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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1044 products of "Proteases/Proteasome"

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  • Ro 09-1679

    CAS:
    <p>Ro 09-1679 is a thrombin inhibitor.</p>
    Formula:C22H39N9O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:525.6
  • Cathepsin L/S-IN-1


    <p>Cathepsin L/S-IN-1 inhibits Cathepsin L &amp; S (IC50: 4.10 &amp; 1.79 μM) and reduces metastasis in pancreatic cancer cells.</p>
    Formula:C29H33BrN4O4S
    Color and Shape:Solid
    Molecular weight:613.57
  • NNGH

    CAS:
    <p>NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.</p>
    Formula:C13H20N2O5S
    Purity:98.41%
    Color and Shape:Solid
    Molecular weight:316.37
  • Navuridine

    CAS:
    <p>Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.</p>
    Formula:C9H11N5O4
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:253.22
  • ZM223 hydrochloride (2031177-48-5 free base)


    <p>ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.</p>
    Formula:C23H18ClF3N4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.99
  • Diprotin B

    CAS:
    <p>Diprotin B is a dipeptidyl peptidase IV inhibitor.</p>
    Formula:C16H29N3O4
    Purity:98%
    Color and Shape:White Lyophilized Powder
    Molecular weight:327.42
  • HCV-IN-3

    CAS:
    <p>HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).</p>
    Formula:C13H11F2NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:235.23
  • Calpain Inhibitor XII

    CAS:
    <p>Calpain Inhibitor XII (Z-L-Nva-CONH-CH2-2-Py) is a calpain I inhibitor that inhibits calpain II and cathepsin B.</p>
    Formula:C26H34N4O5
    Color and Shape:Solid
    Molecular weight:482.57
  • Flovagatran

    CAS:
    <p>Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.</p>
    Formula:C27H36BN3O7
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:525.4
  • RO-9187

    CAS:
    <p>RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).</p>
    Formula:C9H12N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:284.23
  • Plasma kallikrein-IN-3

    CAS:
    <p>Plasma kallikrein-IN-3 is a potent inhibitor (IC50: 0.15 μM) used in hereditary angioedema and diabetic eye disease research.</p>
    Formula:C20H23N5O2
    Color and Shape:Solid
    Molecular weight:365.43
  • 2-MPPA

    CAS:
    <p>2-MPPA (GPI-5693) is a GCP II inhibitor and NAALADase inhibitor, used in research on neurodegenerative diseases.</p>
    Formula:C8H14O4S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:206.26
  • Calpain-2-IN-1

    CAS:
    <p>Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory.</p>
    Formula:C28H37N3O7
    Color and Shape:Solid
    Molecular weight:527.61
  • Tyrosinase-IN-10

    CAS:
    <p>Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme'</p>
    Formula:C16H12O4
    Color and Shape:Solid
    Molecular weight:268.26
  • TAPI-0

    CAS:
    <p>TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.</p>
    Formula:C24H32N4O5
    Color and Shape:Solid
    Molecular weight:456.53
  • NAAA-IN-2

    CAS:
    <p>NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.</p>
    Formula:C11H13N3O2S
    Color and Shape:Solid
    Molecular weight:251.3
  • HCV-IN-35

    CAS:
    <p>HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.</p>
    Formula:C30H36ClN5
    Color and Shape:Solid
    Molecular weight:502.09
  • MMP-1-IN-1


    <p>MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .</p>
    Formula:C14H17ClN2O3
    Color and Shape:Solid
    Molecular weight:296.75
  • Calpain Inhibitor XI

    CAS:
    <p>Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders.</p>
    Formula:C26H40N4O6
    Color and Shape:Solid
    Molecular weight:504.62
  • (3S,4S)-A2-32-01


    <p>(3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .</p>
    Formula:C19H27NO2
    Color and Shape:Solid
    Molecular weight:301.42