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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Sucunamostat

    CAS:
    <p>Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.</p>
    Formula:C22H22N4O8
    Color and Shape:Solid
    Molecular weight:470.438
  • KKI-5

    CAS:
    <p>KKI 5: Serine protease inhibitor, blocks kallikrein &amp; plasmin, potential for cancer therapy &amp; angioedema treatment.</p>
    Formula:C35H55N11O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:773.88
  • Sofosbuvir impurity H


    <p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>
    Formula:C29H33FN3O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:633.56
  • Fibrinopeptide B, human

    CAS:
    <p>Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.</p>
    Formula:C66H93N19O25
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1552.56
  • CRA-2059

    CAS:
    <p>CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.</p>
    Formula:C34H46N12O8
    Purity:97.68%
    Color and Shape:Solid
    Molecular weight:750.818
  • ZG36


    <p>ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial</p>
    Color and Shape:Odour Solid
  • PSI-7409

    CAS:
    <p>PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).</p>
    Formula:C10H16FN2O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.16
  • Cys-TAT(47-57) acetate(583836-55-9 Free base)


    <p>Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.</p>
    Formula:C69H128N34O16S
    Purity:95.1100%
    Color and Shape:Solid
    Molecular weight:1722.04
  • 7-Methoxy obtusifolin

    CAS:
    <p>7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentration</p>
    Formula:C17H14O6
    Color and Shape:Solid
    Molecular weight:314.29
  • MK-6169

    CAS:
    <p>MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.</p>
    Formula:C54H62FN9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1016.2
  • Recombinant Trypsin


    <p>Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.</p>
  • Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

    CAS:
    <p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>
    Formula:C47H64N14O10
    Color and Shape:Solid
    Molecular weight:985.1
  • Emtricitabine S-oxide

    CAS:
    <p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>
    Formula:C8H10FN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:263.25
  • JC-10

    CAS:
    <p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>
    Formula:C25H29Cl2IN4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:583.34
  • AE-3763

    CAS:
    <p>AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).</p>
    Formula:C23H34F3N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.54
  • Sadopeptins B


    <p>Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18
  • Relacatib

    CAS:
    <p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64
  • L-Methionine-DL-sulfoximine

    CAS:
    <p>MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.</p>
    Formula:C5H12N2O3S
    Purity:99.56% - ≥98%
    Color and Shape:White Crystalline Powder
    Molecular weight:180.23
  • Nostosin G


    <p>Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).</p>
    Formula:C25H33N5O6
    Color and Shape:Solid
    Molecular weight:499.56
  • Ichorcumab

    CAS:
    <p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>
    Color and Shape:Liquid
  • Sofosbuvir impurity A

    CAS:
    <p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>
    Formula:C22H29FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.45
  • CRA-2059 TFA


    <p>CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>
    Color and Shape:Solid
  • HCV-IN-7 hydrochloride

    CAS:
    <p>HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>
    Formula:C40H50Cl2N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:841.85
  • Rivulariapeptolides 1121


    <p>Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).</p>
    Formula:C56H83N9O15
    Color and Shape:Solid
    Molecular weight:1122.31
  • Sofosbuvir impurity N

    CAS:
    <p>Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>
    Formula:C20H25FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:501.404
  • TAPI1 acetate


    <p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>
    Formula:C28H41N5O7
    Purity:98.82% - 99.94%
    Color and Shape:Solid
    Molecular weight:559.65
  • RJS308


    <p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42
  • TMC647055 Choline salt


    <p>TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).</p>
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91
  • Cathepsin C-IN-6


    <p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid
  • TWH106


    <p>TWH106 is an inhibitor of the cyclophilin (Cyp) enzyme, exhibiting strong affinity for CypA and CypB with dissociation constants (KD) of 53 nM and 139 nM, respectively. It effectively inhibits the replication of HIV and HCV, demonstrating antiviral activity.</p>
    Color and Shape:Odour Solid
  • PSI-353661

    CAS:
    <p>PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.</p>
    Formula:C24H32FN6O8P
    Color and Shape:Solid
    Molecular weight:582.52
  • Thrombin (MW 37kDa)

    CAS:
    <p>Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:37kDa
  • Hepcidin-1 (mouse)

    CAS:
    <p>Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.</p>
    Formula:C111H169N31O35S8
    Color and Shape:Solid
    Molecular weight:2754.24
  • Procizumab


    <p>Procizumab is a humanized IgG1 antibody that targets dipeptidyl peptidase 3 (DPP3). It shows potential for investigating sepsis. For the isotype control, refer to HumanIgG1kappa, Isotype Control.</p>
    Color and Shape:Odour Liquid
  • Histatin 5

    CAS:
    <p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>
    Formula:C133H195N51O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3036.29
  • Alisporivir

