
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(46 products)
- HIV Protease(508 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(55 products)
- Proteasome(86 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 980 products of "Proteases/Proteasome"
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PF-00356231 hydrochloride
CAS:PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.Formula:C25H21ClN2O3SPurity:98.39%Color and Shape:SolidMolecular weight:464.96Tyrosinase-IN-5
CAS:Tyrosinase-IN-5 (16c) inhibits tyrosinase with 0.02 μM IC50, reduces melanogenesis, and is low-toxicity.Formula:C18H13N3O6Color and Shape:SolidMolecular weight:367.31BRD-8899
CAS:BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].Formula:C17H22N4O3SColor and Shape:SolidMolecular weight:362.45GS-9256
CAS:GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].Formula:C46H56ClF2N6O8PSPurity:98%Color and Shape:SolidMolecular weight:957.46Z-LLF-CHO
CAS:Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.Formula:C29H39N3O5Purity:98%Color and Shape:SolidMolecular weight:509.64BC-23
CAS:BC-23 (NSC 45382) is a proteasome inhibitor with antitumor and antimicrobial activity for the study of leukemia and small cell lung cancer.Formula:C21H14ClN3O4SPurity:98%Color and Shape:SolidMolecular weight:439.87Gemigliptin Tartrate(911637-19-9 free base)
CAS:Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4).Formula:C22H25F8N5O8Purity:>99.99%Color and Shape:SolidMolecular weight:639.45HCV-IN-36
CAS:HCV-IN-36: oral HCV inhibitor, EC50 0.016 μM, CC50 8.78 μM, potent antiviral.Formula:C30H36ClN5Color and Shape:SolidMolecular weight:502.09NNGH
CAS:NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.Formula:C13H20N2O5SPurity:98.41%Color and Shape:SolidMolecular weight:316.37PK44 phosphate
CAS:PK44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 15.8 nM).Formula:C17H19F5N7O5PColor and Shape:SolidMolecular weight:527.349AGLME
CAS:AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.Formula:C11H21N3O4Color and Shape:SolidMolecular weight:259.3GLS1 Inhibitor-3
CAS:GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.Formula:C30H32N10O2SColor and Shape:SolidMolecular weight:596.71ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99Tanomastat
CAS:Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.Formula:C23H19ClO3SPurity:98%Color and Shape:SolidMolecular weight:410.91MMP13-IN-4
CAS:MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].Formula:C21H17BrN4O5Purity:98%Color and Shape:SolidMolecular weight:485.29BI-L 45XX
CAS:BI-L 45XX, an anti-inflammatory benzimidazole derivative, has inhibitory effects on neutrophil function.Formula:C10H9F3N2O2SColor and Shape:SolidMolecular weight:278.25Tyrphostin 47
CAS:Tyrphostin 47 inhibits the protein-tyrosine kinase activity of EGF-R.Formula:C10H8N2O2SColor and Shape:SolidMolecular weight:220.25Levovirin valinate HCl
CAS:Levovirin valinate HCl is a valine ester prodrug of levovirin as a new investigational drug for the therapy of the hepatitis C virus.Formula:C13H22ClN5O6Purity:98%Color and Shape:SolidMolecular weight:379.8Ici 186756
CAS:Ici 186756 is a novel, effective, and selective inhibitor of human neutrophil elastase.Formula:C33H49N5O9Purity:98%Color and Shape:SolidMolecular weight:659.77Chymase-IN-2
CAS:Chymase-IN-2 is a modulator of chymase.Formula:C19H15ClF2NO3PSPurity:98%Color and Shape:SolidMolecular weight:441.82
