N2OPurity:98%Color and Shape:SolidMolecular weight:214.2631Ref: IN-DA003TYN
Discontinued product9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Formula:C22H29FO5Purity:99%Color and Shape:SolidMolecular weight:392.4611
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