    CAS:
    <p>Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.</p>
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64
  • Ellipyrone B


    <p>Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50</p>
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57
  • Dutogliptin tartrate

    CAS:
    <p>Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.</p>
    Formula:C14H26BN3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.18
  • Tyrosinase-IN-36


    <p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>
    Color and Shape:Odour Solid
  • PS 915

    CAS:
    <p>PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.</p>
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08
  • Befovacimab

    CAS:
    <p>Befovacimab, a human IgG2 antibody, targets TFPI for hemophilia A/B research.</p>
    Color and Shape:Liquid
  • α 1 Antichymotrypsin, Human Plasma

    CAS:
    <p>Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.</p>
    Color and Shape:Solid
  • TR-107

    CAS:
    <p>TR-107 (Anticancer agent 230) is a mitochondrial protease ClpP activator that inhibits tumor growth in the MDA-MB-231 xenograft model.</p>
    Formula:C22H19ClN4O
    Color and Shape:Soild
    Molecular weight:390.87
  • PF 00356231

    CAS:
    <p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>
    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5
  • Leptosphaerodione

    CAS:
    <p>Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.</p>
    Formula:C21H22O5
    Color and Shape:Solid
    Molecular weight:354.4
  • EP 171

    CAS:
    <p>EP 171 is a potent agonist of TP-receptors.</p>
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47
  • Histatin 5 TFA


    <p>Histatin 5 TFA effectively inhibits host matrix metalloproteinases (MMP-2) and (MMP-9), demonstrating inhibition concentrations (IC 50s) of 0.57 μM and 0.25 μM</p>
    Formula:C135H196N51F3O35
    Color and Shape:Solid
    Molecular weight:3150.31
  • (Iso)-Fosdevirine

    CAS:
    <p>(Iso)-Fosdevirine ( (Iso)-GSK2248761), a reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological diseases.</p>
    Formula:C20H17ClN3O3P
    Purity:99.93%
    Color and Shape:Soild
    Molecular weight:413.79
  • HIV-1 inhibitor-6 

    CAS:
    <p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32
  • Ala-Phe-Pro-pNA TFA


    <p>Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.</p>
    Color and Shape:Odour Solid
  • APC-6860

    CAS:
    <p>APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.</p>
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13
  • Sofosbuvir impurity M

    CAS:
    <p>Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>
    Formula:C22H30N3O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:527.467
  • BPHA

    CAS:
    <p>BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.</p>
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46
  • Obtusifolin-2-O-glucoside

    CAS:
    <p>Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].</p>
    Formula:C22H22O10
    Color and Shape:Solid
    Molecular weight:446.4
  • Z-Leu-Tyr-Chloromethylketone

    CAS:
    <p>Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].</p>
    Formula:C24H29ClN2O5
    Color and Shape:Solid
    Molecular weight:460.95
  • NS5A-IN-4

    CAS:
    <p>NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.</p>
    Formula:C47H48N8O6
    Color and Shape:Solid
    Molecular weight:820.93
  • HIV-1 Rev (34-50)

    CAS:
    <p>HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.</p>
    Formula:C97H173N51O24
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:2437.74
  • Talabostat

    CAS:
    <p>Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.</p>
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07
  • Nitidanin


    <p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>
    Formula:C21H24O8
    Color and Shape:Solid
    Molecular weight:404.415
  • Tyrosinase/elastase-IN-1


    <p>Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase</p>
    Formula:C33H52O5
    Color and Shape:Solid
    Molecular weight:528.76
  • Clathrin-IN-1

    CAS:
    <p>Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.</p>
    Formula:C20H13BrN2O3S2
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:473.36
  • GSK2336805

    CAS:
    <p>GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.</p>
    Formula:C42H52N8O8
    Color and Shape:Solid
    Molecular weight:796.91
  • CL 82198 hydrochloride

    CAS:
    <p>CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.</p>
    Formula:C17H23ClN2O3
    Color and Shape:Solid
    Molecular weight:338.83
  • Dansyl-Glu-Gly-Arg-Chloromethylketone

    CAS:
    <p>Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated</p>
    Formula:C26H36ClN7O7S
    Color and Shape:Solid
    Molecular weight:626.12
  • VPLSLYSG

    CAS:
    <p>VPLSLYSG, an octapeptide, degraded by MMP-9, MMP-1, MMP-2; potential MMP substrate uses.</p>
    Formula:C39H62N8O12
    Color and Shape:Solid
    Molecular weight:834.96
  • Recombinant Proteinase K


    <p>Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.</p>
    Color and Shape:Solid
  • Z-Arg-Arg-βNA acetate

