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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Sofosbuvir impurity A

    CAS:
    <p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>
    Formula:C22H29FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.45
  • CP-346086 dihydrate

    CAS:
    <p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>
    Formula:C26H26F3N5O3
    Color and Shape:Solid
    Molecular weight:513.521
  • Zetomipzomib maleate

    CAS:
    <p>Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.</p>
    Formula:C34H46N4O12
    Color and Shape:Solid
    Molecular weight:702.758
  • Leptosin D

    CAS:
    <p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>
    Formula:C25H24N4O3S2
    Color and Shape:Solid
    Molecular weight:492.61
  • Sofosbuvir impurity H


    <p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>
    Formula:C29H33FN3O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:633.56
  • TAPI1 acetate


    <p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>
    Formula:C28H41N5O7
    Purity:98.82% - 99.94%
    Color and Shape:Solid
    Molecular weight:559.65
  • HCVP-IN-1

    CAS:
    <p>HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.</p>
    Formula:C30H34FN5O3
    Color and Shape:Solid
    Molecular weight:531.632
  • TMC647055 Choline salt


    <p>TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).</p>
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91
  • Cathepsin C-IN-6


    <p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid
  • Sitagliptin fenilalanil hydrochloride

    CAS:
    <p>Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.</p>
    Formula:C25H25ClF6N6O2
    Color and Shape:Solid
    Molecular weight:590.95
  • Cyanopeptolin 954

    CAS:
    <p>Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.</p>
    Formula:C46H63ClN8O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:955.5
  • Neutrophil elastase inhibitor 4


    <p>Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.</p>
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4
  • HCV-IN-41

    CAS:
    <p>HCV-IN-41: potent HCV inhibitor; EC50 - 0.006762 nM (1b), 5.183 nM (2a), 1.365 nM (3a), 142.2 nM (4a); hinders RNA replication.</p>
    Formula:C48H56N6O8
    Color and Shape:Solid
    Molecular weight:844.99
  • MMP-9/MMP-13 Inhibitor I

    CAS:
    <p>MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.</p>
    Formula:C25H25N3O6S
    Color and Shape:Solid
    Molecular weight:495.55
  • EP 171

    CAS:
    <p>EP 171 is a potent agonist of TP-receptors.</p>
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47
  • Peptide 74

    CAS:
    <p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>
    Formula:C62H107N23O20S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1558.79
  • Sofosbuvir impurity J

    CAS:
    <p>Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>
    Formula:C22H30FN4O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.47
  • HCV-IN-4

    CAS:
    <p>HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.</p>
    Formula:C52H58FN9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:956.07
  • BAY 1217224

    CAS:
    <p>BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.</p>
    Formula:C24H27ClFN3O5
    Color and Shape:Solid
    Molecular weight:491.94
  • Relacatib

    CAS:
    <p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64