Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(942 products)
- ACK(1 products)
- AChR(576 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,949 products)
- BACE(36 products)
- Beta Amyloid(205 products)
- CaMK(69 products)
- Cyclooxygenase (COX) Inhibitors(565 products)
- Dopamine Receptor(410 products)
- GABA Receptor(337 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(359 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(26 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
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Found 5389 products of "Neuroscience"
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Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.41Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:<p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>Formula:C22H27Cl3F3N3SColor and Shape:SolidMolecular weight:528.89DCCCyb
CAS:<p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>Formula:C22H29Cl2NO3SPurity:98%Color and Shape:SolidMolecular weight:458.44[D-Trp7,9,10]-Substance P
CAS:<p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>Formula:C79H105N21O13SPurity:98%Color and Shape:SolidMolecular weight:1588.89Tampramine
CAS:<p>Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.</p>Formula:C23H24N4Purity:99.87%Color and Shape:SolidMolecular weight:356.46DISC-0974
<p>DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.</p>Color and Shape:LiquidMolecular weight:145.5kDahAChE-IN-5
<p>hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with</p>Purity:98%Color and Shape:Odour SolidLupanine hydrochloride
CAS:<p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>Formula:C15H25ClN2OColor and Shape:SolidMolecular weight:284.83β-Amyloid (35-42)
CAS:<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formula:C33H60N8O9SPurity:98%Color and Shape:SolidMolecular weight:744.94Lesogaberan napadisylate
CAS:<p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>Formula:C13H17FNO5PSColor and Shape:SolidMolecular weight:349.31(+)-Coclaurine hydrochloride
CAS:<p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>Formula:C17H20ClNO3Purity:98%Color and Shape:SolidMolecular weight:321.8Muscarine
CAS:<p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Formula:C9H20NO2Purity:98%Color and Shape:SolidMolecular weight:174.26FGIN-1-43
CAS:<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Formula:C28H36Cl2N2OPurity:99.57%Color and Shape:SolidMolecular weight:487.5Flufiprole
CAS:<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Formula:C16H10Cl2F6N4OSColor and Shape:SolidMolecular weight:491.24Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formula:C72H105N19O20Purity:98%Color and Shape:SolidMolecular weight:1556.72Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formula:C18H22N2SPurity:98%Color and Shape:SolidMolecular weight:306.5TB-11
CAS:<p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>Formula:C52H78N8O12Color and Shape:SolidMolecular weight:1007.22RBPJ Inhibitor-1
CAS:<p>RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell</p>Formula:C17H14FN3O2Purity:99.58%Color and Shape:SoildMolecular weight:311.31NMDAR antagonist 2
<p>NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.</p>Formula:C17H20ClNOColor and Shape:SolidMolecular weight:289.8PD25
<p>PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.</p>Formula:C25H24N2O4Color and Shape:SolidMolecular weight:416.47Brexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formula:C25H19D8N3O3SPurity:98%Color and Shape:SolidMolecular weight:457.61β-Amyloid Protein Precursor 770 (135-155)
CAS:<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formula:C116H172N35O31S2Purity:98%Color and Shape:SolidMolecular weight:2617.96(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Formula:C10H20ClNO2Purity:99.26% - >99.99%Color and Shape:SoildMolecular weight:221.72Imagabalin
CAS:<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Formula:C9H19NO2Color and Shape:SolidMolecular weight:173.25Proadrenomedullin (1-20), human
CAS:<p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>Formula:C112H178N36O27Purity:98%Color and Shape:SolidMolecular weight:2460.84BIMU 8
CAS:<p>BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.</p>Formula:C19H27ClN4O2Purity:99.87%Color and Shape:SolidMolecular weight:378.9EB-42486
CAS:EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Formula:C22H22N8OPurity:99.53%Color and Shape:SolidMolecular weight:414.46hAChE-IN-6
<p>hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM.</p>Color and Shape:Odour SolidCytidine 5′-diphosphoethanolamine
CAS:<p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>Formula:C11H20N4O11P2Color and Shape:SolidMolecular weight:446.24Fentonium bromide
CAS:<p>Fentonium bromide is a biochemical.</p>Formula:C31H34BrNO4Color and Shape:SolidMolecular weight:564.51(E/Z)-Sivopixant
CAS:<p>(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.</p>Formula:C25H22ClN5O5Purity:99.82%Color and Shape:SolidMolecular weight:507.93δ-secretase inhibitor 11
CAS:<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Formula:C10H12N4O2Purity:99.84%Color and Shape:SolidMolecular weight:220.23Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formula:C15H22O2Color and Shape:SolidMolecular weight:234.33Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formula:C17H19N3OColor and Shape:SolidMolecular weight:281.359Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formula:C20H21NO5Color and Shape:SolidMolecular weight:355.38Glycerophosphorylethanolamine (sodium salt)
CAS:<p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>Formula:C5H13NNaO6PColor and Shape:SolidMolecular weight:237.125-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Formula:C13H18N2OPurity:98.25%Color and Shape:SolidMolecular weight:218.29JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Color and Shape:SolidAChE-IN-86
<p>AChE-IN-86 (Compound 6f) is an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 25.33 μg/mL. This compound exerts its inhibitory effects by forming hydrogen bonds, π-π, and π-alkyl interactions with amino acid residues at the key catalytic site of AChE. AChE-IN-86 can be utilized in Alzheimer's disease research.</p>Formula:C28H27N3O6SColor and Shape:SolidMolecular weight:533.595CZC-54252 hydrochloride
CAS:<p>CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.</p>Formula:C22H26Cl2N6O4SPurity:98.21%Color and Shape:SolidMolecular weight:541.45SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Formula:C25H30ClN3O3SColor and Shape:SolidMolecular weight:488.04(Rac)-Norcisapride
CAS:<p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>Formula:C14H20ClN3O3Purity:99.32%Color and Shape:SoildMolecular weight:313.78Antidepressant agent 5
CAS:<p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>Formula:C20H25NO3Purity:99.34%Color and Shape:SoildMolecular weight:327.42MAO-IN-6
<p>MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.</p>Formula:C22H14F3NO2Color and Shape:SolidMolecular weight:381.35MIDD0301
CAS:<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42(R)-(+)-Anatabine
CAS:<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Formula:C10H12N2Purity:98%Color and Shape:SolidMolecular weight:160.22[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Formula:C120H206N44O35SPurity:98%Color and Shape:SolidMolecular weight:2857.28Biphenyl-3′,3,4,4′-tetrol
CAS:Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.Formula:C12H10O4Color and Shape:SolidMolecular weight:218.21Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45
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