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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Galegenimab

    CAS:
    <p>Galegenimab (FHTR 2163; RG 6147; RO 7171009) is an HTRA1 antibody fragment for AMD research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Zampilimab

    CAS:
    <p>Zampilimab (UCB-7858) is a humanised monoclonal antibody targeting TGM2, inhibits the cross-linking transamidase activity of TG2, renal fibrosis.</p>
    Purity:95%
    Color and Shape:Liquid
  • HCV-IN-30

    CAS:
    <p>HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).</p>
    Formula:C36H44N6O4
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:624.77
  • Carboxypeptidase G2 (CPG2) Inhibitor

    CAS:
    <p>Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.</p>
    Formula:C13H15NO6S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:313.33
  • Cathepsin Inhibitor 1

    CAS:
    <p>Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.</p>
    Formula:C20H24ClN5O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:401.89
  • PK44 phosphate

    CAS:
    <p>PK44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 15.8 nM).</p>
    Formula:C17H19F5N7O5P
    Color and Shape:Solid
    Molecular weight:527.349
  • DPP-4-IN-2

    CAS:
    <p>DPP-4-IN-2, analog of Alogliptin with 79 nM IC50, is a research tool for diabetes.</p>
    Formula:C18H18N6O
    Color and Shape:Solid
    Molecular weight:334.38
  • Alvelestat tosylate

    CAS:
    <p>Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.</p>
    Formula:C32H30F3N5O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:717.73
  • BAY8040

    CAS:
    <p>BAY8040 is a potent selective human neutrophilic elastase inhibitor with excellent potency and selectivity with promising pharmacokinetic characteristics.</p>
    Formula:C21H16F3N5O2
    Color and Shape:Solid
    Molecular weight:427.38
  • HCV-IN-33

    CAS:
    <p>HCV-IN-33 (Compound (S)-3i) is an inhibitor of HCV entry.</p>
    Formula:C31H36ClN5
    Color and Shape:Solid
    Molecular weight:514.1
  • AA10 TG2 inhibitor

    CAS:
    <p>AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).</p>
    Formula:C32H36N4O5
    Color and Shape:Solid
    Molecular weight:556.65
  • DPP-4-IN-1

    CAS:
    <p>DPP-4-IN-1 inhibits DPP-4 with 49 nM IC50, ideal for diabetes study, akin to Alogliptin.</p>
    Formula:C19H19ClN6
    Color and Shape:Solid
    Molecular weight:366.85
  • (Rac)-Tanomastat

    CAS:
    <p>Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.</p>
    Formula:C23H19ClO3S
    Color and Shape:Solid
    Molecular weight:410.91
  • Thrombin Inhibitor 2

    CAS:
    <p>Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.</p>
    Formula:C19H16ClF3N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.82
  • PSI-7409 tetrasodium

    CAS:
    <p>PSI-7409 tetrasodium, a sofosbuvir metabolite, inhibits GT 1b, 2a, 3a, 4a NS5B polymerases with IC50s of 1.6, 2.8, 0.7, 2.6 μM.</p>
    Formula:C10H16FN2Na4O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:592.117
  • CAY10704

    CAS:
    <p>CAY10704: Potent HCV inhibitor, EC50=17 nM, low cytotoxicity, good in mice, liver-targeted, not hepatotoxic, weak against dengue.</p>
    Formula:C18H20Cl2N2
    Color and Shape:Solid
    Molecular weight:335.27
  • ASPER-29

    CAS:
    <p>ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.</p>
    Formula:C31H29BrN2O5S
    Color and Shape:Solid
    Molecular weight:621.54
  • Evogliptin HCl

    CAS:
    <p>Evogliptin (DA-1229), a DPP4 inhibitor, enhances insulin sensitivity and delays diabetes onset.</p>
    Formula:C19H27ClF3N3O3
    Color and Shape:Solid
    Molecular weight:437.88
  • LY 806303

    CAS:
    <p>LY 806303 is a highly selective thrombin inhibitor.</p>
    Formula:C16H14O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:318.34
  • Elasnin

    CAS:
    <p>Elasnin is a reversible inhibitor of elastase for human granulocyte and pancreatic enzymes with IC50 values of 1.3 and 30 µg/ml, respectively.</p>
    Formula:C24H40O4
    Color and Shape:Solid
    Molecular weight:392.57