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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1044 products of "Proteases/Proteasome"

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  • Azo-Resveratrol

    CAS:
    <p>Azo-Resveratrol is an analog of Resveratrol used as a potent tyrosinase inhibitor.</p>
    Formula:C12H10N2O3
    Color and Shape:Solid
    Molecular weight:230.22
  • AM 4299 B

    CAS:
    <p>AM 4299 B is a novel inhibitor of a thiol protease.</p>
    Formula:C16H27N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.4
  • HCV-IN-34

    CAS:
    <p>HCV-IN-35, an oral HCV blocker, has an EC50 of 0.010 μM and a CC50 of 7.5 μM, indicating strong antiviral effects.</p>
    Formula:C31H36ClN5
    Color and Shape:Solid
    Molecular weight:514.1
  • MDL 27399

    CAS:
    <p>MDL 27399 suppresses human neutrophil cathepsin G.</p>
    Formula:C26H36N4O8
    Color and Shape:Solid
    Molecular weight:532.59
  • Tyrosinase-IN-7

    CAS:
    <p>Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.</p>
    Formula:C15H10O5
    Purity:99%
    Color and Shape:Solid
    Molecular weight:270.24
  • CAA0225

    CAS:
    <p>CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.</p>
    Formula:C28H29N3O5
    Color and Shape:Solid
    Molecular weight:487.55
  • BC-05

    CAS:
    <p>BC-05, an orally active inhibitor targeting CD13 and the proteasome, displays potent inhibition with IC50 values of 0.13 μM against human CD13 and 1.39 μM for</p>
    Formula:C21H29BN2O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:464.27
  • RID-F

    CAS:
    <p>RID-F is an inhibitor of the nonpeptidic proteasome.</p>
    Formula:C38H50N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:566.82
  • AL-9

    CAS:
    <p>AL-9 is a GT-1b and GT-2a replication inhibitor.</p>
    Formula:C23H22N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.45
  • Immunoproteasome inhibitor 1

    CAS:
    <p>Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.</p>
    Formula:C20H26N2O4
    Color and Shape:Solid
    Molecular weight:358.43
  • PMPA sodium

    CAS:
    <p>PMPA sodium is a potent and selective glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase) inhibitor.</p>
    Formula:C6H11Na4O7P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:318.08
  • JO146

    CAS:
    <p>JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂,其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM,可应用于细菌感染的抑制。</p>
    Formula:C31H44N3O7P
    Color and Shape:Solid
    Molecular weight:601.67
  • L-873724

    CAS:
    <p>L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.</p>
    Formula:C23H26F3N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.53
  • (R)-ND-336

    CAS:
    <p>(R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.</p>
    Formula:C16H18ClNO3S2
    Color and Shape:Solid
    Molecular weight:371.89
  • Tyrosinase-IN-11

    CAS:
    <p>Tyrosinase-IN-11: potent inhibitor, IC50 - 50nM/64nM (L-tyrosinase/L-dopa), antioxidant, low toxicity, for hyperpigmentation study.</p>
    Formula:C15H14O5
    Color and Shape:Solid
    Molecular weight:274.27
  • Kallikrein 5-IN-2

    CAS:
    <p>Kallikrein 5-IN-2 inhibits KLK5 (pIC50=7.1); may normalize skin shedding, lessen inflammation &amp; itching.</p>
    Formula:C23H22N6O
    Color and Shape:Solid
    Molecular weight:398.46
  • VA4 TG2 inhibitor

    CAS:
    <p>VA4 is a novel irreversible TG2 transamidase site-specific inhibitor.</p>
    Formula:C33H41N5O6S
    Color and Shape:Solid
    Molecular weight:635.77
  • AZD5248

    CAS:
    <p>AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1).</p>
    Formula:C22H22N4O2
    Color and Shape:Solid
    Molecular weight:374.44
  • MMP-2/9-IN-1

    CAS:
    <p>MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.</p>
    Formula:C14H16IN7S
    Color and Shape:Solid
    Molecular weight:441.29
  • GLS1 Inhibitor-3

    CAS:
    <p>GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.</p>
    Formula:C30H32N10O2S
    Color and Shape:Solid
    Molecular weight:596.71