    CAS:
    <p>Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.</p>
    Formula:C32H43N9O6
    Color and Shape:Solid
    Molecular weight:649.74
  • MMP-3 Inhibitor acetate


    <p>MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.</p>
    Formula:C29H50N10O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:746.83
  • Peptide 74

    CAS:
    <p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>
    Formula:C62H107N23O20S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1558.79
  • Sitagliptin fenilalanil hydrochloride

    CAS:
    <p>Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.</p>
    Formula:C25H25ClF6N6O2
    Color and Shape:Solid
    Molecular weight:590.95
  • PROTAC 20S proteasome subunit β5 degrader 2


    <p>PROTAC 20S proteasome subunit β5 degrader 2 is a PROTAC degrader targeting the 20S proteasome subunit β5 (20Sproteasomesubunit β5), with a DC50 of 0.16 μM. It inhibits the proliferation of FaDu cancer cells, showcasing an IC50 of 0.23 μM. Additionally, PROTAC20Sproteasomesubunit β5 degrader 2 demonstrates antitumor activity in a mouse model.</p>
    Color and Shape:Odour Solid
  • AMG-222

    CAS:
    <p>AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.</p>
    Formula:C32H39N9O3
    Color and Shape:Solid
    Molecular weight:597.71
  • PPACK II

    CAS:
    <p>PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .</p>
    Formula:C25H33ClN6O3
    Color and Shape:Solid
    Molecular weight:501.02
  • MMP-3 Inhibitor

    CAS:
    <p>MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.</p>
    Formula:C27H46N10O9S
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:686.78
  • HCV-IN-4

    CAS:
    <p>HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.</p>
    Formula:C52H58FN9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:956.07
  • HIV-1 protease-IN-14


    <p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>
    Color and Shape:Odour Solid
  • Leptosin D

    CAS:
    <p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>
    Formula:C25H24N4O3S2
    Color and Shape:Solid
    Molecular weight:492.61
  • LXE408 fumarate


    <p>LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.</p>
    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:559.51
  • Iso-VQA-ACC acetate


    <p>Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.</p>
    Color and Shape:Odour Solid
  • HCV-IN-41

    CAS:
    <p>HCV-IN-41: potent HCV inhibitor; EC50 - 0.006762 nM (1b), 5.183 nM (2a), 1.365 nM (3a), 142.2 nM (4a); hinders RNA replication.</p>
    Formula:C48H56N6O8
    Color and Shape:Solid
    Molecular weight:844.99
  • MMP-9/MMP-13 Inhibitor I

    CAS:
    <p>MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.</p>
    Formula:C25H25N3O6S
    Color and Shape:Solid
    Molecular weight:495.55
  • 15,16-Dihydrotanshindiol C


    <p>15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.</p>
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.337
  • Grazoprevir potassium salt

    CAS:
    <p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805
  • RXP470

    CAS:
    <p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818
  • 6,6′-Dihydroxythiobinupharidine

    CAS:
    <p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>
    Formula:C30H42N2O4S
    Color and Shape:Solid
    Molecular weight:526.73
  • Ac-PAL-AMC

    CAS:
    <p>Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.</p>
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57
  • Tyrosinase-IN-38


    <p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>
    Color and Shape:Odour Solid
  • SFTI-1

    CAS:
    <p>SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.</p>
    Formula:C67H104N18O18S2
    Color and Shape:Solid
    Molecular weight:1513.78
  • PROTAC CG167


    <p>PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)</p>
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47
  • FFAGLDD TFA


    <p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>
    Formula:C39H50F3N7O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:897.85
  • 5-epi-Arvestonate A

    CAS:
    <p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>
    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37
  • VD2173

    CAS:
    <p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81
  • Bortezomib analog


    <p>Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.</p>
    Color and Shape:Odour Solid
  • NIM811

    CAS:
    <p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635
  • Pentosan Polysulfate

    CAS:
    <p>Pentosan Polysulfate: anti-HIV, anti-inflammatory, supports cartilage, treats interstitial cystitis.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • Rivulariapeptolides 1155


    <p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>
    Formula:C59H81N9O15
    Color and Shape:Solid
    Molecular weight:1156.33
  • CP-346086 dihydrate

    CAS:
    <p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>
    Formula:C26H26F3N5O3
    Color and Shape:Solid
    Molecular weight:513.521
  • Cathepsin L-IN-3

    CAS:
    <p>Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.</p>
    Formula:C41H49N7O4S
    Color and Shape:Solid
    Molecular weight:735.94
  • Anticancer agent 114


    <p>Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.</p>
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37
  • ADAM8-IN-1

    CAS:
    <p>ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.</p>
    Formula:C44H44Br4N6O12S2
    Color and Shape:Solid
    Molecular weight:1232.6