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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5390 products of "Neuroscience"

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  • VA012
    Targetmol
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    VA012

    CAS:
    <p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>
    Formula:C21H19N3
    Color and Shape:Solid
    Molecular weight:313.40

    Ref: TM-T200241

  • MAO-A/SERT-IN-1
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    MAO-A/SERT-IN-1

    CAS:
    <p>MAO-A/SERT-IN-1 acts as an inhibitor for both MAO-A and the serotonin transporter (SERT). It decreases the SERT-mediated reuptake of 5-HT and demonstrates neuroprotective properties in cellular inhibition models. Additionally, this compound has shown to alleviate depressive behaviors in both zebrafish and mice.</p>
    Formula:C19H14N2O5
    Color and Shape:Solid
    Molecular weight:350.32

    Ref: TM-T200256

  • 5-HT2A/5-HT2C inverse agonist 1
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    5-HT2A/5-HT2C inverse agonist 1

    CAS:
    <p>5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.</p>
    Formula:C24H35N5O2
    Color and Shape:Solid
    Molecular weight:425.57

    Ref: TM-T200089

  • BACE1-IN-5
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    BACE1-IN-5

    CAS:
    <p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) &amp; Aβ production (IC50: 0.82 nM), enhances hERG inhibition &amp; P-gp efflux.</p>
    Formula:C18H16F5N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.41

    Ref: TM-T10453

  • Revexepride
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    Revexepride

    CAS:
    <p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>
    Formula:C21H32ClN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:425.95

    Ref: TM-T16737

  • Serotonin maleate
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    Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Formula:C14H16N2O5
    Color and Shape:Solid
    Molecular weight:292.287

    Ref: TM-T204388

  • FP0429
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    FP0429

    CAS:
    FP0429 is an agonist of mGlu4.
    Formula:C10H12N2O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:272.21

    Ref: TM-T27355

  • BRD0418
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    BRD0418

    CAS:
    <p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>
    Formula:C29H32N2O5
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:488.57

    Ref: TM-T30577

  • 2,6-Dimethoxybenzylamine hydrochloride
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    2,6-Dimethoxybenzylamine hydrochloride

    CAS:
    <p>2,6-Dimethoxybenzylamine hydrochloride (Compound 5) exhibits reversible inhibitory activity against copper amine oxidase (CAO) and inhibits benzylamine oxidase (BAO) and monoamine oxidase B (MAO B) with IC50 values of 120 μM and 190 μM, respectively.</p>
    Formula:C9H14ClNO2
    Color and Shape:Solid
    Molecular weight:203.666

    Ref: TM-T204789

  • LY367385 hydrochloride
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    LY367385 hydrochloride

    CAS:
    <p>LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.</p>
    Formula:C10H12ClNO4
    Color and Shape:Solid
    Molecular weight:245.66

    Ref: TM-T60355

  • Carlina oxide
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    Carlina oxide

    CAS:
    <p>Carlina oxide is both an AChE inhibitor and an antioxidant, effective in eliminating mosquito larvae (LC50=1.39 μg/mL). Furthermore, Carlina oxide exhibits cytotoxicity in vertebrate cells, human dermis, and HCT116 and MDA-MB231 cell lines.</p>
    Formula:C13H10O
    Color and Shape:Solid
    Molecular weight:182.22

    Ref: TM-T88796

  • AChE/BuChE-IN-3
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    AChE/BuChE-IN-3

    CAS:
    <p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>
    Formula:C30H30F3N3O6
    Color and Shape:Solid
    Molecular weight:585.57

    Ref: TM-T64137

  • Buntanetap L-Tartrate
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    Buntanetap L-Tartrate

    CAS:
    <p>Buntanetap (L-Tartrate) functions as an oral small molecule inhibitor targeting multiple neurotoxic proteins. It decreases the production of amyloid precursor protein (APP) by inhibiting the translation of its mRNA [1].</p>
    Formula:C24H29N3O8
    Color and Shape:Solid
    Molecular weight:487.50

    Ref: TM-T85929

  • Sulamserod hydrochloride
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    Sulamserod hydrochloride

    CAS:
    <p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>
    Formula:C19H29Cl2N3O5S
    Color and Shape:Solid
    Molecular weight:482.42

    Ref: TM-T201756

  • DA-8031
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    DA-8031

    CAS:
    <p>DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).</p>
    Formula:C21H24N2O2
    Color and Shape:Solid
    Molecular weight:336.43

    Ref: TM-T201663

  • CVN766
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    CVN766

    CAS:
    <p>CVN766 is an orally active orexin 1 receptor antagonist with blood-brain permeability, demonstrating IC50 values of 8 nM for OX1R and &gt;10 μM for OX2R. CVN766 can be used to study schizophrenia [1].</p>
    Formula:C20H21F3N8O
    Color and Shape:Solid
    Molecular weight:446.43

    Ref: TM-T86110

  • Nafimidone hydrochloride
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    Nafimidone hydrochloride

    CAS:
    <p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>
    Formula:C15H13ClN2O
    Color and Shape:Solid
    Molecular weight:272.73

    Ref: TM-T201733

  • RTIOXA-43
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    RTIOXA-43

    CAS:
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Formula:C37H37N5O5S
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:663.79

    Ref: TM-T87345

  • SEP-363856 mesylate
    Targetmol
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    SEP-363856 mesylate

    CAS:
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Formula:C10H17NO4S2
    Color and Shape:Solid
    Molecular weight:279.38

    Ref: TM-T201258

  • Geissoschizoline
    Targetmol
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    Geissoschizoline

    CAS:
    <p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>
    Formula:C19H26N2O
    Color and Shape:Solid
    Molecular weight:298.42

    Ref: TM-T72733