Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(940 products)
- ACK(1 products)
- AChR(574 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,939 products)
- BACE(36 products)
- Beta Amyloid(204 products)
- CaMK(68 products)
- Cyclooxygenase (COX) Inhibitors(562 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(296 products)
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Found 5400 products of "Neuroscience"
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SB-224289 hydrochloride
CAS:<p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>Formula:C32H33ClN4O3Purity:97.82% - 98.99%Color and Shape:SolidMolecular weight:557.08AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Formula:C26H30N2O2Purity:99.55% - 99.88%Color and Shape:SoildMolecular weight:402.53AChE-IN-26
CAS:<p>AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).</p>Formula:C21H21BrN2O3Purity:99.24% - 99.85%Color and Shape:SoildMolecular weight:429.31LY2979165
CAS:<p>LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.</p>Formula:C13H22N6O6SPurity:98.41%Color and Shape:SolidMolecular weight:390.42NB-360
CAS:<p>NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.</p>Formula:C21H19F4N5O2Purity:99.72%Color and Shape:SolidMolecular weight:449.4BDZ-g
CAS:<p>BDZ-g: potent, selective AMPA receptor antagonist; useful for researching neurological disorders.</p>Formula:C21H21N5O2SPurity:99.97%Color and Shape:SolidMolecular weight:407.49BMS 299897
CAS:<p>BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.</p>Formula:C24H21ClF3NO4SPurity:99.82%Color and Shape:SolidMolecular weight:511.94Iclepertin
CAS:<p>Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.</p>Formula:C20H18F6N2O5SPurity:98.89% - 98.93%Color and Shape:SolidMolecular weight:512.424-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS:Formula:C5H5N5OPurity:>93.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystallineMolecular weight:151.13YM-298198 hydrochloride
CAS:<p>mGlu1 receptor antagonist</p>Formula:C18H23ClN4OSPurity:98%Color and Shape:SolidMolecular weight:378.919(-)-Bicuculline methobromide
CAS:<p>(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .</p>Formula:C21H20BrNO6Color and Shape:WhiteMolecular weight:462.29(RS)-APICA
CAS:<p>group II metabotropic glutamate receptor antagonist</p>Formula:C10H12NO5PColor and Shape:SolidMolecular weight:257.18BF 227
CAS:<p>BF 227 is a candidate for an amyloid imaging probe for PET [Ki: 4.3 nM for Aβ1-42 fibrils].</p>Formula:C16H16FN3O2SColor and Shape:SolidMolecular weight:333.38Arotinolol
CAS:<p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>Formula:C15H21N3O2S3Color and Shape:White SolidMolecular weight:371.547-Desmethyl-agomelatine
CAS:<p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>Formula:C14H15NO2Color and Shape:SolidMolecular weight:229.27SB-399885 hydrochloride
CAS:<p>SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.</p>Formula:C18H22Cl3N3O4SPurity:98%Color and Shape:SolidMolecular weight:482.81MG 624
CAS:<p>neuronal α7 nAChR antagonist</p>Formula:C22H30INOColor and Shape:SolidMolecular weight:451.38Eglumegad
CAS:<p>Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).</p>Formula:C8H11NO4Color and Shape:SolidMolecular weight:185.18Xanthocillin X permethyl ether
CAS:<p>Xanthocillin X permethyl ether, a natural product extracted from fungal sources, exhibits Aβ-42 lowering activity.</p>Formula:C20H16N2O2Purity:98%Color and Shape:SolidMolecular weight:316.35Pumosetrag Hydrochloride
CAS:<p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>Formula:C15H18ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:339.843-(3,4-DIHYDROXYPHENYL-2,5,6-D3)-L-ALANINE
CAS:Formula:C9H8D3NO4Purity:98%Color and Shape:SolidMolecular weight:200.2064Phosphonic acid, P-methyl-, bis(1-methylethyl) ester
CAS:Formula:C7H17O3PPurity:98%Color and Shape:LiquidMolecular weight:180.1818(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Formula:C24H31FO6Purity:99%Color and Shape:SolidMolecular weight:434.4977Ref: IN-DA0039HQ
