Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,022 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
Show 12 more subcategories
Found 5562 products of "Neuroscience"
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MFZ 10-7
CAS:MFZ 10-7 is anegative allosteric modulator of the mGluR5.Formula:C15H9FN2Purity:99.80%Color and Shape:SolidMolecular weight:236.24LY320954
CAS:LY320954 is an antagonist of 5-HT2A receptor.Formula:C21H26N4O3Purity:98%Color and Shape:SolidMolecular weight:382.46(S)-Renzapride
(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.Formula:C16H22ClN3O2Color and Shape:SolidMolecular weight:323.82GR-127935
CAS:GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.Formula:C29H31N5O3Color and Shape:SolidMolecular weight:497.59AMG-8718
CAS:AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.Formula:C25H19FN4O3Color and Shape:SolidMolecular weight:442.44CGP 55845 hydrochloride
CAS:CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Formula:C18H23Cl3NO3PColor and Shape:SolidMolecular weight:438.71L-772,405
CAS:L-772,405 is a highly selective agonists of h5-HT(1D) receptor.Formula:C26H31FN6OPurity:98%Color and Shape:SolidMolecular weight:462.56rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formula:C18H21FN4O2Purity:99.44%Color and Shape:SolidMolecular weight:344.38CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Formula:C18H22Cl2NO3PColor and Shape:SolidMolecular weight:402.25LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Formula:C28H38N2O2Color and Shape:SolidMolecular weight:434.61ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Formula:C9H15ClN2OColor and Shape:SolidMolecular weight:202.68Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Formula:C20H22ClF2N3OColor and Shape:SolidMolecular weight:393.86BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Formula:C18H14F3N5O2Purity:98%Color and Shape:SolidMolecular weight:389.33JM-1232
CAS:JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.Formula:C24H27N3O2Color and Shape:SolidMolecular weight:389.49Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Formula:C17H23NO3Color and Shape:SolidMolecular weight:289.37NO-711ME
CAS:NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Formula:C22H24N2O3Purity:99.54%Color and Shape:SolidMolecular weight:364.44Ref: TM-T24540
1mg64.00€5mg129.00€1mL*10mM (DMSO)138.00€10mg188.00€25mg299.00€50mg427.00€100mg575.00€200mg767.00€BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formula:C26H26F4N4O3Color and Shape:SolidMolecular weight:518.5Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Formula:C18H23FN2O2Purity:98%Color and Shape:SolidMolecular weight:318.39QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Formula:C19H13NO3Color and Shape:SolidMolecular weight:303.31Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purity:99.35% - 99.89%Color and Shape:SolidMolecular weight:359.47BACE1-IN-10
CAS:BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].Formula:C33H49N5O8SPurity:98%Color and Shape:SolidMolecular weight:675.84Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Formula:C19H24BrNO5S2Purity:98.44% - 99.41%Color and Shape:SolidMolecular weight:490.43Hydroxy Varenicline
CAS:Hydroxy varenicline, a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline, functions within the biochemical pathway by interacting with nAChR sites.Formula:C13H13N3OColor and Shape:SolidMolecular weight:227.267CGP36216 hydrochloride
CAS:CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Formula:C5H15ClNO2PColor and Shape:SolidMolecular weight:187.6Butriptyline
CAS:Butriptyline (Butriptylene), a tricyclic antidepressant, is effective when administered orally [1].Formula:C21H27NColor and Shape:SolidMolecular weight:293.45GABA-IN-2
CAS:GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1Formula:C12H4Cl2F6N4SeColor and Shape:SolidMolecular weight:468.041-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Formula:C9H14O4Color and Shape:SolidMolecular weight:186.207CGP 54626 hydrochloride
CAS:CGP 54626 hydrochloride is a GABAB receptor antagonist.Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76Afizagabar
CAS:Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.Formula:C19H12FN3O2SColor and Shape:SolidMolecular weight:365.38VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Formula:C18H15FN2OPurity:99.56%Color and Shape:SolidMolecular weight:294.32L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Formula:C4H10NO5PPurity:98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:183.1AChE-IN-44
CAS:AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].Formula:C31H38ClN3OS2Color and Shape:SolidMolecular weight:568.24TPA 023
CAS:TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).Formula:C20H22FN7OPurity:99.75%Color and Shape:SolidMolecular weight:395.43L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Formula:C11H15N3OColor and Shape:SolidMolecular weight:205.26FGIN-1-27
CAS:FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6AChE-IN-31
CAS:AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].Formula:C27H44Na2O9S2Color and Shape:SolidMolecular weight:622.74mGAT3/4-IN-2
CAS:mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.Formula:C26H32ClN3OS2Color and Shape:SolidMolecular weight:502.13QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Formula:C29H25N4NaO3S2Color and Shape:SolidMolecular weight:564.65MAO-B-IN-13
CAS:MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).Formula:C18H19NO3Color and Shape:SolidMolecular weight:297.35Diproqualone
CAS:Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].Formula:C12H14N2O3Color and Shape:SolidMolecular weight:234.255LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Formula:C13H14ClN3O2SPurity:98.78%Color and Shape:SolidMolecular weight:311.79Yhhu-3792 hydrochloride
CAS:Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].Formula:C24H25ClN4O2Color and Shape:SolidMolecular weight:436.93Abaperidone
CAS:Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Formula:C25H25FN2O5Purity:99.77%Color and Shape:SolidMolecular weight:452.47β-Secretase Inhibitor IV
CAS:β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).Formula:C31H38N4O5SPurity:98%Color and Shape:SolidMolecular weight:578.72MK-8768
CAS:MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized byFormula:C21H22F3N5O2Color and Shape:SolidMolecular weight:433.43VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Formula:C10H11N3S2Color and Shape:SolidMolecular weight:237.34AAK1-IN-3
CAS:AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.Formula:C20H20N4Color and Shape:SolidMolecular weight:316.45-HT3 antagonist 1
CAS:5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Formula:C22H27N5OPurity:98%Color and Shape:SolidMolecular weight:377.48GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Formula:C23H18N4O2Color and Shape:SolidMolecular weight:382.41
