
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(37 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(502 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 992 products of "Proteases/Proteasome"
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N-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Formula:C33H36N6O6Purity:98%Color and Shape:White To Off-White PowderMolecular weight:612.68JC-10
CAS:JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.Formula:C25H29Cl2IN4Purity:95%Color and Shape:SolidMolecular weight:583.34Fibrinopeptide B, human
CAS:Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formula:C66H93N19O25Purity:98%Color and Shape:SolidMolecular weight:1552.56Ac-PLVE-FMK
CAS:Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].Formula:C25H41FN4O7Purity:98%Color and Shape:SolidMolecular weight:528.61Bortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Color and Shape:Odour SolidCRA-2059 hydrochloride
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Color and Shape:Solid5-epi-Arvestonate A
CAS:5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.
Formula:C16H26O5Color and Shape:SolidMolecular weight:298.37ADAM8-IN-1
CAS:ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.
Formula:C44H44Br4N6O12S2Color and Shape:SolidMolecular weight:1232.6FFAGLDD
"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."Formula:C37H49N7O12Purity:98%Color and Shape:SolidMolecular weight:783.82PS 915
CAS:PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.Formula:C27H36ClN7O6Purity:98%Color and Shape:SolidMolecular weight:590.08Chymotrypsinogen
CAS:Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .Color and Shape:SolidHCV-IN-4
CAS:HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.Formula:C52H58FN9O8Purity:98%Color and Shape:SolidMolecular weight:956.07MMP-3 Inhibitor
CAS:MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.Formula:C27H46N10O9SPurity:98.87%Color and Shape:SolidMolecular weight:686.78Ref: TM-T37048
1mg77.00€5mg197.00€10mg294.00€25mg497.00€50mg717.00€100mg982.00€500mg1,998.00€1mL*10mM (DMSO)210.00€Ellipyrone B
Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50Formula:C25H38O7Color and Shape:SolidMolecular weight:450.57PSI-353661
CAS:PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.Formula:C24H32FN6O8PColor and Shape:SolidMolecular weight:582.52HCVP-IN-1
CAS:HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.Formula:C30H34FN5O3Color and Shape:SolidMolecular weight:531.632NIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Formula:C62H111N11O12Purity:98%Color and Shape:SolidMolecular weight:1202.635RJS308
RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)Formula:C63H75N13O11SColor and Shape:SolidMolecular weight:1222.42HCV-IN-7 hydrochloride
CAS:HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Formula:C40H50Cl2N8O6SPurity:98%Color and Shape:SolidMolecular weight:841.85Ac-Phe-Gly-pNA
CAS:Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .Formula:C19H20N4O5Color and Shape:SolidMolecular weight:384.39