Discontinued product1,2-Benzisoxazole-4,5,6,7-d4-3-methanesulfonamide
CAS:Formula:C8H4D4N2O3SPurity:CP：95%，95 atom % DColor and Shape:SolidMolecular weight:216.25043H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-
CAS:Formula:C13H14N2OPurity:98%Color and Shape:SolidMolecular weight:214.26319a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Formula:C22H29FO5Purity:99%Color and Shape:SolidMolecular weight:392.4611Ref: IN-DA003TYN
Discontinued product1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROXPYRIDINE
CAS:Controlled ProductFormula:C12H15NPurity:95%Color and Shape:SolidMolecular weight:173.254211β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Formula:C21H28O5Purity:98%Color and Shape:SolidMolecular weight:360.44402-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-onehydrochloride
CAS:Formula:C13H19Cl2NOPurity:98%Color and Shape:SolidMolecular weight:276.202111β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Formula:C21H30O5Purity:98%Color and Shape:SolidMolecular weight:362.4599Ref: IN-DA003AAY
Discontinued product(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione
CAS:Formula:C20H24O2Purity:99%Color and Shape:SolidMolecular weight:296.4034Ebeiedinone
CAS:<p>Ebeiedinone, a steroidal alkaloid derived from Fritillaria species, effectively inhibits the activity of human whole blood cholinesterase (ChE) at a concentration of 0.1 mM, resulting in a significant inhibitory effect of 69.0%.</p>Formula:C27H43NO2Color and Shape:SolidMolecular weight:413.64Physostigmine
CAS:<p>Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE).</p>Formula:C15H21N3O2Purity:98%Color and Shape:Orthorhombic Sphenoidal Prisms Or Clusters Of Leaflets From Ether Or Benzene (Anticholinesterase) Agent And As A Veterinary Medication (Epa 1998)Molecular weight:275.35VU6000918
CAS:<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Formula:C18H17F2N5OSColor and Shape:SolidMolecular weight:389.42BRL 15572
CAS:<p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>Formula:C25H27ClN2OColor and Shape:SolidMolecular weight:406.95Sarizotan
CAS:<p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>Formula:C22H21FN2OColor and Shape:SolidMolecular weight:348.421VU0080241
CAS:<p>VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4).</p>Formula:C19H23N5Color and Shape:SolidMolecular weight:321.42Eglumegad hydrochloride
<p>Eglumegad (LY354740) hydrochloride is a potent, selective agonist for group II (mGlu2/3) receptors, showing IC50 values of 5 nM for mGlu2 and 24 nM for mGlu3 receptors in transfected human cells. This compound provides neuroprotection against NMDA-induced toxicity and exhibits anxiolytic- and antipsychotic-like properties [1].</p>Formula:C8H12ClNO4Color and Shape:SolidMolecular weight:221.642-AEMP TFA
CAS:<p>2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.</p>Formula:C3H10NO3PPurity:98%Color and Shape:SolidMolecular weight:139.091Calmodulin antagonist-1
CAS:<p>Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.</p>Formula:C14H18Cl2N2O2SColor and Shape:SolidMolecular weight:349.27Desmethyl cariprazine
CAS:<p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>Formula:C20H30Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:413.38Alfadolone acetate
CAS:<p>Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.</p>Formula:C23H34O5Color and Shape:SolidMolecular weight:390.513-Methylglutaconic acid
CAS:<p>3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].</p>Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:144.13(S)-Rasagiline
CAS:<p>(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.</p>Formula:C12H13NColor and Shape:SolidMolecular weight:171.24Ref: TM-T13252
Discontinued product(Rac)-Rotigotine hydrochloride
CAS:<p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>Formula:C19H26ClNOSColor and Shape:SolidMolecular weight:351.93
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